DE602004015454D1 - Verfahren und vorrichtung zur kontinuierlichen radioaktiven markierung von proteinen im grossen massstab - Google Patents

Verfahren und vorrichtung zur kontinuierlichen radioaktiven markierung von proteinen im grossen massstab

Info

Publication number
DE602004015454D1
DE602004015454D1 DE602004015454T DE602004015454T DE602004015454D1 DE 602004015454 D1 DE602004015454 D1 DE 602004015454D1 DE 602004015454 T DE602004015454 T DE 602004015454T DE 602004015454 T DE602004015454 T DE 602004015454T DE 602004015454 D1 DE602004015454 D1 DE 602004015454D1
Authority
DE
Germany
Prior art keywords
radioactive marking
proteins
scale
continuous
continuous radioactive
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602004015454T
Other languages
English (en)
Inventor
Raimo Pellikka
Steven W King
Peter Blaeuenstein
Pius A Schubiger
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Avid Bioservices Inc
Original Assignee
Peregrine Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Peregrine Pharmaceuticals Inc filed Critical Peregrine Pharmaceuticals Inc
Publication of DE602004015454D1 publication Critical patent/DE602004015454D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/13—Labelling of peptides
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/34—Size selective separation, e.g. size exclusion chromatography, gel filtration, permeation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/36—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving ionic interaction
    • B01D15/361—Ion-exchange
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T29/00—Metal working
    • Y10T29/49—Method of mechanical manufacture
    • Y10T29/496—Multiperforated metal article making
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T29/00—Metal working
    • Y10T29/49—Method of mechanical manufacture
    • Y10T29/49826—Assembling or joining
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/13—Tracers or tags
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/25375—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/25375—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.]
    • Y10T436/255—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.] including use of a solid sorbent, semipermeable membrane, or liquid extraction
DE602004015454T 2003-06-25 2004-06-25 Verfahren und vorrichtung zur kontinuierlichen radioaktiven markierung von proteinen im grossen massstab Active DE602004015454D1 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US48238703P 2003-06-25 2003-06-25
US49312103P 2003-08-07 2003-08-07
US49368903P 2003-08-08 2003-08-08
PCT/US2004/020492 WO2005003151A2 (en) 2003-06-25 2004-06-25 Method and apparatus for continuous large-scale radiolabeling of proteins

Publications (1)

Publication Number Publication Date
DE602004015454D1 true DE602004015454D1 (de) 2008-09-11

Family

ID=33568598

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602004015454T Active DE602004015454D1 (de) 2003-06-25 2004-06-25 Verfahren und vorrichtung zur kontinuierlichen radioaktiven markierung von proteinen im grossen massstab

Country Status (10)

Country Link
US (2) US7591953B2 (de)
EP (2) EP1964847A3 (de)
AT (1) ATE402947T1 (de)
AU (1) AU2004253924B2 (de)
CA (1) CA2527054C (de)
DE (1) DE602004015454D1 (de)
DK (1) DK1638989T3 (de)
HK (1) HK1087417A1 (de)
NZ (1) NZ543495A (de)
WO (1) WO2005003151A2 (de)

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AU2004253924B2 (en) * 2003-06-25 2009-07-30 Peregrine Pharmaceuticals, Inc. Method and apparatus for continuous large-scale radiolabeling of proteins
GB0520527D0 (en) * 2005-10-10 2005-11-16 Ge Healthcare Ltd Automated method
WO2009058737A1 (en) * 2007-10-29 2009-05-07 Pain Therapeutics, Inc. Disposable column system for purification of radiolabeled polypeptides
ITBO20080236A1 (it) * 2008-04-17 2009-10-18 Philogen Spa Apparecchiatura e metodo per la preparazione di medicinali contenenti sostanze radioattive.
ES2736224T3 (es) * 2011-02-22 2019-12-27 Promethera Biosciences Sa Sistema de llenado para proporcionar concentraciones y volúmenes uniformes y sus métodos
EP2766467A1 (de) * 2011-10-10 2014-08-20 DASGIP Information and Process Technology GmbH Biotechnologische vorrichtung mit einem bioreaktor, abgassteuerungsvorrichtung für einen bioreaktor und verfahren zur behandlung eines abgasstroms in einer biotechnologischen vorrichtung
DE102012209852A1 (de) 2012-06-12 2013-12-12 Robert Bosch Gmbh Abgasreinigungssystem zur Anordnung in einem Abgasstrang eines Kraftfahrzeuges, insbesondere eines Dieselkraftfahrzeugs
US20140329319A1 (en) * 2013-05-02 2014-11-06 Canadian Blood Services Apparatus and method for the immunocamouflage of biological cells
ES2843625T3 (es) 2014-06-18 2021-07-19 Alpha Therapy Solutions Ab Plataforma de proceso automático para la producción de radiofármacos marcados con astatina-211 [At-211]

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US4205050A (en) * 1976-06-17 1980-05-27 Chevron Research Company Method of reducing corrosion in sour gas sweetening systems
US4301139A (en) * 1979-06-21 1981-11-17 Ames-Yissum Ltd. Multilayer column chromatography specific binding assay method, test device and test kit
US4472371A (en) * 1979-10-29 1984-09-18 Summa Medical Corporation Radiolabeled antibody to anti-tumor associated antigen and process
US4362699A (en) 1981-03-10 1982-12-07 Bio Research, Inc. Apparatus for high pressure peptide synthesis
US4401646A (en) * 1981-05-08 1983-08-30 University Patents Inc. Method and apparatus for purifying materials radiolabeled with technetium-99m
US4775638A (en) 1985-05-08 1988-10-04 Centocor, Inc. Single vial technique for radiolabeling protein
US4724213A (en) 1985-05-24 1988-02-09 Northwestern University Murine hybridoma Lym-1 and diagnostic antibody produced thereby
US5019368A (en) 1989-02-23 1991-05-28 Cancer Biologics, Inc. Detection of necrotic malignant tissue and associated therapy
US4861581A (en) 1986-12-05 1989-08-29 Cancer Biologics, Inc. Detection of necrotic malignant tissue and associated therapy
DE3705686C2 (de) * 1987-02-23 1995-11-30 Boehringer Mannheim Gmbh Verfahren zur Bestimmung von Antikörpern
US4874601A (en) * 1987-04-17 1989-10-17 Merck & Co., Inc. Radiolabelling kit
US4861579A (en) 1988-03-17 1989-08-29 American Cyanamid Company Suppression of B-lymphocytes in mammals by administration of anti-B-lymphocyte antibodies
US6007817A (en) 1988-10-11 1999-12-28 University Of Southern California Vasopermeability enhancing immunoconjugates
US5194594A (en) 1990-09-07 1993-03-16 Techniclone, Inc. Modified antibodies
US5206346A (en) 1990-12-05 1993-04-27 E. I. Du Pont De Nemours And Company Method for iodination/purification
US5450847A (en) * 1991-04-22 1995-09-19 Schering Aktiengesellschaft Process for making doses formulation of contrast media from concentrate
ATE154722T1 (de) * 1991-05-01 1997-07-15 Mallinckrodt Medical Inc Verfahren zur förderung von flüssigen materialien und vorrichtung zur automatischen eluierung eines radionuklidgenerators
US6004555A (en) 1992-03-05 1999-12-21 Board Of Regents, The University Of Texas System Methods for the specific coagulation of vasculature
US5877289A (en) 1992-03-05 1999-03-02 The Scripps Research Institute Tissue factor compositions and ligands for the specific coagulation of vasculature
US6749853B1 (en) 1992-03-05 2004-06-15 Board Of Regents, The University Of Texas System Combined methods and compositions for coagulation and tumor treatment
US6036955A (en) 1992-03-05 2000-03-14 The Scripps Research Institute Kits and methods for the specific coagulation of vasculature
DK0627940T3 (da) 1992-03-05 2003-09-01 Univ Texas Anvendelse af immunokonjugater til diagnose og/eller terapi af vaskulariserede tumorer
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CA2345838C (en) * 2001-01-31 2010-02-02 Centre For Addiction And Mental Health Method for the synthesis of radiolabeled compounds
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AU2004253924B2 (en) * 2003-06-25 2009-07-30 Peregrine Pharmaceuticals, Inc. Method and apparatus for continuous large-scale radiolabeling of proteins

Also Published As

Publication number Publication date
EP1964847A2 (de) 2008-09-03
NZ543495A (en) 2009-04-30
WO2005003151A3 (en) 2005-04-07
ATE402947T1 (de) 2008-08-15
AU2004253924B2 (en) 2009-07-30
EP1964847A3 (de) 2008-09-17
AU2004253924A1 (en) 2005-01-13
US20050123474A1 (en) 2005-06-09
US20090312523A1 (en) 2009-12-17
EP1638989B1 (de) 2008-07-30
CA2527054A1 (en) 2005-01-13
EP1638989A2 (de) 2006-03-29
US7591953B2 (en) 2009-09-22
US8137540B2 (en) 2012-03-20
DK1638989T3 (da) 2008-11-17
CA2527054C (en) 2013-01-08
HK1087417A1 (en) 2006-10-13
WO2005003151A2 (en) 2005-01-13

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Legal Events

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