DE602004026701D1 - Implantierbares medizinprodukt zur selektiven modulation der abgabe von mitteln in situ - Google Patents

Implantierbares medizinprodukt zur selektiven modulation der abgabe von mitteln in situ

Info

Publication number
DE602004026701D1
DE602004026701D1 DE602004026701T DE602004026701T DE602004026701D1 DE 602004026701 D1 DE602004026701 D1 DE 602004026701D1 DE 602004026701 T DE602004026701 T DE 602004026701T DE 602004026701 T DE602004026701 T DE 602004026701T DE 602004026701 D1 DE602004026701 D1 DE 602004026701D1
Authority
DE
Germany
Prior art keywords
beneficial agent
medicines
situ
distribution
selective modulation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE602004026701T
Other languages
English (en)
Inventor
John F Shanley
Theodore J Parker
Neal L Eigler
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Innovational Holdings LLC
Original Assignee
Conor Medsystems LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Conor Medsystems LLC filed Critical Conor Medsystems LLC
Publication of DE602004026701D1 publication Critical patent/DE602004026701D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/0067—Catheters; Hollow probes characterised by the distal end, e.g. tips
    • A61M25/0068—Static characteristics of the catheter tip, e.g. shape, atraumatic tip, curved tip or tip structure
    • A61M25/007—Side holes, e.g. their profiles or arrangements; Provisions to keep side holes unblocked
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
    • A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
    • A61F2/91—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
    • A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
    • A61F2/91—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
    • A61F2/915—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M29/00—Dilators with or without means for introducing media, e.g. remedies
    • A61M29/02—Dilators made of swellable material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
    • A61M31/002—Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
    • A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
    • A61F2/91—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
    • A61F2/915—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other
    • A61F2002/91533—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other characterised by the phase between adjacent bands
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2250/0058—Additional features; Implant or prostheses properties not otherwise provided for
    • A61F2250/0067—Means for introducing or releasing pharmaceutical products into the body
    • A61F2250/0068—Means for introducing or releasing pharmaceutical products into the body the pharmaceutical product being in a reservoir
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/10—Balloon catheters
    • A61M2025/1043—Balloon catheters with special features or adapted for special applications
    • A61M2025/105—Balloon catheters with special features or adapted for special applications having a balloon suitable for drug delivery, e.g. by using holes for delivery, drug coating or membranes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/10—Balloon catheters
DE602004026701T 2003-03-28 2004-03-29 Implantierbares medizinprodukt zur selektiven modulation der abgabe von mitteln in situ Expired - Lifetime DE602004026701D1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US45890603P 2003-03-28 2003-03-28
US10/810,241 US20040202692A1 (en) 2003-03-28 2004-03-26 Implantable medical device and method for in situ selective modulation of agent delivery
PCT/US2004/009604 WO2004087251A1 (en) 2003-03-28 2004-03-29 Implantable medical device and method for in situ selective modulation of agent delivery

Publications (1)

Publication Number Publication Date
DE602004026701D1 true DE602004026701D1 (de) 2010-06-02

Family

ID=33135119

Family Applications (2)

Application Number Title Priority Date Filing Date
DE602004026701T Expired - Lifetime DE602004026701D1 (de) 2003-03-28 2004-03-29 Implantierbares medizinprodukt zur selektiven modulation der abgabe von mitteln in situ
DE602004022726T Expired - Lifetime DE602004022726D1 (de) 2003-03-28 2004-03-29 System zur Freisetzung eines Heilmittels

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE602004022726T Expired - Lifetime DE602004022726D1 (de) 2003-03-28 2004-03-29 System zur Freisetzung eines Heilmittels

Country Status (8)

Country Link
US (1) US20040202692A1 (de)
EP (2) EP1905477B1 (de)
JP (1) JP2006523132A (de)
AT (2) ATE464863T1 (de)
AU (1) AU2004226328B2 (de)
CA (1) CA2519717A1 (de)
DE (2) DE602004026701D1 (de)
WO (1) WO2004087251A1 (de)

Families Citing this family (83)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6783543B2 (en) * 2000-06-05 2004-08-31 Scimed Life Systems, Inc. Intravascular stent with increasing coating retaining capacity
US7341598B2 (en) 1999-01-13 2008-03-11 Boston Scientific Scimed, Inc. Stent with protruding branch portion for bifurcated vessels
US7351421B2 (en) * 1996-11-05 2008-04-01 Hsing-Wen Sung Drug-eluting stent having collagen drug carrier chemically treated with genipin
US7208010B2 (en) 2000-10-16 2007-04-24 Conor Medsystems, Inc. Expandable medical device for delivery of beneficial agent
US7713297B2 (en) 1998-04-11 2010-05-11 Boston Scientific Scimed, Inc. Drug-releasing stent with ceramic-containing layer
AU6539101A (en) * 2000-06-05 2001-12-17 G David Jang Intravascular stent with increasing coating retaining capacity
US20040073294A1 (en) 2002-09-20 2004-04-15 Conor Medsystems, Inc. Method and apparatus for loading a beneficial agent into an expandable medical device
US7727221B2 (en) 2001-06-27 2010-06-01 Cardiac Pacemakers Inc. Method and device for electrochemical formation of therapeutic species in vivo
US7842083B2 (en) 2001-08-20 2010-11-30 Innovational Holdings, Llc. Expandable medical device with improved spatial distribution
US7951392B2 (en) 2002-08-16 2011-05-31 Boston Scientific Scimed, Inc. Microarray drug delivery coatings
US7758636B2 (en) 2002-09-20 2010-07-20 Innovational Holdings Llc Expandable medical device with openings for delivery of multiple beneficial agents
AU2004226327A1 (en) 2003-03-28 2004-10-14 Innovational Holdings, Llc Implantable medical device with beneficial agent concentration gradient
US7972137B2 (en) 2003-06-30 2011-07-05 Rosen Gerald M Anti-microbial dental formulations for the prevention and treatment of oral mucosal disease
US7435256B2 (en) * 2003-11-06 2008-10-14 Boston Scientific Scimed, Inc. Method and apparatus for controlled delivery of active substance
CA2556212C (en) * 2004-02-13 2013-05-28 Conor Medsystems, Inc. Implantable drug delivery device including wire filaments
CA2559540A1 (en) 2004-06-08 2005-12-29 Advanced Stent Technologies, Inc. Stent with protruding branch portion for bifurcated vessels
EP1875560A4 (de) * 2005-04-05 2011-02-09 Univ Ohio State Diffusionsablieferungssysteme und herstellungsverfahren
US7540881B2 (en) 2005-12-22 2009-06-02 Boston Scientific Scimed, Inc. Bifurcation stent pattern
US8840660B2 (en) 2006-01-05 2014-09-23 Boston Scientific Scimed, Inc. Bioerodible endoprostheses and methods of making the same
US8089029B2 (en) 2006-02-01 2012-01-03 Boston Scientific Scimed, Inc. Bioabsorbable metal medical device and method of manufacture
US20070224235A1 (en) 2006-03-24 2007-09-27 Barron Tenney Medical devices having nanoporous coatings for controlled therapeutic agent delivery
US8187620B2 (en) 2006-03-27 2012-05-29 Boston Scientific Scimed, Inc. Medical devices comprising a porous metal oxide or metal material and a polymer coating for delivering therapeutic agents
US8048150B2 (en) 2006-04-12 2011-11-01 Boston Scientific Scimed, Inc. Endoprosthesis having a fiber meshwork disposed thereon
US8815275B2 (en) 2006-06-28 2014-08-26 Boston Scientific Scimed, Inc. Coatings for medical devices comprising a therapeutic agent and a metallic material
CA2655793A1 (en) 2006-06-29 2008-01-03 Boston Scientific Limited Medical devices with selective coating
JP2009545407A (ja) 2006-08-02 2009-12-24 ボストン サイエンティフィック サイムド，インコーポレイテッド 三次元分解制御を備えたエンドプロテーゼ
JP2010503469A (ja) 2006-09-14 2010-02-04 ボストン サイエンティフィック リミテッド 薬物溶出性皮膜を有する医療デバイス
WO2008034066A1 (en) 2006-09-15 2008-03-20 Boston Scientific Limited Bioerodible endoprostheses and methods of making the same
WO2008034013A2 (en) 2006-09-15 2008-03-20 Boston Scientific Limited Medical devices and methods of making the same
DE602007011114D1 (de) 2006-09-15 2011-01-20 Boston Scient Scimed Inc Biologisch erodierbare endoprothese mit biostabilen anorganischen schichten
JP2010503489A (ja) 2006-09-15 2010-02-04 ボストン サイエンティフィック リミテッド 生体内分解性内部人工器官およびその製造方法
WO2008036548A2 (en) 2006-09-18 2008-03-27 Boston Scientific Limited Endoprostheses
US7951191B2 (en) 2006-10-10 2011-05-31 Boston Scientific Scimed, Inc. Bifurcated stent with entire circumferential petal
US7981150B2 (en) 2006-11-09 2011-07-19 Boston Scientific Scimed, Inc. Endoprosthesis with coatings
US7842082B2 (en) 2006-11-16 2010-11-30 Boston Scientific Scimed, Inc. Bifurcated stent
US20090112197A1 (en) * 2007-10-30 2009-04-30 Searete Llc Devices configured to facilitate release of nitric oxide
ES2506144T3 (es) 2006-12-28 2014-10-13 Boston Scientific Limited Endoprótesis bioerosionables y procedimiento de fabricación de las mismas
US7758635B2 (en) 2007-02-13 2010-07-20 Boston Scientific Scimed, Inc. Medical device including cylindrical micelles
US8431149B2 (en) 2007-03-01 2013-04-30 Boston Scientific Scimed, Inc. Coated medical devices for abluminal drug delivery
US8070797B2 (en) 2007-03-01 2011-12-06 Boston Scientific Scimed, Inc. Medical device with a porous surface for delivery of a therapeutic agent
US9220837B2 (en) 2007-03-19 2015-12-29 Insuline Medical Ltd. Method and device for drug delivery
WO2009081262A1 (en) 2007-12-18 2009-07-02 Insuline Medical Ltd. Drug delivery device with sensor for closed-loop operation
US8622991B2 (en) 2007-03-19 2014-01-07 Insuline Medical Ltd. Method and device for drug delivery
US8067054B2 (en) 2007-04-05 2011-11-29 Boston Scientific Scimed, Inc. Stents with ceramic drug reservoir layer and methods of making and using the same
US7976915B2 (en) 2007-05-23 2011-07-12 Boston Scientific Scimed, Inc. Endoprosthesis with select ceramic morphology
US7942926B2 (en) 2007-07-11 2011-05-17 Boston Scientific Scimed, Inc. Endoprosthesis coating
US8002823B2 (en) 2007-07-11 2011-08-23 Boston Scientific Scimed, Inc. Endoprosthesis coating
WO2009012353A2 (en) 2007-07-19 2009-01-22 Boston Scientific Limited Endoprosthesis having a non-fouling surface
US8815273B2 (en) 2007-07-27 2014-08-26 Boston Scientific Scimed, Inc. Drug eluting medical devices having porous layers
US7931683B2 (en) 2007-07-27 2011-04-26 Boston Scientific Scimed, Inc. Articles having ceramic coated surfaces
WO2009018340A2 (en) 2007-07-31 2009-02-05 Boston Scientific Scimed, Inc. Medical device coating by laser cladding
JP2010535541A (ja) 2007-08-03 2010-11-25 ボストン サイエンティフィック リミテッド 広い表面積を有する医療器具用のコーティング
US7959669B2 (en) 2007-09-12 2011-06-14 Boston Scientific Scimed, Inc. Bifurcated stent with open ended side branch support
US8052745B2 (en) 2007-09-13 2011-11-08 Boston Scientific Scimed, Inc. Endoprosthesis
US8877508B2 (en) 2007-10-30 2014-11-04 The Invention Science Fund I, Llc Devices and systems that deliver nitric oxide
US20110182970A1 (en) * 2007-10-30 2011-07-28 Hyde Roderick A Nitric oxide sensors and systems
US10080823B2 (en) 2007-10-30 2018-09-25 Gearbox Llc Substrates for nitric oxide releasing devices
US8980332B2 (en) 2007-10-30 2015-03-17 The Invention Science Fund I, Llc Methods and systems for use of photolyzable nitric oxide donors
US8216632B2 (en) 2007-11-02 2012-07-10 Boston Scientific Scimed, Inc. Endoprosthesis coating
US7938855B2 (en) 2007-11-02 2011-05-10 Boston Scientific Scimed, Inc. Deformable underlayer for stent
US8029554B2 (en) 2007-11-02 2011-10-04 Boston Scientific Scimed, Inc. Stent with embedded material
US7833266B2 (en) 2007-11-28 2010-11-16 Boston Scientific Scimed, Inc. Bifurcated stent with drug wells for specific ostial, carina, and side branch treatment
US8277501B2 (en) 2007-12-21 2012-10-02 Boston Scientific Scimed, Inc. Bi-stable bifurcated stent petal geometry
EP2271380B1 (de) 2008-04-22 2013-03-20 Boston Scientific Scimed, Inc. Medizinprodukte mit einer beschichtung aus anorganischem material
WO2009132176A2 (en) 2008-04-24 2009-10-29 Boston Scientific Scimed, Inc. Medical devices having inorganic particle layers
US7998192B2 (en) 2008-05-09 2011-08-16 Boston Scientific Scimed, Inc. Endoprostheses
US8932340B2 (en) 2008-05-29 2015-01-13 Boston Scientific Scimed, Inc. Bifurcated stent and delivery system
US8652506B2 (en) * 2008-06-05 2014-02-18 Boston Scientific Scimed, Inc. Bio-degradable block co-polymers for controlled release
US8236046B2 (en) 2008-06-10 2012-08-07 Boston Scientific Scimed, Inc. Bioerodible endoprosthesis
EP2303350A2 (de) 2008-06-18 2011-04-06 Boston Scientific Scimed, Inc. Endoprothesen-beschichtung
US7951193B2 (en) 2008-07-23 2011-05-31 Boston Scientific Scimed, Inc. Drug-eluting stent
US7985252B2 (en) 2008-07-30 2011-07-26 Boston Scientific Scimed, Inc. Bioerodible endoprosthesis
WO2010014690A2 (en) * 2008-07-31 2010-02-04 Boston Scientific Scimed, Inc. Medical devices for therapeutic agent delivery
US8382824B2 (en) 2008-10-03 2013-02-26 Boston Scientific Scimed, Inc. Medical implant having NANO-crystal grains with barrier layers of metal nitrides or fluorides
CN102245137A (zh) 2008-11-07 2011-11-16 茵苏莱恩医药有限公司 用于药物递送的装置和方法
US20100131001A1 (en) * 2008-11-24 2010-05-27 Medtronic Vascular, Inc. Targeted Drug Delivery for Aneurysm Treatment
US8231980B2 (en) 2008-12-03 2012-07-31 Boston Scientific Scimed, Inc. Medical implants including iridium oxide
EP2403546A2 (de) 2009-03-02 2012-01-11 Boston Scientific Scimed, Inc. Selbstpufferende medizinische implantate
US8071156B2 (en) 2009-03-04 2011-12-06 Boston Scientific Scimed, Inc. Endoprostheses
US8287937B2 (en) 2009-04-24 2012-10-16 Boston Scientific Scimed, Inc. Endoprosthese
US8668732B2 (en) 2010-03-23 2014-03-11 Boston Scientific Scimed, Inc. Surface treated bioerodible metal endoprostheses
US9662509B2 (en) 2013-05-23 2017-05-30 Cook Medical Technologies Llc Intraluminal activation system and method of activating an inactive agent
CN110584851A (zh) * 2019-09-21 2019-12-20 山东百多安医疗器械有限公司 一种超声控释刻槽可降解微球载药支架及其制备方法

Family Cites Families (97)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6037735B2 (ja) * 1978-10-18 1985-08-28 住友電気工業株式会社 人工血管
US4989601A (en) * 1988-05-02 1991-02-05 Medical Engineering & Development Institute, Inc. Method, apparatus, and substance for treating tissue having neoplastic cells
US5290271A (en) * 1990-05-14 1994-03-01 Jernberg Gary R Surgical implant and method for controlled release of chemotherapeutic agents
AU1579092A (en) * 1991-02-27 1992-10-06 Nova Pharmaceutical Corporation Anti-infective and anti-inflammatory releasing systems for medical devices
US5811447A (en) * 1993-01-28 1998-09-22 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US6515009B1 (en) * 1991-09-27 2003-02-04 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US5500013A (en) * 1991-10-04 1996-03-19 Scimed Life Systems, Inc. Biodegradable drug delivery vascular stent
US5516781A (en) * 1992-01-09 1996-05-14 American Home Products Corporation Method of treating restenosis with rapamycin
US5383928A (en) * 1992-06-10 1995-01-24 Emory University Stent sheath for local drug delivery
DE4222380A1 (de) * 1992-07-08 1994-01-13 Ernst Peter Prof Dr M Strecker In den Körper eines Patienten perkutan implantierbare Endoprothese
US5419760A (en) * 1993-01-08 1995-05-30 Pdt Systems, Inc. Medicament dispensing stent for prevention of restenosis of a blood vessel
US5595722A (en) * 1993-01-28 1997-01-21 Neorx Corporation Method for identifying an agent which increases TGF-beta levels
US5981568A (en) * 1993-01-28 1999-11-09 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US5464650A (en) * 1993-04-26 1995-11-07 Medtronic, Inc. Intravascular stent and method
CA2162586C (en) * 1993-05-13 2006-01-03 David J. Grainger Prevention and treatment of pathologies associated with abnormally proliferative smooth muscle cells
CN100998869A (zh) * 1993-07-19 2007-07-18 血管技术药物公司 抗血管生长组合物及使用方法
US5994341A (en) * 1993-07-19 1999-11-30 Angiogenesis Technologies, Inc. Anti-angiogenic Compositions and methods for the treatment of arthritis
US20030203976A1 (en) * 1993-07-19 2003-10-30 William L. Hunter Anti-angiogenic compositions and methods of use
EP0711158B2 (de) * 1993-07-29 2008-07-23 THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES Verfahren zur behandlung atherosklerose oder restenose mit hilfe eines mikrotubulusstabilisators
US5380299A (en) * 1993-08-30 1995-01-10 Med Institute, Inc. Thrombolytic treated intravascular medical device
US5891108A (en) * 1994-09-12 1999-04-06 Cordis Corporation Drug delivery stent
US5707385A (en) * 1994-11-16 1998-01-13 Advanced Cardiovascular Systems, Inc. Drug loaded elastic membrane and method for delivery
US5605696A (en) * 1995-03-30 1997-02-25 Advanced Cardiovascular Systems, Inc. Drug loaded polymeric material and method of manufacture
US5837313A (en) * 1995-04-19 1998-11-17 Schneider (Usa) Inc Drug release stent coating process
AU716005B2 (en) * 1995-06-07 2000-02-17 Cook Medical Technologies Llc Implantable medical device
US7611533B2 (en) * 1995-06-07 2009-11-03 Cook Incorporated Coated implantable medical device
US5609629A (en) * 1995-06-07 1997-03-11 Med Institute, Inc. Coated implantable medical device
US6774278B1 (en) * 1995-06-07 2004-08-10 Cook Incorporated Coated implantable medical device
US5713949A (en) * 1996-08-06 1998-02-03 Jayaraman; Swaminathan Microporous covered stents and method of coating
US6783543B2 (en) * 2000-06-05 2004-08-31 Scimed Life Systems, Inc. Intravascular stent with increasing coating retaining capacity
US6174326B1 (en) * 1996-09-25 2001-01-16 Terumo Kabushiki Kaisha Radiopaque, antithrombogenic stent and method for its production
US6033433A (en) * 1997-04-25 2000-03-07 Scimed Life Systems, Inc. Stent configurations including spirals
US7208011B2 (en) * 2001-08-20 2007-04-24 Conor Medsystems, Inc. Implantable medical device with drug filled holes
US6241762B1 (en) * 1998-03-30 2001-06-05 Conor Medsystems, Inc. Expandable medical device with ductile hinges
US7208010B2 (en) * 2000-10-16 2007-04-24 Conor Medsystems, Inc. Expandable medical device for delivery of beneficial agent
US6206916B1 (en) * 1998-04-15 2001-03-27 Joseph G. Furst Coated intraluminal graft
US6206914B1 (en) * 1998-04-30 2001-03-27 Medtronic, Inc. Implantable system with drug-eluting cells for on-demand local drug delivery
US6423345B2 (en) * 1998-04-30 2002-07-23 Acusphere, Inc. Matrices formed of polymer and hydrophobic compounds for use in drug delivery
US20020038146A1 (en) * 1998-07-29 2002-03-28 Ulf Harry Expandable stent with relief cuts for carrying medicines and other materials
JP4898991B2 (ja) * 1998-08-20 2012-03-21 クック メディカル テクノロジーズ エルエルシー 被覆付植込式医療装置
US7662409B2 (en) * 1998-09-25 2010-02-16 Gel-Del Technologies, Inc. Protein matrix materials, devices and methods of making and using thereof
US6206915B1 (en) * 1998-09-29 2001-03-27 Medtronic Ave, Inc. Drug storing and metering stent
US6293967B1 (en) * 1998-10-29 2001-09-25 Conor Medsystems, Inc. Expandable medical device with ductile hinges
US6528121B2 (en) * 1998-11-19 2003-03-04 Dow Corning Toray Silicone Co., Ltd. Aqueous treatment agent for wiping paper
US6063101A (en) * 1998-11-20 2000-05-16 Precision Vascular Systems, Inc. Stent apparatus and method
PT1013647E (pt) * 1998-12-21 2003-04-30 Lonza Ag Processo de preparacao de n-(amino-4,6-di-halogenopirimidina)-formamidas
US6530950B1 (en) * 1999-01-12 2003-03-11 Quanam Medical Corporation Intraluminal stent having coaxial polymer member
US6290673B1 (en) * 1999-05-20 2001-09-18 Conor Medsystems, Inc. Expandable medical device delivery system and method
US6503954B1 (en) * 2000-03-31 2003-01-07 Advanced Cardiovascular Systems, Inc. Biocompatible carrier containing actinomycin D and a method of forming the same
US6713119B2 (en) * 1999-09-03 2004-03-30 Advanced Cardiovascular Systems, Inc. Biocompatible coating for a prosthesis and a method of forming the same
US6379381B1 (en) * 1999-09-03 2002-04-30 Advanced Cardiovascular Systems, Inc. Porous prosthesis and a method of depositing substances into the pores
US6682545B1 (en) * 1999-10-06 2004-01-27 The Penn State Research Foundation System and device for preventing restenosis in body vessels
US6491666B1 (en) * 1999-11-17 2002-12-10 Microchips, Inc. Microfabricated devices for the delivery of molecules into a carrier fluid
WO2001064344A2 (en) * 2000-03-02 2001-09-07 Microchips, Inc. Microfabricated devices for the storage and selective exposure of chemicals and devices
EP1132058A1 (de) * 2000-03-06 2001-09-12 Advanced Laser Applications Holding S.A. Intravaskuläre Prothese
US20020007215A1 (en) * 2000-05-19 2002-01-17 Robert Falotico Drug/drug delivery systems for the prevention and treatment of vascular disease
US20020007214A1 (en) * 2000-05-19 2002-01-17 Robert Falotico Drug/drug delivery systems for the prevention and treatment of vascular disease
US20020005206A1 (en) * 2000-05-19 2002-01-17 Robert Falotico Antiproliferative drug and delivery device
US20020007213A1 (en) * 2000-05-19 2002-01-17 Robert Falotico Drug/drug delivery systems for the prevention and treatment of vascular disease
US6776796B2 (en) * 2000-05-12 2004-08-17 Cordis Corportation Antiinflammatory drug and delivery device
US6673385B1 (en) * 2000-05-31 2004-01-06 Advanced Cardiovascular Systems, Inc. Methods for polymeric coatings stents
US6723373B1 (en) * 2000-06-16 2004-04-20 Cordis Corporation Device and process for coating stents
US6555157B1 (en) * 2000-07-25 2003-04-29 Advanced Cardiovascular Systems, Inc. Method for coating an implantable device and system for performing the method
US6716444B1 (en) * 2000-09-28 2004-04-06 Advanced Cardiovascular Systems, Inc. Barriers for polymer-coated implantable medical devices and methods for making the same
AU9463401A (en) * 2000-10-16 2002-04-29 Conor Medsystems Inc Expandable medical device for delivery of beneficial agent
US6506437B1 (en) * 2000-10-17 2003-01-14 Advanced Cardiovascular Systems, Inc. Methods of coating an implantable device having depots formed in a surface thereof
US10398830B2 (en) * 2000-11-17 2019-09-03 Vactronix Scientific, Llc Device for in vivo delivery of bioactive agents and method of manufacture thereof
WO2002059261A2 (en) * 2000-12-07 2002-08-01 The Medstar Research Institute Inhibition of restenosis using a dna-coated stent
US6545097B2 (en) * 2000-12-12 2003-04-08 Scimed Life Systems, Inc. Drug delivery compositions and medical devices containing block copolymer
US20030033007A1 (en) * 2000-12-22 2003-02-13 Avantec Vascular Corporation Methods and devices for delivery of therapeutic capable agents with variable release profile
US20020082679A1 (en) * 2000-12-22 2002-06-27 Avantec Vascular Corporation Delivery or therapeutic capable agents
EP1227449A1 (de) * 2001-01-30 2002-07-31 Siemens Aktiengesellschaft Abrechnungsverfahren für multimediale Netze
US20050278014A9 (en) * 2001-03-07 2005-12-15 Wolfgang Daum Stent and method for drug delivery from stents
US20030004141A1 (en) * 2001-03-08 2003-01-02 Brown David L. Medical devices, compositions and methods for treating vulnerable plaque
US6712845B2 (en) * 2001-04-24 2004-03-30 Advanced Cardiovascular Systems, Inc. Coating for a stent and a method of forming the same
US7493162B2 (en) * 2001-06-15 2009-02-17 Cardiac Pacemakers, Inc. Pulmonary vein stent for treating atrial fibrillation
US6682771B2 (en) * 2001-07-02 2004-01-27 Scimed Life Systems, Inc. Coating dispensing system and method using a solenoid head for coating medical devices
US6676987B2 (en) * 2001-07-02 2004-01-13 Scimed Life Systems, Inc. Coating a medical appliance with a bubble jet printing head
US20030050687A1 (en) * 2001-07-03 2003-03-13 Schwade Nathan D. Biocompatible stents and method of deployment
ATE330564T1 (de) * 2001-07-20 2006-07-15 Sorin Biomedica Cardio Srl Stent
US7056338B2 (en) * 2003-03-28 2006-06-06 Conor Medsystems, Inc. Therapeutic agent delivery device with controlled therapeutic agent release rates
US7195640B2 (en) * 2001-09-25 2007-03-27 Cordis Corporation Coated medical devices for the treatment of vulnerable plaque
DE10150995A1 (de) * 2001-10-08 2003-04-10 Biotronik Mess & Therapieg Implantat mit proliferationshemmender Substanz
US20030077312A1 (en) * 2001-10-22 2003-04-24 Ascher Schmulewicz Coated intraluminal stents and reduction of restenosis using same
US6939376B2 (en) * 2001-11-05 2005-09-06 Sun Biomedical, Ltd. Drug-delivery endovascular stent and method for treating restenosis
US6743463B2 (en) * 2002-03-28 2004-06-01 Scimed Life Systems, Inc. Method for spray-coating a medical device having a tubular wall such as a stent
US6702850B1 (en) * 2002-09-30 2004-03-09 Mediplex Corporation Korea Multi-coated drug-eluting stent for antithrombosis and antirestenosis
CN1714085A (zh) * 2002-11-15 2005-12-28 诺瓦提斯公司 药物递送系统
US20050079199A1 (en) * 2003-02-18 2005-04-14 Medtronic, Inc. Porous coatings for drug release from medical devices
US8088404B2 (en) * 2003-03-20 2012-01-03 Medtronic Vasular, Inc. Biocompatible controlled release coatings for medical devices and related methods
US20050049693A1 (en) * 2003-08-25 2005-03-03 Medtronic Vascular Inc. Medical devices and compositions for delivering biophosphonates to anatomical sites at risk for vascular disease
US20050055078A1 (en) * 2003-09-04 2005-03-10 Medtronic Vascular, Inc. Stent with outer slough coating
US20050060020A1 (en) * 2003-09-17 2005-03-17 Scimed Life Systems, Inc. Covered stent with biologically active material
US7060319B2 (en) * 2003-09-24 2006-06-13 Boston Scientific Scimed, Inc. method for using an ultrasonic nozzle to coat a medical appliance
US8801692B2 (en) * 2003-09-24 2014-08-12 Medtronic Vascular, Inc. Gradient coated stent and method of fabrication
US7055237B2 (en) * 2003-09-29 2006-06-06 Medtronic Vascular, Inc. Method of forming a drug eluting stent
US20060017834A1 (en) * 2004-07-23 2006-01-26 Konica Minolta Opto, Inc. Imaging optical system and imaging lens device

Also Published As

Publication number Publication date
CA2519717A1 (en) 2004-10-14
ATE439887T1 (de) 2009-09-15
AU2004226328B2 (en) 2010-03-04
DE602004022726D1 (de) 2009-10-01
ATE464863T1 (de) 2010-05-15
EP1905477A1 (de) 2008-04-02
EP1608426B1 (de) 2010-04-21
US20040202692A1 (en) 2004-10-14
AU2004226328A1 (en) 2004-10-14
WO2004087251A1 (en) 2004-10-14
EP1905477B1 (de) 2009-08-19
EP1608426A1 (de) 2005-12-28
JP2006523132A (ja) 2006-10-12

Similar Documents

Publication Publication Date Title
DE602004026701D1 (de) Implantierbares medizinprodukt zur selektiven modulation der abgabe von mitteln in situ
ATE358505T1 (de) Beschichtete endovaskuläre vorrichtung
ATE322270T1 (de) Arzneimittel auf basis von gestagenen zur dermalen anwendung enthaltend ascorbinsäure sowie deren salze
DE602005026078D1 (de) Verwendung von Antioxidantien zur Verhinderung von Oxidation und zur Reduzierung von Wirkstoffzersetzung in wirkstoffhaltigen medizinischen Artikeln
NO20034684L (no) Mikroprojeksjonsanordning med belegg inneholdende et fordelaktig middel
BRPI0511609A (pt) sistema de alarme de estado múltiplo para uma bomba médica
MX2009003504A (es) Dispositivo para suministro local y/o regional que utiliza formulaciones liquidas de agentes terapeuticos.
PT737066E (pt) Dispositivo transdermico contendo polivinilpirrolidona como potenciador de solubilidade
DE60308256D1 (de) Beschichtetes medizinsches Implantat zur Behandlung von Gefässerkrankungen
DE60117043D1 (de) Behandlung von mukositis
DE602005011653D1 (de) Medizinprodukt mit gewebeabhängiger arzneimittelelution
BRPI0411924A8 (pt) Métodos e dispositivos para oclusão de lúmens de corpo e/ou para fornecimento de agentes terapêuticos
DE60219607D1 (de) Flexible mikrochip-vorrichtungen zur ophthalmologischen und anderen applikation
DE69925936D1 (de) Vorrichtung zur lokalen verabreichung einer arznei in einer körperhöhle
ATE264672T1 (de) Vorrichtung und verwendung zur steigerung der transdermalen permeation von arzneistoffen
BR0110594A (pt) Sistema de monitoramento hospitalar para monitorar corpo de equipe do hospital, e, método de controlar dispositivos em uma localização de paciente
SE9401406L (sv) Farmaceutiska produkter för att bota tumörsjukdomar samt förfarande för framställning av desamma
DE60324427D1 (de) Verfahren zur modulation der tubulindeacetylase-aktivität
BR0116862A (pt) Medicamento, métodos para tratar um paciente com osteonecrose e/ou osteocondrite dissecans, para prevenir a osteonecrose e/ou osteocondrite dissecans em um paciente em risco de cada uma das ditas doenças, uso de um medicamento, e, método para prevenir a destruição da cartilagem ou condrólise associadas com osteonecrose e/ou osteocondrite dissecans
BRPI0411032A (pt) composição adesiva hidrófila, artigo médico, método para a fabricação da composição adesiva, e, dispositivo de administração transdérmica
WO2003062273A3 (en) Modulator of the notch signalling pathway and use thereof in medical treatment
DE60112777D1 (de) Beschichtete medizinische geräte und verfahren zur sterilisation
ATE368455T1 (de) Verwendung von (+)-tramadol, o-demethyltramadol, o-desmethyl-n-mono-desmethyl-tramadol zur therapie der harninkontinenz
SE0102147D0 (sv) New methods
ATE281159T1 (de) Verwendung von aminosäure zur herstellung von arzneimitteln zur behandlung von insulinresistenz

Legal Events

Date Code Title Description
8327 Change in the person/name/address of the patent owner

Owner name: INNOVATIONAL HOLDINGS LLC, NEW BRUNSWICK, N.J., US

8364 No opposition during term of opposition