DE602004027770D1 - Zusammensetzungen aus orthogonalen Lysyl-TRNA- und Aminoacyl-TRNA-Synthetasepaaren und deren Verwendung - Google Patents

Zusammensetzungen aus orthogonalen Lysyl-TRNA- und Aminoacyl-TRNA-Synthetasepaaren und deren Verwendung

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Publication number
DE602004027770D1
DE602004027770D1 DE602004027770T DE602004027770T DE602004027770D1 DE 602004027770 D1 DE602004027770 D1 DE 602004027770D1 DE 602004027770 T DE602004027770 T DE 602004027770T DE 602004027770 T DE602004027770 T DE 602004027770T DE 602004027770 D1 DE602004027770 D1 DE 602004027770D1
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Prior art keywords
orthogonal
compositions
trna
lysyl
aminoacyl
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Inventor
Christopher J Anderson
Ning Wu
Stephen Santoro
Peter G Schultz
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Scripps Research Institute
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Scripps Research Institute
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/93—Ligases (6)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Saccharide Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE602004027770T 2003-07-07 2004-07-07 Zusammensetzungen aus orthogonalen Lysyl-TRNA- und Aminoacyl-TRNA-Synthetasepaaren und deren Verwendung Active DE602004027770D1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US48545103P 2003-07-07 2003-07-07
US52881503P 2003-12-10 2003-12-10
US53714904P 2004-01-15 2004-01-15

Publications (1)

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DE602004027770D1 true DE602004027770D1 (de) 2010-07-29

Family

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Family Applications (2)

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DE602004011789T Active DE602004011789T2 (de) 2003-07-07 2004-07-07 Zusammensetzungen der orthogonalen Lysyl-tRNA und Aminoacyl-tRNA Synthetase Paaren und ihre Verwendungen
DE602004027770T Active DE602004027770D1 (de) 2003-07-07 2004-07-07 Zusammensetzungen aus orthogonalen Lysyl-TRNA- und Aminoacyl-TRNA-Synthetasepaaren und deren Verwendung

Family Applications Before (1)

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DE602004011789T Active DE602004011789T2 (de) 2003-07-07 2004-07-07 Zusammensetzungen der orthogonalen Lysyl-tRNA und Aminoacyl-tRNA Synthetase Paaren und ihre Verwendungen

Country Status (14)

Country Link
US (4) US7638297B2 (de)
EP (2) EP1666604B1 (de)
JP (2) JP5192150B2 (de)
CN (1) CN101076598B (de)
AT (2) ATE471385T1 (de)
AU (1) AU2004267359B2 (de)
BR (1) BRPI0412272A (de)
CA (1) CA2531146A1 (de)
DE (2) DE602004011789T2 (de)
ES (1) ES2301099T3 (de)
MX (1) MXPA06000242A (de)
PT (2) PT1666604E (de)
SI (1) SI1666604T1 (de)
WO (1) WO2005019415A2 (de)

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