DE60232468D1 - Ente und damit zusammenhängende verfahren - Google Patents

Ente und damit zusammenhängende verfahren

Info

Publication number
DE60232468D1
DE60232468D1 DE60232468T DE60232468T DE60232468D1 DE 60232468 D1 DE60232468 D1 DE 60232468D1 DE 60232468 T DE60232468 T DE 60232468T DE 60232468 T DE60232468 T DE 60232468T DE 60232468 D1 DE60232468 D1 DE 60232468D1
Authority
DE
Germany
Prior art keywords
separation
duck
associated methods
channel
porous matrix
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60232468T
Other languages
English (en)
Inventor
Richard N Zare
Maria T Dulay
Joselito P Quirino
Bryson D Bennett
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
R UNIVERSITY
Original Assignee
R UNIVERSITY
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/124,654 external-priority patent/US6875348B2/en
Application filed by R UNIVERSITY filed Critical R UNIVERSITY
Application granted granted Critical
Publication of DE60232468D1 publication Critical patent/DE60232468D1/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/281Sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J20/286Phases chemically bonded to a substrate, e.g. to silica or to polymers
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/281Sorbents specially adapted for preparative, analytical or investigative chromatography
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30Processes for preparing, regenerating, or reactivating
    • B01J20/32Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3202Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the carrier, support or substrate used for impregnation or coating
    • B01J20/3206Organic carriers, supports or substrates
    • B01J20/3208Polymeric carriers, supports or substrates
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30Processes for preparing, regenerating, or reactivating
    • B01J20/32Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3231Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
    • B01J20/3242Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
    • B01J20/3244Non-macromolecular compounds
    • B01J20/3246Non-macromolecular compounds having a well defined chemical structure
    • B01J20/3257Non-macromolecular compounds having a well defined chemical structure the functional group or the linking, spacer or anchoring group as a whole comprising at least one of the heteroatoms nitrogen, oxygen or sulfur together with at least one silicon atom, these atoms not being part of the carrier as such
    • B01J20/3259Non-macromolecular compounds having a well defined chemical structure the functional group or the linking, spacer or anchoring group as a whole comprising at least one of the heteroatoms nitrogen, oxygen or sulfur together with at least one silicon atom, these atoms not being part of the carrier as such comprising at least two different types of heteroatoms selected from nitrogen, oxygen or sulfur with at least one silicon atom
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2220/00Aspects relating to sorbent materials
    • B01J2220/50Aspects relating to the use of sorbent or filter aid materials
    • B01J2220/54Sorbents specially adapted for analytical or investigative chromatography
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2220/00Aspects relating to sorbent materials
    • B01J2220/80Aspects related to sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J2220/86Sorbents applied to inner surfaces of columns or capillaries
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/50Conditioning of the sorbent material or stationary liquid
    • G01N30/52Physical parameters
    • G01N2030/524Physical parameters structural properties
    • G01N2030/528Monolithic sorbent material
DE60232468T 2001-08-13 2002-08-13 Ente und damit zusammenhängende verfahren Expired - Fee Related DE60232468D1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/929,275 US6866785B2 (en) 2001-08-13 2001-08-13 Photopolymerized sol-gel column and associated methods
US10/124,654 US6875348B2 (en) 2000-02-18 2002-04-16 Separation column having a photopolymerized sol-gel component and associated methods
PCT/US2002/025757 WO2003016859A2 (en) 2001-08-13 2002-08-13 Separation column having a photopolymerized sol-gel component and associated methods

Publications (1)

Publication Number Publication Date
DE60232468D1 true DE60232468D1 (de) 2009-07-09

Family

ID=25457591

Family Applications (2)

Application Number Title Priority Date Filing Date
DE60236165T Expired - Lifetime DE60236165D1 (de) 2001-08-13 2002-08-13 Photopolymerisierte sol-gel-säule mit gebundener phase und zugehörige verfahren
DE60232468T Expired - Fee Related DE60232468D1 (de) 2001-08-13 2002-08-13 Ente und damit zusammenhängende verfahren

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE60236165T Expired - Lifetime DE60236165D1 (de) 2001-08-13 2002-08-13 Photopolymerisierte sol-gel-säule mit gebundener phase und zugehörige verfahren

Country Status (5)

Country Link
US (2) US6866785B2 (de)
AT (2) ATE465795T1 (de)
AU (1) AU2002326633A1 (de)
DE (2) DE60236165D1 (de)
ES (1) ES2345328T3 (de)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6833242B2 (en) * 1997-09-23 2004-12-21 California Institute Of Technology Methods for detecting and sorting polynucleotides based on size
AU2001273057A1 (en) * 2000-06-27 2002-01-08 Fluidigm Corporation A microfluidic design automation method and system
AU2001290879A1 (en) 2000-09-15 2002-03-26 California Institute Of Technology Microfabricated crossflow devices and methods
US7232109B2 (en) * 2000-11-06 2007-06-19 California Institute Of Technology Electrostatic valves for microfluidic devices
US6960437B2 (en) 2001-04-06 2005-11-01 California Institute Of Technology Nucleic acid amplification utilizing microfluidic devices
US7075162B2 (en) * 2001-08-30 2006-07-11 Fluidigm Corporation Electrostatic/electrostrictive actuation of elastomer structures using compliant electrodes
US7192629B2 (en) * 2001-10-11 2007-03-20 California Institute Of Technology Devices utilizing self-assembled gel and method of manufacture
US8440093B1 (en) 2001-10-26 2013-05-14 Fuidigm Corporation Methods and devices for electronic and magnetic sensing of the contents of microfluidic flow channels
CA2467587A1 (en) 2001-11-30 2003-06-12 Fluidigm Corporation Microfluidic device and methods of using same
US7691333B2 (en) 2001-11-30 2010-04-06 Fluidigm Corporation Microfluidic device and methods of using same
US20030164297A1 (en) * 2002-03-04 2003-09-04 Corning Incorporated Electrophoretic inorganic porous material
WO2003085379A2 (en) 2002-04-01 2003-10-16 Fluidigm Corporation Microfluidic particle-analysis systems
US7312085B2 (en) * 2002-04-01 2007-12-25 Fluidigm Corporation Microfluidic particle-analysis systems
EP1535066A2 (de) * 2002-06-24 2005-06-01 Fluidigm Corporation Rezirkulationsfluidnetz und verwendungsverfahren dafür
US20050061745A1 (en) * 2002-06-26 2005-03-24 Teledyne Isco, Inc. Separation system, components of a separation system and methods of making and using them
US6749749B2 (en) * 2002-06-26 2004-06-15 Isco, Inc. Separation system, components of a separation system and methods of making and using them
US7473367B2 (en) * 2002-06-26 2009-01-06 Dionex Corporation Monolithic column
EP1551753A2 (de) 2002-09-25 2005-07-13 California Institute Of Technology Hochintegriertes mikrofluidisches netzwerk
JP5695287B2 (ja) 2002-10-02 2015-04-01 カリフォルニア インスティテュート オブ テクノロジー 微小流体の核酸解析
GB0227424D0 (en) * 2002-11-25 2002-12-31 Univ Warwick Coatings
US7476363B2 (en) * 2003-04-03 2009-01-13 Fluidigm Corporation Microfluidic devices and methods of using same
US20050145496A1 (en) 2003-04-03 2005-07-07 Federico Goodsaid Thermal reaction device and method for using the same
EP2340890B1 (de) * 2003-04-03 2016-10-19 Fluidigm Corporation Verfahren zur Durchführung von Digitaler PCR
US7604965B2 (en) 2003-04-03 2009-10-20 Fluidigm Corporation Thermal reaction device and method for using the same
US8828663B2 (en) * 2005-03-18 2014-09-09 Fluidigm Corporation Thermal reaction device and method for using the same
US20070141325A1 (en) 2003-05-28 2007-06-21 Waters Investments Limited Novel nanocomposites and their application as monolith columns
US7413712B2 (en) * 2003-08-11 2008-08-19 California Institute Of Technology Microfluidic rotary flow reactor matrix
US20050127002A1 (en) * 2003-12-12 2005-06-16 Zare Richard N. Immobilized-enzyme microreactor devices for characterization of biomolecular analytes and associated methods
US7815802B2 (en) 2005-02-28 2010-10-19 University Of Virginia Patent Foundation Grafted photo-polymerized monolithic column
US20070181479A1 (en) * 2005-11-21 2007-08-09 Pentax Corporation Column and method of manufacturing the column
JP4962490B2 (ja) * 2006-03-29 2012-06-27 ダイソー株式会社 修飾シリカゲル及びその利用
EP2105736A1 (de) * 2008-03-28 2009-09-30 Novartis Ag DNA-Analyse mittels Kapillar-Elektrophorese
JP5597191B2 (ja) * 2008-04-08 2014-10-01 ウオーターズ・テクノロジーズ・コーポレイシヨン ナノ粒子含有複合材料およびこのクロマトグラフィーでの使用
WO2009132330A2 (en) * 2008-04-25 2009-10-29 Biotrove, Inc. Separation cartridges and methods for fabrication and use thereof
US9129785B2 (en) 2013-08-01 2015-09-08 The Board Of Trustees Of The Leland Stanford Junior University Metal organic polymer matrices and systems for chemical and biochemical mass spectrometry and methods of use thereof
WO2015160996A1 (en) * 2014-04-15 2015-10-22 University Of Washington Isotachophoretic device and methods
CN112337411B (zh) * 2020-10-13 2023-05-23 烟台大学 一种金属有机凝胶的制备方法及其应用

Family Cites Families (49)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3503712A (en) 1966-05-18 1970-03-31 Research Corp Apparatus for effecting interactions of fluids at extended solid surfaces
US3568840A (en) 1967-12-30 1971-03-09 Mitsubishi Chem Ind Packing materials for gel permeation chromatography
US3757490A (en) 1971-06-07 1973-09-11 Ja Ma Chromatographic adsorbents
US3808125A (en) 1972-08-25 1974-04-30 Phillips Petroleum Co Chromatographic apparatus
US3878092A (en) 1973-03-12 1975-04-15 Phillips Petroleum Co Chromatographic colums
US4293415A (en) 1979-04-27 1981-10-06 Hewlett-Packard Company Silica chromatographic column
US4323439A (en) 1979-12-31 1982-04-06 The Regents Of The University Of California Method and apparatus for dynamic equilibrium electrophoresis
US4790919A (en) 1984-06-28 1988-12-13 E. I. Du Pont De Nemours And Company Process for preparation of electrophoresis gel material
US4617102A (en) 1985-03-21 1986-10-14 Lifecodes Corp. Process and apparatus for purifying and concentrating DNA from crude mixtures containing DNA
US4675300A (en) 1985-09-18 1987-06-23 The Board Of Trustees Of The Leland Stanford Junior University Laser-excitation fluorescence detection electrokinetic separation
US5116495A (en) 1987-09-11 1992-05-26 Ottosensors Corporation Capillary chromatography device
US5202010A (en) 1987-11-25 1993-04-13 Princeton Biochemicals, Inc. Automated capillary electrophoresis apparatus
IL93134A (en) 1990-01-23 1997-11-20 Yissum Res Dev Co Doped sol-gel glasses for obtaining chemical interactions
US5308495A (en) 1990-01-23 1994-05-03 Yissum, Research Development Company Of The Hebrew University Of Jerusalem Chromatography processes using doped sol gel glasses as chromatographic media
US5200150A (en) * 1990-06-14 1993-04-06 Hewlett-Packard Company Preparation of gel-filled separation columns
US5085756A (en) 1990-08-21 1992-02-04 Hewlett-Packard Company Column separation system for electrophoresis with sample pretreatment
US5135627A (en) 1990-10-15 1992-08-04 Soane Technologies, Inc. Mosaic microcolumns, slabs, and separation media for electrophoresis and chromatography
US5340452A (en) 1991-02-01 1994-08-23 Beckman Instruments, Inc. On-column preconcentration of samples in capillary electrophoresis
US5453382A (en) 1991-08-05 1995-09-26 Indiana University Foundation Electrochromatographic preconcentration method
US5116471A (en) 1991-10-04 1992-05-26 Varian Associates, Inc. System and method for improving sample concentration in capillary electrophoresis
JP3168006B2 (ja) 1991-10-21 2001-05-21 コーネル・リサーチ・フアウンデーシヨン・インコーポレーテツド マクロ細孔ポリマー媒体が備わっているカラム
US5552994A (en) * 1992-09-23 1996-09-03 Onkor, Ltd. System for printing social expression cards in response to electronically transmitted orders
US5316680A (en) 1992-10-21 1994-05-31 Cornell Research Foundation, Inc. Multimodal chromatographic separation media and process for using same
US5505831A (en) 1993-01-26 1996-04-09 Bio-Rad Laboratories, Inc. Concentration of biological samples on a microliter scale and analysis by capillary electrophoresis
EP0710219B1 (de) * 1993-07-19 1997-12-10 MERCK PATENT GmbH Anorganisches, poröses material und verfahren zu dessen herstellung
US5423966A (en) 1994-01-25 1995-06-13 Perkin-Elmer Corporation On line ion contaminant removal apparatus and method for capillary electrophoresis
US5653875A (en) 1994-02-04 1997-08-05 Supelco, Inc. Nucleophilic bodies bonded to siloxane and use thereof for separations from sample matrices
SE9402091D0 (sv) 1994-06-14 1994-06-14 Pharmacia Biotech Ab Kromatografikolonn
JP3498865B2 (ja) * 1994-09-26 2004-02-23 本田技研工業株式会社 小型雪上車のステップフロア
US5728457A (en) 1994-09-30 1998-03-17 Cornell Research Foundation, Inc. Porous polymeric material with gradients
US5522994A (en) 1995-02-01 1996-06-04 Cornell Research Foundation, Inc. Single column chromatographic determination of small molecules in mixtures with large molecules
DE29623801U1 (de) 1995-03-03 1999-11-11 Alltech Associates Inc Apparat zur elektrochemischen Modifizierung chromatographischen Materials
US5800692A (en) 1995-04-17 1998-09-01 Mayo Foundation For Medical Education And Research Preseparation processor for use in capillary electrophoresis
US5637135A (en) 1995-06-26 1997-06-10 Capillary Technology Corporation Chromatographic stationary phases and adsorbents from hybrid organic-inorganic sol-gels
US5916427A (en) 1995-11-08 1999-06-29 Kirkpatrick; Francis H Methods and reagents for gel electrophoresis
DE69523610T2 (de) 1995-12-14 2003-04-03 Agilent Technologies Inc Säule für kapillarchromatographische Trennverfahren
US5938919A (en) 1995-12-22 1999-08-17 Phenomenex Fused silica capillary columns protected by flexible shielding
US5667674A (en) 1996-01-11 1997-09-16 Minnesota Mining And Manufacturing Company Adsorption medium and method of preparing same
US5728296A (en) 1996-03-20 1998-03-17 Bio-Rad Laboratories, Inc. Selective recognition of solutes in chromatographic media by artificially created affinity
EP0809108B1 (de) 1996-05-20 2003-09-24 Agilent Technologies, Inc. (a Delaware corporation) Kapillarsäule für chromatographische Trennungen und Verfahren zur Herstellung
US5647979A (en) 1996-06-14 1997-07-15 Bio-Rad Laboratories, Inc. One-step preparation of separation media for reversed-phase chromatography
US5719322A (en) 1996-09-20 1998-02-17 Uop Zeolitic capillary columns for gas chromatography
WO1998058253A1 (de) * 1997-06-18 1998-12-23 Merck Patent Gmbh Verwendung monolithischer sorbentien für präparative chromatographische trennverfahren
US6136187A (en) 1997-12-09 2000-10-24 The Board Of Trustees Of The Leland Stanford Junior University Separation column containing porous matrix and method of packing column
WO1999038006A1 (en) * 1998-01-23 1999-07-29 Merck Patent Gmbh Process for producing inorganic porous material in a capillary
JPH11287791A (ja) * 1998-04-01 1999-10-19 Naohiro Soga キャピラリーカラム
US6210570B1 (en) * 1998-08-21 2001-04-03 Agilent Technologies, Inc. Monolithic silica column
US6428666B1 (en) 1999-02-22 2002-08-06 Sandia National Laboratories Electrokinetic concentration of charged molecules
JP4843845B2 (ja) * 2000-07-03 2011-12-21 トヨタ自動車株式会社 燃料電池システムおよびその制御方法

Also Published As

Publication number Publication date
ES2345328T3 (es) 2010-09-21
US20030062308A1 (en) 2003-04-03
US6884346B2 (en) 2005-04-26
ATE432117T1 (de) 2009-06-15
ATE465795T1 (de) 2010-05-15
AU2002326633A1 (en) 2003-03-03
DE60236165D1 (de) 2010-06-10
US6866785B2 (en) 2005-03-15
US20030062309A1 (en) 2003-04-03

Similar Documents

Publication Publication Date Title
DE60232468D1 (de) Ente und damit zusammenhängende verfahren
WO2003016859A3 (en) Separation column having a photopolymerized sol-gel component and associated methods
SE0202114D0 (sv) Polymer affinity matrix, a method for the production and use thereof
NO996243L (no) Retentatkromatografi og proteinchipsrekker med anvendelse innen biologi og medisin
ATE342508T1 (de) Kapseln, enthaltend feststoffpartikeln von signalerzeugenden organischen substanzen
WO2007065025A3 (en) Method of dna analysis using micro/nanochannel
AU6380001A (en) Porous ferro- or ferrimagnetic glass particles for isolating molecules
ATE405841T1 (de) In-vitro-verfahren zum gleichzeitigen nachweisen und identifizieren von antibiotika unterschiedlicher klassen sowie entsprechender diagnostischer kit
ATE441669T1 (de) Stabile lagerung von protein und stabile lagerung von nukleinsäure in wiedergewinnbarer form
WO2004036189A3 (en) Methods for separating molecules
ATE469911T1 (de) Isolierte nukleinsäuremoleküle die t-zellen induzierbare faktoren kodieren (tif), kodierte proteine und ihre anwendung
WO2006015368A3 (en) Molecules with effects on cellular development and function
DE60328001D1 (de) Elektrochemische nachweissystemen
WO2006045103A3 (en) Device and method for removing heavy metals from contaminated samples with membranes comprising purified metallothionein
WO2006008143A3 (en) Apparatus components and methods of using apparatus components to detect the presence of an analyte
MD20080029A (en) Static support bed for purification, separation, modification and/or immobilization of target entities and method using thereof
DE602004018504D1 (de) Cucurbituril enthaltendes polymer, stationäre phase und säule damit
CY1115474T1 (el) Χρωματογραφικη μεθοδος
ATE248631T1 (de) Einstufige vorrichtung und verfahren zur konzentration und säuberung biologischer moleküle
ATE358621T1 (de) Sequenzgestell
ES2172801T3 (es) Procedimiento y dispositivo para la purificacion y enriquecimiento de moleculas.
SE0302911D0 (sv) Novel separation matrix
DE69831429D1 (de) Verfahren zur langzeitlagerung von dns-molekülen, und verpackung zur durchführung dieses verfahrens
DE602004005394D1 (de) Medium zur Datenspeicherung, Verfahren dazu sowie die Farbstoffe als solche
DK1476549T3 (da) Fremgangsmåde til konformations-afhængig separering af ikke-cirkulære nukleinsyrer

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee