DE60232747D1 - Handgerät zur transdermalen Verabreichung von Medikamenten und zur Entnahme von Körperflüssigkeiten - Google Patents

Handgerät zur transdermalen Verabreichung von Medikamenten und zur Entnahme von Körperflüssigkeiten

Info

Publication number
DE60232747D1
DE60232747D1 DE60232747T DE60232747T DE60232747D1 DE 60232747 D1 DE60232747 D1 DE 60232747D1 DE 60232747 T DE60232747 T DE 60232747T DE 60232747 T DE60232747 T DE 60232747T DE 60232747 D1 DE60232747 D1 DE 60232747D1
Authority
DE
Germany
Prior art keywords
receiving
electrode
electrical contact
medicaments
removal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60232747T
Other languages
English (en)
Inventor
Zohar Avrahami
Ze Ev Sohn
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
TransPharma Ltd
Original Assignee
TransPharma Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by TransPharma Ltd filed Critical TransPharma Ltd
Application granted granted Critical
Publication of DE60232747D1 publication Critical patent/DE60232747D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/20Applying electric currents by contact electrodes continuous direct currents
    • A61N1/30Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/325Applying electric currents by contact electrodes alternating or intermittent currents for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body
DE60232747T 2001-04-23 2002-04-22 Handgerät zur transdermalen Verabreichung von Medikamenten und zur Entnahme von Körperflüssigkeiten Expired - Lifetime DE60232747D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US09/840,522 US6708060B1 (en) 1998-11-09 2001-04-23 Handheld apparatus and method for transdermal drug delivery and analyte extraction

Publications (1)

Publication Number Publication Date
DE60232747D1 true DE60232747D1 (de) 2009-08-06

Family

ID=25282592

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60232747T Expired - Lifetime DE60232747D1 (de) 2001-04-23 2002-04-22 Handgerät zur transdermalen Verabreichung von Medikamenten und zur Entnahme von Körperflüssigkeiten

Country Status (9)

Country Link
US (2) US6708060B1 (de)
EP (2) EP1502622B1 (de)
JP (1) JP4262985B2 (de)
AT (1) ATE434464T1 (de)
AU (1) AU2002307781B2 (de)
CA (1) CA2445118A1 (de)
DE (1) DE60232747D1 (de)
IL (1) IL158582A0 (de)
WO (1) WO2002085451A2 (de)

Families Citing this family (159)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7537605B2 (en) * 1993-10-04 2009-05-26 Huan-Chen Li Medical device for treating skin itch and rash
US6792306B2 (en) * 2000-03-10 2004-09-14 Biophoretic Therapeutic Systems, Llc Finger-mounted electrokinetic delivery system for self-administration of medicaments and methods therefor
US20030078499A1 (en) * 1999-08-12 2003-04-24 Eppstein Jonathan A. Microporation of tissue for delivery of bioactive agents
USRE44145E1 (en) 2000-07-07 2013-04-09 A.V. Topchiev Institute Of Petrochemical Synthesis Preparation of hydrophilic pressure sensitive adhesives having optimized adhesive properties
US8541021B2 (en) 2001-05-01 2013-09-24 A.V. Topchiev Institute Of Petrochemical Synthesis Hydrogel compositions demonstrating phase separation on contact with aqueous media
US20050113510A1 (en) 2001-05-01 2005-05-26 Feldstein Mikhail M. Method of preparing polymeric adhesive compositions utilizing the mechanism of interaction between the polymer components
ES2587187T3 (es) * 2001-05-01 2016-10-21 A. V. Topchiev Institute Of Petrochemical Synthesis Composición bioadhesiva absorbente de agua bifásica
US20050215727A1 (en) 2001-05-01 2005-09-29 Corium Water-absorbent adhesive compositions and associated methods of manufacture and use
US8840918B2 (en) 2001-05-01 2014-09-23 A. V. Topchiev Institute of Petrochemical Synthesis, Russian Academy of Sciences Hydrogel compositions for tooth whitening
JP4116447B2 (ja) 2001-05-01 2008-07-09 エイ.ブイ.トップチーブ インスティテュート オブ ペトロケミカル シンセシス ヒドロゲル組成物
US8206738B2 (en) 2001-05-01 2012-06-26 Corium International, Inc. Hydrogel compositions with an erodible backing member
DE10151471A1 (de) * 2001-10-18 2003-05-15 Disetronic Licensing Ag Injektionsgerät mit Energiespeicher
CA2478822C (en) 2002-03-11 2016-07-12 Altea Therapeutics Corporation Transdermal drug delivery patch system, method of making same and method of using same
US8116860B2 (en) 2002-03-11 2012-02-14 Altea Therapeutics Corporation Transdermal porator and patch system and method for using same
EP1499255B1 (de) * 2002-04-19 2015-07-22 Syneron Medical Ltd. In der hand gehaltene transdermale arzneimittelabgabe und analytenextraktion
AU2003280136A1 (en) * 2002-06-28 2004-01-19 Alza Corporation A reservoir for use in an electrotransport drug delivery device
IL152573A (en) 2002-10-31 2009-11-18 Transpharma Medical Ltd A system for the transmission through the skin of a medical preparation against vomiting and nausea
US7662404B2 (en) * 2002-10-31 2010-02-16 Transpharma Medical Ltd. Transdermal delivery system for dried particulate or lyophilized peptides and polypeptides
IL152574A (en) 2002-10-31 2009-09-22 Transpharma Medical Ltd A system for passing through the skin of dry items or dried medicines
US8133505B2 (en) * 2002-10-31 2012-03-13 Transpharma Medical Ltd. Transdermal delivery system for dried particulate or lyophilized medications
IL152575A (en) 2002-10-31 2008-12-29 Transpharma Medical Ltd A skin-to-skin transmission system of water-insoluble drugs
US7383084B2 (en) * 2002-10-31 2008-06-03 Transpharma Medical Ltd. Transdermal delivery system for dried particulate or lyophilized medications
JP4381705B2 (ja) * 2003-03-26 2009-12-09 シスメックス株式会社 経皮的分析物抽出システムと分析システムおよび経皮的分析物抽出方法と分析方法
US7137979B2 (en) 2003-05-31 2006-11-21 Tyrell, Inc. Methods and devices for the treatment of skin lesions
US8016810B2 (en) * 2003-06-23 2011-09-13 Transpharma Medical Ltd. Transdermal delivery system for cosmetic agents
US8016811B2 (en) 2003-10-24 2011-09-13 Altea Therapeutics Corporation Method for transdermal delivery of permeant substances
IL159273A0 (en) * 2003-12-09 2004-06-01 Transpharma Medical Ltd Transdermal delivery system for sustained release of polypeptides
IL160033A0 (en) * 2004-01-25 2004-06-20 Transpharma Medical Ltd Transdermal delivery system for polynucleotides
US8658201B2 (en) 2004-01-30 2014-02-25 Corium International, Inc. Rapidly dissolving film for delivery of an active agent
EP1742588B1 (de) * 2004-04-01 2016-10-19 The General Hospital Corporation Gerät für die dermatologische behandlung und gewebeumformung
US8690865B2 (en) * 2004-05-28 2014-04-08 Georgia Tech Research Corporation Methods and devices for thermal treatment
US20070292445A1 (en) * 2004-07-06 2007-12-20 Transpharma Medical Ltd. Delivery system for transdermal immunization
ES2526700T3 (es) * 2004-08-05 2015-01-14 Corium International, Inc. Composición de adhesivo
US20060047281A1 (en) * 2004-09-01 2006-03-02 Syneron Medical Ltd. Method and system for invasive skin treatment
US20060089637A1 (en) 2004-10-14 2006-04-27 Werneth Randell L Ablation catheter
CA2587780A1 (en) * 2004-11-18 2006-05-26 Transpharma Medical Ltd. Combined micro-channel generation and iontophoresis for transdermal delivery of pharmaceutical agents
US8096303B2 (en) 2005-02-08 2012-01-17 Koninklijke Philips Electronics N.V Airway implants and methods and devices for insertion and retrieval
US8371307B2 (en) 2005-02-08 2013-02-12 Koninklijke Philips Electronics N.V. Methods and devices for the treatment of airway obstruction, sleep apnea and snoring
US8836513B2 (en) 2006-04-28 2014-09-16 Proteus Digital Health, Inc. Communication system incorporated in an ingestible product
US8730031B2 (en) 2005-04-28 2014-05-20 Proteus Digital Health, Inc. Communication system using an implantable device
EP3827747A1 (de) * 2005-04-28 2021-06-02 Otsuka Pharmaceutical Co., Ltd. Pharmainformatiksystem
US9198608B2 (en) 2005-04-28 2015-12-01 Proteus Digital Health, Inc. Communication system incorporated in a container
US8802183B2 (en) 2005-04-28 2014-08-12 Proteus Digital Health, Inc. Communication system with enhanced partial power source and method of manufacturing same
US8912908B2 (en) 2005-04-28 2014-12-16 Proteus Digital Health, Inc. Communication system with remote activation
US20070049998A1 (en) * 2005-05-18 2007-03-01 Tyrell, Inc. Treatment device and method for treating skin lesions through application of heat
WO2006131931A2 (en) * 2005-06-10 2006-12-14 Transpharma Medical, Ltd. Patch for transdermal drug delivery
TWI419717B (zh) 2005-06-17 2013-12-21 Altea Therapeutics Corp 滲透傳送系統及其使用方法
US20070009542A1 (en) 2005-07-05 2007-01-11 Galit Levin Method and device for transdermal immunization
US8547248B2 (en) 2005-09-01 2013-10-01 Proteus Digital Health, Inc. Implantable zero-wire communications system
US20070078502A1 (en) * 2005-10-05 2007-04-05 Thermage, Inc. Method and apparatus for estimating a local impedance factor
US7957815B2 (en) * 2005-10-11 2011-06-07 Thermage, Inc. Electrode assembly and handpiece with adjustable system impedance, and methods of operating an energy-based medical system to treat tissue
US8702691B2 (en) * 2005-10-19 2014-04-22 Thermage, Inc. Treatment apparatus and methods for delivering energy at multiple selectable depths in tissue
EP1948221B1 (de) * 2005-11-02 2015-04-08 Syneron Medical Ltd. Pflasterzusammensetzungen mit humanem wachstumshormon
US8022054B2 (en) 2005-11-28 2011-09-20 Marinus Pharmaceuticals Liquid ganaxolone formulations and methods for the making and use thereof
US7634314B2 (en) * 2005-11-30 2009-12-15 Ak Beauty Enterprises, Llc Powered stimulation device
US20070128420A1 (en) * 2005-12-07 2007-06-07 Mariam Maghribi Hybrid composite for biological tissue interface devices
WO2007109194A2 (en) * 2006-03-17 2007-09-27 Bovie Medical Apparatus and method for skin tightening and corrective forming
EP2010276B1 (de) * 2006-04-26 2014-01-22 Covidien LP Mehrfachmodus-mikroporationsvorrichtung
JP2009544338A (ja) * 2006-05-02 2009-12-17 プロテウス バイオメディカル インコーポレイテッド 患者に合わせてカスタマイズした治療レジメン
US20080008978A1 (en) * 2006-05-08 2008-01-10 Tyrell, Inc. Treatment device and method for treating or preventing periodontal disease through application of heat
US20070259316A1 (en) * 2006-05-08 2007-11-08 Tyrell, Inc. Treatment device and method for treating or preventing periodontal disease through application of heat
US8246611B2 (en) * 2006-06-14 2012-08-21 Candela Corporation Treatment of skin by spatial modulation of thermal heating
US8054140B2 (en) 2006-10-17 2011-11-08 Proteus Biomedical, Inc. Low voltage oscillator for medical devices
KR101611240B1 (ko) 2006-10-25 2016-04-11 프로테우스 디지털 헬스, 인코포레이티드 복용 가능한 제어된 활성화 식별자
WO2008063626A2 (en) 2006-11-20 2008-05-29 Proteus Biomedical, Inc. Active signal processing personal health signal receivers
EP2101735A2 (de) 2006-11-28 2009-09-23 Marinus Pharmaceuticals, Inc. Nanoteilchenförmige formulierungen und verfahren zur herstellung und verwendung
WO2008091983A2 (en) * 2007-01-25 2008-07-31 Thermage, Inc. Treatment apparatus and methods for inducing microburn patterns in tissue
MY165532A (en) 2007-02-01 2018-04-02 Proteus Digital Health Inc Ingestible event marker systems
EP2111661B1 (de) 2007-02-14 2017-04-12 Proteus Digital Health, Inc. Körperintegrierte stromquelle mit grossflächiger elektrode
WO2008112577A1 (en) * 2007-03-09 2008-09-18 Proteus Biomedical, Inc. In-body device having a multi-directional transmitter
EP2063771A1 (de) 2007-03-09 2009-06-03 Proteus Biomedical, Inc. Körperintegrierte vorrichtung mit ausfahrbarer antenne
WO2008131072A1 (en) * 2007-04-17 2008-10-30 Transport Pharmaceuticals, Inc. Current density detection and control system and method for an electrokinetic delivery of medicaments
US20080269735A1 (en) * 2007-04-26 2008-10-30 Agustina Vila Echague Optical array for treating biological tissue
US8540632B2 (en) * 2007-05-24 2013-09-24 Proteus Digital Health, Inc. Low profile antenna for in body device
US8216218B2 (en) * 2007-07-10 2012-07-10 Thermage, Inc. Treatment apparatus and methods for delivering high frequency energy across large tissue areas
EP4011289A1 (de) 2007-09-25 2022-06-15 Otsuka Pharmaceutical Co., Ltd. Körperinterne vorrichtung mit virtueller dipol-signal-verstärkung
JP5466161B2 (ja) * 2007-10-09 2014-04-09 トランスファーマ メディカル リミテッド 磁気的なパッチ連結物
WO2009050718A2 (en) * 2007-10-17 2009-04-23 Transpharma Medical Ltd. Dissolution rate verification
US20100293807A1 (en) * 2007-10-29 2010-11-25 Transpharma Medical, Ltd. Vertical patch drying
US20090135886A1 (en) * 2007-11-27 2009-05-28 Proteus Biomedical, Inc. Transbody communication systems employing communication channels
MX2010006062A (es) 2007-12-05 2010-09-14 Syneron Medical Ltd Aplicador desechable de energia electromagnetica y metodo para su uso.
US20090149930A1 (en) * 2007-12-07 2009-06-11 Thermage, Inc. Apparatus and methods for cooling a treatment apparatus configured to non-invasively deliver electromagnetic energy to a patient's tissue
KR101626167B1 (ko) 2008-01-17 2016-05-31 시네론 메디컬 리미티드 개인용 모발 제거 장치 및 그 사용 방법
JP2011509791A (ja) 2008-01-24 2011-03-31 シネロン メディカル リミテッド 脂肪組織治療の機器、装置および方法
JP2011513865A (ja) 2008-03-05 2011-04-28 プロテウス バイオメディカル インコーポレイテッド マルチモード通信の摂取可能なイベントマーカーおよびシステム、ならびにそれを使用する方法
EP2268244B1 (de) 2008-03-31 2018-07-04 Nitto Denko Corporation Durchdringendes abgabesystem und anwendungsverfahren dafür
US8515553B2 (en) * 2008-04-28 2013-08-20 Thermage, Inc. Methods and apparatus for predictively controlling the temperature of a coolant delivered to a treatment device
US8285392B2 (en) * 2008-06-19 2012-10-09 Thermage, Inc. Leakage-resistant tissue treatment apparatus and methods of using such tissue treatment apparatus
US8121704B2 (en) * 2008-06-19 2012-02-21 Thermage, Inc. Leakage-resistant tissue treatment apparatus and methods of using same
WO2010005877A2 (en) 2008-07-08 2010-01-14 Proteus Biomedical, Inc. Ingestible event marker data framework
US9314293B2 (en) * 2008-07-16 2016-04-19 Syneron Medical Ltd RF electrode for aesthetic and body shaping devices and method of using same
US20100017750A1 (en) * 2008-07-16 2010-01-21 Avner Rosenberg User interface
KR101214453B1 (ko) 2008-08-13 2012-12-24 프로테우스 디지털 헬스, 인코포레이티드 복용 가능한 회로
DE102008039844A1 (de) * 2008-08-27 2010-03-04 Fresenius Medical Care Deutschland Gmbh Tastkopf mit wenigstens zwei Elektroden zur Impedanzmessung, Anordnung und Verfahren hierzu
WO2010029552A1 (en) * 2008-09-10 2010-03-18 Transpharma Medical Ltd. Transdermal delivery of oligosaccharides
KR101523807B1 (ko) * 2008-09-21 2015-05-28 시네론 메디컬 리미티드 개인용 피부 치료 장치
AU2009305770A1 (en) * 2008-10-14 2010-04-22 Proteus Digital Health, Inc. Method and system for incorporating physiologic data in a gaming environment
KR101192690B1 (ko) 2008-11-13 2012-10-19 프로테우스 디지털 헬스, 인코포레이티드 섭취 가능한 치료 활성화 시스템, 치료 장치 및 방법
WO2010059527A2 (en) * 2008-11-18 2010-05-27 Proteus Biomedical, Inc. Sensing system, device, and method for therapy modulation
US8357150B2 (en) 2009-07-20 2013-01-22 Syneron Medical Ltd. Method and apparatus for fractional skin treatment
SG172077A1 (en) 2008-12-11 2011-07-28 Proteus Biomedical Inc Evaluation of gastrointestinal function using portable electroviscerography systems and methods of using the same
US9659423B2 (en) 2008-12-15 2017-05-23 Proteus Digital Health, Inc. Personal authentication apparatus system and method
WO2013012869A1 (en) 2011-07-21 2013-01-24 Proteus Digital Health, Inc. Mobile communication device, system, and method
US9439566B2 (en) 2008-12-15 2016-09-13 Proteus Digital Health, Inc. Re-wearable wireless device
TWI503101B (zh) 2008-12-15 2015-10-11 Proteus Digital Health Inc 與身體有關的接收器及其方法
CN102341031A (zh) 2009-01-06 2012-02-01 普罗秋斯生物医学公司 摄取相关的生物反馈和个人化医学治疗方法和系统
EP3395333A1 (de) 2009-01-06 2018-10-31 Proteus Digital Health, Inc. System zur dosierten verabreichung von arzneimitteln
US8784879B2 (en) * 2009-01-14 2014-07-22 Corium International, Inc. Transdermal administration of tamsulosin
US8606366B2 (en) 2009-02-18 2013-12-10 Syneron Medical Ltd. Skin treatment apparatus for personal use and method for using same
US9278230B2 (en) * 2009-02-25 2016-03-08 Syneron Medical Ltd Electrical skin rejuvenation
GB2480965B (en) 2009-03-25 2014-10-08 Proteus Digital Health Inc Probablistic pharmacokinetic and pharmacodynamic modeling
MX2011011506A (es) 2009-04-28 2012-05-08 Proteus Biomedical Inc Marcadores de eventos ingeribles altamente confiables y metodos para utilizar los mismos.
US9149423B2 (en) 2009-05-12 2015-10-06 Proteus Digital Health, Inc. Ingestible event markers comprising an ingestible component
WO2011005894A1 (en) * 2009-07-07 2011-01-13 Naya Touch, Inc. Dermal roller with therapeutic microstructures
US8558563B2 (en) 2009-08-21 2013-10-15 Proteus Digital Health, Inc. Apparatus and method for measuring biochemical parameters
TWI517050B (zh) 2009-11-04 2016-01-11 普羅托斯數位健康公司 供應鏈管理之系統
US10973994B2 (en) 2013-09-16 2021-04-13 Pourang Bral Means and method to invade skin, mucosa, and underlying tissues with little or no pain
US10226586B2 (en) 2011-05-26 2019-03-12 Pourang Bral Means and method to painlessly puncture skin
US9770560B2 (en) 2009-11-12 2017-09-26 Pourang Bral Means and method to administer injections with little or no pain
UA109424C2 (uk) 2009-12-02 2015-08-25 Фармацевтичний продукт, фармацевтична таблетка з електронним маркером і спосіб виготовлення фармацевтичної таблетки
US20110172659A1 (en) * 2010-01-13 2011-07-14 Vivant Medical, Inc. Ablation Device With User Interface at Device Handle, System Including Same, and Method of Ablating Tissue Using Same
AU2011210648B2 (en) 2010-02-01 2014-10-16 Otsuka Pharmaceutical Co., Ltd. Data gathering system
WO2011127252A2 (en) 2010-04-07 2011-10-13 Proteus Biomedical, Inc. Miniature ingestible device
TWI557672B (zh) 2010-05-19 2016-11-11 波提亞斯數位康健公司 用於從製造商跟蹤藥物直到患者之電腦系統及電腦實施之方法、用於確認將藥物給予患者的設備及方法、患者介面裝置
EP2642983A4 (de) 2010-11-22 2014-03-12 Proteus Digital Health Inc Einnehmbare vorrichtung mit einem pharmazeutischen produkt
US9439599B2 (en) 2011-03-11 2016-09-13 Proteus Digital Health, Inc. Wearable personal body associated device with various physical configurations
WO2015112603A1 (en) 2014-01-21 2015-07-30 Proteus Digital Health, Inc. Masticable ingestible product and communication system therefor
US9756874B2 (en) 2011-07-11 2017-09-12 Proteus Digital Health, Inc. Masticable ingestible product and communication system therefor
JP5963412B2 (ja) * 2011-09-14 2016-08-03 日立マクセル株式会社 美容装置
US9235683B2 (en) 2011-11-09 2016-01-12 Proteus Digital Health, Inc. Apparatus, system, and method for managing adherence to a regimen
ES2957620T3 (es) 2012-03-19 2024-01-23 Cidara Therapeutics Inc Regímenes de dosificación para los compuestos de la clase de las equinocandinas
RU2637104C2 (ru) 2012-05-07 2017-11-29 Конинклейке Филипс Н.В. Радиочастотная система для обработки кожи, включающая в себя ролик с электродом, а также способ обработки кожи
DE102012209008B4 (de) * 2012-05-29 2015-02-05 Wellcomet Gmbh Vorrichtung zum Erzeugen von Behandlungswellen
TW201424689A (zh) 2012-07-23 2014-07-01 Proteus Digital Health Inc 用於製造包含可吞服性組件的可吞服性事件標示器之技術
JP5580383B2 (ja) * 2012-10-05 2014-08-27 株式会社 資生堂 美容機器及び通電方法及び記録媒体
US9268909B2 (en) 2012-10-18 2016-02-23 Proteus Digital Health, Inc. Apparatus, system, and method to adaptively optimize power dissipation and broadcast power in a power source for a communication device
US20140194949A1 (en) * 2013-01-04 2014-07-10 Brian D. Wichner Multiplex Electrodes for Applying Transcutaneous Interferential Current
US11149123B2 (en) 2013-01-29 2021-10-19 Otsuka Pharmaceutical Co., Ltd. Highly-swellable polymeric films and compositions comprising the same
JP6498177B2 (ja) 2013-03-15 2019-04-10 プロテウス デジタル ヘルス, インコーポレイテッド 本人認証装置システムおよび方法
US10175376B2 (en) 2013-03-15 2019-01-08 Proteus Digital Health, Inc. Metal detector apparatus, system, and method
JP6511439B2 (ja) 2013-06-04 2019-05-15 プロテウス デジタル ヘルス, インコーポレイテッド データ収集および転帰の査定のためのシステム、装置、および方法
US9908140B2 (en) 2013-06-19 2018-03-06 Gilad Arwatz Electromechanical system for dispensing a composition
US9210985B2 (en) 2013-06-19 2015-12-15 Gilad Arwatz Electromechanical system for dispensing deodorant / antiperspirant
US9796576B2 (en) 2013-08-30 2017-10-24 Proteus Digital Health, Inc. Container with electronically controlled interlock
MX356850B (es) 2013-09-20 2018-06-15 Proteus Digital Health Inc Métodos, dispositivos y sistemas para recibir y decodificar una señal en presencia de ruido usando segmentos y deformaciones.
US9577864B2 (en) 2013-09-24 2017-02-21 Proteus Digital Health, Inc. Method and apparatus for use with received electromagnetic signal at a frequency not known exactly in advance
US10084880B2 (en) 2013-11-04 2018-09-25 Proteus Digital Health, Inc. Social media networking based on physiologic information
RU2699278C2 (ru) * 2014-05-02 2019-09-04 Конинклейке Филипс Н.В. Устройство для инактивации бактерий
GB201415611D0 (en) * 2014-09-03 2014-10-15 Univ Strathclyde Apparatus for topical application of material
US9839644B2 (en) 2014-09-09 2017-12-12 ARKAY Therapeutics, LLC Formulations and methods for treatment of metabolic syndrome
US11051543B2 (en) 2015-07-21 2021-07-06 Otsuka Pharmaceutical Co. Ltd. Alginate on adhesive bilayer laminate film
FR3043333B1 (fr) 2015-11-06 2017-12-22 Seb Sa Dispositif d'application d'un produit a distribuer sur la peau d'un utilisateur par iontophorese comprenant des moyens de mesure d'absence de produit et procede correspondant
FR3043332B1 (fr) * 2015-11-06 2019-05-10 Seb S.A. Dispositif d'application d'un produit a distribuer sur la peau d'un utilisateur par iontophorese
US10874325B2 (en) 2015-12-15 2020-12-29 Koninklijke Philips N.V. Surface treatment device and method
CN109843149B (zh) 2016-07-22 2020-07-07 普罗秋斯数字健康公司 可摄入事件标记的电磁感测和检测
JP2019535377A (ja) 2016-10-26 2019-12-12 プロテウス デジタル ヘルス, インコーポレイテッド 摂取可能なイベントマーカを有するカプセルの製造方法
JP6445105B2 (ja) * 2017-08-23 2018-12-26 マクセルホールディングス株式会社 美容システム
CN117258148A (zh) * 2017-09-01 2023-12-22 和尔科技股份有限公司 皮肤嫩化设备和方法
CN114081499B (zh) * 2021-11-23 2024-01-12 吉林大学 一种具有二梯度孔的柔性透气表面肌电电极及其制备方法

Family Cites Families (74)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3964482A (en) 1971-05-17 1976-06-22 Alza Corporation Drug delivery device
US4175551A (en) 1977-11-11 1979-11-27 Electromed Incorporated Electrical massage device
US4775361A (en) 1986-04-10 1988-10-04 The General Hospital Corporation Controlled removal of human stratum corneum by pulsed laser to enhance percutaneous transport
US4943290A (en) 1987-06-23 1990-07-24 Concept Inc. Electrolyte purging electrode tip
EP0398960B1 (de) 1988-01-21 1995-12-06 Massachusetts Institute Of Technology Molekültransport durch gewebe mit der verwendung von elektroporation
US5135478A (en) 1989-05-10 1992-08-04 Drug Delivery Systems Inc. Multi-signal electrical transdermal drug applicator
CA2071321C (en) 1989-05-10 2000-12-12 Dan Sibalis Multi-signal electrical transdermal drug applicator
WO1992013265A1 (en) 1991-01-24 1992-08-06 The University Of Maryland Method and apparatus for multi-dimensional phase fluorescence lifetime imaging
US5196709A (en) 1991-05-03 1993-03-23 University Of Maryland Systems Fluorometry method and apparatus using a semiconductor laser diode as a light source
EP0694164A1 (de) 1991-05-03 1996-01-31 Joseph R. Lakowicz Verfahren zur optischen Messung von chemischen Analyten
US5648269A (en) 1991-05-03 1997-07-15 Joseph R. Lakowicz pH and pCO2 sensing by luminescent lifetimes and energy transfer
US5571149A (en) 1991-05-21 1996-11-05 E.P., Inc. Non-intrusive analgesic neuroaugmentive and iontophoretic delivery apparatus and management system
US5421817A (en) 1991-05-21 1995-06-06 E.P., Inc. Non-intrusive analgesic neuroaugmentive and iontophoretic delivery apparatus and management system
US5203328A (en) 1991-07-17 1993-04-20 Georgia Tech Research Corporation Apparatus and methods for quantitatively measuring molecular changes in the ocular lens
US5281825A (en) 1991-09-05 1994-01-25 The University Of Maryland School Of Medicine Phase fluorometry using a modulated electroluminescent lamp as a light source
US5423803A (en) 1991-10-29 1995-06-13 Thermotrex Corporation Skin surface peeling process using laser
ATE143279T1 (de) 1991-12-03 1996-10-15 Alza Corp Iontophoretische verbreichungsvorrichtung und versorgungsnetz dafür
CA2084734C (en) 1991-12-17 1998-12-01 John L. Haynes Iontophoresis system having features for reducing skin irritation
US6210402B1 (en) 1995-11-22 2001-04-03 Arthrocare Corporation Methods for electrosurgical dermatological treatment
US6159194A (en) 1992-01-07 2000-12-12 Arthrocare Corporation System and method for electrosurgical tissue contraction
US6024733A (en) 1995-06-07 2000-02-15 Arthrocare Corporation System and method for epidermal tissue ablation
US5902272A (en) 1992-01-07 1999-05-11 Arthrocare Corporation Planar ablation probe and method for electrosurgical cutting and ablation
US5697882A (en) 1992-01-07 1997-12-16 Arthrocare Corporation System and method for electrosurgical cutting and ablation
US6142992A (en) 1993-05-10 2000-11-07 Arthrocare Corporation Power supply for limiting power in electrosurgery
EP0552108B1 (de) 1992-01-17 1999-11-10 Lakowicz, Joseph R. Phasenmodulationsenergieübertragungsfluoroimmunassay
US5246867A (en) 1992-01-17 1993-09-21 University Of Maryland At Baltimore Determination and quantification of saccharides by luminescence lifetimes and energy transfer
US5165418B1 (en) 1992-03-02 1999-12-14 Nikola I Tankovich Blood sampling device and method using a laser
US5232441A (en) 1992-05-18 1993-08-03 Physion S.R.L. Method of treating schistosomal infestations by iontophoresis
US5720772A (en) 1992-10-20 1998-02-24 Esc Medical Systems Ltd. Method and apparatus for therapeutic electromagnetic treatment
US5409835A (en) 1992-12-30 1995-04-25 The University Of Maryland At Baltimore Long-wavelength fluorescent probe compounds for calcium ions and their use in ratiometrically measuring calcium ion concentrations
US5380272A (en) 1993-01-28 1995-01-10 Scientific Innovations Ltd. Transcutaneous drug delivery applicator
JP2916736B2 (ja) 1993-03-04 1999-07-05 宇部興産株式会社 種子消毒剤
FR2703253B1 (fr) 1993-03-30 1995-06-23 Centre Nat Rech Scient Applicateur d'impulsions electriques pour traitement de tissus biologiques.
US5439440A (en) 1993-04-01 1995-08-08 Genetronics, Inc. Electroporation system with voltage control feedback for clinical applications
US6235020B1 (en) 1993-05-10 2001-05-22 Arthrocare Corporation Power supply and methods for fluid delivery in electrosurgery
US6117109A (en) 1995-11-22 2000-09-12 Arthrocare Corporation Systems and methods for electrosurgical incisions on external skin surfaces
US5445609A (en) 1993-05-28 1995-08-29 Alza Corporation Electrotransport agent delivery device having a disposable component and a removable liner
US5885211A (en) 1993-11-15 1999-03-23 Spectrix, Inc. Microporation of human skin for monitoring the concentration of an analyte
US5458140A (en) 1993-11-15 1995-10-17 Non-Invasive Monitoring Company (Nimco) Enhancement of transdermal monitoring applications with ultrasound and chemical enhancers
IL108775A (en) 1994-02-25 2003-09-17 Univ Ramot Method for efficient incorporation of molecules into cells
US5660991A (en) 1994-10-28 1997-08-26 Lakowicz; Joseph R. Long lifetime anisotropy (polarization) probes for clinical chemistry, immunoassays, affinity assays and biomedical research
US5697896A (en) 1994-12-08 1997-12-16 Alza Corporation Electrotransport delivery device
US5628310A (en) 1995-05-19 1997-05-13 Joseph R. Lakowicz Method and apparatus to perform trans-cutaneous analyte monitoring
US6238391B1 (en) 1995-06-07 2001-05-29 Arthrocare Corporation Systems for tissue resection, ablation and aspiration
US5983130A (en) 1995-06-07 1999-11-09 Alza Corporation Electrotransport agent delivery method and apparatus
US6041253A (en) 1995-12-18 2000-03-21 Massachusetts Institute Of Technology Effect of electric field and ultrasound for transdermal drug delivery
US5983131A (en) 1995-08-11 1999-11-09 Massachusetts Institute Of Technology Apparatus and method for electroporation of tissue
TR199800347T1 (xx) 1995-08-29 1998-05-21 Spectrx, Inc. �la� uygulamas� i�in insan derisinin mikro-g�zeneklendirilmesi ve uygulamalar�n g�zlemlenmesi.
US5688232A (en) 1995-09-28 1997-11-18 Becton Dickinson And Company Iontophoretic drug delivery device having an improved controller
US6228078B1 (en) 1995-11-22 2001-05-08 Arthrocare Corporation Methods for electrosurgical dermatological treatment
US6090106A (en) 1996-01-09 2000-07-18 Gyrus Medical Limited Electrosurgical instrument
US6045502A (en) 1996-01-17 2000-04-04 Spectrx, Inc. Analyzing system with disposable calibration device
US5924981A (en) 1996-01-17 1999-07-20 Spectrx, Inc. Disposable calibration target
US5860421A (en) 1996-01-17 1999-01-19 Spectrx, Inc. Apparatus and method for calibrating measurement systems
US5792049A (en) 1996-01-17 1998-08-11 Spectrx, Inc. Spectroscopic system with disposable calibration device
US6002482A (en) 1996-01-17 1999-12-14 Spectrx, Inc. Disposable calibration device
FR2746320B1 (fr) 1996-03-20 1998-06-05 Seb Sa Appareil de stimulation electrique indolore et procede correspondant
DE69722414T2 (de) 1996-07-03 2004-05-19 Altea Therapeutics Corp. Mehrfache mechanische mikroperforierung von haut oder schleimhäuten
US5911223A (en) 1996-08-09 1999-06-15 Massachusetts Institute Of Technology Introduction of modifying agents into skin by electroporation
US5759767A (en) 1996-10-11 1998-06-02 Joseph R. Lakowicz Two-photon and multi-photon measurement of analytes in animal and human tissues and fluids
US6076012A (en) 1996-12-19 2000-06-13 Ep Technologies, Inc. Structures for supporting porous electrode elements
US5938657A (en) 1997-02-05 1999-08-17 Sahar Technologies, Inc. Apparatus for delivering energy within continuous outline
US6030399A (en) 1997-06-04 2000-02-29 Spectrx, Inc. Fluid jet blood sampling device and methods
US6009344A (en) 1997-07-25 1999-12-28 Becton, Dickinson And Company Iontophoretic drug delivery system
WO1999029364A1 (en) 1997-12-11 1999-06-17 Alza Corporation Device for enhancing transdermal agent flux
WO1999029365A1 (en) 1997-12-11 1999-06-17 Alza Corporation Device for enhancing transdermal agent flux
US6055451A (en) 1997-12-12 2000-04-25 Spectrx, Inc. Apparatus and method for determining tissue characteristics
US6104952A (en) 1998-01-07 2000-08-15 Tu; Lily Chen Devices for treating canker sores, tissues and methods thereof
US6022316A (en) 1998-03-06 2000-02-08 Spectrx, Inc. Apparatus and method for electroporation of microporated tissue for enhancing flux rates for monitoring and delivery applications
US6173202B1 (en) 1998-03-06 2001-01-09 Spectrx, Inc. Method and apparatus for enhancing flux rates of a fluid in a microporated biological tissue
US6148232A (en) 1998-11-09 2000-11-14 Elecsys Ltd. Transdermal drug delivery and analyte extraction
US6088606A (en) 1999-03-22 2000-07-11 Spectrx, Inc. Method and apparatus for determining a duration of a medical condition
US7133717B2 (en) * 1999-08-25 2006-11-07 Johnson & Johnson Consumer Companies, Inc. Tissue electroperforation for enhanced drug delivery and diagnostic sampling
US7113821B1 (en) 1999-08-25 2006-09-26 Johnson & Johnson Consumer Companies, Inc. Tissue electroperforation for enhanced drug delivery

Also Published As

Publication number Publication date
AU2002307781B2 (en) 2007-01-25
IL158582A0 (en) 2004-05-12
WO2002085451A2 (en) 2002-10-31
WO2002085451A3 (en) 2003-05-08
JP2004528901A (ja) 2004-09-24
US20040230227A1 (en) 2004-11-18
EP1397178A2 (de) 2004-03-17
JP4262985B2 (ja) 2009-05-13
EP1502622A2 (de) 2005-02-02
ATE434464T1 (de) 2009-07-15
EP1502622A3 (de) 2005-06-08
US7164942B2 (en) 2007-01-16
EP1502622B1 (de) 2009-06-24
US6708060B1 (en) 2004-03-16
CA2445118A1 (en) 2002-10-31

Similar Documents

Publication Publication Date Title
DE60232747D1 (de) Handgerät zur transdermalen Verabreichung von Medikamenten und zur Entnahme von Körperflüssigkeiten
AU2010262696B2 (en) Structural arrangement for a wound dressing with a transcutaneous electric nerve stimulator
CA2413806A1 (en) Electrokinetic delivery device
WO2003026694A8 (en) Method and apparatus for treatment of viral infection
FR2844719B1 (fr) Dispositif electro-chimique pour le blanchiment d'un corps
WO2003089043A3 (en) Handheld transdermal drug delivery and analyte extraction
ES2012944A6 (es) Procedimiento y su dispositivo para la admionistracion de farmacos mediante ionoforesis, para tratamiento loco-regionales.
WO2007035710A3 (en) Electrokinetic delivery system and methods therefor
EP2392381A3 (de) Elektrische Stimulationsvorrichtung und Verfahren für die therapeutische Behandlung und Schmerzmanagement
ATE315420T1 (de) Elektrodenleitung zur stimulation von wirbelsaülen
NZ221013A (en) Transdermal device includes an electrical source and two electrodes
WO2005023361A3 (en) Disposable electric bandage
EP2357018A3 (de) Vorrichtung zur Behandlung von menschlichen oder tierischen Sperrmembranen
DE60021063D1 (de) Vorichtung zur behandlung von gewebe
DE60219336D1 (de) Vorrichtung zur iontophoretischen verabreichung von medikamenten durch das augenlid
ATE284172T1 (de) Steuerbare schlaufenstrukturen zur unterstützung von diagnostischen und therapeutischen elementen in kontakt mit körpergewebe
IE800248L (en) Iontophoretic treatment apparatus.
DE502004009820D1 (de) Behältnis und Vorrichtung zur Erzeugung von elektrischen Feldern in einzelnen Reaktionsräumen
AU564822B2 (en) Apparatus to detect electrically low resistance point of skin and apply stimulus the reto
ATE169832T1 (de) Ionophoretische vorrichtung zur transdermalen verabreichung von medikamenten undentsprechende wegwerfeinheit
EP1566198A2 (de) Handgerät zur Behandlung der Haut
JP3003001U (ja) イオン滲透治療を行う手動装置
JPS627866B2 (de)
ATE279957T1 (de) Vorrichtung zum transport von molekuelen durch die haut
JP2512015Y2 (ja) 殺菌装置

Legal Events

Date Code Title Description
8364 No opposition during term of opposition