DE60233350D1 - IMIDAZOi2,1-B -1,3,4-THIADIAZOLE SULFONAMIDES - Google Patents
IMIDAZOi2,1-B -1,3,4-THIADIAZOLE SULFONAMIDESInfo
- Publication number
- DE60233350D1 DE60233350D1 DE60233350T DE60233350T DE60233350D1 DE 60233350 D1 DE60233350 D1 DE 60233350D1 DE 60233350 T DE60233350 T DE 60233350T DE 60233350 T DE60233350 T DE 60233350T DE 60233350 D1 DE60233350 D1 DE 60233350D1
- Authority
- DE
- Germany
- Prior art keywords
- imidazoi2
- formula
- sulfonamides
- thiadiazole
- thiadiazole sulfonamides
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CA002364985A CA2364985A1 (en) | 2001-12-14 | 2001-12-14 | Imidazo(2,1-b)thiadiazole sulfonamides |
PCT/CA2002/001942 WO2003051890A1 (en) | 2001-12-14 | 2002-12-16 | Imidazo [2,1-b]-1,3,4-thiadiazole suflonamides |
Publications (1)
Publication Number | Publication Date |
---|---|
DE60233350D1 true DE60233350D1 (de) | 2009-09-24 |
Family
ID=4170835
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60233350T Expired - Lifetime DE60233350D1 (de) | 2001-12-14 | 2002-12-16 | IMIDAZOi2,1-B -1,3,4-THIADIAZOLE SULFONAMIDES |
Country Status (11)
Country | Link |
---|---|
US (8) | US7230019B2 (de) |
EP (1) | EP1463735B1 (de) |
JP (2) | JP2005519882A (de) |
AT (1) | ATE439363T1 (de) |
AU (1) | AU2002350333B2 (de) |
CA (1) | CA2364985A1 (de) |
DE (1) | DE60233350D1 (de) |
DK (1) | DK1463735T3 (de) |
ES (1) | ES2329882T3 (de) |
PT (1) | PT1463735E (de) |
WO (1) | WO2003051890A1 (de) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2364985A1 (en) * | 2001-12-14 | 2003-06-14 | John W. Gillard | Imidazo(2,1-b)thiadiazole sulfonamides |
WO2004111061A1 (en) * | 2003-06-13 | 2004-12-23 | Aegera Therapeutics Inc. | ACYLATED AND NON-ACYLATED IMIDAZO[2,1-b]-1,3,4,-THIADIAZOLE-2-SULFONAMIDES, AND USES THEREOF |
US20060135571A1 (en) * | 2003-06-13 | 2006-06-22 | Jaquith James B | Imidazo(2,1-b)-1,3,4-thiadiazole sulfoxides and sulfones |
WO2007034278A2 (en) * | 2005-09-19 | 2007-03-29 | Pfizer Products Inc. | Fused imidazole derivatives as c3a receptor antagonists |
US20090179638A1 (en) * | 2006-02-01 | 2009-07-16 | Aegera Therapeutics Inc. | Assay for identifying inhibitors of neuronal apoptotic pathways |
EP2106260B8 (de) | 2007-01-25 | 2018-04-04 | Naia Metabolic, Inc. | Insulin-sensibilisatoren und behandlungsverfahren damit |
US8563550B2 (en) * | 2007-09-27 | 2013-10-22 | Centro Nacional De Investigaciones Oncologicas (Cnio) | Imidazolothiadiazoles for use as protein kinase inhibitors |
CA2756873C (en) | 2009-04-02 | 2018-01-09 | Joaquin Pastor Fernandez | Imidazo [2,1-b] [1,3,4] thiadiazole derivatives |
US8771324B2 (en) | 2011-05-27 | 2014-07-08 | Globus Medical, Inc. | Securing fasteners |
EA201491967A1 (ru) | 2012-04-26 | 2015-03-31 | Бристол-Майерс Сквибб Компани | Производные имидазотиадиазола в качестве ингибиторов активируемых протеазой рецепторов 4 (par4) для лечения агрегации тромбоцитов |
KR20150003766A (ko) | 2012-04-26 | 2015-01-09 | 브리스톨-마이어스 스큅 컴퍼니 | 혈소판 응집을 치료하기 위한 프로테아제 활성화 수용체 4 (par4) 억제제로서의 이미다조티아디아졸 및 이미다조피리다진 유도체 |
ES2640916T3 (es) | 2012-04-26 | 2017-11-07 | Bristol-Myers Squibb Company | Derivados de imidazotiadiazol e imidazopirazina como inhibidores del receptor 4 activados por proteasa (PAR4) para tratar agregación plaquetaria |
JP6089110B2 (ja) * | 2013-09-30 | 2017-03-01 | 富士フイルム株式会社 | α−ハロゲノアセトフェノン化合物の製造方法、及びα−ブロモアセトフェノン化合物 |
US9617279B1 (en) | 2014-06-24 | 2017-04-11 | Bristol-Myers Squibb Company | Imidazooxadiazole compounds |
US9598419B1 (en) | 2014-06-24 | 2017-03-21 | Universite De Montreal | Imidazotriazine and imidazodiazine compounds |
WO2017184520A1 (en) * | 2016-04-18 | 2017-10-26 | Vanderbilt University | Substituted and fused 6-membered protease activated receptor 4 (par-4) antagonists |
CN112638919A (zh) * | 2018-08-30 | 2021-04-09 | 日本医事物理股份有限公司 | 放射性咪唑并噻二唑衍生物化合物 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US52514A (en) * | 1866-02-13 | Stove-pipe damper | ||
GB1464259A (en) * | 1975-10-03 | 1977-02-09 | Pfizer Ltd | Imidazo-thiazole and -thiadiazole sulphonamides and their use as therapeutic agents |
US5604202A (en) * | 1990-11-13 | 1997-02-18 | Albert Einstein College Of Medicine Of Yeshiva University, A Division Of Yeshiva University | Use of NGF growth factors to treat drug-induced neuropathy |
CN1295561A (zh) * | 1998-06-03 | 2001-05-16 | Gpinil控股公司 | N-杂环羧酸或羧酸等排物的n-结合氨磺酰 |
CA2364985A1 (en) * | 2001-12-14 | 2003-06-14 | John W. Gillard | Imidazo(2,1-b)thiadiazole sulfonamides |
CA2379375A1 (en) * | 2002-03-28 | 2003-09-28 | Apotex Inc. | Sulfonamide derivatives of 3-substituted imidazol[1,2-d]-1,2,4-thiadiazoles and 3-substituted-[1,2,4] thiadiazolo[4,5-a] benzimidazole as inhibitors of fibrin cross-linking and transglutaminases |
-
2001
- 2001-12-14 CA CA002364985A patent/CA2364985A1/en not_active Abandoned
-
2002
- 2002-12-16 DK DK02784979T patent/DK1463735T3/da active
- 2002-12-16 WO PCT/CA2002/001942 patent/WO2003051890A1/en active Application Filing
- 2002-12-16 US US10/498,548 patent/US7230019B2/en not_active Expired - Fee Related
- 2002-12-16 EP EP02784979A patent/EP1463735B1/de not_active Expired - Lifetime
- 2002-12-16 PT PT02784979T patent/PT1463735E/pt unknown
- 2002-12-16 ES ES02784979T patent/ES2329882T3/es not_active Expired - Lifetime
- 2002-12-16 JP JP2003552772A patent/JP2005519882A/ja active Pending
- 2002-12-16 AU AU2002350333A patent/AU2002350333B2/en not_active Ceased
- 2002-12-16 AT AT02784979T patent/ATE439363T1/de not_active IP Right Cessation
- 2002-12-16 DE DE60233350T patent/DE60233350D1/de not_active Expired - Lifetime
-
2006
- 2006-04-05 US US11/399,010 patent/US7741349B2/en not_active Expired - Fee Related
- 2006-04-06 US US11/399,033 patent/US7772260B2/en not_active Expired - Fee Related
- 2006-04-06 US US11/398,806 patent/US20070021416A1/en not_active Abandoned
-
2007
- 2007-05-07 US US11/797,665 patent/US7700635B2/en not_active Expired - Fee Related
- 2007-05-07 US US11/797,664 patent/US20070238768A1/en not_active Abandoned
- 2007-05-07 US US11/797,663 patent/US7714003B2/en not_active Expired - Fee Related
-
2008
- 2008-04-07 US US12/099,123 patent/US20090042953A1/en not_active Abandoned
-
2009
- 2009-12-22 JP JP2009291135A patent/JP2010106030A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
ES2329882T3 (es) | 2009-12-02 |
AU2002350333B2 (en) | 2008-08-21 |
US7714003B2 (en) | 2010-05-11 |
CA2364985A1 (en) | 2003-06-14 |
ATE439363T1 (de) | 2009-08-15 |
PT1463735E (pt) | 2009-10-15 |
EP1463735A1 (de) | 2004-10-06 |
JP2005519882A (ja) | 2005-07-07 |
US7741349B2 (en) | 2010-06-22 |
WO2003051890A1 (en) | 2003-06-26 |
DK1463735T3 (da) | 2009-12-14 |
US20070021416A1 (en) | 2007-01-25 |
US7772260B2 (en) | 2010-08-10 |
AU2002350333A1 (en) | 2003-06-30 |
US20070238766A1 (en) | 2007-10-11 |
US20070265319A1 (en) | 2007-11-15 |
US7700635B2 (en) | 2010-04-20 |
US20070021476A1 (en) | 2007-01-25 |
US20090042953A1 (en) | 2009-02-12 |
EP1463735B1 (de) | 2009-08-12 |
US20050069492A1 (en) | 2005-03-31 |
US7230019B2 (en) | 2007-06-12 |
US20070088059A1 (en) | 2007-04-19 |
JP2010106030A (ja) | 2010-05-13 |
US20070238768A1 (en) | 2007-10-11 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |