DE60336757D1 - Produktion von polyhydroxyalkanoat mittels coenzym-a-abhängiger aldehyd-dehydrogenase-wege - Google Patents

Produktion von polyhydroxyalkanoat mittels coenzym-a-abhängiger aldehyd-dehydrogenase-wege

Info

Publication number
DE60336757D1
DE60336757D1 DE60336757T DE60336757T DE60336757D1 DE 60336757 D1 DE60336757 D1 DE 60336757D1 DE 60336757 T DE60336757 T DE 60336757T DE 60336757 T DE60336757 T DE 60336757T DE 60336757 D1 DE60336757 D1 DE 60336757D1
Authority
DE
Germany
Prior art keywords
coa
organism
aldehyde dehydrogenase
dependent aldehyde
pha
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60336757T
Other languages
English (en)
Inventor
Frank A Skraly
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Metabolix Inc
Original Assignee
Metabolix Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Metabolix Inc filed Critical Metabolix Inc
Application granted granted Critical
Publication of DE60336757D1 publication Critical patent/DE60336757D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0008—Oxidoreductases (1.) acting on the aldehyde or oxo group of donors (1.2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/62—Carboxylic acid esters
    • C12P7/625—Polyesters of hydroxy carboxylic acids
DE60336757T 2002-09-12 2003-09-12 Produktion von polyhydroxyalkanoat mittels coenzym-a-abhängiger aldehyd-dehydrogenase-wege Expired - Lifetime DE60336757D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US41008702P 2002-09-12 2002-09-12
PCT/US2003/028842 WO2004024876A2 (en) 2002-09-12 2003-09-12 Polyhydroxyalkanoate production by coenzyme a-dependent aldehyde dehydrogenase pathways

Publications (1)

Publication Number Publication Date
DE60336757D1 true DE60336757D1 (de) 2011-05-26

Family

ID=31994056

Family Applications (2)

Application Number Title Priority Date Filing Date
DE60336757T Expired - Lifetime DE60336757D1 (de) 2002-09-12 2003-09-12 Produktion von polyhydroxyalkanoat mittels coenzym-a-abhängiger aldehyd-dehydrogenase-wege
DE10075400T Active DE10075400T8 (de) 2002-09-12 2003-09-12 Polyhydroxyalkanoatherstellung mittels Coenzym a-abhängigen Aldehyddehydrogenasepfaden

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE10075400T Active DE10075400T8 (de) 2002-09-12 2003-09-12 Polyhydroxyalkanoatherstellung mittels Coenzym a-abhängigen Aldehyddehydrogenasepfaden

Country Status (8)

Country Link
US (1) US8071355B2 (de)
EP (2) EP1581619B1 (de)
JP (2) JP4628103B2 (de)
AT (1) ATE505559T1 (de)
AU (1) AU2003267185A1 (de)
DE (2) DE60336757D1 (de)
ES (1) ES2395053T3 (de)
WO (1) WO2004024876A2 (de)

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KR100979694B1 (ko) * 2005-05-24 2010-09-02 한국과학기술원 폴리락테이트 또는 그 공중합체 생성능을 가지는 세포 또는식물 및 이를 이용한 폴리락테이트 또는 그 공중합체의제조방법
US8067214B2 (en) 2007-03-16 2011-11-29 Genomatica, Inc. Compositions and methods for the biosynthesis of 1,4-butanediol and its precursors
US7947483B2 (en) 2007-08-10 2011-05-24 Genomatica, Inc. Methods and organisms for the growth-coupled production of 1,4-butanediol
KR101114912B1 (ko) * 2008-06-24 2012-02-14 한국과학기술원 폴리락테이트와 그 공중합체 생성능이 개선된 변이 미생물을 이용한 폴리락테이트와 그 공중합체의 제조방법
CA2735883C (en) 2008-09-10 2020-05-05 Genomatica, Inc. Microorganisms for the production of 1,4-butanediol
US20100184173A1 (en) * 2008-11-14 2010-07-22 Genomatica, Inc. Microorganisms for the production of methyl ethyl ketone and 2-butanol
EP3260532A1 (de) 2008-12-12 2017-12-27 CJ Research Center LLC Grünes verfahren und zusammensetzungen zur herstellung von poly(5hv)- und 5-kohlenstoffchemikalien
KR101293886B1 (ko) * 2009-02-05 2013-08-07 주식회사 엘지화학 폴리락틱산 또는 폴리락틱산 공중합체 생성능을 지닌 재조합 랄스토니아 유트로파 및 이것을 이용하여 폴리락틱산 또는 폴리락틱산 공중합체를 제조하는 방법
US8129169B2 (en) 2009-06-04 2012-03-06 Genomatica, Inc. Microorganisms for the production of 1,4-butanediol and related methods
PL2438036T3 (pl) * 2009-06-04 2017-09-29 Genomatica, Inc. Sposób oddzielania składników brzeczki fermentacyjnej
US8377666B2 (en) * 2009-10-13 2013-02-19 Genomatica, Inc. Microorganisms for the production of 1,4-butanediol, 4-hydroxybutanal, 4-hydroxybutyryl-coa, putrescine and related compounds, and methods related thereto
WO2011066076A1 (en) 2009-11-25 2011-06-03 Genomatica, Inc. Microorganisms and methods for the coproduction of 1,4-butanediol and gamma-butyrolactone
US8637286B2 (en) 2010-02-23 2014-01-28 Genomatica, Inc. Methods for increasing product yields
US8048661B2 (en) * 2010-02-23 2011-11-01 Genomatica, Inc. Microbial organisms comprising exogenous nucleic acids encoding reductive TCA pathway enzymes
FR2964014B1 (fr) * 2010-08-31 2013-04-05 Ifremer Nucleus enrobe d'un revetement filmogene aux proprietes antibacteriennes et cicatrisantes et procede d'obtention.
FR2968506B1 (fr) * 2010-12-14 2013-02-08 Ifremer Nucleus recouvert de pha
CN102212501B (zh) * 2011-03-31 2013-06-12 山东大学 一种重组大肠杆菌及应用其以单一碳源生产phbv的方法
EP2702138A2 (de) * 2011-04-29 2014-03-05 Metabolix, Inc. Grünes verfahren zur herstellung von polyhydroxyalkanoaten und chemikalien unter verwendung eines erneuerbaren rohstoffes
MX348612B (es) 2011-08-19 2017-06-21 Genomatica Inc Microorganismos y metodos para producir 2,4 - pentadienoato, butadieno, propileno, 1,3 - butanodiol y alcoholes relacionados.
MY197970A (en) 2011-11-02 2023-07-25 Genomatica Inc Microorganisms and methods for the production of caprolactone
CN111705028A (zh) 2012-06-04 2020-09-25 基因组股份公司 制造4-羟基丁酸酯、1，4-丁二醇和相关化合物的微生物和方法
KR20150069015A (ko) 2012-10-15 2015-06-22 게노마티카 인코포레이티드 특정 길이의 지방 알콜 및 관련 화합물의 생산을 위한 미생물 및 방법
BR112015020904A2 (pt) 2013-03-15 2017-10-10 Genomatica Inc microrganismos e métodos para produção de butadieno e compostos relacionados por assimilação de formiato
EP3074504A4 (de) 2013-11-25 2017-05-03 Genomatica, Inc. Verfahren zur verbesserung der mikrobiellen herstellung von fettalkoholen mit bestimmter länge in gegenwart von methanol
WO2016007365A1 (en) 2014-07-11 2016-01-14 Genomatica, Inc. Microorganisms and methods for the production of butadiene using acetyl-coa
EP3741865B1 (de) 2014-09-18 2024-03-13 Genomatica, Inc. Nicht-natürliche mikrobielle organismen mit verbesserter energieeffizienz
US10941454B2 (en) 2015-05-30 2021-03-09 Genomatica, Inc. Vinylisomerase-dehydratases, alkenol dehydratases, linalool dehydratases and crotyl alcohol dehydratases and methods for making and using them
US11566250B2 (en) 2017-10-26 2023-01-31 Noroo Ic Co., Ltd. Production and separation of 3-hydroxypropionic acid
CN112368384A (zh) 2017-10-26 2021-02-12 诺鲁Ic有限公司 3-羟基丙酸的生产与分离
WO2021085120A1 (ja) * 2019-10-31 2021-05-06 株式会社カネカ ポリヒドロキシアルカン酸の製造方法およびその利用

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US4477654A (en) 1981-07-07 1984-10-16 Imperial Chemical Industries Plc 3-Hydroxybutyrate polymers
EP0145233B2 (de) 1983-11-23 1991-11-06 Imperial Chemical Industries Plc Trennungsverfahrenfür ein 3-hydroxybutyrat-Polymer
US5480794A (en) 1987-06-29 1996-01-02 Massachusetts Institute Of Technology And Metabolix, Inc. Overproduction and purification of soluble PHA synthase
US5229279A (en) 1987-06-29 1993-07-20 Massachusetts Institute Of Technology Method for producing novel polyester biopolymers
US5245023A (en) 1987-06-29 1993-09-14 Massachusetts Institute Of Technology Method for producing novel polyester biopolymers
US5250430A (en) 1987-06-29 1993-10-05 Massachusetts Institute Of Technology Polyhydroxyalkanoate polymerase
GB9325952D0 (en) * 1993-12-20 1994-02-23 Zeneca Ltd Process for preparing films and coatings
ZA95627B (en) 1994-01-28 1995-10-05 Procter & Gamble Biodegradable copolymers and plastic articles comprising biodegradable copolymers
SG47812A1 (en) 1994-01-28 1998-04-17 Procter & Gamble Biodegradable copolymers and plastic articles comprising biodegradable copolymers of 3-hydroxyhexanoate
FR2719012B1 (fr) 1994-04-22 1996-07-12 Pomagalski Sa Pince débrayable d'un véhicule tracté par câble.
US5563239A (en) 1994-11-09 1996-10-08 Eastman Chemical Company Composition and process for the production of poly(3-hydroxyalkanoates)
WO1998039453A1 (en) * 1997-03-03 1998-09-11 Monsanto Company Methods for the biosynthesis of polyesters
JP2001516574A (ja) 1997-09-19 2001-10-02 メタボリックス，インコーポレイテッド ４−ヒドロキシ酸を含むポリヒドロキシアルカノエートポリマー製造のための生物学的システム
US7455999B2 (en) 1998-01-22 2008-11-25 Metabolix, Inc. Transgenic systems for the manufacture of poly (3-hydroxy-butyrate-co-3-hydroxyhexanoate)
EP1975236B1 (de) * 1998-08-04 2015-05-06 Metabolix, Inc. Herstellung von Polyhydroxyalkanoat aus Polyolen
WO2000011188A1 (en) * 1998-08-18 2000-03-02 Metabolix, Inc. Transgenic microbial polyhydroxyalkanoate producers
EP2305324B1 (de) * 1999-03-25 2014-09-17 Metabolix, Inc. Medizinische Geräte und Anwendungen aus Polyhydroxyalkanoat-Polymeren
KR20040014389A (ko) * 2000-07-21 2004-02-14 메타볼릭스 인코포레이티드 폴리올로부터 폴리하이드록시알칸노에이트를 제조하는 방법
AU2002225827A1 (en) * 2000-10-27 2002-05-06 Metabolix, Inc. Compositions comprising low molecular weight polyhydroxyalkanoates and methods employing same

Also Published As

Publication number Publication date
DE10075400T1 (de) 2012-10-11
WO2004024876A2 (en) 2004-03-25
ATE505559T1 (de) 2011-04-15
JP2010268797A (ja) 2010-12-02
AU2003267185A1 (en) 2004-04-30
EP1581619A4 (de) 2007-02-14
EP1581619A2 (de) 2005-10-05
AU2003267185A8 (en) 2004-04-30
JP2006507811A (ja) 2006-03-09
EP2365088A2 (de) 2011-09-14
ES2395053T3 (es) 2015-10-08
ES2395053T1 (es) 2013-02-07
US20040106176A1 (en) 2004-06-03
EP2365088B1 (de) 2015-05-27
US8071355B2 (en) 2011-12-06
WO2004024876A3 (en) 2006-05-26
JP4628103B2 (ja) 2011-02-09
DE10075400T8 (de) 2013-04-25
EP1581619B1 (de) 2011-04-13
EP2365088A3 (de) 2012-01-11

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