DE68919154D1 - Benzodiazepinverbindungen und ihre Verwendung als Arzneimittel. - Google Patents

Benzodiazepinverbindungen und ihre Verwendung als Arzneimittel.

Info

Publication number
DE68919154D1
DE68919154D1 DE68919154T DE68919154T DE68919154D1 DE 68919154 D1 DE68919154 D1 DE 68919154D1 DE 68919154 T DE68919154 T DE 68919154T DE 68919154 T DE68919154 T DE 68919154T DE 68919154 D1 DE68919154 D1 DE 68919154D1
Authority
DE
Germany
Prior art keywords
medicines
benzodiazepine compounds
benzodiazepine
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE68919154T
Other languages
English (en)
Other versions
DE68919154T2 (de
Inventor
Jiban Kumar Chakrabarti
Terrence Michael Hotten
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Lilly Industries Ltd
Original Assignee
Lilly Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Industries Ltd filed Critical Lilly Industries Ltd
Publication of DE68919154D1 publication Critical patent/DE68919154D1/de
Application granted granted Critical
Publication of DE68919154T2 publication Critical patent/DE68919154T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
DE68919154T 1988-08-11 1989-08-09 Benzodiazepinverbindungen und ihre Verwendung als Arzneimittel. Expired - Fee Related DE68919154T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB888819059A GB8819059D0 (en) 1988-08-11 1988-08-11 Benzodiazepine compounds & their use as pharmaceuticals

Publications (2)

Publication Number Publication Date
DE68919154D1 true DE68919154D1 (de) 1994-12-08
DE68919154T2 DE68919154T2 (de) 1995-03-09

Family

ID=10641942

Family Applications (1)

Application Number Title Priority Date Filing Date
DE68919154T Expired - Fee Related DE68919154T2 (de) 1988-08-11 1989-08-09 Benzodiazepinverbindungen und ihre Verwendung als Arzneimittel.

Country Status (22)

Country Link
US (2) US4977150A (de)
EP (1) EP0354781B1 (de)
JP (1) JP2779219B2 (de)
KR (1) KR0138527B1 (de)
CN (1) CN1025857C (de)
AR (1) AR246972A1 (de)
AT (1) ATE113600T1 (de)
AU (1) AU625067B2 (de)
CA (1) CA1318669C (de)
DE (1) DE68919154T2 (de)
DK (1) DK393489A (de)
ES (1) ES2062012T3 (de)
GB (1) GB8819059D0 (de)
HU (1) HU202239B (de)
IE (1) IE64598B1 (de)
IL (1) IL91246A (de)
MX (1) MX17107A (de)
NZ (1) NZ230251A (de)
PH (1) PH27010A (de)
PT (1) PT91401B (de)
RU (1) RU2002752C1 (de)
ZA (1) ZA896039B (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE1004596A4 (fr) * 1990-09-26 1992-12-22 Therabel Res S A N V Derives de methylpiperazinoazepine, leur preparation et leur utilisation.
US5627178A (en) 1991-04-23 1997-05-06 Lilly Industries Limited 2-methyl-thieno-benzodiazepine
US5393752A (en) * 1992-05-26 1995-02-28 Therabel Research S.A./N.V. Methylpiperazinoazepine compounds, preparation and use thereof
US6034078A (en) * 1992-05-29 2000-03-07 Eli Lilly And Company Limited Thienobenzodiazepine compounds
US6617321B2 (en) * 1997-09-30 2003-09-09 Eli Lilly And Company 2-methyl-thieno-benzodiazepine formulation
US7214673B2 (en) 2002-03-28 2007-05-08 Eli Lilly And Company Piperazine substituted aryl benzodiazepines and their use as dopamine receptor antagonists for the treatment of psychotic disorders
ES2285227T3 (es) 2002-08-05 2007-11-16 Eli Lilly And Company Arilbenzodiazepinas sustituidas con piperazina.
CA2536107A1 (en) * 2003-09-09 2005-03-24 Eli Lilly And Company Substituted piperazines of azepines, oxazepines, and thiazepines
US7932249B2 (en) * 2005-01-05 2011-04-26 Eli Lilly And Company Olanzapine pamoate dihydrate

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH468400A (de) * 1965-12-23 1969-02-15 Sandoz Ag Verfahren zur Herstellung neuer Thieno(2,3-b)(1,5)benzothiazepin-4-on-Verbindungen
US3758479A (en) * 1967-03-22 1973-09-11 Sandoz Ag Nitro and sulphamoyl substituted dibenzodiazepines
US3539573A (en) * 1967-03-22 1970-11-10 Jean Schmutz 11-basic substituted dibenzodiazepines and dibenzothiazepines
GB1292410A (en) * 1970-05-13 1972-10-11 Yoshitomi Pharmaceutical Thienobenzothiazepine derivatives
CH554362A (de) * 1970-07-30 1974-09-30 Spofa Vereinigte Pharma Werke Verfahren zur herstellung von neuen estern tricyklischer piperazinoalkanole.
US3897446A (en) * 1973-09-04 1975-07-29 Upjohn Co 6-Phenylthiazolo{8 3,2-a{9 {8 1,4{9 benzodiazepin-1-(2H)-ones, and processes
SU629879A3 (ru) * 1974-11-26 1978-10-25 Лилли Индастриз Лимитед, (Фирма) Способ получени тиено(1,5) бензодиазепинов или их солей
US4115568A (en) * 1974-11-26 1978-09-19 Lilly Industries Limited Thieno[3,2-b]-[1,5]benzodiazepines
US3951981A (en) * 1975-02-24 1976-04-20 American Cyanamid Company Substituted benzodiazepines and method of use
US4404137A (en) * 1979-10-16 1983-09-13 Lilly Industries Limited Pyrazolo [3,4-b][1,5]benzodiazepine compounds
US4431589A (en) * 1980-12-11 1984-02-14 Lilly House Benzodiazepine compounds and their use as pharmaceuticals

Also Published As

Publication number Publication date
AU625067B2 (en) 1992-07-02
ZA896039B (en) 1991-04-24
EP0354781A2 (de) 1990-02-14
IL91246A (en) 1994-01-25
NZ230251A (en) 1992-05-26
CN1040798A (zh) 1990-03-28
CN1025857C (zh) 1994-09-07
CA1318669C (en) 1993-06-01
AR246972A1 (es) 1994-10-31
AU3939989A (en) 1990-02-15
DE68919154T2 (de) 1995-03-09
PH27010A (en) 1993-02-01
HUT53109A (en) 1990-09-28
ES2062012T3 (es) 1994-12-16
GB8819059D0 (en) 1988-09-14
IE892576L (en) 1990-02-11
PT91401B (pt) 1995-05-04
EP0354781A3 (de) 1991-04-03
ATE113600T1 (de) 1994-11-15
US4977150A (en) 1990-12-11
KR900003179A (ko) 1990-03-23
IL91246A0 (en) 1990-03-19
DK393489A (da) 1990-02-12
JP2779219B2 (ja) 1998-07-23
RU2002752C1 (ru) 1993-11-15
US5051516A (en) 1991-09-24
HU202239B (en) 1991-02-28
EP0354781B1 (de) 1994-11-02
JPH02104591A (ja) 1990-04-17
IE64598B1 (en) 1995-08-23
PT91401A (pt) 1990-03-08
KR0138527B1 (ko) 1998-05-15
MX17107A (es) 1993-08-01
DK393489D0 (da) 1989-08-10

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee