DE68926507D1 - Nachweis des humanen papillomavirus unter verwendung der polymerase-kettenreaktion - Google Patents

Nachweis des humanen papillomavirus unter verwendung der polymerase-kettenreaktion

Info

Publication number
DE68926507D1
DE68926507D1 DE68926507T DE68926507T DE68926507D1 DE 68926507 D1 DE68926507 D1 DE 68926507D1 DE 68926507 T DE68926507 T DE 68926507T DE 68926507 T DE68926507 T DE 68926507T DE 68926507 D1 DE68926507 D1 DE 68926507D1
Authority
DE
Germany
Prior art keywords
hpv
chain reaction
polymerase chain
human papillomavirus
dna
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE68926507T
Other languages
English (en)
Other versions
DE68926507T2 (de
Inventor
M Manos
Deann Wright
Yi Ting
Thomas Broker
Steven Wolinsky
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of DE68926507D1 publication Critical patent/DE68926507D1/de
Application granted granted Critical
Publication of DE68926507T2 publication Critical patent/DE68926507T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844Nucleic acid amplification reactions
    • C12Q1/686Polymerase chain reaction [PCR]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701Specific hybridization probes
    • C12Q1/708Specific hybridization probes for papilloma
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/81Packaged device or kit
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00Chemistry: analytical and immunological testing
    • Y10S436/811Test for named disease, body condition or organ function
DE68926507T 1988-09-09 1989-08-29 Nachweis des humanen papillomavirus unter verwendung der polymerase-kettenreaktion Expired - Lifetime DE68926507T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US24348688A 1988-09-09 1988-09-09
US07/322,550 US5182377A (en) 1988-09-09 1989-03-10 Probes for detection of human papillomavirus
PCT/US1989/003747 WO1990002821A1 (en) 1988-09-09 1989-08-29 Detection of human papillomavirus by the polymerase chain reaction

Publications (2)

Publication Number Publication Date
DE68926507D1 true DE68926507D1 (de) 1996-06-20
DE68926507T2 DE68926507T2 (de) 1997-01-16

Family

ID=26935890

Family Applications (1)

Application Number Title Priority Date Filing Date
DE68926507T Expired - Lifetime DE68926507T2 (de) 1988-09-09 1989-08-29 Nachweis des humanen papillomavirus unter verwendung der polymerase-kettenreaktion

Country Status (8)

Country Link
US (2) US5182377A (de)
EP (1) EP0433396B1 (de)
JP (1) JP2651483B2 (de)
AT (1) ATE138108T1 (de)
AU (1) AU645483B2 (de)
CA (1) CA1339262C (de)
DE (1) DE68926507T2 (de)
WO (1) WO1990002821A1 (de)

Families Citing this family (87)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5876922A (en) 1985-07-31 1999-03-02 Institute Pasteur Papillomavirus probe and a process for in vitro diagnosis of papillomavirus infections
CA1276575C (fr) * 1984-11-30 1990-11-20 Sylvie Beaudenon Sondes a papillomavirus et procede de diagnostic in vitro d'infections a papillomavirus
DE3779175D1 (de) 1986-03-21 1992-06-25 Pasteur Institut Bestimmte, von einem papillomavirus-genom abgeleitete dns-sequenzen, deren anwendungen fuer in vitro-diagnostische zwecke und die herstellung von antigenzusammensetzungen.
FR2632956B2 (fr) * 1988-05-13 1991-07-12 Pasteur Institut Sondes a papillomavirus hpv49, hpv50, hpv54, hpv55; produits genetiquement et immunologiquement lies a ce papillomavirus hpv49, hpv50, hpv54, hpv55; procede de diagnostic in vitro d'infections a papillomavirus et d'immunisation in vivo contre ces papillomavirus
US5639871A (en) * 1988-09-09 1997-06-17 Roche Molecular Systems, Inc. Detection of human papillomavirus by the polymerase chain reaction
US5447839A (en) * 1988-09-09 1995-09-05 Hoffmann-La Roche Inc. Detection of human papillomavirus by the polymerase chain reaction
DE3838269A1 (de) * 1988-11-11 1990-05-17 Behringwerke Ag Nachweis humaner papillomavirus dna und ihrer expression in zervix-abstrichen
US5043272A (en) * 1989-04-27 1991-08-27 Life Technologies, Incorporated Amplification of nucleic acid sequences using oligonucleotides of random sequence as primers
US5106727A (en) * 1989-04-27 1992-04-21 Life Technologies, Inc. Amplification of nucleic acid sequences using oligonucleotides of random sequences as primers
JP2791685B2 (ja) * 1989-06-08 1998-08-27 寳酒造株式会社 パピローマウイルスの検出方法
US5863717A (en) * 1989-11-03 1999-01-26 Abbott Laboratories Use of conserved oligonucleotide primers to amplify human papillomavirus DNA sequences
US5580970A (en) * 1989-12-01 1996-12-03 Amoco Corporation Detection of HPV transcripts
EP0502994B1 (de) * 1989-12-01 1995-09-06 Amoco Corporation Detektion von hpv-transkripts
US5811232A (en) * 1989-12-04 1998-09-22 Isis Pharmaceuticals, Inc. Oligonucleotides for Papillomavirus
NL9000134A (nl) * 1990-01-19 1991-08-16 Stichting Res Fonds Pathologie Primers en werkwijze voor het detecteren van humaan papilloma virus genotypen m.b.v. pcr.
GB9015845D0 (en) * 1990-07-19 1990-09-05 Emery Vincent C Diagnostic method
US5484699A (en) * 1990-09-28 1996-01-16 Abbott Laboratories Nucleotide sequences useful as type specific probes, PCR primers and LCR probes for the amplification and detection of human papilloma virus, and related kits and methods
CA2052413C (en) * 1990-09-28 2004-07-13 Jeffrey L. Joseph Nucleotides sequences useful as type-specific probes, pcr primers and lcr probes for the amplifications and detection of human papilloma virus, and related kits and methods
IT1244462B (it) * 1990-12-06 1994-07-15 Sclavo Spa Oligonucleotidi sintetici utili per la diagnosi di infezione da tipi diversi di virus del gruppo papilloma e loro utilizzazione
US5538869A (en) * 1990-12-13 1996-07-23 Board Of Regents, The University Of Texas System In-situ hybridization probes for identification and banding of specific human chromosomes and regions
FR2670797A1 (fr) * 1990-12-20 1992-06-26 Pasteur Institut Sequences d'adn determinees derivees du genome du papillomavirus hpv39, application de ces sequences au diagnostic in vitro d'infection par ce papillomavirus, et a la production de composition immunogene.
IL97226A0 (en) * 1991-02-13 1992-05-25 Orgenics Ltd Detection of high and low risk human papillomavirus by enzymatic amplification of dna
US5427932A (en) * 1991-04-09 1995-06-27 Reagents Of The University Of California Repeat sequence chromosome specific nucleic acid probes and methods of preparing and using
JPH0686697A (ja) * 1991-04-09 1994-03-29 Univ California 反復配列染色体特異的核酸プローブ
US5283175A (en) * 1991-04-15 1994-02-01 The Research Foundation Of State University Of New York Genus-specific oligomers of Borrelia and methods of using same
FR2679254B1 (fr) * 1991-07-17 1993-11-19 Clonatec Sondes oligonucleotidiques pour le typage et la detection des papillomavirus humains.
US5346811A (en) * 1991-07-22 1994-09-13 Cerveceria Polar Method and products for human papillomavirus detection
ES2092056T3 (es) * 1991-09-23 1996-11-16 Pfizer Procedimiento para detectar arnm y adn especificos en celulas.
US5589333A (en) * 1992-02-03 1996-12-31 Thomas Jefferson University In situ polymerase chain reaction
US5859230A (en) * 1992-07-30 1999-01-12 Genelabs Technologies, Inc. Non-A/non-B/non-C/non-D/non-E hepatitis agents and molecular cloning thereof
CA2161337A1 (en) * 1993-05-06 1994-11-24 Denis R. Henrard Direct lysis buffer and the detection of hiv-1 plasma viremia
ES2181765T3 (es) * 1994-02-21 2003-03-01 Stichting Res Fonds Pathologie Deteccion de papiloma virus humano en un proceso de amplificacion de acido nucleico utilizando cebadores generales.
DE4420732A1 (de) * 1994-06-15 1995-12-21 Boehringer Mannheim Gmbh Vorrichtung zur Behandlung von Nukleinsäuren aus einer Probe
US5702886A (en) * 1994-10-05 1997-12-30 The Johns Hopkins University Chromosome I8Q loss and prognosis in colorectal cancer
US5935825A (en) * 1994-11-18 1999-08-10 Shimadzu Corporation Process and reagent for amplifying nucleic acid sequences
US6509149B2 (en) * 1995-06-06 2003-01-21 Hybridon, Inc. HPV-specific oligonucleotides
US6458940B2 (en) * 1995-06-06 2002-10-01 Hybridon, Inc. HPV-specific oligonucleotides
US20030055240A1 (en) * 1995-06-06 2003-03-20 Roberts Peter C. HPV specific oligonucleotides
US5731150A (en) * 1995-11-01 1998-03-24 Chiron Diagnostic Corporation IS6110 based molecular detection of mycobacterium tuberculosis
AU726047B2 (en) 1995-11-15 2000-10-26 Gen-Probe Incorporated Nucleic acid probes complementary to human papillomavirus nucleic acid and related methods and kits
US5888736A (en) * 1995-12-22 1999-03-30 Visible Genetics, Inc. Method, compositions and kit for detection and identification of microorganisms
US5795722A (en) * 1997-03-18 1998-08-18 Visible Genetics Inc. Method and kit for quantitation and nucleic acid sequencing of nucleic acid analytes in a sample
US6007983A (en) * 1995-12-22 1999-12-28 Visible Genetics Inc. Method and kit for evaluation of HIV mutations
US6265152B1 (en) 1995-12-22 2001-07-24 Visible Genetics Inc. Method and kit for evaluation of HIV mutations
US6511805B1 (en) * 1996-03-15 2003-01-28 The Penn State Research Foundation Methods for detecting papillomavirus DNA in blood plasma and serum
US8048629B2 (en) * 1996-03-15 2011-11-01 The Penn State Research Foundation Detection of extracellular tumor-associated nucleic acid in blood plasma or serum
EP0929694A4 (de) 1996-03-15 2002-05-02 Penn State Res Found Nachweis von extrazellulärer tumor-assoziierter nukleinsäuren im blutplasma oder -serum mittels eines nukleinsäure-amplifizierungsverfahren
AU2672597A (en) * 1996-04-15 1997-11-07 University Of New Mexico Probes for the detection of human papillomavirus
US6413718B1 (en) 1996-05-01 2002-07-02 Visible Genetics Inc. Method for sequencing of nucleic acid polymers
US6830887B2 (en) 1997-03-18 2004-12-14 Bayer Healthcare Llc Method and kit for quantitation and nucleic acid sequencing of nucleic acid analytes in a sample
WO1999014377A2 (en) 1997-09-16 1999-03-25 Innogenetics N.V. Detection and identification of human papillomavirus by pcr and type-specific reverse hybridization
US6703228B1 (en) * 1998-09-25 2004-03-09 Massachusetts Institute Of Technology Methods and products related to genotyping and DNA analysis
DE69936841D1 (de) * 1998-10-26 2007-09-27 Ventana Med Syst Inc Nachweis des humanen papilloma-virus mit hilfe des papanicolau-tests
US7569344B2 (en) * 1998-10-26 2009-08-04 Ventana Medical Systems, Inc. Detection of human papilloma virus in papanicolaou (Pap) smears
SE515668C2 (sv) * 1999-02-22 2001-09-17 Quantovir Ab Metod och kit för tidig förutsägelse av cancer
US6420106B1 (en) 1999-06-09 2002-07-16 Quantovir Ab Method and kit for early cancer prediction
US20060275784A1 (en) * 1999-10-26 2006-12-07 Ventana Medical Systems, Inc. Detection of Human Papilloma Virus in Papanicolaou (Pap) Smears
AU2001256976A1 (en) * 2000-04-03 2001-10-15 Cytyc Corporation Detection and typing of human papillomavirus using pna probes
US6936443B2 (en) * 2000-04-03 2005-08-30 Cytyc Corporation Detection and typing of human papillomavirus using PNA probes
IT1316070B1 (it) * 2000-05-05 2003-03-28 Bioanalisi Ct Sud Snc Di Perse Metodo e mezzi per l'identificazione di virus hpv
US20030059806A1 (en) * 2001-01-05 2003-03-27 Science & Technology Corporation @ Unm Probes for the detection of human papillomavirus
US6811549B2 (en) * 2001-02-16 2004-11-02 William H. Fleming Administration of therapeutic or diagnostic agents using interlabial pad
US8142819B2 (en) 2002-10-21 2012-03-27 Metaproteomics, Llc Synergistic compositions that treat or inhibit pathological conditions associated with inflammatory response
US7222059B2 (en) * 2001-11-15 2007-05-22 Siemens Medical Solutions Diagnostics Electrophoretic trace simulator
MXPA04006440A (es) 2002-01-07 2005-03-31 Norchip As Metodo para detectar arnm de papilomavirus humano.
HUP0200981A3 (en) 2002-03-14 2004-06-28 Genoid Kft Pcr reactions with hybridizing probes using primers with broad genotype-specificity for detection of human papilloma-viruses and typing amplificates by using specifically hybridizing oligonucleotides
US7531305B2 (en) * 2002-04-16 2009-05-12 Autogenomics, Inc. Human Papilloma Virus detection with DNA microarray
KR100452103B1 (ko) * 2002-07-16 2004-10-08 (주)차웰빙스 중합효소연쇄반응에 의한 종양원성 인유두종바이러스를검출하기 위한 프라이머와 종양원성 인유두종바이러스를검출하는 방법
KR100491842B1 (ko) * 2002-11-29 2005-05-27 (주)차웰빙스 중합효소연쇄반응에 의한 다양한 유형의인유두종바이러스를 검출하기 위한 신규한 피씨알 공통프라이머와 그를 이용한 인유두종바이러스를 검출하는 방법
US7527948B2 (en) 2003-09-25 2009-05-05 Third Wave Technologies, Inc. Detection of HPV
US20050130177A1 (en) 2003-12-12 2005-06-16 3M Innovative Properties Company Variable valve apparatus and methods
US7939249B2 (en) * 2003-12-24 2011-05-10 3M Innovative Properties Company Methods for nucleic acid isolation and kits using a microfluidic device and concentration step
DE102004022350A1 (de) * 2004-04-29 2005-11-17 Genid Gmbh Diagnose von Infektionserkrankungen
KR100645253B1 (ko) 2004-07-12 2006-11-15 (주)차바이오메드 중합효소연쇄반응에 의해 인유두종바이러스 유형을결정하기 위한 유형 특이적 올리고뉴클레오타이드 및프라이머와 이를 이용한 결정 방법.
EP1623996A1 (de) * 2004-08-06 2006-02-08 Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts Verbessertes Verfahren zur Auswahl eines Proteins von einer Bibliothek
US20070238100A1 (en) * 2004-11-30 2007-10-11 Mcglennen Ronald C Integrated methodologies for the detection and genotyping of human papillomaviruses
AU2005314061B2 (en) 2004-12-08 2010-01-28 Gen-Probe Incorporated Detection of nucleic acids from multiple types of human papillomaviruses
US20060161076A1 (en) * 2005-01-06 2006-07-20 Diamics, Inc. Systems and methods for collection of cell clusters
US20060189893A1 (en) * 2005-01-06 2006-08-24 Diamics, Inc. Systems and methods for detecting abnormal cells
US20070031826A1 (en) * 2005-08-05 2007-02-08 My Gene Diagnostic kit for determining the genotype of a human papilloma virus and method of using thereof
EP2759307B1 (de) 2006-03-29 2016-11-09 Merial Limited Impfstoff gegen Streptokokken
US7445786B1 (en) 2006-04-10 2008-11-04 Manuela Rehtanz Diagnosing and protecting against tursiops truncatus papillomavirus
US8080643B2 (en) * 2006-09-05 2011-12-20 Third Wave Technologies, Inc. HPV primers
WO2008106610A1 (en) * 2007-02-28 2008-09-04 Quantrx Biomedical Corporation Folded perineal pad
WO2009011472A1 (en) * 2007-07-19 2009-01-22 Hyunil Choi Primers and proves for detection of high risk group geno-type human papillomavirus dna, a qualitative assay method of the same dna using them and a qualitative assay kit of the same dna
JP6153866B2 (ja) 2010-05-25 2017-06-28 キアゲン ガイサーズバーグ アイエヌシー. 迅速なハイブリッド捕捉アッセイ、及び関連する戦略的に切断されたプローブ
US10982852B2 (en) * 2018-11-05 2021-04-20 Rolls-Royce Corporation Cowl integration to combustor wall

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1276575C (fr) * 1984-11-30 1990-11-20 Sylvie Beaudenon Sondes a papillomavirus et procede de diagnostic in vitro d'infections a papillomavirus
FR2593828B2 (fr) * 1986-01-31 1990-05-04 Pasteur Institut Sonde a papillomavirus et procede de diagnostic in-vitro d'infections a papillomavirus
US4683195A (en) * 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
ATE79138T1 (de) * 1985-04-04 1992-08-15 Univ Georgetown Typenspezifische papillomavirus-dns-sequenzen und peptide.
WO1988006634A1 (en) * 1987-02-26 1988-09-07 The University Of Sydney A method of detection of carcinogenic human papillomavirus
US4849332A (en) * 1987-05-26 1989-07-18 Life Technologies, Inc. Human papillomavirus 35 nucleic acid hybridization probes and methods for employing the same
US4849334A (en) * 1987-06-09 1989-07-18 Life Technologies, Inc. Human papillomavirus 43 nucleic acid hybridization probes and methods for employing the same
US4849331A (en) * 1987-06-09 1989-07-18 Life Technologies, Inc. Human papillomavirus 44 nucleic acid hybridization probes and methods for employing the same
US4908306A (en) * 1987-06-12 1990-03-13 Life Technologies, Inc. Human papillomavirus 56 nucleic acid hybridization probes and methods for employing the same
FR2629458B2 (fr) * 1987-07-31 1991-08-09 Ire Celltarg Sa Nouvelles sondes d'acides nucleiques specifiques de differents types de virus de papillome humain
EP0338067A4 (en) * 1987-10-02 1991-05-02 Microprobe Corporation Human papillomavirus type diagnosis with nucleotide probes
EP0408658A4 (en) * 1988-04-04 1991-10-02 Oncor, Inc. Human papilloma virus typing method and nucleic acid probes used therein
US5863717A (en) * 1989-11-03 1999-01-26 Abbott Laboratories Use of conserved oligonucleotide primers to amplify human papillomavirus DNA sequences

Also Published As

Publication number Publication date
EP0433396A1 (de) 1991-06-26
JPH04500910A (ja) 1992-02-20
DE68926507T2 (de) 1997-01-16
CA1339262C (en) 1997-08-12
US5283171A (en) 1994-02-01
US5182377A (en) 1993-01-26
WO1990002821A1 (en) 1990-03-22
AU645483B2 (en) 1994-01-20
EP0433396B1 (de) 1996-05-15
AU4401189A (en) 1990-04-02
JP2651483B2 (ja) 1997-09-10
ATE138108T1 (de) 1996-06-15

Similar Documents

Publication Publication Date Title
DE68926507D1 (de) Nachweis des humanen papillomavirus unter verwendung der polymerase-kettenreaktion
DE3853678T2 (de) Verfahren zum nachweis des karzinogenen menschlichen papillomavirus.
NZ218865A (en) Preparing samples for detecting of specific dna sequences
DE69233083T2 (de) Primers und Sondern zum Nachweis von Hepatitis C
DE58909587D1 (de) Verfahren zum Nachweis von gesplei ter mRNA
DE3751423T2 (de) Primers und Sonden zum Nachweis von Nukleinsäuren.
ATE164187T1 (de) Verfahren zum nachweis htlvi- und htlvii-viren mittels hybridizierung
DE69121821T2 (de) Nukleotid-Sequenzen nützlich als typenspezifische Sonden, PCR Primers und LCR Sonden zur Amplifikation und zum Nachweis von humanem Papillomavirus, sowie dazu verwendete Kits und Verfahren
DE50009139D1 (de) Multiplex-pcr zum nachweis von ehec-infektionen
ATE197481T1 (de) Verfahren und reagenzien zur typisierung von hla- genen der klasse i
Nolde et al. Development of an ALU-based realtime PCR assay for the quantitation of genomic (human) DNA
Manos et al. Detection of human papillomavirus by the polymerase chain reaction

Legal Events

Date Code Title Description
8364 No opposition during term of opposition