DE69003568D1 - Arzneimittel mit verzoegerter freigabe. - Google Patents

Arzneimittel mit verzoegerter freigabe.

Info

Publication number
DE69003568D1
DE69003568D1 DE90301065T DE69003568T DE69003568D1 DE 69003568 D1 DE69003568 D1 DE 69003568D1 DE 90301065 T DE90301065 T DE 90301065T DE 69003568 T DE69003568 T DE 69003568T DE 69003568 D1 DE69003568 D1 DE 69003568D1
Authority
DE
Germany
Prior art keywords
delayed release
medicinal products
medicinal
products
delayed
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE90301065T
Other languages
English (en)
Other versions
DE69003568T2 (de
Inventor
Herman J Eichel
Brent D Massmann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kinaform Technology Inc
Original Assignee
Kinaform Technology Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kinaform Technology Inc filed Critical Kinaform Technology Inc
Publication of DE69003568D1 publication Critical patent/DE69003568D1/de
Application granted granted Critical
Publication of DE69003568T2 publication Critical patent/DE69003568T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5084Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs
DE90301065T 1989-04-03 1990-02-01 Arzneimittel mit verzögerter Freigabe. Expired - Fee Related DE69003568T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/332,154 US5026559A (en) 1989-04-03 1989-04-03 Sustained-release pharmaceutical preparation

Publications (2)

Publication Number Publication Date
DE69003568D1 true DE69003568D1 (de) 1993-11-04
DE69003568T2 DE69003568T2 (de) 1994-02-10

Family

ID=23296943

Family Applications (1)

Application Number Title Priority Date Filing Date
DE90301065T Expired - Fee Related DE69003568T2 (de) 1989-04-03 1990-02-01 Arzneimittel mit verzögerter Freigabe.

Country Status (9)

Country Link
US (1) US5026559A (de)
EP (1) EP0391518B1 (de)
JP (1) JPH02289512A (de)
AR (1) AR244088A1 (de)
AU (1) AU622526B2 (de)
DD (1) DD299946A5 (de)
DE (1) DE69003568T2 (de)
HU (1) HU214576B (de)
MX (1) MX166703B (de)

Families Citing this family (113)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5540945A (en) * 1989-05-11 1996-07-30 Chugai Seiyaku Kabushiki Kaisha Pharmaceutical preparations for oral administration that are adapted to release the drug at appropriate sites in the intestines
IT1246382B (it) * 1990-04-17 1994-11-18 Eurand Int Metodo per la cessione mirata e controllata di farmaci nell'intestino e particolarmente nel colon
US5188836A (en) * 1990-07-27 1993-02-23 Warner-Lambert Company Sustained release formulations
US20040072757A1 (en) * 1990-09-04 2004-04-15 Cor Therapeutics, Inc. Agents affecting thrombosis and hemostasis
GB9104854D0 (en) * 1991-03-07 1991-04-17 Reckitt & Colmann Prod Ltd Sustained release compositions
NZ242065A (en) * 1991-03-26 1996-06-25 Csl Ltd Delayed release implant having a degradable or rupturable polymeric coating
US5225202A (en) * 1991-09-30 1993-07-06 E. R. Squibb & Sons, Inc. Enteric coated pharmaceutical compositions
US5968551A (en) * 1991-12-24 1999-10-19 Purdue Pharma L.P. Orally administrable opioid formulations having extended duration of effect
NZ253999A (en) * 1992-08-05 1996-07-26 Faulding F H & Co Ltd Pelletised substained release medicament
US5376384A (en) * 1992-12-23 1994-12-27 Kinaform Technology, Inc. Delayed, sustained-release pharmaceutical preparation
US5650156A (en) * 1993-02-22 1997-07-22 Vivorx Pharmaceuticals, Inc. Methods for in vivo delivery of nutriceuticals and compositions useful therefor
US5439686A (en) * 1993-02-22 1995-08-08 Vivorx Pharmaceuticals, Inc. Methods for in vivo delivery of substantially water insoluble pharmacologically active agents and compositions useful therefor
US5916596A (en) * 1993-02-22 1999-06-29 Vivorx Pharmaceuticals, Inc. Protein stabilized pharmacologically active agents, methods for the preparation thereof and methods for the use thereof
US5665382A (en) * 1993-02-22 1997-09-09 Vivorx Pharmaceuticals, Inc. Methods for the preparation of pharmaceutically active agents for in vivo delivery
US5997904A (en) * 1993-02-22 1999-12-07 American Bioscience, Inc. Total nutrient admixtures as stable multicomponent liquids or dry powders and methods for the preparation thereof
CA2155947C (en) * 1993-02-22 2007-08-21 Mark W. Grinstaff Methods for in vivo delivery of biologics and compositions useful therefor
US6528067B1 (en) 1993-02-22 2003-03-04 American Bioscience, Inc. Total nutrient admixtures as stable multicomponent liquids or dry powders and methods for the preparation thereof
US6753006B1 (en) 1993-02-22 2004-06-22 American Bioscience, Inc. Paclitaxel-containing formulations
US5382435A (en) * 1993-03-24 1995-01-17 Southwest Research Institute Microparticulate pharmaceutical delivery system
US6028190A (en) 1994-02-01 2000-02-22 The Regents Of The University Of California Probes labeled with energy transfer coupled dyes
SI0723436T1 (en) * 1994-07-08 2002-02-28 Astrazeneca Ab Multiple unit tableted dosage form i
SE9500422D0 (sv) * 1995-02-06 1995-02-06 Astra Ab New oral pharmaceutical dosage forms
US6166024A (en) 1995-03-30 2000-12-26 Mayo Foundation For Medical Education And Research Use of topical azathioprine and thioguanine to treat colorectal adenomas
SE9600071D0 (sv) 1996-01-08 1996-01-08 Astra Ab New oral formulation of two active ingredients I
SE512835C2 (sv) * 1996-01-08 2000-05-22 Astrazeneca Ab Doseringsform innehållande en mångfald enheter alla inneslutande syralabil H+K+ATPas-hämmare
SE9600072D0 (sv) * 1996-01-08 1996-01-08 Astra Ab New oral formulation of two active ingredients II
SE9600070D0 (sv) 1996-01-08 1996-01-08 Astra Ab New oral pharmaceutical dosage forms
US5776490A (en) * 1996-01-26 1998-07-07 The Center For Innovative Technology Complex protein-walled microcapsules containing lipid-walled microcapsules and method for producing same
US5656746A (en) * 1996-03-28 1997-08-12 The Proctor & Gamble Company Temporary wet strength polymers from oxidized reaction product of polyhydroxy polymer and 1,2-disubstituted carboxylic alkene
US5698688A (en) * 1996-03-28 1997-12-16 The Procter & Gamble Company Aldehyde-modified cellulosic fibers for paper products having high initial wet strength
US8071128B2 (en) 1996-06-14 2011-12-06 Kyowa Hakko Kirin Co., Ltd. Intrabuccally rapidly disintegrating tablet and a production method of the tablets
US8828432B2 (en) 1996-10-28 2014-09-09 General Mills, Inc. Embedding and encapsulation of sensitive components into a matrix to obtain discrete controlled release particles
DK0946145T3 (da) * 1996-12-20 2008-12-15 Mcneil Ppc Inc Antitussive lægemidler afgivet af ionbytterharpikser
EP0951278A2 (de) * 1997-01-03 1999-10-27 ELAN CORPORATION, Plc Minitablette formulierung zur verzögerte freigabe von cisapride
WO1999048372A1 (en) 1998-03-23 1999-09-30 General Mills, Inc. Encapsulation of components into edible products
US7201923B1 (en) 1998-03-23 2007-04-10 General Mills, Inc. Encapsulation of sensitive liquid components into a matrix to obtain discrete shelf-stable particles
UA69413C2 (uk) 1998-05-22 2004-09-15 Брістол-Майерс Сквібб Компані Фармацевтична композиція, яка містить серцевину та ентеросолюбільну оболонку, фармацевтична композиція у вигляді сфероїдальних гранул, спосіб одержання сфероїдальних гранул та спосіб одержання фармацевтичної композиції
US7122207B2 (en) * 1998-05-22 2006-10-17 Bristol-Myers Squibb Company High drug load acid labile pharmaceutical composition
UA73092C2 (uk) * 1998-07-17 2005-06-15 Брістол-Майерс Сквібб Компані Таблетка з ентеросолюбільним покриттям і спосіб її приготування
US6524620B2 (en) 1998-07-20 2003-02-25 Andrx Pharmaceuticals, Inc. Diltiazem controlled release formulation and method of manufacture
EP0978275A1 (de) * 1998-08-05 2000-02-09 Pharma Pass SA, Les Scientifiques Feste pharmazeutische Dosierungsform mit kontrollierten Wirkstofffreisetzung
US6126967A (en) * 1998-09-03 2000-10-03 Ascent Pediatrics Extended release acetaminophen particles
US6139875A (en) * 1998-09-29 2000-10-31 Eastman Chemical Company Aqueous enteric coating composition and low gastric permeability enteric coating
AU753476B2 (en) * 1998-11-25 2002-10-17 Cima Labs, Inc. Taste masking rapid release coating system
NZ517465A (en) 1999-09-02 2003-10-31 Nostrum Pharmaceuticals Inc Controlled release pellet formulation
US7138143B1 (en) 1999-09-30 2006-11-21 Otsuka Pharmaceutical Company, Limited Coated preparation soluble in the lower digestive tract
US6500463B1 (en) 1999-10-01 2002-12-31 General Mills, Inc. Encapsulation of sensitive components into a matrix to obtain discrete shelf-stable particles
DE19952586A1 (de) * 1999-11-02 2001-07-12 Deotexis Inc Mikrokapselsystem zur umweltinduzierten Abgabe von Wirkstoffen
US7838037B2 (en) * 1999-11-17 2010-11-23 Tagra Biotechnologies Ltd. Method of microencapsulation
US6627223B2 (en) * 2000-02-11 2003-09-30 Eurand Pharmaceuticals Ltd. Timed pulsatile drug delivery systems
GB0007419D0 (en) 2000-03-27 2000-05-17 Smithkline Beecham Gmbh Composition
US6468568B1 (en) 2000-06-16 2002-10-22 General Mills, Inc. Oligosaccharide encapsulated mineral and vitamin ingredients
US6436453B1 (en) 2000-06-16 2002-08-20 General Mills, Inc. Production of oil encapsulated minerals and vitamins in a glassy matrix
US6558718B1 (en) 2000-06-19 2003-05-06 General Mills, Inc. Nutrient clusters for food products and methods of preparation
JP2004537338A (ja) * 2001-03-02 2004-12-16 ユーロ−セルティーク,エス.エイ. 個別の投与剤形を調合するための方法と装置
DE60232290D1 (de) 2001-04-09 2009-06-25 Rohm & Haas Kontrollierte Auflösung von Wirkstoffen
US20020176842A1 (en) * 2001-04-09 2002-11-28 Lyn Hughes Extended release of active ingredients
GB2374874A (en) * 2001-04-11 2002-10-30 Bioprogress Tech Int Inc Modified cellulose films
US20030099711A1 (en) * 2001-08-29 2003-05-29 David Meadows Sustained release preparations
US6500454B1 (en) * 2001-10-04 2002-12-31 Eurand Pharmaceuticals Ltd. Timed, sustained release systems for propranolol
US9358214B2 (en) * 2001-10-04 2016-06-07 Adare Pharmaceuticals, Inc. Timed, sustained release systems for propranolol
US8101209B2 (en) 2001-10-09 2012-01-24 Flamel Technologies Microparticulate oral galenical form for the delayed and controlled release of pharmaceutical active principles
US6663888B2 (en) * 2001-12-14 2003-12-16 Eurand Pharmaceuticals Ltd. Pulsatile release histamine H2 antagonist dosage form
US20050025824A1 (en) * 2001-12-14 2005-02-03 Eurand Pharmaceuticals Ltd. Pulsatile release histamine H2 antagonist dosage form
US7022342B2 (en) 2002-03-28 2006-04-04 Andrx Corporation, Inc. Controlled release oral dosage form of beta-adrenergic blocking agents
CN100577164C (zh) 2002-04-09 2010-01-06 弗拉梅技术公司 可改进释放阿莫西林的微囊含水混悬液形式的口服药物制剂
IL164222A0 (en) 2002-04-09 2005-12-18 Flamel Tech Sa Oral pharmaceutical formulation in the form of aqueous suspension for modified release of active principle(s)
US7431986B2 (en) 2002-07-24 2008-10-07 General Mills, Inc. Encapsulation of sensitive components using pre-emulsification
MY142204A (en) * 2002-07-25 2010-10-29 Pharmacia Corp Pramipexole once-daily dosage form
US20050226926A1 (en) 2002-07-25 2005-10-13 Pfizer Inc Sustained-release tablet composition of pramipexole
GB0221986D0 (en) * 2002-09-21 2002-10-30 Bioprogress Technology Ltd Films with improved barrier properties
WO2004056337A2 (en) * 2002-12-18 2004-07-08 Pain Therapeutics Oral dosage forms with therapeutically active agents in controlled release cores and immediate release gelatin capsule coats
US8367111B2 (en) 2002-12-31 2013-02-05 Aptalis Pharmatech, Inc. Extended release dosage forms of propranolol hydrochloride
AR045068A1 (es) * 2003-07-23 2005-10-12 Univ Missouri Formulacion de liberacion inmediata de composiciones farmaceuticas
WO2005032525A1 (en) * 2003-10-03 2005-04-14 Lifecycle Pharma A/S A method for preparing modified release pharmaceutical compositions
US20050181050A1 (en) * 2004-01-28 2005-08-18 Collegium Pharmaceutical, Inc. Dosage forms using drug-loaded ion exchange resins
US8007827B2 (en) * 2004-04-02 2011-08-30 Impax Laboratories, Inc. Pharmaceutical dosage forms having immediate release and/or controlled release properties
US20050265955A1 (en) * 2004-05-28 2005-12-01 Mallinckrodt Inc. Sustained release preparations
UA88477C2 (ru) * 2004-08-13 2009-10-26 Бёрингер Ингельхайм Интернациональ Гмбх Композиция пеллеты пролонгированного высвобождения, которая содержит прамипексол или его фармацевтически приемлемую соль, способ ее изготовления и ее применение
ME01316B (me) * 2004-08-13 2013-12-20 Boehringer Ingelheim Int Formulacija tablete sa produženim oslobađanjem koji sadrži pramipeksol ili njegovu farmaceutski prihvatljivu so
US8747895B2 (en) * 2004-09-13 2014-06-10 Aptalis Pharmatech, Inc. Orally disintegrating tablets of atomoxetine
US20060062845A1 (en) * 2004-09-17 2006-03-23 Cimex Pharma Ag Alfuzosin tablets and synthesis
US8758814B2 (en) * 2004-10-08 2014-06-24 Mcneil-Ppc, Inc. Chewable enteric coated aspirin tablets
US9884014B2 (en) 2004-10-12 2018-02-06 Adare Pharmaceuticals, Inc. Taste-masked pharmaceutical compositions
NZ728442A (en) 2004-10-21 2018-05-25 Adare Pharmaceuticals Inc Taste-masked pharmaceutical compositions with gastrosoluble pore-formers
US20060105038A1 (en) * 2004-11-12 2006-05-18 Eurand Pharmaceuticals Limited Taste-masked pharmaceutical compositions prepared by coacervation
CA2596035A1 (en) * 2005-01-28 2006-08-03 Collegium Pharmaceutical, Inc. Non-ionic non-aqueous vehicles for topical and oral administration of carrier-complexed active agents
US9161918B2 (en) 2005-05-02 2015-10-20 Adare Pharmaceuticals, Inc. Timed, pulsatile release systems
FR2886150B1 (fr) * 2005-05-24 2007-08-24 Flamel Technologies Sa Forme pharmaceutique orale a base d'au moins un principe actif dont la solubilite varie en fonction des conditions de ph gastrique
WO2007009012A2 (en) * 2005-07-13 2007-01-18 Al Czap Compositions for oral administration of sustained release glutathione, methods for their production and uses thereof
CA2924200C (en) * 2005-10-12 2017-09-05 Proventiv Therapeutics, Llc Methods and articles for treating 25-hydroxyvitamin d insufficiency and deficiency
US7803413B2 (en) 2005-10-31 2010-09-28 General Mills Ip Holdings Ii, Llc. Encapsulation of readily oxidizable components
SI1993559T1 (sl) 2006-02-03 2017-01-31 Opko Renal, Llc Zdravljenje nezadostnosti in pomanjkanja vitamina D s 25-hidroksivitaminon D2 in 25-hidroksivitaminom D3
JP2009526021A (ja) * 2006-02-10 2009-07-16 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 放出を加減した製剤
US20090098202A1 (en) * 2006-02-10 2009-04-16 Boehringer Ingelheim International Gmbh Extended Release Formulation
HUE037309T2 (hu) 2006-06-21 2018-08-28 Opko Ireland Global Holdings Ltd Terápia D-vitamin telítési szer alkalmazásával és D-vitamin hormon helyettesítõ szer
US20080187579A1 (en) * 2007-02-01 2008-08-07 Pavan Bhat Extended-release dosage form
WO2008134523A1 (en) 2007-04-25 2008-11-06 Proventiv Therapeutics, Llc Method of safely and effectively treating and preventing secondary hyperparathyroidism in chronic kidney disease
KR101495578B1 (ko) * 2007-04-25 2015-02-25 사이토크로마 인코포레이티드 비타민 d 부족 및 결핍의 치료 방법
PT3342405T (pt) 2007-04-25 2019-12-02 Opko Ireland Global Holdings Ltd Libertação controlada 25-hidroxivitamina d
EP2148685A4 (de) * 2007-04-25 2010-07-28 Cytochroma Inc Verfahren und verbindungen für die vitamin-d-therapie
US20090196935A1 (en) * 2008-02-01 2009-08-06 Ahmed Salah U Pharmaceutical Capsules Comprising Extended Release Dipyridamole Pellets
EP3112476B1 (de) 2008-04-02 2023-08-02 EirGen Pharma Ltd. Verfahren, zusammensetzungen, verwendungen und kits für vitamin-d-mangel und verwandten erkrankungen
US20100204121A1 (en) * 2009-02-10 2010-08-12 Romero Augustin T Dietary supplements containing terpenoid acids of maslinic acid or oleanolic acid and process for enhancing muscle mass in mammals
NZ600256A (en) 2009-12-02 2014-05-30 Aptalis Pharma Ltd Fexofenadine microcapsules and compositions containing them
RS60087B1 (sr) 2010-03-29 2020-05-29 Opko Ireland Global Holdings Ltd Postupci i kompozicije za snižavanje nivoa paratireoidnog hormona
KR101847947B1 (ko) 2013-03-15 2018-05-28 옵코 아이피 홀딩스 Ⅱ 인코포레이티드 안정화되고 변형된 비타민 d 방출 제형
CN106604733A (zh) 2014-08-07 2017-04-26 欧普科爱尔兰环球控股有限公司 利用25‑羟基维生素d的辅助疗法
AU2015311637B2 (en) * 2014-09-06 2019-07-18 Integral Biosystems Llc Methods and biocompatible compositions to achieve sustained drug release in the eye
WO2016205701A1 (en) 2015-06-19 2016-12-22 University Of Southern California Enteral fast access tract platform system
US10631564B2 (en) 2015-06-19 2020-04-28 University Of Southern California Enterically coated microparticle compositions and methods for modified nutrient delivery
MY198547A (en) 2016-03-28 2023-09-04 Opko Ireland Global Holdings Ltd Methods of vitamin d treatment
WO2022124914A1 (en) 2020-12-08 2022-06-16 Ruminant Biotech Corp Limited Improvements to devices and methods for delivery of substances to animals

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3115441A (en) * 1962-06-06 1963-12-24 Victor M Hermelin Timed release pharmaceutical preparations and method of making the same
US3155590A (en) * 1962-08-02 1964-11-03 Ncr Co Encapsulation process and its product
US3341416A (en) * 1963-12-11 1967-09-12 Ncr Co Encapsulation of aspirin in ethylcellulose and its product
US3531418A (en) * 1965-08-18 1970-09-29 Ncr Co En masse encapsulation process
US3488418A (en) * 1965-11-18 1970-01-06 Sterling Drug Inc Sustained relief analgesic composition
US3492397A (en) * 1967-04-07 1970-01-27 Warner Lambert Pharmaceutical Sustained release dosage in the pellet form and process thereof
US4025613A (en) * 1971-07-19 1977-05-24 Richard G. Powers Timed-release aspirin
JPS5411687A (en) * 1977-06-28 1979-01-27 Oki Electric Ind Co Ltd Manufacture for semiconductor integrated circuit
JPS5937870B2 (ja) * 1980-01-31 1984-09-12 富士通株式会社 半導体不揮発性記憶装置
JPS5867616A (ja) * 1981-10-15 1983-04-22 Tanabe Seiyaku Co Ltd 腸溶性マイクロカプセル
DK150008C (da) * 1981-11-20 1987-05-25 Benzon As Alfred Fremgangsmaade til fremstilling af et farmaceutisk oralt polydepotpraeparat
DK151608C (da) * 1982-08-13 1988-06-20 Benzon As Alfred Fremgangsmaade til fremstilling af et farmaceutisk peroralt polydepotpraeparat med kontrolleret afgivelse
DE3233764A1 (de) * 1982-09-11 1984-03-15 R.P. Scherer GmbH, 6930 Eberbach Verfahren zur herstellung oraler dosierungseinheiten
US4520009A (en) * 1983-11-28 1985-05-28 Verex Laboratories, Inc. Sustained released aspirin formulation
US4728512A (en) * 1985-05-06 1988-03-01 American Home Products Corporation Formulations providing three distinct releases
DE3678644D1 (de) * 1985-08-16 1991-05-16 Procter & Gamble Wirkstoffpartikel mit sowohl kontinuierlicher als auch schneller freisetzung.
EP0212745B1 (de) * 1985-08-16 1991-04-10 The Procter & Gamble Company Partikel mit konstanter Wirkstofffreisetzung
AU591248B2 (en) * 1986-03-27 1989-11-30 Kinaform Technology, Inc. Sustained-release pharaceutical preparation
US4752470A (en) * 1986-11-24 1988-06-21 Mehta Atul M Controlled release indomethacin
US4808413A (en) * 1987-04-28 1989-02-28 E. R. Squibb & Sons, Inc. Pharmaceutical compositions in the form of beadlets and method
DE3812799A1 (de) * 1988-04-16 1989-10-26 Sanol Arznei Schwarz Gmbh Oral zu verabreichende pharmazeutische zubereitung mit kontrollierter wirkstofffreisetzung und verfahren zu deren herstellung

Also Published As

Publication number Publication date
HUT74088A (en) 1996-11-28
HU900583D0 (en) 1990-04-28
MX166703B (es) 1993-01-28
US5026559A (en) 1991-06-25
AR244088A1 (es) 1993-10-29
EP0391518B1 (de) 1993-09-29
DD299946A5 (de) 1992-05-14
HU214576B (hu) 1998-04-28
JPH02289512A (ja) 1990-11-29
AU5079290A (en) 1990-10-04
EP0391518A3 (de) 1991-05-08
AU622526B2 (en) 1992-04-09
DE69003568T2 (de) 1994-02-10
EP0391518A2 (de) 1990-10-10

Similar Documents

Publication Publication Date Title
DE69003568D1 (de) Arzneimittel mit verzoegerter freigabe.
DE3782840D1 (de) Arzneimittel mit verzoegerter freigabe.
DE3684446D1 (de) Arzneimittel mit verzoegerter stossweiser freisetzung.
DE69004214D1 (de) Arzneimittel mit verzögerter freisetzung und ph-gesteuerten membranüberzügen.
DE69018647D1 (de) Arzneimittel.
DE3686275D1 (de) Praeparate mit verzoegerter freisetzung.
DE3780223T2 (de) Arzneimittel mit gesteuerter freisetzung.
NO903001D0 (no) Fremgangsmaate for fremstilling av farmasoeytiske preparater med forlenget frigivelse.
DE69115229T2 (de) Arzneimittel.
DE3775483D1 (de) Zubereitung mit verzoegerter freigabe.
DE3778106D1 (de) Dosierungsform mit verzoegernder freisetzung.
DE69224656T2 (de) Arzneimittel
ATE285774T1 (de) Ranolazinhaltige arzneimittel mit verzögerter wirkstoffabgabe
ATE92309T1 (de) Matrix-zubereitungen mit verzoegerter freisetzung.
DE59003337D1 (de) Pressling mit retardierter Wirkstofffreisetzung.
DE68908354D1 (de) Verpackung fuer arzneimittel.
DE3881208T2 (de) Schädlinge abweisende Mikrokapseln mit verzögerter Abgabe.
DE69006963T2 (de) Stark absorbierbares Arzneimittel.
DE69214310D1 (de) Pranoprofen enthaltendes Arzneimittel mit verzögerter Wirkstoffabgabe
DE68907392D1 (de) Dysmnesie modifizierende arzneimittel.
ATE219365T1 (de) Arzneimittel enthaltend mizolastin mit verzögerter wirkstoffabgabe
ATE127690T1 (de) Niedrigdosiertes aspirin mit gesteuerter freigabe.
FI902993A0 (fi) Kompositprodukt baserad pao mineralfiber foer producering av utpressade stycken.
DE3887237D1 (de) Arzneimittel.
DE3790958T1 (de) Arzneimittel mit oestrogener wirkung

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee