DE69008727D1 - Orale osmotische vorrichtung mit einem hydrogel als treibendes teil. - Google Patents

Orale osmotische vorrichtung mit einem hydrogel als treibendes teil.

Info

Publication number
DE69008727D1
DE69008727D1 DE69008727T DE69008727T DE69008727D1 DE 69008727 D1 DE69008727 D1 DE 69008727D1 DE 69008727 T DE69008727 T DE 69008727T DE 69008727 T DE69008727 T DE 69008727T DE 69008727 D1 DE69008727 D1 DE 69008727D1
Authority
DE
Germany
Prior art keywords
wall
agent
delivered
drug
hydrophilic polymer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69008727T
Other languages
English (en)
Other versions
DE69008727T2 (de
Inventor
Brian Barclay
Jerry Childers
Jeri Wright
Virgil Place
Patrick Wong
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alza Corp
Original Assignee
Alza Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alza Corp filed Critical Alza Corp
Application granted granted Critical
Publication of DE69008727D1 publication Critical patent/DE69008727D1/de
Publication of DE69008727T2 publication Critical patent/DE69008727T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0002Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0004Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
DE69008727T 1989-07-14 1990-07-11 Orale osmotische vorrichtung mit einem hydrogel als treibendes teil. Expired - Fee Related DE69008727T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/380,229 US5021053A (en) 1989-07-14 1989-07-14 Oral osmotic device with hydrogel driving member
PCT/US1990/003882 WO1991001130A1 (en) 1989-07-14 1990-07-11 Oral osmotic device with hydrogel driving member

Publications (2)

Publication Number Publication Date
DE69008727D1 true DE69008727D1 (de) 1994-06-09
DE69008727T2 DE69008727T2 (de) 1994-08-18

Family

ID=23500397

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69008727T Expired - Fee Related DE69008727T2 (de) 1989-07-14 1990-07-11 Orale osmotische vorrichtung mit einem hydrogel als treibendes teil.

Country Status (18)

Country Link
US (2) US5021053A (de)
EP (1) EP0482075B1 (de)
JP (1) JPH05502215A (de)
KR (1) KR920703020A (de)
AT (1) ATE105182T1 (de)
AU (1) AU633340B2 (de)
CA (1) CA2020955C (de)
DE (1) DE69008727T2 (de)
DK (1) DK0482075T3 (de)
ES (1) ES2052263T3 (de)
FI (1) FI920164A0 (de)
GR (1) GR1000650B (de)
IE (1) IE62717B1 (de)
NO (1) NO915043L (de)
NZ (2) NZ234447A (de)
PT (1) PT94664B (de)
WO (1) WO1991001130A1 (de)
ZA (1) ZA905429B (de)

Families Citing this family (60)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5776493A (en) * 1989-07-14 1998-07-07 Alza Corporation Oral osmotic device for delivery of nystatin with hydrogel driving member
DK0540623T3 (da) * 1990-07-23 1995-03-20 Alza Corp Oral osmotisk indretning til afgivelse af nikotin
US5147654A (en) * 1990-07-23 1992-09-15 Alza Corporation Oral osmotic device for delivering nicotine
US5575995A (en) * 1991-08-15 1996-11-19 Giovanoni; Richard L. Ferric subsulfate gel and methods of using same
US5340581A (en) * 1991-08-23 1994-08-23 Gillette Canada, Inc. Sustained-release matrices for dental application
US5254349A (en) * 1991-12-06 1993-10-19 Alza Corporation Process for lessening irritation caused by drug
US5266332A (en) * 1991-12-06 1993-11-30 Alza Corporation Method for administering anti-Parkinson drug
US5200195A (en) * 1991-12-06 1993-04-06 Alza Corporation Process for improving dosage form delivery kinetics
US5200194A (en) * 1991-12-18 1993-04-06 Alza Corporation Oral osmotic device
US5294770A (en) * 1992-01-14 1994-03-15 Alza Corporation Laser tablet treatment system with dual access to tablet
US5248310A (en) * 1992-03-27 1993-09-28 Alza Corporation Oral osmotic device with hydrogel driving member
US5512299A (en) * 1992-03-30 1996-04-30 Alza Corporation Method of treating oral inflammatory disease
US5294433A (en) * 1992-04-15 1994-03-15 The Procter & Gamble Company Use of H-2 antagonists for treatment of gingivitis
EP0659077A1 (de) * 1992-07-02 1995-06-28 TheraTech, Inc. Pilocarpin-abgabesystem mit kontrollierter freisetzung
US5661171A (en) * 1992-07-02 1997-08-26 Oramed, Inc. Controlled release pilocarpine delivery system
US5512293A (en) * 1992-07-23 1996-04-30 Alza Corporation Oral sustained release drug delivery device
US5573776A (en) * 1992-12-02 1996-11-12 Alza Corporation Oral osmotic device with hydrogel driving member
US5368588A (en) * 1993-02-26 1994-11-29 Bettinger; David S. Parenteral fluid medication reservoir pump
DE4313928C2 (de) * 1993-04-28 1996-09-19 Lohmann Therapie Syst Lts Transdermales therapeutisches System zur kontrollierten Abgabe von Pilocarpin an die Haut, Verfahren zu seiner Herstellung und seine Verwendung
US5460826A (en) * 1994-06-27 1995-10-24 Alza Corporation Morphine therapy
US5914131A (en) * 1994-07-07 1999-06-22 Alza Corporation Hydromorphone therapy
US5529787A (en) * 1994-07-07 1996-06-25 Alza Corporation Hydromorphone therapy
US5681568A (en) * 1994-08-19 1997-10-28 Cambridge Neuroscience, Inc. Device for delivery of substances and methods of use thereof
US6491945B1 (en) * 1994-09-16 2002-12-10 Alza Corporation Hydrocodone therapy
US5827180A (en) * 1994-11-07 1998-10-27 Lifemasters Supported Selfcare Method and apparatus for a personal health network
US5658474A (en) * 1994-12-16 1997-08-19 Alza Corporation Method and apparatus for forming dispenser delivery ports
US5656284A (en) * 1995-04-24 1997-08-12 Balkin; Michael S. Oral transmucosal delivery tablet and method of making it
US5713852A (en) * 1995-06-07 1998-02-03 Alza Corporation Oral dosage and method for treating painful conditions of the oral cavity
FR2737661B1 (fr) * 1995-08-08 1997-10-31 Mgi Pharma Inc Composition pharmaceutique sous forme de comprimes comprenant du chlorhydrate de pilocarpine
DK0914097T3 (da) * 1996-03-12 2002-04-29 Alza Corp Sammensætning og doseringsform omfattende opioid antagonist
US5948787A (en) * 1997-02-28 1999-09-07 Alza Corporation Compositions containing opiate analgesics
US6284262B1 (en) 1999-01-26 2001-09-04 Virgil A. Place Compact dosage unit for buccal administration of a pharmacologically active agent
US6319510B1 (en) 1999-04-20 2001-11-20 Alayne Yates Gum pad for delivery of medication to mucosal tissues
US6562375B1 (en) 1999-08-04 2003-05-13 Yamanouchi Pharmaceuticals, Co., Ltd. Stable pharmaceutical composition for oral use
US6491683B1 (en) * 1999-09-07 2002-12-10 Alza Corporation Osmotic dosage form composed of an extruded polymer tube form
US6242003B1 (en) 2000-04-13 2001-06-05 Novartis Ag Organic compounds
US20060127474A1 (en) * 2001-04-11 2006-06-15 Oskar Kalb Pharmaceutical compositions comprising fluvastatin
US20030035839A1 (en) * 2001-05-15 2003-02-20 Peirce Management, Llc Pharmaceutical composition for both intraoral and oral administration
US6863901B2 (en) * 2001-11-30 2005-03-08 Collegium Pharmaceutical, Inc. Pharmaceutical composition for compressed annular tablet with molded triturate tablet for both intraoral and oral administration
US6827946B2 (en) * 2001-12-05 2004-12-07 Collegium Pharmaceutical, Inc. Compositions containing both sedative and non-sedative antihistamines
US7328706B2 (en) 2002-05-06 2008-02-12 Dynamic Mouth Devices Llc Therapeutic and protective dental device useful as an intra-oral delivery system
AU2003275190A1 (en) * 2002-09-18 2004-04-08 Medtronic Vascular, Inc. Controllable drug releasing gradient coatings for medical devices
AU2003270778B2 (en) 2002-09-20 2009-10-08 Alpharma Pharmaceuticals, Llc Sequestering subunit and related compositions and methods
US7276246B2 (en) * 2003-05-09 2007-10-02 Cephalon, Inc. Dissolvable backing layer for use with a transmucosal delivery device
US7306812B2 (en) * 2003-05-09 2007-12-11 Cephalon, Inc. Dissolvable backing layer for use with a transmucosal delivery device
WO2005030181A1 (en) * 2003-09-26 2005-04-07 Alza Corporation Controlled release formulations of opioid and nonopioid analgesics
MXPA06003453A (es) * 2003-09-26 2006-08-31 Johnson & Johnson Barra de empuje oros para el suministro controlado de agentes activos.
NZ546148A (en) 2003-09-26 2009-05-31 Alza Corp Drug coating providing high drug loading and methods for providing the same
WO2005030182A1 (en) * 2003-09-26 2005-04-07 Alza Corporation Controlled release formulations exhibiting an ascending rate of release
US8541026B2 (en) * 2004-09-24 2013-09-24 Abbvie Inc. Sustained release formulations of opioid and nonopioid analgesics
US20070048347A1 (en) 2005-08-26 2007-03-01 Laura Bardach Intra-oral device for treating obesity
MX2008016372A (es) 2006-06-19 2009-05-28 Alpharma Inc Composiciones farmaceuticas.
US20080207593A1 (en) * 2007-02-28 2008-08-28 Collegium Pharmaceutical, Inc. Antihistamine Combination
US8623418B2 (en) 2007-12-17 2014-01-07 Alpharma Pharmaceuticals Llc Pharmaceutical composition
US8956654B2 (en) 2009-06-02 2015-02-17 Dow Global Technologies Llc Sustained release dosage form
US10575976B2 (en) 2015-04-30 2020-03-03 Dynamic Mouth Devices, L.L.C. Method and apparatus for weight management utilizing an intra-oral device
CA2984494A1 (en) 2015-05-06 2016-11-10 Synagile Corporation Pharmaceutical suspensions containing drug particles, devices for their administration, and methods of their use
CN106344535B (zh) * 2016-08-29 2019-09-20 济南康和医药科技有限公司 一种氟伐他汀钠微孔渗透泵控释片及其制备方法
US10758329B1 (en) 2019-08-20 2020-09-01 Raymond L. Wright, III Hydrating mouth guard
US11529310B2 (en) 2020-12-08 2022-12-20 Ruminant Biotech Corp Limited Devices and methods for delivery of substances to animals

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3402240A (en) * 1957-06-25 1968-09-17 Pfizer & Co C Medicinal tablet and process of making same
US3054724A (en) * 1960-05-12 1962-09-18 Smith Kline French Lab Coloring discrete solids and compositions therefor
US3732865A (en) * 1971-01-13 1973-05-15 Alza Corp Osmotic dispenser
US3845770A (en) * 1972-06-05 1974-11-05 Alza Corp Osmatic dispensing device for releasing beneficial agent
US3916899A (en) * 1973-04-25 1975-11-04 Alza Corp Osmotic dispensing device with maximum and minimum sizes for the passageway
US4111202A (en) * 1976-11-22 1978-09-05 Alza Corporation Osmotic system for the controlled and delivery of agent over time
US4238475A (en) * 1979-08-01 1980-12-09 Life Savers Inc. Chewing cum capable of releasing finely divided water-insoluble materials therefrom
US4327725A (en) * 1980-11-25 1982-05-04 Alza Corporation Osmotic device with hydrogel driving member
GB2122892B (en) * 1982-07-02 1986-01-29 Squibb & Sons Inc Nystantin pastille formulation
CA1208558A (en) * 1982-10-07 1986-07-29 Kazuo Kigasawa Soft buccal
US4612008A (en) * 1983-05-11 1986-09-16 Alza Corporation Osmotic device with dual thermodynamic activity
US4783337A (en) * 1983-05-11 1988-11-08 Alza Corporation Osmotic system comprising plurality of members for dispensing drug
US4749575A (en) * 1983-10-03 1988-06-07 Bio-Dar Ltd. Microencapsulated medicament in sweet matrix
US4639368A (en) * 1984-08-23 1987-01-27 Farmacon Research Corporation Chewing gum containing a medicament and taste maskers
US4627971A (en) * 1985-04-22 1986-12-09 Alza Corporation Osmotic device with self-sealing passageway
US4666705A (en) * 1985-06-03 1987-05-19 E. R. Squibb & Sons, Inc. Controlled release formulation
US4713243A (en) * 1986-06-16 1987-12-15 Johnson & Johnson Products, Inc. Bioadhesive extruded film for intra-oral drug delivery and process
JPS63188621A (ja) * 1987-01-30 1988-08-04 Taisho Pharmaceut Co Ltd 矯味経口製剤
US4983394A (en) * 1990-05-03 1991-01-08 Warner-Lambert Company Flavor enhancing and medicinal taste masking agent

Also Published As

Publication number Publication date
NZ243890A (en) 1993-03-26
DE69008727T2 (de) 1994-08-18
US5021053A (en) 1991-06-04
ES2052263T3 (es) 1994-07-01
ZA905429B (en) 1991-04-24
CA2020955C (en) 2000-10-31
PT94664B (pt) 1997-09-30
DK0482075T3 (da) 1994-08-15
GR900100531A (en) 1991-12-10
ATE105182T1 (de) 1994-05-15
WO1991001130A1 (en) 1991-02-07
AU6047690A (en) 1991-02-22
NZ234447A (en) 1993-03-26
FI920164A0 (fi) 1992-01-14
GR1000650B (el) 1992-09-11
IE902525A1 (en) 1991-02-13
CA2020955A1 (en) 1991-01-15
NO915043D0 (no) 1991-12-20
EP0482075B1 (de) 1994-05-04
US5053032A (en) 1991-10-01
KR920703020A (ko) 1992-12-17
JPH05502215A (ja) 1993-04-22
PT94664A (pt) 1991-04-18
NO915043L (no) 1992-01-13
EP0482075A1 (de) 1992-04-29
AU633340B2 (en) 1993-01-28
IE62717B1 (en) 1995-02-22

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee