DE69009743T2 - Dosierungsform für dauerverabreichung. - Google Patents

Dosierungsform für dauerverabreichung.

Info

Publication number
DE69009743T2
DE69009743T2 DE69009743T DE69009743T DE69009743T2 DE 69009743 T2 DE69009743 T2 DE 69009743T2 DE 69009743 T DE69009743 T DE 69009743T DE 69009743 T DE69009743 T DE 69009743T DE 69009743 T2 DE69009743 T2 DE 69009743T2
Authority
DE
Germany
Prior art keywords
allergen extract
multiphasic
allergen
sustained release
microcapsules
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69009743T
Other languages
English (en)
Other versions
DE69009743D1 (de
Inventor
Loui J Silvestri
Ruth H Pyle
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biosearch Inc
Original Assignee
Biosearch Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biosearch Inc filed Critical Biosearch Inc
Application granted granted Critical
Publication of DE69009743D1 publication Critical patent/DE69009743D1/de
Publication of DE69009743T2 publication Critical patent/DE69009743T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)
DE69009743T 1989-02-08 1990-02-08 Dosierungsform für dauerverabreichung. Expired - Fee Related DE69009743T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/308,225 US4990336A (en) 1989-02-08 1989-02-08 Sustained release dosage form
PCT/US1990/000750 WO1990009166A1 (en) 1989-02-08 1990-02-08 Sustained release dosage form

Publications (2)

Publication Number Publication Date
DE69009743D1 DE69009743D1 (de) 1994-07-14
DE69009743T2 true DE69009743T2 (de) 1994-11-03

Family

ID=23193090

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69009743T Expired - Fee Related DE69009743T2 (de) 1989-02-08 1990-02-08 Dosierungsform für dauerverabreichung.

Country Status (8)

Country Link
US (1) US4990336A (de)
EP (1) EP0457834B1 (de)
AT (1) ATE106716T1 (de)
AU (1) AU5109190A (de)
DE (1) DE69009743T2 (de)
DK (1) DK0457834T3 (de)
ES (1) ES2057537T3 (de)
WO (1) WO1990009166A1 (de)

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US5206023A (en) * 1991-01-31 1993-04-27 Robert F. Shaw Method and compositions for the treatment and repair of defects or lesions in cartilage
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US5674534A (en) * 1992-06-11 1997-10-07 Alkermes, Inc. Composition for sustained release of non-aggregated erythropoietin
US5716644A (en) * 1992-06-11 1998-02-10 Alkermes, Inc. Composition for sustained release of non-aggregated erythropoietin
DE69332222T3 (de) * 1992-06-11 2007-05-10 Alkermes Controlled Therapeutics, Inc., Cambridge Enythropoietin enthaltendes arzneimittelabgabesystem
US5643595A (en) * 1992-11-24 1997-07-01 Alkermes Controlled Therapeutics Inc. Ii Growth promoters for animals
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CA2172508C (en) * 1993-10-22 2005-08-23 Jeffrey L. Cleland Method for preparing microspheres comprising a fluidized bed drying step
US6913767B1 (en) 1993-10-25 2005-07-05 Genentech, Inc. Compositions for microencapsulation of antigens for use as vaccines
US6080429A (en) * 1993-10-25 2000-06-27 Genentech, Inc. Method for drying microspheres
US5643605A (en) * 1993-10-25 1997-07-01 Genentech, Inc. Methods and compositions for microencapsulation of adjuvants
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US5540927A (en) * 1995-04-12 1996-07-30 Monsanto Company Microencapsulation process by coacervation
US6265389B1 (en) 1995-08-31 2001-07-24 Alkermes Controlled Therapeutics, Inc. Microencapsulation and sustained release of oligonucleotides
EP0850051A2 (de) * 1995-08-31 1998-07-01 Alkermes Controlled Therapeutics, Inc. Mittel zur verzögerten freisetzung eines wirkstoffs
US6074673A (en) * 1996-04-22 2000-06-13 Guillen; Manuel Slow-release, self-absorbing, drug delivery system
US5762943A (en) * 1996-05-14 1998-06-09 Ribi Immunochem Research, Inc. Methods of treating type I hypersensitivity using monophosphoryl lipid A
EP1690531A3 (de) * 1996-09-30 2010-01-20 Alza Corporation Dosierungsform und Verfahren zur Verabreichung von einem Wirkstoff
US5952226A (en) * 1996-11-05 1999-09-14 Modex Therapeutiques Hypoxia responsive EPO producing cells
US6919373B1 (en) 1996-11-12 2005-07-19 Alza Corporation Methods and devices for providing prolonged drug therapy
US6465425B1 (en) 2000-02-10 2002-10-15 Alkermes Controlled Therapeutics, Inc. Microencapsulation and sustained release of biologically active acid-stable or free sulfhydryl-containing proteins
FR2822709B1 (fr) * 2001-03-30 2007-01-19 Antialis Composition pharmaceutique anti-allergique comprenant au moins un allergene et au moins un compose antihistaminique
FR2822708A1 (fr) * 2001-03-30 2002-10-04 Antialis Composition pharmaceutique anti-allergique comprenant au moins un allergene et au moins un compose antihistaminique
US7858093B1 (en) * 2004-10-29 2010-12-28 Iowa State University Research Foundation, Inc. Controlled-release immunogenic formulations to modulate immune response

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Also Published As

Publication number Publication date
ATE106716T1 (de) 1994-06-15
DK0457834T3 (da) 1994-10-31
ES2057537T3 (es) 1994-10-16
EP0457834A1 (de) 1991-11-27
AU5109190A (en) 1990-09-05
DE69009743D1 (de) 1994-07-14
WO1990009166A1 (en) 1990-08-23
EP0457834B1 (de) 1994-06-08
EP0457834A4 (en) 1992-01-22
US4990336A (en) 1991-02-05

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee