DE69022297D1 - DNS und ihre Verwendung. - Google Patents

DNS und ihre Verwendung.

Info

Publication number
DE69022297D1
DE69022297D1 DE69022297T DE69022297T DE69022297D1 DE 69022297 D1 DE69022297 D1 DE 69022297D1 DE 69022297 T DE69022297 T DE 69022297T DE 69022297 T DE69022297 T DE 69022297T DE 69022297 D1 DE69022297 D1 DE 69022297D1
Authority
DE
Germany
Prior art keywords
pacap38
dna
protein
protective group
preparing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69022297T
Other languages
English (en)
Other versions
DE69022297T2 (de
Inventor
Haruo Onda
Akira Arimura
Ciharu Kimura
Chieko Kitada
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tulane University
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP02039841A external-priority patent/JP3034894B2/ja
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Application granted granted Critical
Publication of DE69022297D1 publication Critical patent/DE69022297D1/de
Publication of DE69022297T2 publication Critical patent/DE69022297T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/57563Vasoactive intestinal peptide [VIP]; Related peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
DE69022297T 1989-06-20 1990-06-19 DNS und ihre Verwendung. Expired - Fee Related DE69022297T2 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP15579189 1989-06-20
JP25992489 1989-10-06
JP28477189 1989-11-02
JP02039841A JP3034894B2 (ja) 1989-06-20 1990-02-22 新規dnaおよびその用途

Publications (2)

Publication Number Publication Date
DE69022297D1 true DE69022297D1 (de) 1995-10-19
DE69022297T2 DE69022297T2 (de) 1996-02-22

Family

ID=27460824

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69022297T Expired - Fee Related DE69022297T2 (de) 1989-06-20 1990-06-19 DNS und ihre Verwendung.

Country Status (5)

Country Link
US (2) US5198542A (de)
EP (1) EP0404034B1 (de)
AT (1) ATE127844T1 (de)
CA (1) CA2019363C (de)
DE (1) DE69022297T2 (de)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2077764C (en) * 1990-03-17 2002-12-10 Nobuhiro Suzuki Antibody to pacap and use thereof
AU651596B2 (en) * 1990-06-05 1994-07-28 Immunex Corporation Type II interleukin-1 receptors
EP0467279A3 (en) * 1990-07-18 1992-08-05 Takeda Chemical Industries, Ltd. Polypeptides having c-amp producing activity
US5521069A (en) * 1990-08-10 1996-05-28 Takeda Chemical Industries, Ltd. Genomic DNA exons having exons encoding human pituitary adenylate cyclase activity peptide with 38 amino acids residues(PACAP38) and a promoter thereof
EP0470604A3 (en) * 1990-08-10 1992-12-09 Takeda Chemical Industries, Ltd. Pacap38, proteine with adenylate cyclase activity
US5623050A (en) * 1991-08-22 1997-04-22 Takeda Chemical Industries, Ltd. Stable polypeptides having c-AMP production enhancing activity and the use thereof
US5695954A (en) * 1993-05-14 1997-12-09 University Of Victoria Innovation & Development Corporation DNA encoding two fish neuropeptides
US6680295B1 (en) * 1994-09-22 2004-01-20 The Administrators Of The Tulane Educational Fund Method and pharmaceutical composition for prevention and treatment of brain damage
JPH10505863A (ja) * 1994-09-22 1998-06-09 ジ・アドミニストレーターズ・オブ・ザ・チューレン・エデュケイショナル・ファンド 脳障害の予防および治療のための方法および医薬組成物
US6165755A (en) * 1997-01-23 2000-12-26 University Of Victoria Innovation And Development Corporation Chicken neuropeptide gene useful for improved poultry production
AU3469699A (en) * 1998-04-03 1999-10-25 Millennium Pharmaceuticals, Inc. Methods and compositions for the diagnosis and treatment of neuropsychiatric disorders
EP1423509A2 (de) * 2001-08-30 2004-06-02 Stem Cell Therapeutics Inc. Differenzierung von neuralen stammzellen und therapeutische anwendung
EP1430114B1 (de) * 2001-09-14 2012-01-18 Stem Cell Therapeutics Inc. Prolaktin-induzierte zunahme an neuronalen stammzellen und dessen therapeutische anwendung
WO2003024471A2 (en) * 2001-09-18 2003-03-27 Stem Cell Therapeutics Inc. Effect of growth hormone and igf-1 on neural stem cells and therapeutic application
AU2003250697B2 (en) * 2002-07-30 2008-05-01 Stem Cell Therapeutics Inc. Oligodendrocyte production from multipotent neural stem cells
WO2004011497A1 (en) * 2002-07-31 2004-02-05 Stem Cell Therapeutics Inc. Method of enhancing neural stem cell proliferation, differentiation, and survival using pituitary adenylate cyclase activating polypeptide (pacap)
ES2320754T3 (es) * 2002-10-22 2009-05-28 Waratah Pharmaceuticals, Inc. Tratamiento de la diabetes.
JP4990634B2 (ja) * 2004-02-13 2012-08-01 ステム セル セラピューティクス コーポレイション 神経幹細胞の増殖および神経発生のための黄体化ホルモン(LH)、および絨毛性ゴナドトロピン(hCG)の使用
EP1778268B1 (de) 2004-07-21 2016-05-04 Tulane University Health Sciences Center Behandlung von nierenfehlfunktion und multiplem myelom mithilfe von pacap-verbindungen
JP2008515818A (ja) * 2004-10-07 2008-05-15 ステム セル セラピューティクス コーポレイション 妊娠に関連する化合物の投与による多能性幹細胞の増殖の刺激
CA2664629A1 (en) 2005-09-27 2007-04-05 Christopher Gregg Oligodendrocyte precursor cell proliferation regulated by prolactin
WO2007106986A1 (en) * 2006-03-17 2007-09-27 Stem Cell Therapeutics Corp. Dosing regimes for lh or hcg and epo for treatment of neurological disorders
WO2011054001A2 (en) 2009-11-02 2011-05-05 The Administrators Of The Tulane Analogs of pitutary adenylate cyclase-activating polypeptide (pacap) and methods for their use
EP3283517A4 (de) 2015-04-16 2019-03-06 Alder Biopharmaceuticals, Inc. Anti-pacap-antikörper und verwendungen davon
US10202435B2 (en) 2016-04-15 2019-02-12 Alder Biopharmaceuticals, Inc. Anti-PACAP antibodies and uses thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4939224A (en) * 1987-02-26 1990-07-03 The Salk Institute Biotechnology/Industrial Associates, Inc. Vasoactive intestinal peptide analogs
US5128242A (en) * 1989-06-19 1992-07-07 The Administrators Of The Tulane Educational Fund Hypothalamic polypeptides with adenylate cyclase stimulating activity

Also Published As

Publication number Publication date
EP0404034A3 (de) 1991-07-17
CA2019363A1 (en) 1990-12-20
DE69022297T2 (de) 1996-02-22
ATE127844T1 (de) 1995-09-15
EP0404034A2 (de) 1990-12-27
EP0404034B1 (de) 1995-09-13
CA2019363C (en) 2000-05-30
US5198542A (en) 1993-03-30
US5326860A (en) 1994-07-05

Similar Documents

Publication Publication Date Title
ATE127844T1 (de) Dns und ihre verwendung.
ATE140965T1 (de) Protein, dna und ihre verwendung
ATE149524T1 (de) Dns, die ein menschliches, gefässverengendes peptid kodiert, und dessen verwendung
DE68914582T2 (de) Endothelin-DNA und ihre Verwendung.
ATE209679T1 (de) Proteine mit faktor viii aktivität, verfahren zu deren herstellung unter verwendung von genetisch modifizierten zellen und diese enthaltende zusammensetzungen
DE69018920T2 (de) Verwendung von dns-fragmenten, die ein signalpeptid kodieren zur sekretion von reifen proteinen in rekombinanten hefen, expressions-kassetten, transformierte hefen und verfahren zur herstellung dieser proteine.
DE3785864D1 (de) Verfahren zur herstellung von menschlichem epidermalwachstumsfaktor und dessen analogen.
IL97758A0 (en) Epithelins:cysteine-rich growth modulating proteins
ATE135577T1 (de) Verwendung von buspiron zur herstellung eines pharmazeutischen präparats zur behandlung der alkoholsucht
DE69131069T2 (de) Plasmid das für die aminosäuresequenz von tcf-ii kodierende dns enthalt, transformierte zelle und produktion einer physiologisch aktiven substanz mit ihrer verwendung
DE69333346T2 (de) Neuartiges p- selectin ligandenprotein
PT92603A (pt) Processo de producao de factor de crescimento transformante, quimerico,beta
YU179489A (en) Process for preparing new derivatives of human/cattle basis fibroblast growth factor
DE69012377D1 (de) Polypeptid und dessen Herstellung.
EP0251730A3 (de) Herstellung von menschlichem Lysozym
ES2012128A6 (es) Metodo de tratar plantas con acidos organicos que contienen azufre.
DE3854420D1 (de) Onkogen kodierendes polypeptid, das wachstumsfaktoraktivität besitzt, verfahren zu seiner herstellung und verwendung.
EP0315118A3 (de) Endothelin kodierendes DNA und dessen Verwendung
AU1090688A (en) Synthetic porcine growth hormone
EP0241136A3 (de) Humaner, Klasse 1 Heparin bindender, Wachstumsfaktor
ATE154611T1 (de) Neuer megakaryokytischer koloniestimulierender faktor und verfahren zur herstellung
EP0191869A4 (de) Fisch-kalzitoninabkömmling und dessen herstellung und gensystem dafür.
EP0446361A4 (en) Polypeptide, production thereof, and pharmaceutical composition and cosmetic containing said polypeptide
EP0249854A3 (de) Polypeptid
IT1207443B (it) Macchina per falciare l'erba nelle scoline anche in presenza di colture.

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: TAKEDA CHEMICAL INDUSTRIES, LTD., OSAKA, JP THE AD

8327 Change in the person/name/address of the patent owner

Owner name: THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND,

8339 Ceased/non-payment of the annual fee