DE69025058T2 - Verfahren zur bestimmung von glukose in vollblut sowie gefäss und fotometer zur durchführung dieses verfahrens - Google Patents

Verfahren zur bestimmung von glukose in vollblut sowie gefäss und fotometer zur durchführung dieses verfahrens

Info

Publication number
DE69025058T2
DE69025058T2 DE69025058T DE69025058T DE69025058T2 DE 69025058 T2 DE69025058 T2 DE 69025058T2 DE 69025058 T DE69025058 T DE 69025058T DE 69025058 T DE69025058 T DE 69025058T DE 69025058 T2 DE69025058 T2 DE 69025058T2
Authority
DE
Germany
Prior art keywords
sample
pct
reagent
glucose
cavity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69025058T
Other languages
English (en)
Other versions
DE69025058D1 (de
Inventor
Jan Lilja
Sven-Erik Nilsson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
MIGRATA UK Ltd
Original Assignee
MIGRATA UK Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by MIGRATA UK Ltd filed Critical MIGRATA UK Ltd
Application granted granted Critical
Publication of DE69025058D1 publication Critical patent/DE69025058D1/de
Publication of DE69025058T2 publication Critical patent/DE69025058T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/54—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving glucose or galactose
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01—Arrangements or apparatus for facilitating the optical investigation
    • G01N21/03—Cuvette constructions
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/31—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
    • G01N21/314—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry with comparison of measurements at specific and non-specific wavelengths
    • G01N2015/011—
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01—Arrangements or apparatus for facilitating the optical investigation
    • G01N21/03—Cuvette constructions
    • G01N2021/0321—One time use cells, e.g. integrally moulded
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01—Arrangements or apparatus for facilitating the optical investigation
    • G01N21/03—Cuvette constructions
    • G01N2021/0325—Cells for testing reactions, e.g. containing reagents
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01—Arrangements or apparatus for facilitating the optical investigation
    • G01N21/03—Cuvette constructions
    • G01N2021/0346—Capillary cells; Microcells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/31—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
    • G01N21/314—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry with comparison of measurements at specific and non-specific wavelengths
    • G01N2021/3181—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry with comparison of measurements at specific and non-specific wavelengths using LEDs
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N21/78—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00—Features of devices classified in G01N21/00
    • G01N2201/12—Circuits of general importance; Signal processing
    • G01N2201/122—Kinetic analysis; determining reaction rate
    • G01N2201/1222—Endpoint determination; reaction time determination
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00—Features of devices classified in G01N21/00
    • G01N2201/12—Circuits of general importance; Signal processing
    • G01N2201/126—Microprocessor processing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/493—Physical analysis of biological material of liquid biological material urine
DE69025058T 1989-04-25 1990-04-24 Verfahren zur bestimmung von glukose in vollblut sowie gefäss und fotometer zur durchführung dieses verfahrens Expired - Lifetime DE69025058T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE8901514A SE466157B (sv) 1989-04-25 1989-04-25 Saett att bestaemma glukoshalten hos helblod samt engaangskuvett foer detta
PCT/SE1990/000273 WO1990012890A1 (en) 1989-04-25 1990-04-24 Method for determination of glucose in whole blood and cuvette and photometer for carrying out said method

Publications (2)

Publication Number Publication Date
DE69025058D1 DE69025058D1 (de) 1996-03-07
DE69025058T2 true DE69025058T2 (de) 1996-05-30

Family

ID=20375801

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69025058T Expired - Lifetime DE69025058T2 (de) 1989-04-25 1990-04-24 Verfahren zur bestimmung von glukose in vollblut sowie gefäss und fotometer zur durchführung dieses verfahrens

Country Status (18)

Country Link
US (1) US5866349A (de)
EP (1) EP0469097B1 (de)
JP (1) JPH0734758B2 (de)
KR (1) KR960004040B1 (de)
AT (1) ATE133453T1 (de)
AU (1) AU632569B2 (de)
BR (1) BR9007340A (de)
CA (1) CA2053284C (de)
DE (1) DE69025058T2 (de)
DK (1) DK0469097T3 (de)
ES (1) ES2081987T3 (de)
FI (1) FI102192B (de)
LT (1) LT3187B (de)
LV (1) LV10121B (de)
NO (1) NO300854B1 (de)
RU (1) RU2050545C1 (de)
SE (1) SE466157B (de)
WO (1) WO1990012890A1 (de)

Families Citing this family (50)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4935346A (en) * 1986-08-13 1990-06-19 Lifescan, Inc. Minimum procedure system for the determination of analytes
SE520341C2 (sv) 1998-01-14 2003-06-24 Hemocue Ab Metod och förfarande för blandning i ett tunt vätskeskick
US6458326B1 (en) 1999-11-24 2002-10-01 Home Diagnostics, Inc. Protective test strip platform
RU2157994C1 (ru) * 1999-12-30 2000-10-20 Институт молекулярной биологии им. В.А. Энгельгардта РАН Способ проведения клинического и биохимического анализа биологических жидкостей и устройство для его осуществления (варианты)
US6485923B1 (en) 2000-02-02 2002-11-26 Lifescan, Inc. Reagent test strip for analyte determination having hemolyzing agent
SE518539C2 (sv) * 2000-06-28 2002-10-22 Migrata U K Ltd Sätt och kyvett för kvantitativ hemoglobinbestämning i outspätt helblod
US6562625B2 (en) * 2001-02-28 2003-05-13 Home Diagnostics, Inc. Distinguishing test types through spectral analysis
US6541266B2 (en) 2001-02-28 2003-04-01 Home Diagnostics, Inc. Method for determining concentration of an analyte in a test strip
US6525330B2 (en) 2001-02-28 2003-02-25 Home Diagnostics, Inc. Method of strip insertion detection
US6586195B1 (en) 2001-11-19 2003-07-01 R.E. Davis Chemical Corporation Method of detecting sugars
SE0104443D0 (sv) * 2001-12-28 2001-12-28 Hemocue Ab Analysis method and cuvette therefor
CA2446368C (en) * 2002-10-29 2014-10-14 Bayer Healthcare Llc Diffuse reflectance readhead
EP1936356A1 (de) * 2002-10-29 2008-06-25 Bayer HealthCare LLC Diffuser Reflexionslesekopf
US6900058B2 (en) * 2003-03-11 2005-05-31 Bionostics, Inc. Control solution for photometric analysis
EP1714147B1 (de) * 2004-02-06 2014-07-23 Bayer HealthCare LLC Flüssigkeitstestsensor mit öffnungen zur steuerung des flüssigkeitsstroms
JP4128160B2 (ja) 2004-06-30 2008-07-30 三洋電機株式会社 混合比検出装置の制御方法
JP2008523413A (ja) 2004-12-13 2008-07-03 バイエル・ヘルスケア・エルエルシー 体液中の検体の測定に使用する透過分光システム
WO2006065899A1 (en) 2004-12-13 2006-06-22 Bayer Healthcare Llc A method of differentiating between blood and control solutions containing a common analyte
US20060281187A1 (en) 2005-06-13 2006-12-14 Rosedale Medical, Inc. Analyte detection devices and methods with hematocrit/volume correction and feedback control
WO2007041244A2 (en) 2005-09-30 2007-04-12 Intuity Medical, Inc. Multi-site body fluid sampling and analysis cartridge
SE531041C2 (sv) * 2006-07-17 2008-11-25 Hemocue Ab Räkning av trombocyter
US7797987B2 (en) * 2006-10-11 2010-09-21 Bayer Healthcare Llc Test sensor with a side vent and method of making the same
WO2008057479A2 (en) * 2006-11-07 2008-05-15 Bayer Healthcare Llc Method of making an auto-calibrating test sensor
WO2008076212A1 (en) * 2006-12-13 2008-06-26 Bayer Healthcare Llc Biosensor with coded information and method for manufacturing the same
US20080248581A1 (en) 2007-04-06 2008-10-09 Bayer Healthcare Llc Method for performing correction of blood glucose assay bias using blood hemoglobin concentration
EP2174129A1 (de) * 2007-08-06 2010-04-14 Bayer Healthcare, LLC System und verfahren zur automatischen kalibrierung
WO2009050177A1 (en) * 2007-10-15 2009-04-23 Ima Life S.R.L. Inline measurement of moving containers with infrared (ir) spectroscopy
US8241488B2 (en) 2007-11-06 2012-08-14 Bayer Healthcare Llc Auto-calibrating test sensors
DE102008006245A1 (de) * 2008-01-25 2009-07-30 Nirlus Engineering Ag Verfahren zur nichtinvasiven, optischen Bestimmung der Temperatur eines Mediums
US20090205399A1 (en) * 2008-02-15 2009-08-20 Bayer Healthcare, Llc Auto-calibrating test sensors
US10542919B2 (en) 2008-03-25 2020-01-28 St. Louis Medical Devices, Inc. Method and system for non-invasive blood glucose detection utilizing spectral data of one or more components other than glucose
CN102988061B (zh) 2008-05-22 2015-04-01 密苏里大学董事会 用光谱数据分析进行无创的光学血糖检测的方法和系统
EP2293719B1 (de) 2008-05-30 2015-09-09 Intuity Medical, Inc. Schnittstelle zwischen einer Vorrichtung zur entnahme von Körperflüssigkeitsproben und der Entnahmestelle
CA2726067C (en) 2008-06-06 2020-10-20 Intuity Medical, Inc. Detection meter and mode of operation
EP2169384B1 (de) * 2008-09-30 2013-04-10 General Electric Company IR-Gassensor mit einem vereinfachten Strahlenteiler.
US8424763B2 (en) * 2008-10-07 2013-04-23 Bayer Healthcare Llc Method of forming an auto-calibration circuit or label
US8586911B2 (en) * 2008-10-21 2013-11-19 Bayer Healthcare Llc Optical readhead and method of using the same
EP2851676B1 (de) 2008-12-18 2016-12-28 Ascensia Diabetes Care Holdings AG Testsensor mit Gitter zur Bestimmung der Temperatur des Testsensors
US8919605B2 (en) 2009-11-30 2014-12-30 Intuity Medical, Inc. Calibration material delivery devices and methods
JP6096655B2 (ja) * 2010-03-22 2017-03-15 バイエル・ヘルスケア・エルエルシーＢａｙｅｒ ＨｅａｌｔｈＣａｒｅ ＬＬＣ バイオセンサのための残差補正
EP3750480B1 (de) 2011-08-03 2022-02-02 Intuity Medical, Inc. Vorrichtung zur entnahme von körperflüssigkeiten
RU2509297C1 (ru) * 2012-08-31 2014-03-10 Закрытое акционерное общество Научно-производственное предприятие "ТЕХНОМЕДИКА" Фотометрический анализатор с ячейкой для установки оптической наливной кюветы
DE102012018015B3 (de) * 2012-09-06 2013-12-05 Jenoptik Polymer Systems Gmbh Messmodul zur remissions-photometrischen Analyse und Verfahren zu dessen Herstellung
FR3038723B1 (fr) 2015-07-07 2019-06-14 Commissariat A L'energie Atomique Et Aux Energies Alternatives Procede d’estimation d’une quantite d’analyte dans un liquide
EP3428623B1 (de) 2016-03-08 2021-06-16 Terumo Kabushiki Kaisha Komponentenmessvorrichtung, komponentenmessverfahren und komponentenmessprogramm
FR3049062B1 (fr) 2016-03-17 2023-06-02 Commissariat Energie Atomique Procede de caracterisation d’un echantillon liquide comportant des particules
CA3044226C (en) * 2016-11-18 2022-07-12 Siemens Healthcare Diagnostics Inc. Multiple sequential wavelength measurement of a liquid assay
CN110476055A (zh) 2017-03-23 2019-11-19 泰尔茂株式会社 成分测定装置以及成分测定装置组
CN110609002A (zh) * 2018-12-29 2019-12-24 深圳迈瑞生物医疗电子股份有限公司 一种干扰检测方法及样本分析仪
CN110715923A (zh) * 2019-11-24 2020-01-21 天津市宝坻区人民医院 α-D-葡萄糖检测试剂盒

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2964974A (en) 1957-12-24 1960-12-20 Cemam Conord Sa Transmission means for clothes washing machines
US3642444A (en) * 1969-05-02 1972-02-15 Minnesota Mining & Mfg Analytical reagent and method for carbohydrate analysis in body fluids
US3615228A (en) * 1969-11-20 1971-10-26 Dow Chemical Co Glucose determination method employing orthotoluidine
CS164231B2 (de) * 1972-09-28 1975-11-07
SE399768B (sv) * 1975-09-29 1978-02-27 Lilja Jan E Kyvett for provtagning, blandning av, provet med ett reagensmedel och direkt utforande av, serskilt optisk, analys av det med reagensmedlet blandade provet
SE422115B (sv) * 1976-09-13 1982-02-15 Jan Evert Lilja Kyvett enligt patenkravet 1 i patentet 7510863-9
US4120755A (en) * 1977-04-28 1978-10-17 Beckman Instruments, Inc. Kinetic method for determination of glucose concentrations with glucose dehydrogenase
DE7801673U1 (de) 1978-01-20 1979-06-28 Siemens Ag, 1000 Berlin Und 8000 Muenchen Roentgendiagnostikgenerator
DE3303098A1 (de) * 1983-01-31 1984-08-02 Boehringer Mannheim Gmbh, 6800 Mannheim Verfahren und reagenz zur glucosebestimmung im haemolysierten blut
GB2138936B (en) * 1983-04-26 1986-09-10 Gen Electric Co Plc Optical sensor systems
US4637978A (en) 1983-10-28 1987-01-20 Eastman Kodak Company Assay for analysis of whole blood
US5112490A (en) * 1986-02-19 1992-05-12 Jon Turpen Sample filtration, separation and dispensing device
US4865813A (en) * 1986-07-07 1989-09-12 Leon Luis P Disposable analytical device
JPS6371653A (ja) * 1986-09-16 1988-04-01 Fuji Photo Film Co Ltd 全血希釈液
JPH0726960B2 (ja) * 1988-04-05 1995-03-29 富士写真フイルム株式会社 乾式全血分析要素

Also Published As

Publication number Publication date
RU2050545C1 (ru) 1995-12-20
KR960004040B1 (ko) 1996-03-25
US5866349A (en) 1999-02-02
JPH04504662A (ja) 1992-08-20
NO914182D0 (no) 1991-10-24
LV10121A (lv) 1994-05-10
CA2053284C (en) 2001-12-11
BR9007340A (pt) 1992-04-21
DK0469097T3 (da) 1996-02-19
AU5557690A (en) 1990-11-16
SE466157B (sv) 1992-01-07
FI915021A0 (fi) 1991-10-24
DE69025058D1 (de) 1996-03-07
SE8901514L (sv) 1990-10-26
EP0469097B1 (de) 1996-01-24
ATE133453T1 (de) 1996-02-15
NO300854B1 (no) 1997-08-04
LT3187B (en) 1995-03-27
JPH0734758B2 (ja) 1995-04-19
KR920701475A (ko) 1992-08-11
SE8901514D0 (sv) 1989-04-25
CA2053284A1 (en) 1990-10-26
LV10121B (en) 1995-02-20
NO914182L (no) 1991-10-24
AU632569B2 (en) 1993-01-07
FI102192B1 (fi) 1998-10-30
FI102192B (fi) 1998-10-30
WO1990012890A1 (en) 1990-11-01
LTIP276A (en) 1994-10-25
EP0469097A1 (de) 1992-02-05
ES2081987T3 (es) 1996-03-16

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