DE69029540T2 - Oxidative Denaturierung von Eiweissanalyten - Google Patents

Oxidative Denaturierung von Eiweissanalyten

Info

Publication number
DE69029540T2
DE69029540T2 DE69029540T DE69029540T DE69029540T2 DE 69029540 T2 DE69029540 T2 DE 69029540T2 DE 69029540 T DE69029540 T DE 69029540T DE 69029540 T DE69029540 T DE 69029540T DE 69029540 T2 DE69029540 T2 DE 69029540T2
Authority
DE
Germany
Prior art keywords
protein
protein analytes
oxidizing agent
oxidative denaturation
disulfide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69029540T
Other languages
English (en)
Other versions
DE69029540D1 (de
Inventor
James Elting
Heinz Koelbl
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Bayer Corp
Original Assignee
Bayer AG
Bayer Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG, Bayer Corp filed Critical Bayer AG
Application granted granted Critical
Publication of DE69029540D1 publication Critical patent/DE69029540D1/de
Publication of DE69029540T2 publication Critical patent/DE69029540T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57473—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving carcinoembryonic antigen, i.e. CEA
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5306—Improving reaction conditions, e.g. reduction of non-specific binding, promotion of specific binding
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
DE69029540T 1989-07-10 1990-07-06 Oxidative Denaturierung von Eiweissanalyten Expired - Fee Related DE69029540T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/377,680 US5061790A (en) 1989-07-10 1989-07-10 Oxidative denaturation of protein analytes

Publications (2)

Publication Number Publication Date
DE69029540D1 DE69029540D1 (de) 1997-02-13
DE69029540T2 true DE69029540T2 (de) 1997-05-07

Family

ID=23490110

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69029540T Expired - Fee Related DE69029540T2 (de) 1989-07-10 1990-07-06 Oxidative Denaturierung von Eiweissanalyten

Country Status (18)

Country Link
US (1) US5061790A (de)
EP (1) EP0407813B1 (de)
JP (1) JP2915970B2 (de)
KR (1) KR910003380A (de)
AT (1) ATE147167T1 (de)
AU (1) AU633115B2 (de)
CA (1) CA2019671C (de)
DE (1) DE69029540T2 (de)
DK (1) DK0407813T3 (de)
ES (1) ES2095847T3 (de)
FI (1) FI903464A0 (de)
GR (1) GR3022906T3 (de)
IE (1) IE902493A1 (de)
IL (1) IL94993A (de)
NO (1) NO902833L (de)
NZ (1) NZ234396A (de)
PT (1) PT94633B (de)
ZA (1) ZA905360B (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2740223B1 (fr) * 1995-10-19 1997-11-14 Commissariat Energie Atomique Procede de determination d'auto-anticorps revelateurs de complications pathologiques ; dans le serum sanguin, en particulier de diabetiques
US20030202980A1 (en) * 1995-12-29 2003-10-30 Caplan Michael J. Methods and reagents for decreasing clinical reaction to allergy
US7879977B2 (en) 1998-01-31 2011-02-01 University Of Arkansas Methods and reagents for decreasing clinical reaction to allergy
JP2002501748A (ja) 1998-01-31 2002-01-22 ユニバーシティ オブ アーカンソー アレルギー反応を減少させるための方法および試薬
GB9827845D0 (en) * 1998-12-17 1999-02-10 Scolab S A Immunoassay or proteins
US20050063994A1 (en) * 2000-04-06 2005-03-24 Caplan Michael J. Methods and reagents for decreasing clinical reaction to allergy
US8246945B2 (en) * 2000-04-06 2012-08-21 University Of Arkansas Methods and reagents for decreasing clinical reaction to allergy
ES2260078T3 (es) 2000-04-06 2006-11-01 Seer Pharmaceuticals, Llc. Sistema de administracion microbiana.
US6801270B2 (en) * 2000-06-26 2004-10-05 Reveo, Inc. Backlight for a liquid crystal display having high light-recycling efficiency
DE10054055A1 (de) * 2000-10-31 2002-05-23 Nmi Univ Tuebingen Verfahren zur Analyse von Proteinen
US7460960B2 (en) * 2002-05-10 2008-12-02 Epitome Biosystems, Inc. Proteome epitope tags and methods of use thereof in protein modification analysis
US7618788B2 (en) * 2002-05-10 2009-11-17 Millipore Corporation Proteome epitope tags and methods of use thereof in protein modification analysis
EP1631314B1 (de) * 2003-06-09 2011-08-03 Redox-Reactive Reagents L.L.C. Verfahren zur änderung der bindungsspezifität von plasmaproteinen durch oxidations-reduktionsreaktionen
US7892751B2 (en) * 2003-06-09 2011-02-22 Redox-Reactive Reagents Llc Method of detecting or diagnosing of a neurodegenerative disease or condition
US9557325B2 (en) * 2003-06-09 2017-01-31 Redox-Reactive Reagents Llc Method of altering the binding specificity of proteins by oxidation-reduction reactions
US7855057B2 (en) * 2006-03-23 2010-12-21 Millipore Corporation Protein splice variant/isoform discrimination and quantitative measurements thereof
CN101627306B (zh) * 2007-03-08 2014-02-05 霍夫曼-拉罗奇有限公司 Slim-1在心力衰竭评估中的用途
KR101322247B1 (ko) * 2007-09-06 2013-10-25 삼성전자주식회사 진공청소기용 흡입브러시 및 그 높이조절방법
US20090280474A1 (en) * 2008-05-08 2009-11-12 Abbott Laboratories Method for detecting a virus
US20130189707A1 (en) * 2010-01-26 2013-07-25 Svetlana Alexandrovna Sergeeva Method of determination of autoantibody level by means of enzyme immunoassay
CA2863635A1 (en) * 2012-02-02 2013-08-08 Perfinity Biosciences, Inc. Selector based recognition and quantification system and method for multiple analytes in a single analysis

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2448530C3 (de) * 1974-10-11 1980-03-27 Behringwerke Ag, 3550 Marburg Verfahren zum Herstellen von Derivaten des Diphtherietoxins und diese enthaltende Mittel
US4658022A (en) * 1985-08-08 1987-04-14 Molecular Diagnostics, Inc. Binding of antibody reagents to denatured protein analytes
US4683136A (en) * 1985-03-06 1987-07-28 Scripps Clinic And Research Foundation Proteinaceous antigens with conformation-independent and conformation-dependent determinants
US4713366A (en) * 1985-12-04 1987-12-15 The Ohio State University Research Foundation Antigenic modification of polypeptides

Also Published As

Publication number Publication date
CA2019671A1 (en) 1991-01-10
ZA905360B (en) 1991-04-24
AU5872790A (en) 1991-01-10
GR3022906T3 (en) 1997-06-30
ES2095847T3 (es) 1997-03-01
NO902833L (no) 1991-01-11
IL94993A0 (en) 1991-06-10
ATE147167T1 (de) 1997-01-15
JP2915970B2 (ja) 1999-07-05
KR910003380A (ko) 1991-02-27
FI903464A0 (fi) 1990-07-09
EP0407813A3 (en) 1992-11-25
NO902833D0 (no) 1990-06-26
DE69029540D1 (de) 1997-02-13
US5061790A (en) 1991-10-29
PT94633B (pt) 1997-04-30
JPH0368868A (ja) 1991-03-25
IL94993A (en) 1994-05-30
NZ234396A (en) 1992-02-25
CA2019671C (en) 2002-08-13
EP0407813B1 (de) 1997-01-02
EP0407813A2 (de) 1991-01-16
AU633115B2 (en) 1993-01-21
DK0407813T3 (da) 1997-06-16
IE902493A1 (en) 1991-02-13
PT94633A (pt) 1991-03-20

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee