DE69115471T2 - Gerät zur iontophoretischen verabreichung von medikamenten - Google Patents
Gerät zur iontophoretischen verabreichung von medikamentenInfo
- Publication number
- DE69115471T2 DE69115471T2 DE69115471T DE69115471T DE69115471T2 DE 69115471 T2 DE69115471 T2 DE 69115471T2 DE 69115471 T DE69115471 T DE 69115471T DE 69115471 T DE69115471 T DE 69115471T DE 69115471 T2 DE69115471 T2 DE 69115471T2
- Authority
- DE
- Germany
- Prior art keywords
- electrode element
- active
- active electrode
- layer
- hydrogel
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L33/00—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
- C08L33/02—Homopolymers or copolymers of acids; Metal or ammonium salts thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
- A61K9/0009—Galenical forms characterised by the drug release technique; Application systems commanded by energy involving or responsive to electricity, magnetism or acoustic waves; Galenical aspects of sonophoresis, iontophoresis, electroporation or electroosmosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/42—Use of materials characterised by their function or physical properties
- A61L15/60—Liquid-swellable gel-forming materials, e.g. super-absorbents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/0404—Electrodes for external use
- A61N1/0408—Use-related aspects
- A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
- A61N1/0432—Anode and cathode
- A61N1/044—Shape of the electrode
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/0404—Electrodes for external use
- A61N1/0408—Use-related aspects
- A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
- A61N1/0448—Drug reservoir
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09J—ADHESIVES; NON-MECHANICAL ASPECTS OF ADHESIVE PROCESSES IN GENERAL; ADHESIVE PROCESSES NOT PROVIDED FOR ELSEWHERE; USE OF MATERIALS AS ADHESIVES
- C09J133/00—Adhesives based on homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides, or nitriles thereof; Adhesives based on derivatives of such polymers
- C09J133/24—Homopolymers or copolymers of amides or imides
- C09J133/26—Homopolymers or copolymers of acrylamide or methacrylamide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/0404—Electrodes for external use
- A61N1/0408—Use-related aspects
- A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
- A61N1/0432—Anode and cathode
- A61N1/0436—Material of the electrode
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/0404—Electrodes for external use
- A61N1/0408—Use-related aspects
- A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
- A61N1/0444—Membrane
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L2666/00—Composition of polymers characterized by a further compound in the blend, being organic macromolecular compounds, natural resins, waxes or and bituminous materials, non-macromolecular organic substances, inorganic substances or characterized by their function in the composition
- C08L2666/02—Organic macromolecular compounds, natural resins, waxes or and bituminous materials
- C08L2666/04—Macromolecular compounds according to groups C08L7/00 - C08L49/00, or C08L55/00 - C08L57/00; Derivatives thereof
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US50284190A | 1990-03-30 | 1990-03-30 | |
US67531391A | 1991-03-26 | 1991-03-26 | |
PCT/US1991/002030 WO1991015260A1 (en) | 1990-03-30 | 1991-03-26 | Device and method for iontophoretic drug delivery |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69115471D1 DE69115471D1 (de) | 1996-01-25 |
DE69115471T2 true DE69115471T2 (de) | 1996-05-02 |
Family
ID=27054298
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69115471T Expired - Lifetime DE69115471T2 (de) | 1990-03-30 | 1991-03-26 | Gerät zur iontophoretischen verabreichung von medikamenten |
Country Status (12)
Country | Link |
---|---|
US (2) | US5423739A (de) |
EP (1) | EP0521988B1 (de) |
AT (1) | ATE131392T1 (de) |
AU (1) | AU657681B2 (de) |
CA (1) | CA2079315C (de) |
DE (1) | DE69115471T2 (de) |
DK (1) | DK0521988T3 (de) |
ES (1) | ES2082973T3 (de) |
FI (1) | FI924382A (de) |
IE (1) | IE74127B1 (de) |
NO (1) | NO923770L (de) |
PT (1) | PT97217B (de) |
Families Citing this family (93)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0521988B1 (de) * | 1990-03-30 | 1995-12-13 | Alza Corporation | Gerät zur iontophoretischen verabreichung von medikamenten |
AU1958295A (en) * | 1994-04-13 | 1995-11-10 | Novartis Ag | Temporally controlled drug delivery systems |
CA2154928C (en) * | 1994-08-19 | 2000-01-04 | Katherine Louise Mayer | Body fitting compound sanitary napkin |
JPH08155041A (ja) * | 1994-12-05 | 1996-06-18 | Advance Co Ltd | イオントフォレシス用新規高能率電極システム |
US5990179A (en) * | 1995-04-28 | 1999-11-23 | Alza Corporation | Composition and method of enhancing electrotransport agent delivery |
US6881208B1 (en) * | 1995-06-05 | 2005-04-19 | Joseph B. Phipps | Method and device for transdermal electrotransport delivery of fentanyl and sufentanil |
ZA964320B (en) * | 1995-06-05 | 1997-01-13 | Alza Corp | Device for transdermal electrotransport delivery of fentanyl and sufentanil |
US5840056A (en) * | 1995-06-15 | 1998-11-24 | Empi, Inc. | Iontophoresis electrode |
US5788666A (en) * | 1995-06-15 | 1998-08-04 | Empi, Inc. | Iontophoresis electrode |
US5989409A (en) * | 1995-09-11 | 1999-11-23 | Cygnus, Inc. | Method for glucose sensing |
EP0920345A4 (de) * | 1996-06-19 | 2006-05-10 | Vyteris Inc | Iontophoretische abscheidung von zelladhäsions-inhibitoren |
US5857993A (en) * | 1996-07-12 | 1999-01-12 | Empi, Inc. | Process of making an iontophoresis electrode |
US5871461A (en) * | 1996-07-12 | 1999-02-16 | Empi, Inc. | Method of making an iontophoresis electrode |
US5941843A (en) * | 1996-07-12 | 1999-08-24 | Empi, Inc. | Iontophoresis electrode |
US5797867A (en) * | 1996-09-27 | 1998-08-25 | Becton Dickinson And Company | Iontophoretic drug delivery system, including method for activating same for attachment to patient |
US6246904B1 (en) * | 1996-12-17 | 2001-06-12 | Alza Corporation | Electrotransport drug delivery reservoirs containing inert fillers |
WO1998028037A1 (en) | 1996-12-20 | 1998-07-02 | Alza Corporation | Device and method for enhancing transdermal agent flux |
US6139718A (en) | 1997-03-25 | 2000-10-31 | Cygnus, Inc. | Electrode with improved signal to noise ratio |
US6119036A (en) | 1997-03-26 | 2000-09-12 | The Board Of Regents Of The University Of Oklahoma | Iontophoretic transdermal delivery device |
CA2308489A1 (en) | 1997-10-09 | 1999-04-22 | Emory University | Method and devices for transdermal delivery of lithium |
US6918901B1 (en) | 1997-12-10 | 2005-07-19 | Felix Theeuwes | Device and method for enhancing transdermal agent flux |
JP2001525232A (ja) * | 1997-12-11 | 2001-12-11 | アルザ・コーポレーション | 経皮物質の流れを増強するための装置 |
AU739616B2 (en) * | 1997-12-11 | 2001-10-18 | Alza Corporation | Device for enhancing transdermal agent flux |
EP1911488A3 (de) | 1997-12-11 | 2008-12-03 | Alza Corporation | Vorrichtung zur Verstärkung des Flusses transdermaler Mittel |
EP1037687B8 (de) | 1997-12-11 | 2008-10-22 | Alza Corporation | Vorrichtung zur verbesserung des transdermalen flusses von medikamenten |
US6163720A (en) * | 1997-12-18 | 2000-12-19 | Alza Corporation | Layered rate controlling membranes for use in an electrotransport device |
US6096726A (en) | 1998-03-11 | 2000-08-01 | Surface Solutions Laboratories Incorporated | Multicomponent complex for use with substrate |
US6117296A (en) * | 1998-07-21 | 2000-09-12 | Thomson; Timothy | Electrically controlled contractile polymer composite |
US7662409B2 (en) * | 1998-09-25 | 2010-02-16 | Gel-Del Technologies, Inc. | Protein matrix materials, devices and methods of making and using thereof |
US20050147690A1 (en) * | 1998-09-25 | 2005-07-07 | Masters David B. | Biocompatible protein particles, particle devices and methods thereof |
WO2000047274A1 (en) | 1999-02-10 | 2000-08-17 | Gmp Drug Delivery, Inc. | Iontophoresis, electroporation and combination patches for local drug delivery |
DE60024312T2 (de) | 1999-12-10 | 2006-08-17 | Alza Corp., Mountain View | Transdermale Wirkstoffabgabe von makromolekularen Wirkstoffen und Vorrichtung hierfür |
WO2001060448A1 (en) | 2000-02-18 | 2001-08-23 | University Of Utah Research Foundation | Methods for extracting substances using alternating current |
US6512950B2 (en) | 2000-02-18 | 2003-01-28 | University Of Utah Research Foundation | Methods for delivering agents using alternating current |
WO2001076553A2 (en) * | 2000-04-06 | 2001-10-18 | Sontra Medical, Inc. | Method and device for enhanced transdermal drug delivery |
US7137975B2 (en) * | 2001-02-13 | 2006-11-21 | Aciont, Inc. | Method for increasing the battery life of an alternating current iontophoresis device using a barrier-modifying agent |
US7572288B2 (en) * | 2001-07-20 | 2009-08-11 | Microvention, Inc. | Aneurysm treatment device and method of use |
DE10141254C1 (de) * | 2001-08-23 | 2003-04-03 | Susann Edel | Iontophorese-Kaltkontaktelektrodensystem zur gleichzeitigen Anwendung der Kühlung und der Iontophorese |
CA2483778A1 (en) * | 2002-04-29 | 2003-11-13 | Gel-Del Technologies, Inc. | Biomatrix structural containment and fixation systems and methods of use thereof |
US20040015145A1 (en) * | 2002-07-16 | 2004-01-22 | The Procter & Gamble Company | Absorbent article having a graphic visible through body contacting surface |
WO2004032963A2 (en) * | 2002-10-04 | 2004-04-22 | Photokinetix Inc. | Photokinetic delivery of biologically active substances using pulsed incoherent light |
WO2004057057A1 (en) * | 2002-12-23 | 2004-07-08 | Council Of Scientific And Industrial Research | Process for manufacture of proton conductive polymer gel useful as backfill for sacrificial and impressed current anode systems |
US8465537B2 (en) * | 2003-06-17 | 2013-06-18 | Gel-Del Technologies, Inc. | Encapsulated or coated stent systems |
WO2005034852A2 (en) | 2003-08-26 | 2005-04-21 | Gel-Del Technologies, Inc. | Protein biomaterials and biocoacervates and methods of making and using thereof |
EP1691746B1 (de) * | 2003-12-08 | 2015-05-27 | Gel-Del Technologies, Inc. | Mukoadhäsive arzneimittelabgabevorrichtungen und verfahren zu ihrer herstellung und verwendung |
US20060135906A1 (en) * | 2004-11-16 | 2006-06-22 | Akihiko Matsumura | Iontophoretic device and method for administering immune response-enhancing agents and compositions |
JP2006296511A (ja) * | 2005-04-15 | 2006-11-02 | Transcutaneous Technologies Inc | 外用剤、外用剤の塗布方法、イオントフォレーシス装置及び経皮パッチ |
US8386030B2 (en) * | 2005-08-08 | 2013-02-26 | Tti Ellebeau, Inc. | Iontophoresis device |
US8295922B2 (en) | 2005-08-08 | 2012-10-23 | Tti Ellebeau, Inc. | Iontophoresis device |
US20070088332A1 (en) * | 2005-08-22 | 2007-04-19 | Transcutaneous Technologies Inc. | Iontophoresis device |
US20090254018A1 (en) * | 2005-08-24 | 2009-10-08 | Mizuo Nakayama | Electrode assembly for freezing-type iontophoresis device |
US20070048362A1 (en) * | 2005-08-29 | 2007-03-01 | Transcutaneous Technologies Inc. | General purpose electrolyte solution composition for iontophoresis |
JPWO2007032446A1 (ja) | 2005-09-15 | 2009-03-19 | Tti・エルビュー株式会社 | ロッド型イオントフォレーシス装置 |
JP2009509659A (ja) * | 2005-09-30 | 2009-03-12 | Tti・エルビュー株式会社 | 生体界面への活性物質の送達のイオントフォレーシス装置及び方法 |
WO2007041322A2 (en) * | 2005-09-30 | 2007-04-12 | Tti Ellebeau, Inc. | Iontophoretic delivery of active agents conjugated to nanoparticles |
KR20080066712A (ko) * | 2005-09-30 | 2008-07-16 | 티티아이 엘뷰 가부시키가이샤 | 관능화된 미세바늘 경피 약물 전달 시스템, 장치 및 방법 |
WO2007041323A1 (en) * | 2005-09-30 | 2007-04-12 | Tti Ellebeau, Inc. | Iontophoretic delivery of vesicle-encapsulated active agents |
KR20080080087A (ko) * | 2005-09-30 | 2008-09-02 | 티티아이 엘뷰 가부시키가이샤 | 신규 약학 담체를 이용한 경피 약물 전달시스템, 장치 및방법 |
JP2009509657A (ja) * | 2005-09-30 | 2009-03-12 | Tti・エルビュー株式会社 | 生体界面への活性物質の送達のイオントフォレーシス装置及び方法 |
WO2007041526A2 (en) * | 2005-09-30 | 2007-04-12 | Transcutaneous Technologies Inc. | Iontophoresis apparatus and method to deliver antibiotics to biological interfaces |
JP2009522011A (ja) * | 2005-12-30 | 2009-06-11 | Tti・エルビュー株式会社 | 活性物質を生体界面に送達するイオントフォレーシスシステム、装置及び方法 |
US20080004564A1 (en) * | 2006-03-30 | 2008-01-03 | Transcutaneous Technologies Inc. | Controlled release membrane and methods of use |
WO2008038241A2 (en) * | 2006-09-29 | 2008-04-03 | Koninklijke Philips Electronics N.V. | Electrically activated gel array for transdermal drug delivery |
US20080193514A1 (en) * | 2006-11-02 | 2008-08-14 | Transcu Ltd. | Compostions and methods for iontophoresis delivery of active ingredients through hair follicles |
EP2061551A2 (de) | 2006-12-01 | 2009-05-27 | TTI ellebeau, Inc. | Systeme, vorrichtungen und verfahren zum antrieb oder zur steuerung von geräten, z. b. geräten zur transdermalen verabreichung |
JPWO2008087803A1 (ja) * | 2007-01-16 | 2010-05-06 | 国立大学法人北海道大学 | 抗酸化成分を封入したイオントフォレーシス用リポソーム製剤 |
US8197844B2 (en) | 2007-06-08 | 2012-06-12 | Activatek, Inc. | Active electrode for transdermal medicament administration |
JP2010187707A (ja) * | 2007-06-12 | 2010-09-02 | Hokkaido Univ | インスリンを封入したイオントフォレーシス用リポソーム製剤 |
US9023094B2 (en) | 2007-06-25 | 2015-05-05 | Microvention, Inc. | Self-expanding prosthesis |
CA2724949A1 (en) | 2007-06-27 | 2008-12-31 | The General Hospital Corporation | Method and apparatus for optical inhibition of photodynamic therapy |
US8170660B2 (en) | 2007-12-05 | 2012-05-01 | The Invention Science Fund I, Llc | System for thermal modulation of neural activity |
US8180446B2 (en) | 2007-12-05 | 2012-05-15 | The Invention Science Fund I, Llc | Method and system for cyclical neural modulation based on activity state |
US8165669B2 (en) | 2007-12-05 | 2012-04-24 | The Invention Science Fund I, Llc | System for magnetic modulation of neural conduction |
US8165668B2 (en) | 2007-12-05 | 2012-04-24 | The Invention Science Fund I, Llc | Method for magnetic modulation of neural conduction |
US8170658B2 (en) | 2007-12-05 | 2012-05-01 | The Invention Science Fund I, Llc | System for electrical modulation of neural conduction |
US8180447B2 (en) | 2007-12-05 | 2012-05-15 | The Invention Science Fund I, Llc | Method for reversible chemical modulation of neural activity |
US8160695B2 (en) | 2007-12-05 | 2012-04-17 | The Invention Science Fund I, Llc | System for chemical modulation of neural activity |
US8195287B2 (en) | 2007-12-05 | 2012-06-05 | The Invention Science Fund I, Llc | Method for electrical modulation of neural conduction |
US11890371B2 (en) * | 2007-12-26 | 2024-02-06 | Petvivo Holdings, Inc. | Biocompatible protein-based particles and methods thereof |
US8862223B2 (en) | 2008-01-18 | 2014-10-14 | Activatek, Inc. | Active transdermal medicament patch and circuit board for same |
PL2285362T3 (pl) * | 2008-06-19 | 2017-12-29 | Lts Lohmann Therapie-Systeme Ag | Kompozycja do przezskórnego dostarczania kationowych substancji czynnych |
US20100022497A1 (en) * | 2008-07-24 | 2010-01-28 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Method for treating or preventing a cardiovascular disease or condition utilizing estrogen receptor modulators based on APOE allelic profile of a mammalian subject |
US20100061976A1 (en) * | 2008-07-24 | 2010-03-11 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Method for treating or preventing osteoporosis by reducing follicle stimulating hormone to cyclic physiological levels in a mammalian subject |
US20100022991A1 (en) * | 2008-07-24 | 2010-01-28 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | System and device for maintaining physiological levels of steroid hormone in a subject |
US20100022494A1 (en) * | 2008-07-24 | 2010-01-28 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Method, device, and kit for maintaining physiological levels of steroid hormone in a subject |
WO2010057177A2 (en) | 2008-11-17 | 2010-05-20 | Gel-Del Technologies, Inc. | Protein biomaterial and biocoacervate vessel graft systems and methods of making and using thereof |
TW201043287A (en) * | 2009-05-08 | 2010-12-16 | Isis Biopolymer Llc | Iontophoretic device with improved counterelectrode |
US20110092881A1 (en) * | 2009-05-08 | 2011-04-21 | Isis Biopolymer Inc. | Iontophoretic device with contact sensor |
EP2498764B1 (de) | 2009-11-09 | 2017-09-06 | Spotlight Technology Partners LLC | Fragmentierte hydrogele |
CA2780294C (en) | 2009-11-09 | 2018-01-16 | Spotlight Technology Partners Llc | Polysaccharide based hydrogels |
JP2014522263A (ja) | 2011-05-11 | 2014-09-04 | マイクロベンション インコーポレイテッド | 内腔を閉塞するためのデバイス |
EP2886153A1 (de) | 2013-12-20 | 2015-06-24 | LTS LOHMANN Therapie-Systeme AG | System für die transdermale Abgabe von Wirkstoff |
EP3181117A1 (de) * | 2015-12-15 | 2017-06-21 | L'oreal | Vitamin-c-zusammensetzung und ein verfahren zu deren verabreichung durch iontophorese |
Family Cites Families (55)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3998215A (en) * | 1968-12-18 | 1976-12-21 | Minnesota Mining And Manufacturing Company | Bio-medical electrode conductive gel pads |
CS159361B1 (de) * | 1970-09-08 | 1975-01-31 | ||
CS164542B1 (de) * | 1973-02-15 | 1975-11-07 | ||
US3991755A (en) * | 1973-07-27 | 1976-11-16 | Medicon, Inc. | Iontophoresis apparatus for applying local anesthetics |
US3929741A (en) * | 1974-07-16 | 1975-12-30 | Datascope Corp | Hydrophilic acrylamido polymers |
US4094822A (en) * | 1974-12-26 | 1978-06-13 | Kater John A R | Bio-event electrode material |
US3994302A (en) * | 1975-08-14 | 1976-11-30 | Medtronic, Inc. | Stimulation electrode of ion-exchange material |
US4051842A (en) * | 1975-09-15 | 1977-10-04 | International Medical Corporation | Electrode and interfacing pad for electrical physiological systems |
US4274420A (en) * | 1975-11-25 | 1981-06-23 | Lectec Corporation | Monitoring and stimulation electrode |
US4066078A (en) * | 1976-02-05 | 1978-01-03 | Johnson & Johnson | Disposable electrode |
DE2626348C3 (de) * | 1976-06-11 | 1980-01-31 | Siemens Ag, 1000 Berlin Und 8000 Muenchen | Implantierbare Dosiereinrichtung |
US4141359A (en) * | 1976-08-16 | 1979-02-27 | University Of Utah | Epidermal iontophoresis device |
US4273135A (en) * | 1977-08-19 | 1981-06-16 | Minnesota Mining And Manufacturing Company | Biomedical electrode |
US4352359A (en) * | 1977-08-19 | 1982-10-05 | Minnesota Mining And Manufacturing Company | Biomedical electrode |
CA1153427A (en) * | 1978-12-11 | 1983-09-06 | Patrick T. Cahalan | Tape electrode |
GB2046764B (en) * | 1979-02-08 | 1983-04-20 | Matburn Holdings Ltd | Polymeric sealant compositions |
US4524087A (en) * | 1980-01-23 | 1985-06-18 | Minnesota Mining And Manufacturing Company | Conductive adhesive and biomedical electrode |
US4383529A (en) * | 1980-11-03 | 1983-05-17 | Wescor, Inc. | Iontophoretic electrode device, method and gel insert |
US4820263A (en) * | 1981-03-06 | 1989-04-11 | Medtronic, Inc. | Apparatus and method for iontophoretic drug delivery |
US4768523A (en) * | 1981-04-29 | 1988-09-06 | Lifecore Biomedical, Inc. | Hydrogel adhesive |
JPS5810066A (ja) * | 1981-07-10 | 1983-01-20 | 株式会社アドバンス | イオントフオレ−ゼ用プラスタ−構造体 |
US4419092A (en) * | 1981-11-06 | 1983-12-06 | Motion Control, Inc. | Iontophoretic electrode structure |
US4693711A (en) * | 1981-12-22 | 1987-09-15 | Bremer Roger E | Long-life biomedical transcutaneous drug application device and method of transcutaneous application of drugs |
US4526176A (en) * | 1981-12-22 | 1985-07-02 | Frantz Medical Development Ltd. | Long-life biomedical application device, particularly electrode, and method of transferring electrical current |
US4699146A (en) * | 1982-02-25 | 1987-10-13 | Valleylab, Inc. | Hydrophilic, elastomeric, pressure-sensitive adhesive |
US4622031A (en) * | 1983-08-18 | 1986-11-11 | Drug Delivery Systems Inc. | Indicator for electrophoretic transcutaneous drug delivery device |
US4557723A (en) * | 1983-08-18 | 1985-12-10 | Drug Delivery Systems Inc. | Applicator for the non-invasive transcutaneous delivery of medicament |
US4708716A (en) * | 1983-08-18 | 1987-11-24 | Drug Delivery Systems Inc. | Transdermal drug applicator |
US4747845A (en) * | 1983-10-17 | 1988-05-31 | Enquay Pharmaceutical Associates | Synthetic resin matrix system for the extended delivery of drugs |
US4601286A (en) * | 1984-04-20 | 1986-07-22 | Kaufman Jack W | Article for the protection of living tissues |
CA1267937A (en) * | 1984-10-29 | 1990-04-17 | Joseph Bradley Phipps | Iontophoretic drug delivery |
US4747819A (en) * | 1984-10-29 | 1988-05-31 | Medtronic, Inc. | Iontophoretic drug delivery |
US4655767A (en) * | 1984-10-29 | 1987-04-07 | Dow Corning Corporation | Transdermal drug delivery devices with amine-resistant silicone adhesives |
US4744787A (en) * | 1984-10-29 | 1988-05-17 | Medtronic, Inc. | Iontophoresis apparatus and methods of producing same |
US4585652A (en) * | 1984-11-19 | 1986-04-29 | Regents Of The University Of Minnesota | Electrochemical controlled release drug delivery system |
US4593053A (en) * | 1984-12-07 | 1986-06-03 | Medtronic, Inc. | Hydrophilic pressure sensitive biomedical adhesive composition |
GB8509978D0 (en) * | 1985-04-18 | 1985-05-30 | Juhasz L | Wound dressings |
US4645502A (en) * | 1985-05-03 | 1987-02-24 | Alza Corporation | Transdermal delivery of highly ionized fat insoluble drugs |
DE3533114A1 (de) * | 1985-09-17 | 1987-03-26 | Berolina Kunststoff | Teilbarer flaschenkasten |
US4722726A (en) * | 1986-02-12 | 1988-02-02 | Key Pharmaceuticals, Inc. | Method and apparatus for iontophoretic drug delivery |
US4915685A (en) * | 1986-03-19 | 1990-04-10 | Petelenz Tomasz J | Methods and apparatus for iontophoresis application of medicaments at a controlled ph through ion exchange |
IE60941B1 (en) * | 1986-07-10 | 1994-09-07 | Elan Transdermal Ltd | Transdermal drug delivery device |
US4734090A (en) * | 1986-07-18 | 1988-03-29 | Drug Delivery Systems Inc. | Electrical transdermal drug applicator |
JPS63102768A (ja) * | 1986-10-20 | 1988-05-07 | 山之内製薬株式会社 | イオントフオレ−シス用の新規プラスタ−構造体 |
US4786277A (en) * | 1986-11-21 | 1988-11-22 | Trustees Of Boston University | Electrodes, electrode assemblies, methods, and systems for tissue stimulation |
GB2204497B (en) * | 1986-11-21 | 1991-02-27 | Univ Boston | Electrode assembly for transdermal drug delivery |
US4731049A (en) * | 1987-01-30 | 1988-03-15 | Ionics, Incorporated | Cell for electrically controlled transdermal drug delivery |
EP0318776A1 (de) * | 1987-12-04 | 1989-06-07 | Robert Tapper | Verfahren und Gerät zur Verminderung des Hautverletzung bei Gebrauch von Elektroden |
US4814168A (en) * | 1988-03-04 | 1989-03-21 | Noven Pharmaceuticals, Inc. | Transdermal multipolymer drug delivery system |
IL86076A (en) * | 1988-04-14 | 1992-12-01 | Inventor S Funding Corp Ltd | Transdermal drug delivery device |
US4927408A (en) * | 1988-10-03 | 1990-05-22 | Alza Corporation | Electrotransport transdermal system |
US5057072A (en) * | 1988-10-28 | 1991-10-15 | Medtronic, Inc. | Iontophoresis electrode |
US5084008A (en) * | 1989-12-22 | 1992-01-28 | Medtronic, Inc. | Iontophoresis electrode |
US5084006A (en) * | 1990-03-30 | 1992-01-28 | Alza Corporation | Iontopheretic delivery device |
EP0521988B1 (de) * | 1990-03-30 | 1995-12-13 | Alza Corporation | Gerät zur iontophoretischen verabreichung von medikamenten |
-
1991
- 1991-03-26 EP EP91907000A patent/EP0521988B1/de not_active Expired - Lifetime
- 1991-03-26 ES ES91907000T patent/ES2082973T3/es not_active Expired - Lifetime
- 1991-03-26 CA CA002079315A patent/CA2079315C/en not_active Expired - Lifetime
- 1991-03-26 DE DE69115471T patent/DE69115471T2/de not_active Expired - Lifetime
- 1991-03-26 AU AU75652/91A patent/AU657681B2/en not_active Ceased
- 1991-03-26 AT AT91907000T patent/ATE131392T1/de not_active IP Right Cessation
- 1991-03-26 DK DK91907000.3T patent/DK0521988T3/da active
- 1991-03-28 IE IE108291A patent/IE74127B1/en not_active IP Right Cessation
- 1991-04-01 PT PT97217A patent/PT97217B/pt not_active IP Right Cessation
-
1992
- 1992-09-28 NO NO92923770A patent/NO923770L/no unknown
- 1992-09-29 FI FI924382A patent/FI924382A/fi not_active Application Discontinuation
-
1993
- 1993-07-30 US US08/100,071 patent/US5423739A/en not_active Expired - Lifetime
-
1994
- 1994-12-01 US US08/347,694 patent/US5558633A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
FI924382A0 (fi) | 1992-09-29 |
PT97217A (pt) | 1992-01-31 |
IE911082A1 (en) | 1991-10-09 |
AU657681B2 (en) | 1995-03-23 |
FI924382A (fi) | 1992-09-29 |
CA2079315A1 (en) | 1991-10-01 |
ATE131392T1 (de) | 1995-12-15 |
AU7565291A (en) | 1991-10-30 |
US5558633A (en) | 1996-09-24 |
EP0521988B1 (de) | 1995-12-13 |
IE74127B1 (en) | 1997-07-02 |
NO923770L (no) | 1992-11-30 |
US5423739A (en) | 1995-06-13 |
NO923770D0 (no) | 1992-09-28 |
ES2082973T3 (es) | 1996-04-01 |
DE69115471D1 (de) | 1996-01-25 |
EP0521988A1 (de) | 1993-01-13 |
PT97217B (pt) | 1998-11-30 |
CA2079315C (en) | 2003-04-15 |
DK0521988T3 (da) | 1996-04-29 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DE69115471T2 (de) | Gerät zur iontophoretischen verabreichung von medikamenten | |
MY100066A (en) | Multicompartmentalized dermal and transdermal patches. | |
BR8404119A (pt) | Aplicador para migracao eletroforetica de um medicamento em solucao ou suspensao ionica,atraves da pele,dentro de uma corrente do sangue de um paciente | |
ATE124270T1 (de) | Pharmazeutisch aktive bestandteile enthaltende adhesivpflaster. | |
DE69330710D1 (de) | Elektrode und gebrauchsfertige Schicht vom Gel zum Verwenden mit einer Elektrode | |
ES2151025T3 (es) | Vendajes para heridas. | |
GR3018977T3 (en) | Galvanic, active, transdermal, therapeutic system. | |
DK662887A (da) | Fladeformigt terapeutisk system, fremgangsmaade til fremstilling deraf og anvendelse deraf | |
ATE155347T1 (de) | Gerät zur iontophoretischen verabreichung von medikamenten | |
ATE17191T1 (de) | Chirurgisches heftpflaster. | |
DE3485213D1 (de) | Chirurgisches heftpflaster. | |
CA2229185A1 (en) | Plaster structure for iontophoresis | |
DE3769707D1 (de) | Therapeutisches system mit geregelter wirkstoffabgabe. | |
KR890700375A (ko) | 피부에 유효약제를 조절하여 투여하는 유효약제-함유 플래스터 | |
MY111126A (en) | Transdermal therapeutic system comprising the active substance acetylsalicylic acid. | |
GB1490065A (en) | Dressings | |
NO982621L (no) | Overflate-stabilisert farmas°ytisk bearbeiding for anvendelse pÕ huden | |
JPS609223Y2 (ja) | 貼薬シ−ト | |
ZA787352B (en) | Pharmacologically active heterocyclic compounds and their use in medicine | |
ES1037774U (es) | Aposito antiseptico aplicable a puntos de insercion de cateteres. | |
NO991047L (no) | Transdermal terapeutisk tilnµrming involverende en kombinasjon av aktive substanser inneholdende °striol | |
JPS59143419U (ja) | 救急セツト | |
SE8901145D0 (sv) | Gelvehikel foer aktiva substanser/laekemedel instabila vid lagring i vattenhaltiga geler |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |