DE69124915D1 - Neue zusammensetzungen lyophilisierter und wiederhergestellter zellen - Google Patents

Neue zusammensetzungen lyophilisierter und wiederhergestellter zellen

Info

Publication number
DE69124915D1
DE69124915D1 DE69124915T DE69124915T DE69124915D1 DE 69124915 D1 DE69124915 D1 DE 69124915D1 DE 69124915 T DE69124915 T DE 69124915T DE 69124915 T DE69124915 T DE 69124915T DE 69124915 D1 DE69124915 D1 DE 69124915D1
Authority
DE
Germany
Prior art keywords
lyophilized
new compositions
recovered cells
cells
matter
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69124915T
Other languages
English (en)
Inventor
Raymond Goodrich
Victoria Wong
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Terumo BCT Inc
Original Assignee
Cobe Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cobe Laboratories Inc filed Critical Cobe Laboratories Inc
Application granted granted Critical
Publication of DE69124915D1 publication Critical patent/DE69124915D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02—Preservation of living parts
    • A01N1/0205—Chemical aspects
    • A01N1/021—Preservation or perfusion media, liquids, solids or gases used in the preservation of cells, tissue, organs or bodily fluids
    • A01N1/0215—Disinfecting agents, e.g. antimicrobials for preserving living parts
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02—Preservation of living parts
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02—Preservation of living parts
    • A01N1/0205—Chemical aspects
    • A01N1/021—Preservation or perfusion media, liquids, solids or gases used in the preservation of cells, tissue, organs or bodily fluids
    • A01N1/0221—Freeze-process protecting agents, i.e. substances protecting cells from effects of the physical process, e.g. cryoprotectants, osmolarity regulators like oncotic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/19—Platelets; Megacaryocytes
DE69124915T 1990-05-17 1991-05-17 Neue zusammensetzungen lyophilisierter und wiederhergestellter zellen Expired - Lifetime DE69124915D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/525,392 US5213814A (en) 1989-04-10 1990-05-17 Lyophilized and reconstituted blood platelet compositions
PCT/US1991/003320 WO1991017655A1 (en) 1990-05-17 1991-05-17 Novel lyophilized and reconstituted cell compositions

Publications (1)

Publication Number Publication Date
DE69124915D1 true DE69124915D1 (de) 1997-04-10

Family

ID=24093064

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69124915T Expired - Lifetime DE69124915D1 (de) 1990-05-17 1991-05-17 Neue zusammensetzungen lyophilisierter und wiederhergestellter zellen

Country Status (10)

Country Link
US (1) US5213814A (de)
EP (1) EP0483329B1 (de)
JP (1) JPH05500231A (de)
AT (1) ATE149284T1 (de)
AU (1) AU7888391A (de)
CA (1) CA2064228C (de)
DE (1) DE69124915D1 (de)
IL (1) IL98182A0 (de)
WO (1) WO1991017655A1 (de)
ZA (1) ZA913774B (de)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL90188A0 (en) * 1988-05-18 1989-12-15 Cryopharm Corp Process and medium for the lyophilization of erythrocytes
US5045446A (en) * 1988-08-26 1991-09-03 Cryopharm Corporation Lyophilization of cells
US5428008A (en) * 1989-04-14 1995-06-27 Prp, Inc. Therapeutic composition of micellar structures capable of promoting hemotasis
US6251644B1 (en) 1990-04-16 2001-06-26 Baxter International, Inc. Method for inactivating non-enveloped viral contaminants with a photosensitizer by increasing viral permeability to the photosensitizer
US6187572B1 (en) * 1990-04-16 2001-02-13 Baxter International Inc. Method of inactivation of viral and bacterial blood contaminants
CA2062941A1 (en) * 1990-05-25 1991-11-26 Raymond P. Goodrich, Jr. Process for lyophilizing cells, cell-like materials and platelets in a mixture of biocompatable amphipathic polymers
US5376524A (en) * 1991-04-01 1994-12-27 Thomas Jefferson University Platelet storage medium containing acetate and phosphate
US5569579A (en) * 1991-04-01 1996-10-29 Thomas Jefferson University Synthetic-based platelet storage media
DK0642301T3 (da) * 1992-05-29 2003-06-23 Univ North Carolina Farmaceutisk acceptable fikserede, tørrede humane blodplader
US5690963A (en) * 1995-06-30 1997-11-25 The United States Of America As Represented By The Secretary Of The Navy Freeze dried red blood cells
US5736313A (en) * 1995-10-20 1998-04-07 The United States Of America As Represented By The Secretary Of The Navy Method of lyophilizing platelets by incubation with high carbohydrate concentrations and supercooling prior to freezing
EP0921814A4 (de) 1996-03-29 2001-10-04 Life Technologies Inc Verfahren zur Erhöhung der Lebensfähigkeit und der Transformationseffizienz von Bakterien während der Lagerung bei tiefen Temperaturen
DE19634313A1 (de) * 1996-08-24 1998-02-26 Behringwerke Ag Methode zur Stabilisierung von Plättchen
DE69829976T2 (de) 1997-02-12 2006-04-27 Invitrogen Corp., Carlsbad Verfahren zur herstellung von zellen
AT407484B (de) 1997-11-12 2001-03-26 Bio Prod & Bio Eng Ag Arzneimittel zur förderung der wundheilung
US6139878A (en) * 1998-04-27 2000-10-31 Aventis Behring, Llc Method for preparing a diafiltered stabilized blood product
US6413713B1 (en) 1998-10-30 2002-07-02 Hyperbaric Systems Method for preserving blood platelets
EP1232753B1 (de) * 1999-09-08 2008-03-19 Chugai Seiyaku Kabushiki Kaisha Stabile proteinlösung abgefüllt in einem behältnis aus hydrophobem harz und eine methode zur stabilisierung derselben
EP1244353B1 (de) * 1999-12-21 2004-11-17 Viacell, LLC Zusammensetzungen zur lagerung von blutplättchen
US6770478B2 (en) 2000-02-10 2004-08-03 The Regents Of The University Of California Erythrocytic cells and method for preserving cells
WO2001058266A1 (en) 2000-02-10 2001-08-16 The Regents Of The University Of California Therapeutic platelets and methods
EP1399018A1 (de) * 2001-06-26 2004-03-24 Human Biosystems Konservierung von blutplättchen bei kalten temperaturen
GB0230152D0 (en) * 2002-12-24 2003-02-05 Sinvent As Product
CA2522941A1 (en) 2003-04-23 2004-11-04 Human Biosystems Improved methods and solutions for storing donor organs
US20040229205A1 (en) * 2003-05-16 2004-11-18 Ericson Daniel G. Compositions for the storage of platelets
EP1659862A2 (de) 2003-08-04 2006-05-31 Human Biosystems Konservierung von blutzellen
ATE455463T1 (de) 2004-08-12 2010-02-15 Cellphire Inc Verfahren zur herstellung gefriergetrockneter blutplättchen, gefriergetrocknete blutplättchen enthaltende zusammensetzungen und verwendungsverfahren
EP1950283B1 (de) * 2005-11-17 2015-07-29 Nippon Zenyaku Kogyo Co., Ltd. Wässrige lösung zur zellkonservierung
US20090117057A1 (en) * 2007-11-06 2009-05-07 Shanbrom Technologies, Llc Grape Polyphenolics for Platelet and Bacterial Control
JP6254187B2 (ja) * 2012-12-20 2017-12-27 オムリックス・バイオファーマシューティカルズ・リミテッドＯｍｒｉｘ Ｂｉｏｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｌｔｄ． ウイルス不活性化生物学的混合物
EP3151662B1 (de) 2014-06-09 2020-10-21 Terumo BCT, Inc. Lyophilisierung
US10793327B2 (en) 2017-10-09 2020-10-06 Terumo Bct Biotechnologies, Llc Lyophilization container and method of using same
WO2020112963A1 (en) 2018-11-30 2020-06-04 Cellphire, Inc. Platelets as delivery agents
CN114127501B (zh) 2019-03-14 2023-02-17 泰尔茂比司特生物技术有限公司 多部分冻干容器及使用方法
US11529587B2 (en) 2019-05-03 2022-12-20 Cellphire, Inc. Materials and methods for producing blood products
AU2020334903B2 (en) 2019-08-16 2023-12-21 Cellphire, Inc. Thrombosomes as an antiplatelet agent reversal agent
CA3170198A1 (en) 2020-02-04 2021-08-12 Cellphire, Inc Methods of treating acquired hemophilia with anti-fibrinolytic loaded platelets
CN114617903A (zh) * 2022-03-15 2022-06-14 中国人民解放军总医院第一医学中心 一种用于血浆冻干的组合物及其应用

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2786014A (en) * 1952-09-10 1957-03-19 James L Tullis Platelet preservation
US3303662A (en) * 1963-03-01 1967-02-14 Union Carbide Corp Process for cell preservation
BE643051A (de) * 1963-05-31 1964-05-15
DE2546166A1 (de) * 1975-10-15 1977-04-28 Behringwerke Ag Gegerbte thrombozyten
US4059967A (en) * 1976-02-19 1977-11-29 The Community Blood Council Of Greater New York, Inc. Process for freezing blood platelets
US4961928A (en) * 1986-03-19 1990-10-09 American Red Cross Synthetic, plasma-free, transfusible storage medium for red blood cells and platelets
US4764463A (en) * 1986-10-30 1988-08-16 The University Of Tennessee Research Corporation Platelet cyropreservation
US5178884A (en) * 1988-05-18 1993-01-12 Cryopharm Corporation Lyophilized and reconstituted red blood cell compositions
US5153004A (en) * 1989-06-02 1992-10-06 Cryopharm Corporation Freezing and thawing of erythrocytes
US4874690A (en) * 1988-08-26 1989-10-17 Cryopharm Corporation Lyophilization of red blood cells
EP0356258A3 (de) * 1988-08-26 1990-06-06 Cryopharm Corporation Gefriertrocknungsmethode für rote Blutkörperchen und Mittel dafür
US4973327A (en) * 1989-11-01 1990-11-27 Cryopharm Blood bag for lyophilization
EP0483304B1 (de) * 1990-04-16 2003-02-19 Baxter International Inc. Methode zur unschädlichmachung viraler und bakterieller blutverunreinigungen
CA2062941A1 (en) * 1990-05-25 1991-11-26 Raymond P. Goodrich, Jr. Process for lyophilizing cells, cell-like materials and platelets in a mixture of biocompatable amphipathic polymers
CA2078004A1 (en) * 1991-02-15 1992-08-16 Christine M. Williams Method of lyophilization and reconstitution of mixtures of nucleated non-mammalian cells and blood matter

Also Published As

Publication number Publication date
AU7888391A (en) 1991-12-10
CA2064228A1 (en) 1991-11-18
ATE149284T1 (de) 1997-03-15
EP0483329B1 (de) 1997-03-05
ZA913774B (en) 1992-02-26
US5213814A (en) 1993-05-25
JPH05500231A (ja) 1993-01-21
WO1991017655A1 (en) 1991-11-28
EP0483329A1 (de) 1992-05-06
IL98182A0 (en) 1992-06-21
CA2064228C (en) 1999-04-06
EP0483329A4 (en) 1993-08-11

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