DE69126727T2 - Warm-behandelte IGM-Antikörper-Zusammensetzungen - Google Patents

Warm-behandelte IGM-Antikörper-Zusammensetzungen

Info

Publication number
DE69126727T2
DE69126727T2 DE69126727T DE69126727T DE69126727T2 DE 69126727 T2 DE69126727 T2 DE 69126727T2 DE 69126727 T DE69126727 T DE 69126727T DE 69126727 T DE69126727 T DE 69126727T DE 69126727 T2 DE69126727 T2 DE 69126727T2
Authority
DE
Germany
Prior art keywords
igm
heat treated
igm antibody
antibody compositions
concentrates
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69126727T
Other languages
English (en)
Other versions
DE69126727D1 (de
Inventor
Grace C Tsay
Gary Jesmok
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Bayer Corp
Original Assignee
Bayer AG
Bayer Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG, Bayer Corp filed Critical Bayer AG
Application granted granted Critical
Publication of DE69126727D1 publication Critical patent/DE69126727D1/de
Publication of DE69126727T2 publication Critical patent/DE69126727T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S424/00—Drug, bio-affecting and body treating compositions
    • Y10S424/806—Drug, bio-affecting and body treating compositions involving IgM
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/863—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof involving IgM
DE69126727T 1990-04-03 1991-03-21 Warm-behandelte IGM-Antikörper-Zusammensetzungen Expired - Lifetime DE69126727T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/504,161 US5256771A (en) 1990-04-03 1990-04-03 Heat treatment of IgM-containing immunoglobulins to eliminate non-specific complement activation

Publications (2)

Publication Number Publication Date
DE69126727D1 DE69126727D1 (de) 1997-08-14
DE69126727T2 true DE69126727T2 (de) 1997-10-23

Family

ID=24005109

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69126727T Expired - Lifetime DE69126727T2 (de) 1990-04-03 1991-03-21 Warm-behandelte IGM-Antikörper-Zusammensetzungen

Country Status (9)

Country Link
US (3) US5256771A (de)
EP (1) EP0450412B1 (de)
JP (1) JP3591782B2 (de)
AT (1) ATE155042T1 (de)
CA (1) CA2039387C (de)
DE (1) DE69126727T2 (de)
DK (1) DK0450412T3 (de)
ES (1) ES2104625T3 (de)
GR (1) GR3024910T3 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6297024B1 (en) 1998-10-15 2001-10-02 Cell Activation, Inc. Methods for assessing complement activation
US6235494B1 (en) 1999-02-08 2001-05-22 The Scripps Research Institute Substrates for assessing mannan-binding protein-associated serine protease activity and methods using the substrates
PL1648427T3 (pl) 2003-05-16 2014-05-30 Mayo Found Medical Education & Res Leczenie zaburzeń demielinizacyjnych niskimi dawkami przeciwciała IgM
GB0425537D0 (en) * 2004-11-19 2004-12-22 Celltech R&D Ltd Process for obtaining antibodies
GB201006753D0 (en) * 2010-04-22 2010-06-09 Biotest Ag Process for preparing an immunolobulin composition
FR2959821B1 (fr) * 2010-05-05 2012-07-06 Lab Francais Du Fractionnement Procede de mesure de l'activation du complement par des igg
EP3275897A1 (de) 2016-07-27 2018-01-31 Biotest AG Verfahren zur herstellung von immunoglobulinzusammensetzungen
CN110536900A (zh) 2017-04-07 2019-12-03 Igm生物科学股份有限公司 调节补体依赖性细胞溶解效应子功能的修饰的人igm恒定区
AU2021303496A1 (en) * 2020-07-10 2023-02-02 Grifols Worldwide Operations Limited Method for obtaining a composition comprising human plasma-derived immunoglobulin M

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2527064C3 (de) * 1975-06-18 1979-11-15 Biotest-Serum-Institut Gmbh, 6000 Frankfurt Verfahren zur Herstellung eines intravenösen Nativ-Human-Immunglobulin-Präparates mit natürlicher Halbwertszeit und gegenüber dem Ausgangsmaterial unveränderten Antikörperaktivität
DE2835843A1 (de) * 1978-08-16 1980-02-28 Blutspendedienst Dt Rote Kreuz Verfahren zur herstellung einer fuer die intravenoese anwendung geeigneten gammaglobulinloesung
DE2901822A1 (de) * 1979-01-18 1980-07-31 Biotest Serum Institut Gmbh Verfahren zur herstellung einer fuer die intravenoese applikation geeigneten immunglobulinloesung, die igm in ankonzentrierter form enthaelt
JPS56147724A (en) * 1980-04-18 1981-11-16 Teijin Ltd Igm derivative and immunoglobulin preparation for intravenous injection containing said compound as effective component
JPS57140724A (en) * 1981-02-25 1982-08-31 Green Cross Corp:The Heat-treatment of aqueous solution containing cold insoluble globulin
ATE19735T1 (de) * 1982-02-08 1986-05-15 Schweiz Serum & Impfinst Intravenoes verabreichbares humanes immunglobulin und verfahren zu dessen herstellung.
JPH0669961B2 (ja) * 1984-09-25 1994-09-07 株式会社ミドリ十字 免疫グロブリンの加熱処理方法
DE3825429C2 (de) * 1988-07-27 1994-02-10 Biotest Pharma Gmbh Verfahren zur Herstellung eines intravenös verabreichbaren polyklonalen Immunglobulin-Präparates mit hohem IgM-Gehalt
DE3927111C3 (de) * 1989-08-17 1994-09-01 Biotest Pharma Gmbh Verfahren zur Herstellung nicht modifizierter intravenös verabreichbarer IgM- und/oderIgA-haltiger Immunglobulinpräparate

Also Published As

Publication number Publication date
US5510465A (en) 1996-04-23
ATE155042T1 (de) 1997-07-15
EP0450412B1 (de) 1997-07-09
JPH04221321A (ja) 1992-08-11
ES2104625T3 (es) 1997-10-16
US5612033A (en) 1997-03-18
DK0450412T3 (da) 1998-02-16
US5256771A (en) 1993-10-26
EP0450412A1 (de) 1991-10-09
CA2039387C (en) 2002-02-19
JP3591782B2 (ja) 2004-11-24
DE69126727D1 (de) 1997-08-14
CA2039387A1 (en) 1991-10-04
GR3024910T3 (en) 1998-01-30

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ISHIZAKA y-GLOBULIN

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