DE69202872D1 - Vorrichtung und Verfahren zur Erneuerung von Elektroden während der Iontophorese. - Google Patents

Vorrichtung und Verfahren zur Erneuerung von Elektroden während der Iontophorese.

Info

Publication number
DE69202872D1
DE69202872D1 DE69202872T DE69202872T DE69202872D1 DE 69202872 D1 DE69202872 D1 DE 69202872D1 DE 69202872 T DE69202872 T DE 69202872T DE 69202872 T DE69202872 T DE 69202872T DE 69202872 D1 DE69202872 D1 DE 69202872D1
Authority
DE
Germany
Prior art keywords
electrodes
active agent
reservoir
housing
electrode
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69202872T
Other languages
English (en)
Other versions
DE69202872T2 (de
Inventor
Burton H Sage
Carl R Bock
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Vyteris Inc
Original Assignee
Becton Dickinson and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Becton Dickinson and Co filed Critical Becton Dickinson and Co
Application granted granted Critical
Publication of DE69202872D1 publication Critical patent/DE69202872D1/de
Publication of DE69202872T2 publication Critical patent/DE69202872T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/20—Applying electric currents by contact electrodes continuous direct currents
    • A61N1/30—Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A61N1/0432—Anode and cathode
    • A61N1/044—Shape of the electrode
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A61N1/0448—Drug reservoir
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/20—Applying electric currents by contact electrodes continuous direct currents
    • A61N1/30—Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis
    • A61N1/303—Constructional details
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A61N1/0432—Anode and cathode
    • A61N1/0436—Material of the electrode
DE69202872T 1991-02-08 1992-02-04 Vorrichtung und Verfahren zur Erneuerung von Elektroden während der Iontophorese. Expired - Fee Related DE69202872T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/652,855 US5320597A (en) 1991-02-08 1991-02-08 Device and method for renewing electrodes during iontophoresis

Publications (2)

Publication Number Publication Date
DE69202872D1 true DE69202872D1 (de) 1995-07-20
DE69202872T2 DE69202872T2 (de) 1995-11-02

Family

ID=24618454

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69202872T Expired - Fee Related DE69202872T2 (de) 1991-02-08 1992-02-04 Vorrichtung und Verfahren zur Erneuerung von Elektroden während der Iontophorese.

Country Status (16)

Country Link
US (1) US5320597A (de)
EP (1) EP0498353B1 (de)
JP (1) JPH067868B2 (de)
KR (1) KR940006528B1 (de)
AT (1) ATE123660T1 (de)
AU (1) AU644917B2 (de)
BR (1) BR9105499A (de)
CA (1) CA2056015C (de)
DE (1) DE69202872T2 (de)
DK (1) DK0498353T3 (de)
ES (1) ES2073196T3 (de)
FI (1) FI920534A (de)
GR (1) GR3017405T3 (de)
IE (1) IE67142B1 (de)
MX (1) MX9200176A (de)
NO (1) NO914893L (de)

Families Citing this family (75)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6238381B1 (en) * 1990-11-01 2001-05-29 Robert Tapper Iontophoretic treatment system
IL105073A0 (en) † 1992-03-17 1993-07-08 Becton Dickinson Co User activated iontophoretic device and method for using same
JP2542792B2 (ja) * 1992-11-05 1996-10-09 ベクトン・ディッキンソン・アンド・カンパニー ユ―ザ作動型のイオン導入式装置
US5445609A (en) * 1993-05-28 1995-08-29 Alza Corporation Electrotransport agent delivery device having a disposable component and a removable liner
CA2126487C (en) * 1993-06-23 2001-05-29 Keiichiro Okabe Iontophoresis device
FR2709670B1 (fr) * 1993-09-10 1995-10-20 Asulab Sa Dispositif en trois modules pour l'administration transdermique de médicaments par électrophorèse ou iontophorèse.
US5387189A (en) * 1993-12-02 1995-02-07 Alza Corporation Electrotransport delivery device and method of making same
JP2716361B2 (ja) * 1994-02-16 1998-02-18 株式会社アドバンス 生体用プリント電極
JP3119486B2 (ja) * 1994-06-17 2000-12-18 久光製薬株式会社 イオントフォレーシス用電極及びそれを用いたデバイス
US5562607A (en) * 1995-01-18 1996-10-08 Alza Corporation Electrotransport device having reusable controller power saver
FR2729575B1 (fr) * 1995-01-24 1997-07-04 Elf Aquitaine Dispositif d'ionophorese pour l'administration transcutanee d'un principe actif de type glycosaminoglycane anionique de basse masse moleculaire
AU4626196A (en) * 1995-01-24 1996-08-14 Akzo Nobel N.V. Iontophoresis device for the transcutaneous delivery of an active principle such as an anionic oligosaccharide
US5990179A (en) * 1995-04-28 1999-11-23 Alza Corporation Composition and method of enhancing electrotransport agent delivery
GB2317343B (en) * 1995-05-15 1999-06-23 Alza Corp Electrotransport device having reusable controller
US6425892B2 (en) * 1995-06-05 2002-07-30 Alza Corporation Device for transdermal electrotransport delivery of fentanyl and sufentanil
US6881208B1 (en) 1995-06-05 2005-04-19 Joseph B. Phipps Method and device for transdermal electrotransport delivery of fentanyl and sufentanil
PT836511E (pt) 1995-06-05 2004-08-31 Alza Corp Dispositivo para distribuicao de fentanilo e sufentanilo por electrotransporte percutaneo
IE960375A1 (en) * 1995-06-05 1996-12-11 Alza Corp Device for transdermal electrotransport delivery of fentanyl¹and sufentanil
US6216033B1 (en) 1996-05-22 2001-04-10 Alza Corporation Device for transdermal electrotransport delivery of fentanyl and sufentanil
US6355025B1 (en) 1995-06-07 2002-03-12 Alza Corporation Adjustable electrotransport drug delivery using a fixed output controller
US5861431A (en) * 1995-06-07 1999-01-19 Iotek, Inc. Incontinence treatment
US6316022B1 (en) 1995-06-07 2001-11-13 Noven Pharmaceuticals, Inc. Transdermal compositions containing low molecular weight drugs which are liquid at room temperatures
EP0833671A2 (de) * 1995-06-07 1998-04-08 Noven Pharmaceuticals, Inc. Transdermale mittel, die bei raumtemperatur flüssige niedermolekulare arzneistoffe enthalten
WO1997018855A1 (en) * 1995-11-21 1997-05-29 Eduard Naumovich Lerner Device for enhanced delivery of biologically active substances and compounds in an organism
AU1687997A (en) * 1995-12-28 1997-07-28 Becton Dickinson & Company Molecules for iontophoretic delivery
WO1997048444A1 (en) * 1996-06-19 1997-12-24 Becton Dickinson And Company Iontophoretic delivery of cell adhesion inhibitors
US5792097A (en) * 1996-09-27 1998-08-11 Becton Dickinson And Company Iontophoretic electrodes and surface active agents
US6018679A (en) * 1997-01-29 2000-01-25 Novartis Finance Corp. Iontophoretic transdermal delivery and control of adverse side-effects
JP3366548B2 (ja) * 1997-02-26 2003-01-14 久光製薬株式会社 イオントフォレーシス用デバイス構造体及びその製造方法
US5991655A (en) * 1997-03-03 1999-11-23 Drug Delivery Systems, Inc. Iontophoretic drug delivery device and method of manufacturing the same
US5846217A (en) * 1997-07-29 1998-12-08 Iomed, Inc. Iontophoretic bioelectrode and method of using same
WO1999018797A1 (en) 1997-10-09 1999-04-22 Emory University Method and devices for transdermal delivery of lithium
US6295469B1 (en) 1997-11-14 2001-09-25 Alza Corporation Formulation for electrically assisted delivery of lidocaine and epinephrine
CN1147330C (zh) 1998-01-28 2004-04-28 阿尔扎有限公司 用于电传输装置的电化学反应性阴极
JPH11239621A (ja) * 1998-02-25 1999-09-07 Hisamitsu Pharmaceut Co Inc イオントフォレーシス装置
US6858018B1 (en) * 1998-09-28 2005-02-22 Vyteris, Inc. Iontophoretic devices
US20070196490A1 (en) * 1999-01-22 2007-08-23 Powderject Research Limited Method of enhancing needleless transdermal powered drug delivery
US6792306B2 (en) * 2000-03-10 2004-09-14 Biophoretic Therapeutic Systems, Llc Finger-mounted electrokinetic delivery system for self-administration of medicaments and methods therefor
JP4410421B2 (ja) 1999-04-13 2010-02-03 久光製薬株式会社 イオントフォレーシスデバイス
US7083580B2 (en) * 2001-04-06 2006-08-01 Mattioli Engineering Ltd. Method and apparatus for skin absorption enhancement and transdermal drug delivery
US7520875B2 (en) * 2001-04-06 2009-04-21 Mattioli Engineering Ltd. Method and apparatus for skin absorption enhancement and transdermal drug delivery
FR2830766B1 (fr) * 2001-10-12 2004-03-12 Optis France Sa Dispositif de delivrance de medicaments par iontophorese transpalpebrale
DE10205373B4 (de) * 2002-02-09 2007-07-19 Aloys Wobben Brandschutz
AU2003280136A1 (en) * 2002-06-28 2004-01-19 Alza Corporation A reservoir for use in an electrotransport drug delivery device
IL152573A (en) * 2002-10-31 2009-11-18 Transpharma Medical Ltd A system for the transmission through the skin of a medical preparation against vomiting and nausea
IL152575A (en) * 2002-10-31 2008-12-29 Transpharma Medical Ltd A skin-to-skin transmission system of water-insoluble drugs
CA2587780A1 (en) * 2004-11-18 2006-05-26 Transpharma Medical Ltd. Combined micro-channel generation and iontophoresis for transdermal delivery of pharmaceutical agents
US20090143761A1 (en) * 2005-06-03 2009-06-04 Transdermal Patents Company, Llc Agent delivery system and uses of same
WO2006133103A2 (en) * 2005-06-03 2006-12-14 Trans-Dermal Patents Company, Llc Reservoir for delivery of agents
US8295922B2 (en) 2005-08-08 2012-10-23 Tti Ellebeau, Inc. Iontophoresis device
US20070088332A1 (en) * 2005-08-22 2007-04-19 Transcutaneous Technologies Inc. Iontophoresis device
JPWO2007032446A1 (ja) 2005-09-15 2009-03-19 Ｔｔｉ・エルビュー株式会社 ロッド型イオントフォレーシス装置
US20070078445A1 (en) * 2005-09-30 2007-04-05 Curt Malloy Synchronization apparatus and method for iontophoresis device to deliver active agents to biological interfaces
EP1965858A2 (de) * 2005-12-30 2008-09-10 Tti Ellebeau, Inc. System und verfahren zur fernsteuerung eines iontophoresegerätes
WO2007088897A1 (ja) * 2006-01-31 2007-08-09 Tti Ellebeau, Inc. カートリッジ型イオントフォレーシス装置
JP2007229003A (ja) * 2006-02-27 2007-09-13 Transcutaneous Technologies Inc イオントフォレーシス装置
US20080004671A1 (en) * 2006-06-28 2008-01-03 Alza Corporation Vagus nerve stimulation via orally delivered apparatus
US20080009782A1 (en) * 2006-06-28 2008-01-10 Alza Corporation Methods and Devices for Transdermal Electrotransport Delivery of Lofentanil and Carfentanil
JP4934405B2 (ja) * 2006-11-02 2012-05-16 株式会社Ｊｉｕ−Ｋｉｄｄ イオントフォレーシスによる投与方法及び装置
JP5383497B2 (ja) 2006-12-01 2014-01-08 Ｔｔｉ・エルビュー株式会社 装置、例として経皮送達装置に給電し且つ／又は当該装置を制御するシステム及び装置
US20080234627A1 (en) * 2007-03-22 2008-09-25 Wanda Dent Pivotally engaged multiple part electrotransport drug delivery device
US8197844B2 (en) 2007-06-08 2012-06-12 Activatek, Inc. Active electrode for transdermal medicament administration
EP2043733A1 (de) 2007-06-26 2009-04-08 Alza Corporation Verfahren und vorrichtungen zur transdermalen elektrotransport-verabreichung von lofentanil und carfentanil
CA2724949A1 (en) 2007-06-27 2008-12-31 The General Hospital Corporation Method and apparatus for optical inhibition of photodynamic therapy
US20090043244A1 (en) * 2007-08-08 2009-02-12 Inan Omer T Electrotransport Drug Delivery Device Adaptable to Skin Resistance Change
US8862223B2 (en) 2008-01-18 2014-10-14 Activatek, Inc. Active transdermal medicament patch and circuit board for same
US20090312689A1 (en) * 2008-06-05 2009-12-17 Alza Corporation Adjustable Current Electrotransport Fentanyl Delivery Device
US20110306878A1 (en) 2009-02-26 2011-12-15 Liquidia Technologies, Inc. Interventional drug delivery system and associated methods
JP5463136B2 (ja) * 2009-12-22 2014-04-09 帝國製薬株式会社 イオントフォレーシス療法に用いる電極装置
US8428709B1 (en) 2012-06-11 2013-04-23 Incline Therapeutics, Inc. Current control for electrotransport drug delivery
US8301238B2 (en) 2011-03-31 2012-10-30 Incline Therapeutics, Inc. Two-part electrotransport device
US8428708B1 (en) 2012-05-21 2013-04-23 Incline Therapeutics, Inc. Self-test for analgesic product
US9731121B2 (en) 2011-03-31 2017-08-15 Incline Therapeutics, Inc. Switch validation circuit and method
US8781571B2 (en) 2011-03-31 2014-07-15 Incline Therapeutics, Inc. Switch validation circuit and method
US9744353B2 (en) * 2012-11-14 2017-08-29 Teva Pharmaceuticals International Gmbh Detection of presence and alignment of a therapeutic agent in an iontophoretic drug delivery device

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4019510A (en) * 1975-02-10 1977-04-26 Sybron Corporation Therapeutic method of using low intensity direct current generator with polarity reversal
US4325367A (en) * 1977-06-13 1982-04-20 Robert Tapper Iontophoretic treatment apparatus
US4177817A (en) * 1978-02-01 1979-12-11 C. R. Bard, Inc. Dual terminal transcutaneous electrode
US4383529A (en) * 1980-11-03 1983-05-17 Wescor, Inc. Iontophoretic electrode device, method and gel insert
US4406658A (en) * 1981-03-06 1983-09-27 Medtronic, Inc. Iontophoretic device with reversible polarity
US4747819A (en) * 1984-10-29 1988-05-31 Medtronic, Inc. Iontophoretic drug delivery
US4744787A (en) * 1984-10-29 1988-05-17 Medtronic, Inc. Iontophoresis apparatus and methods of producing same
JPS62139672A (ja) * 1985-12-14 1987-06-23 林原　健 正負イオントホレ−ゼ用治療器
US4752285B1 (en) * 1986-03-19 1995-08-22 Univ Utah Res Found Methods and apparatus for iontophoresis application of medicaments
US4886489A (en) * 1986-03-19 1989-12-12 Jacobsen Stephen C Flow-through methods and apparatus for iontophoresis application of medicaments at a controlled pH
US5042975A (en) * 1986-07-25 1991-08-27 Rutgers, The State University Of New Jersey Iontotherapeutic device and process and iontotherapeutic unit dose
DE3703321A1 (de) * 1986-09-01 1988-03-10 Transcutan Gmbh Therapievorrichtung zur anwendung von elektrischem strom
JPS63145669A (ja) * 1986-10-11 1988-06-17 林原　健 正、負イオントホレ−ゼ用スイッチ
US5013293A (en) * 1987-05-28 1991-05-07 Drug Delivery Systems Inc. Pulsating transdermal drug delivery system
US4942883A (en) * 1987-09-29 1990-07-24 Newman Martin H Drug delivery device
US5006108A (en) * 1988-11-16 1991-04-09 Noven Pharmaceuticals, Inc. Apparatus for iontophoretic drug delivery
US5047007A (en) * 1989-12-22 1991-09-10 Medtronic, Inc. Method and apparatus for pulsed iontophoretic drug delivery
US5037381A (en) * 1990-07-27 1991-08-06 Bock C Randolph Electrically assisted transdermal transport device and method for renewing the device

Also Published As

Publication number Publication date
KR940006528B1 (ko) 1994-07-21
NO914893D0 (no) 1991-12-12
KR920016113A (ko) 1992-09-24
US5320597A (en) 1994-06-14
EP0498353A2 (de) 1992-08-12
DE69202872T2 (de) 1995-11-02
DK0498353T3 (da) 1995-10-02
CA2056015C (en) 1995-04-11
MX9200176A (es) 1992-08-01
BR9105499A (pt) 1992-10-27
GR3017405T3 (en) 1995-12-31
CA2056015A1 (en) 1992-08-09
ES2073196T3 (es) 1995-08-01
EP0498353A3 (en) 1992-09-23
ATE123660T1 (de) 1995-06-15
IE67142B1 (en) 1996-03-06
AU644917B2 (en) 1993-12-23
AU8895391A (en) 1992-08-13
JPH067868B2 (ja) 1994-02-02
IE914079A1 (en) 1992-08-12
FI920534A (fi) 1992-08-09
FI920534A0 (fi) 1992-02-07
EP0498353B1 (de) 1995-06-14
NO914893L (no) 1992-08-10
JPH04312471A (ja) 1992-11-04

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: DRUG DELIVERY TECHNOLOGIES, INC., FAIR LAWN, N.J.,

8339 Ceased/non-payment of the annual fee
8327 Change in the person/name/address of the patent owner

Owner name: VYTERIS, INC. (N.D.GES.D. STAATES DELAWARE), FAIR