DE69203551D1 - Biologisch abbaubarer Copolyester von 4-Hydroxyprolin und diesen enthaltende pharmazeutische Zusammensetzung. - Google Patents
Biologisch abbaubarer Copolyester von 4-Hydroxyprolin und diesen enthaltende pharmazeutische Zusammensetzung.Info
- Publication number
- DE69203551D1 DE69203551D1 DE69203551T DE69203551T DE69203551D1 DE 69203551 D1 DE69203551 D1 DE 69203551D1 DE 69203551 T DE69203551 T DE 69203551T DE 69203551 T DE69203551 T DE 69203551T DE 69203551 D1 DE69203551 D1 DE 69203551D1
- Authority
- DE
- Germany
- Prior art keywords
- hydroxyproline
- pharmaceutical composition
- composition containing
- biodegradable copolyester
- chem
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
- C08G63/68—Polyesters containing atoms other than carbon, hydrogen and oxygen
- C08G63/685—Polyesters containing atoms other than carbon, hydrogen and oxygen containing nitrogen
- C08G63/6852—Polyesters containing atoms other than carbon, hydrogen and oxygen containing nitrogen derived from hydroxy carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
- A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP25429091 | 1991-09-06 |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69203551D1 true DE69203551D1 (de) | 1995-08-24 |
DE69203551T2 DE69203551T2 (de) | 1996-01-11 |
Family
ID=17262915
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69203551T Expired - Fee Related DE69203551T2 (de) | 1991-09-06 | 1992-09-01 | Biologisch abbaubarer Copolyester von 4-Hydroxyprolin und diesen enthaltende pharmazeutische Zusammensetzung. |
Country Status (7)
Country | Link |
---|---|
US (1) | US5395916A (de) |
EP (1) | EP0531091B1 (de) |
JP (1) | JPH05202177A (de) |
AT (1) | ATE125278T1 (de) |
DE (1) | DE69203551T2 (de) |
DK (1) | DK0531091T3 (de) |
ES (1) | ES2074828T3 (de) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8765177B2 (en) * | 1997-09-12 | 2014-07-01 | Columbia Laboratories, Inc. | Bioadhesive progressive hydration tablets |
US7153845B2 (en) * | 1998-08-25 | 2006-12-26 | Columbia Laboratories, Inc. | Bioadhesive progressive hydration tablets |
US6372880B1 (en) * | 1997-12-25 | 2002-04-16 | Mitsui Chemicals, Inc. | Copolymer and process for preparing the same |
WO2001010414A1 (en) * | 1999-08-04 | 2001-02-15 | Oakwood Laboratories L.L.C. | Slow release microspheres |
US7265247B1 (en) | 2006-07-28 | 2007-09-04 | Im&T Research, Inc. | Substituted phenylsulfur trifluoride and other like fluorinating agents |
EP2468722B1 (de) * | 2007-03-23 | 2014-10-01 | UBE Industries, Ltd. | Verfahren zur Herstellung von Arylschwefelhalotetrafluoriden |
US8399720B2 (en) * | 2007-03-23 | 2013-03-19 | Ube Industries, Ltd. | Methods for producing fluorinated phenylsulfur pentafluorides |
US8030516B2 (en) * | 2007-10-19 | 2011-10-04 | Ube Industries, Ltd. | Methods for producing perfluoroalkanedi(sulfonyl chloride) |
JP2011518765A (ja) * | 2007-12-11 | 2011-06-30 | 宇部興産株式会社 | ジフルオロメチレン−及びトリフルオロメチル−含有化合物を製造するための方法及び組成物 |
TW201006787A (en) * | 2008-03-07 | 2010-02-16 | Im & T Res Inc | Fluorination processes with arylsulfur halotetrafluorides |
EP2323974A1 (de) * | 2008-08-18 | 2011-05-25 | Ube Industries, Ltd. | Verfahren zur herstellung von fluoralkylsulfinylverbindungen und fluorinierten verbindungen dafür |
EP2334661B1 (de) * | 2008-09-22 | 2017-08-30 | Ube Industries, Ltd. | Verfahren zur herstellung aromatischer poly(pentafluorsulfanyl)-verbindungen |
US20100174096A1 (en) * | 2009-01-05 | 2010-07-08 | Im&T Research, Inc. | Methods for Production of Optically Active Fluoropyrrolidine Derivatives |
US8203003B2 (en) | 2009-01-09 | 2012-06-19 | Ube Industries, Ltd. | 4-fluoropyrrolidine-2-carbonyl fluoride compounds and their preparative methods |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4093709A (en) * | 1975-01-28 | 1978-06-06 | Alza Corporation | Drug delivery devices manufactured from poly(orthoesters) and poly(orthocarbonates) |
USRE30170E (en) * | 1975-04-04 | 1979-12-18 | Sutures, Inc. | Hydrolyzable polymers of amino acid and hydroxy acids |
US4428939A (en) * | 1981-10-16 | 1984-01-31 | Prockop Darwin J | Collagen inhibiting compositions and processes for manufacturing and using same |
JPS61172813A (ja) * | 1985-01-28 | 1986-08-04 | Japan Atom Energy Res Inst | ポリ乳酸を担体とする徐放性複合体の製造方法 |
JPH0720859B2 (ja) * | 1985-02-07 | 1995-03-08 | 武田薬品工業株式会社 | マイクロカプセルの製造法 |
US4831107A (en) * | 1986-07-28 | 1989-05-16 | Semih Erhan | Polymer preparation from lysine and a quinone |
JPS6341416A (ja) * | 1986-08-08 | 1988-02-22 | Takeda Chem Ind Ltd | 鎮痛性ペプチド含有マイクロカプセルの製造法 |
JP2702729B2 (ja) * | 1988-02-24 | 1998-01-26 | エーザイ株式会社 | 徐放性埋込剤 |
CA2046830C (en) * | 1990-07-19 | 1999-12-14 | Patrick P. Deluca | Drug delivery system involving inter-action between protein or polypeptide and hydrophobic biodegradable polymer |
-
1992
- 1992-08-25 JP JP4225763A patent/JPH05202177A/ja active Pending
- 1992-09-01 DE DE69203551T patent/DE69203551T2/de not_active Expired - Fee Related
- 1992-09-01 EP EP92307924A patent/EP0531091B1/de not_active Expired - Lifetime
- 1992-09-01 ES ES92307924T patent/ES2074828T3/es not_active Expired - Lifetime
- 1992-09-01 DK DK92307924.8T patent/DK0531091T3/da active
- 1992-09-01 AT AT92307924T patent/ATE125278T1/de active
-
1993
- 1993-05-17 US US08/062,335 patent/US5395916A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
EP0531091B1 (de) | 1995-07-19 |
EP0531091A1 (de) | 1993-03-10 |
US5395916A (en) | 1995-03-07 |
ATE125278T1 (de) | 1995-08-15 |
JPH05202177A (ja) | 1993-08-10 |
DE69203551T2 (de) | 1996-01-11 |
DK0531091T3 (da) | 1995-09-11 |
ES2074828T3 (es) | 1995-09-16 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |