DE69213800T2 - Oral anzuwendende magensaftstabile Arzneimittel mit gesteuerter Wirkstoffabgabe enthaltend Gallensäuren und deren Salze - Google Patents

Oral anzuwendende magensaftstabile Arzneimittel mit gesteuerter Wirkstoffabgabe enthaltend Gallensäuren und deren Salze

Info

Publication number
DE69213800T2
DE69213800T2 DE69213800T DE69213800T DE69213800T2 DE 69213800 T2 DE69213800 T2 DE 69213800T2 DE 69213800 T DE69213800 T DE 69213800T DE 69213800 T DE69213800 T DE 69213800T DE 69213800 T2 DE69213800 T2 DE 69213800T2
Authority
DE
Germany
Prior art keywords
salts
active ingredients
controlled release
gastric juice
bile acids
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69213800T
Other languages
English (en)
Other versions
DE69213800D1 (de
Inventor
Egidio Marchi
Gianfranco Tamagnone
Leone Gabriele Rotini
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alfa Wasserman SpA
Original Assignee
Alfa Wasserman SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alfa Wasserman SpA filed Critical Alfa Wasserman SpA
Application granted granted Critical
Publication of DE69213800D1 publication Critical patent/DE69213800D1/de
Publication of DE69213800T2 publication Critical patent/DE69213800T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2886—Dragees; Coated pills or tablets, e.g. with film or compression coating having two or more different drug-free coatings; Tablets of the type inert core-drug layer-inactive layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4891—Coated capsules; Multilayered drug free capsule shells
DE69213800T 1991-04-12 1992-04-02 Oral anzuwendende magensaftstabile Arzneimittel mit gesteuerter Wirkstoffabgabe enthaltend Gallensäuren und deren Salze Expired - Fee Related DE69213800T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITBO910114A IT1245891B (it) 1991-04-12 1991-04-12 Formulazioni farmaceutiche a rilascio controllato per uso orale gastroresistenti contenenti acidi biliari e loro sali.

Publications (2)

Publication Number Publication Date
DE69213800D1 DE69213800D1 (de) 1996-10-24
DE69213800T2 true DE69213800T2 (de) 1997-02-20

Family

ID=11337392

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69213800T Expired - Fee Related DE69213800T2 (de) 1991-04-12 1992-04-02 Oral anzuwendende magensaftstabile Arzneimittel mit gesteuerter Wirkstoffabgabe enthaltend Gallensäuren und deren Salze

Country Status (9)

Country Link
US (1) US5300300A (de)
EP (1) EP0508312B1 (de)
JP (1) JP2509046B2 (de)
KR (1) KR970005177B1 (de)
CA (1) CA2065652C (de)
DE (1) DE69213800T2 (de)
ES (1) ES2091970T3 (de)
IT (1) IT1245891B (de)
TW (1) TW215899B (de)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9212511D0 (en) * 1992-06-12 1992-07-22 Cortecs Ltd Pharmaceutical compositions
IT1255968B (it) * 1992-11-27 1995-11-17 Composizioni farmaceutiche contenenti acido ursodesossicolico
IL119660A (en) * 1993-05-10 2002-09-12 Euro Celtique Sa Controlled release formulation comprising tramadol
US5891471A (en) * 1993-11-23 1999-04-06 Euro-Celtique, S.A. Pharmaceutical multiparticulates
KR100354702B1 (ko) * 1993-11-23 2002-12-28 유로-셀티크 소시에떼 아노뉨 약학조성물의제조방법및서방형조성물
US5843480A (en) * 1994-03-14 1998-12-01 Euro-Celtique, S.A. Controlled release diamorphine formulation
GB9422154D0 (en) 1994-11-03 1994-12-21 Euro Celtique Sa Pharmaceutical compositions and method of producing the same
US5965161A (en) 1994-11-04 1999-10-12 Euro-Celtique, S.A. Extruded multi-particulates
DE29717252U1 (de) * 1997-09-26 1998-02-19 Falk Pharma Gmbh Arzneimittelkit aus einem Budesonid-haltigen und einem Ursodesoxycholsäure-haltigen Arzneimittel zur Behandlung von cholestatischen Lebererkrankungen
US20050158408A1 (en) * 1998-07-24 2005-07-21 Yoo Seo H. Dried forms of aqueous solubilized bile acid dosage formulation: preparation and uses thereof
US7303768B2 (en) 1998-07-24 2007-12-04 Seo Hong Yoo Preparation of aqueous clear solution dosage forms with bile acids
US7772220B2 (en) * 2004-10-15 2010-08-10 Seo Hong Yoo Methods and compositions for reducing toxicity of a pharmaceutical compound
EP1113785B1 (de) 1998-07-24 2005-04-13 Seo Hong Yoo Klare wässrige lösungen enthaltend gallensäuren
DE19918325A1 (de) 1999-04-22 2000-10-26 Euro Celtique Sa Verfahren zur Herstellung von Arzneiformen mit regulierter Wirkstofffreisetzung mittels Extrusion
EP1255566A2 (de) * 2000-02-04 2002-11-13 Seo Hong Yoo Herstellung von gallensäuren enthaltenden wässrigen klaren lösungen
US6821931B2 (en) * 2002-03-05 2004-11-23 Alpine Mud Products Corporation Water-based drilling fluid additive containing talc and carrier
US20040241252A1 (en) * 2003-05-29 2004-12-02 Abney Christopher Charles Pharmaceutical compositions for oral administration comprising lithium carbonate, processes of making the same, and methods of administering the same
US7145125B2 (en) * 2003-06-23 2006-12-05 Advanced Optical Technologies, Llc Integrating chamber cone light using LED sources
US20070015796A1 (en) * 2003-09-26 2007-01-18 Smithkline Beecham Corporation Compositions and methods for treatment of fibrosis
US20050181047A1 (en) * 2004-02-18 2005-08-18 Jaime Romero Compositions and methods for timed release of water-soluble nutritional supplements
US7491263B2 (en) * 2004-04-05 2009-02-17 Technology Innovation, Llc Storage assembly
ES2339790T3 (es) * 2004-08-30 2010-05-25 Seo Hong Yoo Efecto neuroprotector de udca solubilizado en modelo isquemico focal.
ATE506955T1 (de) * 2004-10-15 2011-05-15 Seo Hong Yoo Zusammensetzungen zur verringerung der toxizität von cisplatin, carboplatin und oxaliplatin
CA2585471A1 (en) * 2004-11-01 2006-05-11 Seo Hong Yoo Methods and compositions for reducing neurodegeneration in amyotrophic lateral sclerosis
US20060275364A1 (en) * 2005-05-26 2006-12-07 Ahmed Salah U Flexible Solid Dosage Forms and Methods of Making and Using the Same
CA2673665C (en) * 2006-12-22 2017-03-21 Ironwood Pharmaceuticals, Inc. Method and compositions for treating esophageal disorders
KR101636958B1 (ko) * 2009-09-11 2016-07-06 주식회사 대웅제약 우루소데옥시콜린산-합성하이드로탈사이트-유드라짓 혼성체, 이를 함유하는 약학 조성물 및 그 제조방법
US10137094B2 (en) 2011-10-11 2018-11-27 Sun Pharmaceutical Industries Limited Gastroretentive dosage system and process of preparation thereof
US20170119680A1 (en) 2015-10-30 2017-05-04 R.P. Scherer Technologies, Llc Extended release film-coated capsules

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2340060A1 (de) * 1973-08-08 1975-02-20 Scherer Gmbh R P Magensaftresistente gelatinekapseln und verfahren zu deren herstellung
IT1101649B (it) * 1978-12-15 1985-10-07 Lehner Ag Composizione farmaceutica ad azione prolungata contenente acidi biliari
GB2189699A (en) * 1986-04-30 1987-11-04 Haessle Ab Coated acid-labile medicaments
IT1212141B (it) 1987-06-03 1989-11-08 So Ri Far S R L Composizioni farmaceutiche per la prevenzione e terapia della calcolosi delle vie biliari e della dispepsia biliare.

Also Published As

Publication number Publication date
EP0508312B1 (de) 1996-09-18
ITBO910114A0 (it) 1991-04-12
EP0508312A1 (de) 1992-10-14
CA2065652C (en) 1999-01-12
JP2509046B2 (ja) 1996-06-19
ITBO910114A1 (it) 1992-10-12
TW215899B (de) 1993-11-11
JPH0597677A (ja) 1993-04-20
DE69213800D1 (de) 1996-10-24
CA2065652A1 (en) 1992-10-13
KR970005177B1 (ko) 1997-04-14
US5300300A (en) 1994-04-05
IT1245891B (it) 1994-10-25
KR920019360A (ko) 1992-11-19
ES2091970T3 (es) 1996-11-16

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee