DE69224293T2 - Vanadium enthaltende zusammensetzungen - Google Patents

Vanadium enthaltende zusammensetzungen

Info

Publication number
DE69224293T2
DE69224293T2 DE69224293T DE69224293T DE69224293T2 DE 69224293 T2 DE69224293 T2 DE 69224293T2 DE 69224293 T DE69224293 T DE 69224293T DE 69224293 T DE69224293 T DE 69224293T DE 69224293 T2 DE69224293 T2 DE 69224293T2
Authority
DE
Germany
Prior art keywords
compositions
vanadium
vanadium compositions
oxovanadium
monoprotic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69224293T
Other languages
English (en)
Other versions
DE69224293D1 (de
Inventor
John Hugh Mcneill
Hamid Reza Hoveyda
Chris Orvig
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of British Columbia
Original Assignee
University of British Columbia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of British Columbia filed Critical University of British Columbia
Publication of DE69224293D1 publication Critical patent/DE69224293D1/de
Application granted granted Critical
Publication of DE69224293T2 publication Critical patent/DE69224293T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • A61K31/24Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group having an amino or nitro group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/28Compounds containing heavy metals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/555Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
DE69224293T 1991-09-30 1992-09-29 Vanadium enthaltende zusammensetzungen Expired - Fee Related DE69224293T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/767,510 US5300496A (en) 1991-09-30 1991-09-30 Complexed vanadium for the treatment of diabetes mellitus
PCT/EP1992/002235 WO1993006811A2 (en) 1991-09-30 1992-09-29 Vanadium compositions

Publications (2)

Publication Number Publication Date
DE69224293D1 DE69224293D1 (de) 1998-03-05
DE69224293T2 true DE69224293T2 (de) 1998-07-09

Family

ID=25079727

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69224293T Expired - Fee Related DE69224293T2 (de) 1991-09-30 1992-09-29 Vanadium enthaltende zusammensetzungen

Country Status (13)

Country Link
US (1) US5300496A (de)
EP (2) EP0606318B1 (de)
JP (1) JP3515107B2 (de)
AT (1) ATE162716T1 (de)
AU (1) AU2649792A (de)
CA (1) CA2120338A1 (de)
DE (1) DE69224293T2 (de)
DK (1) DK0606318T3 (de)
ES (1) ES2112329T3 (de)
GR (1) GR3026654T3 (de)
NZ (1) NZ244569A (de)
WO (1) WO1993006811A2 (de)
ZA (1) ZA927522B (de)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5866563A (en) * 1991-09-30 1999-02-02 The University Of British Columbia Vanadium compositions
US5527790A (en) * 1991-09-30 1996-06-18 The University Of British Columbia Bis(maltolato)oxovanadium compositions for the treatment of elevated blood sugar
GB9305735D0 (en) * 1993-03-19 1993-05-05 North John R Novel agent for controlling cell activity
US5871779A (en) * 1994-01-18 1999-02-16 Mount Sinai Hospital Corporation Treatment of arthropathies with vanadate compounds or analogues thereof
US5565491A (en) * 1994-01-31 1996-10-15 Bristol-Myers Squibb Company Use of phosphotyrosine phospatase inhibitors for controlling cellular proliferation
GB9416768D0 (en) * 1994-08-18 1994-10-12 Nycomed Innovation Ab Compositions
US5863519A (en) * 1994-08-18 1999-01-26 Nycomed Imaging As Composition and method of MRI using both a positive and a negative contrast agent
GB9416767D0 (en) * 1994-08-18 1994-10-12 Nycomed Innovation Ab Compositions
WO1996005867A2 (en) * 1994-08-18 1996-02-29 Nycomed Imaging A/S Compositions
US5545661A (en) * 1995-05-16 1996-08-13 Eli Lilly And Company Methods for inhibiting bone loss with bis-pyrone oxovanadium compounds
US5547685A (en) * 1995-05-16 1996-08-20 Eli Lilly And Company Methods for inhibiting bone loss with vanadyl sulfate
US5885980A (en) * 1996-06-25 1999-03-23 Enrique G. Gutierrez Composition and method for treating diabetes
US5962030A (en) 1997-03-07 1999-10-05 Akesis Pharmaceuticals, Inc. Dietary supplement and method of treatment for diabetic control
EP0984971A1 (de) * 1997-04-24 2000-03-15 Angiotech Pharmaceuticals, Inc. Vanadiumkomplexe und deren derivate und damit verwandte herstellungsverfahren
US6232340B1 (en) 1997-04-24 2001-05-15 Angiotech Pharmaceuticals, Inc. Vanadium complexes and derivatives thereof and methods related thereto
US6432941B1 (en) * 1998-01-20 2002-08-13 Parker Hughes Institute Vanadium compounds for treating cancer
US6245808B1 (en) * 1998-11-05 2001-06-12 Parker Hughes Institute Oxy-vanadium (IV) complexes having spermicidal activity
CA2344246A1 (en) 1998-09-17 2000-03-23 Akesis Pharmaceuticals, Inc. Combinations of chromium or vanadium with antidiabetics for glucose metabolism disorders
US6376549B1 (en) * 1998-09-17 2002-04-23 Akesis Pharmaceuticals, Inc. Metforimin-containing compositions for the treatment of diabetes
US6287586B1 (en) 1998-09-18 2001-09-11 The University Of British Columbia Pharmaceutical compositions of vanadium biguanide complexes and their use
WO2000024730A1 (en) * 1998-10-28 2000-05-04 The University Of British Columbia Organic vanadium(iii) complexes and their use
GB2396106B (en) * 2002-12-12 2006-11-15 Johnson & Johnson Medical Ltd Wound dressings comprising enzyme inhibitors
CN101068769A (zh) * 2004-07-02 2007-11-07 根梅迪卡治疗公司 治疗和/或预防糖尿病的芳烷基胺钒(v)盐
MX2007007183A (es) * 2004-12-16 2008-01-14 Genmedica Therapeutics Sl Aminas, combinacion de aminas y vanadio y sales de amina y vanadio para el tratamiento o prevencion de dislipidemia.
US20070066682A1 (en) * 2005-07-01 2007-03-22 Exposito Miriam R Arylalkylamine vanadium (V) salts for the treatment and/or prevention of Diabetes mellitus
WO2007131996A1 (en) * 2006-05-12 2007-11-22 Genmedica Therapeutics Sl Meta-xylylenediamine vanadate salts
EP2683374B8 (de) 2011-03-07 2019-11-13 CFM Pharma Holding BV Verwendung von vanadiumverbindungen zur bewahrung der normoglykämie bei einem säuger
WO2012131689A1 (en) 2011-03-25 2012-10-04 Chaudhuri Mihir K Insulin mimetic active comprising oxodiperoxo vanadates and a pharamaceutical composition obtained thereof
EP3988092A4 (de) * 2019-06-24 2022-08-24 Hunan Fangshengtai Medical Technology Co., Ltd. Neue anwendung von metallkomplex
CN111035652B (zh) * 2020-01-08 2021-08-24 辽宁大学 钒酸盐酪蛋白复合物在制备降糖药物中的应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1277599C (en) * 1986-10-16 1990-12-11 Barry I. Posner Vanadium - peroxide compositions as insulin mimickers
FR2619382B1 (fr) * 1987-08-11 1990-05-04 Lazaro Rene Compose organo-mineral de vanadyle, procede d'obtention d'un tel compose, composition pharmaceutique contenant ce compose organo-mineral
JPH02292217A (ja) * 1989-05-08 1990-12-03 Otsuka Pharmaceut Co Ltd 糖尿病治療薬

Also Published As

Publication number Publication date
NZ244569A (en) 1995-04-27
EP0811380A3 (de) 1999-01-20
JP3515107B2 (ja) 2004-04-05
EP0606318A1 (de) 1994-07-20
CA2120338A1 (en) 1993-04-15
ZA927522B (en) 1993-06-16
WO1993006811A2 (en) 1993-04-15
WO1993006811A3 (en) 1993-06-24
GR3026654T3 (en) 1998-07-31
DE69224293D1 (de) 1998-03-05
JPH06511244A (ja) 1994-12-15
ES2112329T3 (es) 1998-04-01
ATE162716T1 (de) 1998-02-15
AU2649792A (en) 1993-05-03
EP0606318B1 (de) 1998-01-28
DK0606318T3 (da) 1998-09-23
US5300496A (en) 1994-04-05
EP0811380A2 (de) 1997-12-10

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee