DE69231486D1 - Zusammensetzung enthaltend pdgf und dexamethason zur förderung von gewebsreparatur und -regenerierung - Google Patents
Zusammensetzung enthaltend pdgf und dexamethason zur förderung von gewebsreparatur und -regenerierungInfo
- Publication number
- DE69231486D1 DE69231486D1 DE69231486T DE69231486T DE69231486D1 DE 69231486 D1 DE69231486 D1 DE 69231486D1 DE 69231486 T DE69231486 T DE 69231486T DE 69231486 T DE69231486 T DE 69231486T DE 69231486 D1 DE69231486 D1 DE 69231486D1
- Authority
- DE
- Germany
- Prior art keywords
- regeneration
- dexamethasone
- composition containing
- tissue repair
- pdgf
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1858—Platelet-derived growth factor [PDGF]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/669,070 US5149691A (en) | 1991-03-12 | 1991-03-12 | Issue repair and regeneration through the use of platelet derived growth factor (pdgf) in combination with dexamethasone |
PCT/US1992/002043 WO1992016181A2 (en) | 1991-03-12 | 1992-03-12 | Composition for promoting tissue repair and regeneration |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69231486D1 true DE69231486D1 (de) | 2000-11-02 |
DE69231486T2 DE69231486T2 (de) | 2001-04-26 |
Family
ID=24684879
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69231486T Expired - Fee Related DE69231486T2 (de) | 1991-03-12 | 1992-03-12 | Zusammensetzung enthaltend pdgf und dexamethason zur förderung von gewebsreparatur und -regenerierung |
Country Status (8)
Country | Link |
---|---|
US (2) | US5149691A (de) |
EP (1) | EP0575484B1 (de) |
JP (1) | JPH07505858A (de) |
AT (1) | ATE196604T1 (de) |
AU (1) | AU656372B2 (de) |
CA (1) | CA2106073C (de) |
DE (1) | DE69231486T2 (de) |
WO (1) | WO1992016181A2 (de) |
Families Citing this family (62)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5149691A (en) * | 1991-03-12 | 1992-09-22 | Creative Biomolecules, Inc. | Issue repair and regeneration through the use of platelet derived growth factor (pdgf) in combination with dexamethasone |
US5770209A (en) * | 1991-08-30 | 1998-06-23 | University Of South Florida | Acceleration of wound healing using connective tissue growth factor |
US5408040A (en) * | 1991-08-30 | 1995-04-18 | University Of South Florida | Connective tissue growth factor(CTGF) |
US7384634B2 (en) * | 1991-08-30 | 2008-06-10 | University Of South Florida | Connective tissue growth factor |
US5837258A (en) * | 1991-08-30 | 1998-11-17 | University Of South Florida | Induction of tissue, bone or cartilage formation using connective tissue growth factor |
US5444151A (en) * | 1992-05-15 | 1995-08-22 | Ludwig Institute For Cancer Research | Platelet derived growth factor antagonists |
US5326695A (en) * | 1992-05-15 | 1994-07-05 | Ludwig Institute For Cancer Research | Platelet derived growth factor agonists |
DE4228457A1 (de) * | 1992-08-27 | 1994-04-28 | Beiersdorf Ag | Herstellung von heterodimerem PDGF-AB mit Hilfe eines bicistronischen Vektorsystems in Säugerzellen |
US5455041A (en) * | 1993-09-13 | 1995-10-03 | Research Foundation Of State University Of New York At Buffalo | Method for inducing periodontal tissue regeneration |
US5942496A (en) * | 1994-02-18 | 1999-08-24 | The Regent Of The University Of Michigan | Methods and compositions for multiple gene transfer into bone cells |
US6551618B2 (en) | 1994-03-15 | 2003-04-22 | University Of Birmingham | Compositions and methods for delivery of agents for neuronal regeneration and survival |
EP0743066A3 (de) * | 1995-05-16 | 1998-09-30 | Mitsui Pharmaceuticals, Inc. | Wundheilmittel |
US5776193A (en) * | 1995-10-16 | 1998-07-07 | Orquest, Inc. | Bone grafting matrix |
US6902584B2 (en) | 1995-10-16 | 2005-06-07 | Depuy Spine, Inc. | Bone grafting matrix |
WO1997045533A1 (en) * | 1996-05-28 | 1997-12-04 | The Regents Of The University Of Michigan | Engineering oral tissues |
DE19754140A1 (de) * | 1997-12-05 | 1999-06-24 | Era Beschichtung Gmbh & Co Kg | Innenraummaterial auf der Basis von Kunststoff, Verfahren zu dessen Herstellung und Verwendung desselben |
WO1999066797A1 (en) | 1998-06-22 | 1999-12-29 | Worden Charles E | Enriched platelet wound healant |
AU1430601A (en) * | 1999-11-02 | 2001-05-14 | Eli Lilly And Company | Methods of using lp8, a pdgf-related protein, to treat musculoskeletal disorders |
WO2002070731A2 (en) | 2001-03-05 | 2002-09-12 | Visible Genetics Inc. | Methods and primers for evaluating hiv-1 mutations |
EP1531837A4 (de) * | 2001-06-07 | 2006-11-15 | Chiou Consulting Inc | ZUSAMMENSETZUNGEN UND VERFAHREN FüR DIE PROPHYLAXE UND BEHANDLUNG VON APHTHEN UND HERPES-SIMPLEX-LÄSIONEN |
US7819888B2 (en) * | 2001-10-23 | 2010-10-26 | Innovasive Devices, Inc. | Method and apparatus for harvesting and implanting bone plugs |
DE10152956A1 (de) * | 2001-10-26 | 2003-05-15 | Fresenius Kabi De Gmbh | Pharmazeutische Zusammensetzung, einen Wachstumsfaktor und/oder ein Zytokin und ein antiseptisches Biguanid umfassend |
JP2005530768A (ja) * | 2002-05-09 | 2005-10-13 | メディジーンズ | 血漿または血清を含有した創傷治療用医薬組成物 |
US20040018220A1 (en) * | 2002-07-26 | 2004-01-29 | Chiou Consulting, Inc. | Aqueous compositions for facial cosmetics |
US6616923B1 (en) * | 2002-07-26 | 2003-09-09 | Chiou Consulting, Inc. | Aqueous compositions for facial cosmetics |
CA2518667C (en) | 2003-03-14 | 2011-07-19 | The Trustees Of Columbia University In The City Of New York | Systems and methods of blood-based therapies having a microfluidic membraneless exchange device |
US20060076295A1 (en) | 2004-03-15 | 2006-04-13 | The Trustees Of Columbia University In The City Of New York | Systems and methods of blood-based therapies having a microfluidic membraneless exchange device |
US7309232B2 (en) * | 2003-10-10 | 2007-12-18 | Dentigenix Inc. | Methods for treating dental conditions using tissue scaffolds |
US7258875B2 (en) * | 2003-12-04 | 2007-08-21 | Chiou Consulting, Inc. | Compositions and methods for topical treatment of skin infection |
US8293890B2 (en) | 2004-04-30 | 2012-10-23 | Advanced Cardiovascular Systems, Inc. | Hyaluronic acid based copolymers |
GB0414803D0 (en) * | 2004-07-01 | 2004-08-04 | Glaxo Group Ltd | Composition |
US7473678B2 (en) | 2004-10-14 | 2009-01-06 | Biomimetic Therapeutics, Inc. | Platelet-derived growth factor compositions and methods of use thereof |
US20060115266A1 (en) * | 2004-12-01 | 2006-06-01 | Gil Levi | All-optical protection signaling systems and methods in optical communication networks |
WO2007016620A2 (en) * | 2005-08-01 | 2007-02-08 | Genera Doo | Methods and compositions for regenerating articular cartilage |
CA2630077C (en) | 2005-11-17 | 2014-07-15 | Biomimetic Therapeutics, Inc. | Maxillofacial bone augmentation using rhpdgf-bb and a biocompatible matrix |
EP1976864B1 (de) | 2006-01-23 | 2012-09-26 | Imagene Co., Ltd. | Neues peptid und seine verwendung |
EP2311505B1 (de) * | 2006-02-09 | 2013-11-06 | BioMimetic Therapeutics, LLC | Zusammensetzungen und Verfahren zur Behandlung von Knochen |
JP2010506599A (ja) | 2006-05-22 | 2010-03-04 | ザ トラスティーズ オブ コロンビア ユニバーシティ イン ザ シティ オブ ニューヨーク | 第1流体と第2流体との間で成分を交換する方法、第1流体から第1成分を清浄する方法、血液の処理方法、流体処理装置、第1流体と第1及び第2成分を含む第2流体との間で成分を交換する装置、第1流体と第2流体との間で成分を交換する装置、血漿から血球を分離する方法 |
AU2007269712B2 (en) | 2006-06-30 | 2013-02-07 | Biomimetic Therapeutics, Llc | PDGF-biomatrix compositions and methods for treating rotator cuff injuries |
US9161967B2 (en) | 2006-06-30 | 2015-10-20 | Biomimetic Therapeutics, Llc | Compositions and methods for treating the vertebral column |
US8106008B2 (en) | 2006-11-03 | 2012-01-31 | Biomimetic Therapeutics, Inc. | Compositions and methods for arthrodetic procedures |
AU2013203287B2 (en) * | 2006-11-03 | 2015-12-17 | Biomimetic Therapeutics, Llc. | Compositions and methods for arthrodetic procedures |
US9511076B2 (en) * | 2008-05-30 | 2016-12-06 | Clarion Research Group | Formulations and methods for recovery from dental surgery |
US8282963B2 (en) * | 2007-10-15 | 2012-10-09 | The Regents Of The University Of Colorado, A Body Corporate | Methods for extracting platelets and compositions obtained therefrom |
MX2010007442A (es) | 2008-01-07 | 2010-12-21 | Vereniging Voor Christelijk Hoger Onderwijs Wetenschappelijk Onderzoek En Patientenzorg | Uso de peptidos para promover la curacion de heridas. |
WO2009100154A1 (en) | 2008-02-04 | 2009-08-13 | Trustees Of Columbia University In The City Of New York | Fluid separation devices, systems and methods |
RU2010137106A (ru) | 2008-02-07 | 2012-03-20 | Байомайметик Терапьютикс, Инк. (Us) | Композиции и способы для дистракциионного остеогенеза |
EP2341951A2 (de) | 2008-09-09 | 2011-07-13 | BioMimetic Therapeutics, Inc. | Aus thrombozyten stammende wachstumsfaktor-zusammensetzungen und verfahren zur behandlung von sehnen- und bänderverletzungen |
US20120100111A1 (en) * | 2009-03-06 | 2012-04-26 | Universite Paris Descartes | Method for treating cancer |
CN102811622A (zh) | 2010-02-22 | 2012-12-05 | 生物模拟治疗公司 | 用于治疗腱病的血小板衍生生长因子组合物和方法 |
AU2011267081A1 (en) | 2010-06-14 | 2013-01-17 | Gene Signal International Sa | Novel peptides for wound healing |
US8288334B2 (en) | 2010-06-14 | 2012-10-16 | Gene Signal International Sa | Peptides for wound healing |
ES2410804T3 (es) | 2010-06-14 | 2013-07-03 | Gene Signal International Sa | Péptidos para la curación de heridas |
WO2012021249A2 (en) | 2010-07-12 | 2012-02-16 | Atyr Pharma, Inc. | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of histidyl-trna synthetases |
US20130108683A1 (en) * | 2011-10-25 | 2013-05-02 | Biomimetic Therapeutics, Inc. | Compositions and methods for treating partial and full thickness wounds and injuries |
EP2814514B1 (de) | 2012-02-16 | 2017-09-13 | Atyr Pharma, Inc. | Histidyl-trna-synthetasen zur behandlung von autoimmun- und entzündungserkrankungen |
US9587235B2 (en) | 2013-03-15 | 2017-03-07 | Atyr Pharma, Inc. | Histidyl-tRNA synthetase-Fc conjugates |
JP6871855B2 (ja) | 2014-10-14 | 2021-05-19 | サムエル リンチ, | 創傷を処置するための組成物 |
AU2018256435A1 (en) | 2017-04-20 | 2019-11-07 | Atyr Pharma, Inc. | Compositions and methods for treating lung inflammation |
KR20200060997A (ko) | 2018-11-23 | 2020-06-02 | (주)메디코스바이오텍 | 창상치료용 약학조성물 |
CZ308845B6 (cs) | 2019-01-21 | 2021-07-07 | Globetech Innovation S.R.O | Farmaceutická směs topicky hojivých peptidových složek pro použití k topické léčbě kožních defektů a/nebo k topickému hojení ran |
PL433169A1 (pl) | 2020-03-06 | 2021-09-13 | Gdański Uniwersytet Medyczny | Lipopeptydowe koniugaty i ich sole, sposób wytwarzania lipopeptydowych koniugatów i ich soli, kompozycja farmaceutyczna zawierająca lipopeptydowy koniugat i jego sole do leczenia ran przewlekłych |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS6028999A (ja) * | 1983-06-30 | 1985-02-14 | Maruho Kk | 細胞増殖促進作用を有するたんぱく質、その組成物と製造方法 |
US4957742A (en) * | 1984-11-29 | 1990-09-18 | Regents Of The University Of Minnesota | Method for promoting hair growth |
US4861757A (en) * | 1986-11-14 | 1989-08-29 | Institute Of Molecular Biology | Wound healing and bone regeneration using PDGF and IGF-I |
US5124316A (en) * | 1986-11-14 | 1992-06-23 | President And Fellows Of Harvard College | Method for periodontal regeneration |
EP0292517B1 (de) * | 1986-12-11 | 1992-09-09 | Btg International Limited | Verbesserungen im gebrauch oder in bezug auf den gebrauch von egf |
US4808402A (en) * | 1987-05-29 | 1989-02-28 | Northwestern University | Method and compositions for modulating neovascularization |
US4874746A (en) * | 1987-12-22 | 1989-10-17 | Institute Of Molecular Biology, Inc. | Wound headling composition of TGF-alpha and PDGF |
AU657472B2 (en) * | 1990-03-06 | 1995-03-16 | Claude Paul Genero | Towel or blanket support device |
US5149691A (en) * | 1991-03-12 | 1992-09-22 | Creative Biomolecules, Inc. | Issue repair and regeneration through the use of platelet derived growth factor (pdgf) in combination with dexamethasone |
CA2108120C (en) * | 1991-04-12 | 1997-03-25 | Marc F. Charette | Method of treating gastrointestinal ulcers with platelet derived growth factor |
-
1991
- 1991-03-12 US US07/669,070 patent/US5149691A/en not_active Expired - Fee Related
-
1992
- 1992-03-12 AT AT92908042T patent/ATE196604T1/de not_active IP Right Cessation
- 1992-03-12 EP EP92908042A patent/EP0575484B1/de not_active Expired - Lifetime
- 1992-03-12 AU AU15591/92A patent/AU656372B2/en not_active Ceased
- 1992-03-12 JP JP4507585A patent/JPH07505858A/ja active Pending
- 1992-03-12 CA CA002106073A patent/CA2106073C/en not_active Expired - Fee Related
- 1992-03-12 DE DE69231486T patent/DE69231486T2/de not_active Expired - Fee Related
- 1992-03-12 US US07/849,931 patent/US5376636A/en not_active Expired - Fee Related
- 1992-03-12 WO PCT/US1992/002043 patent/WO1992016181A2/en active IP Right Grant
Also Published As
Publication number | Publication date |
---|---|
US5149691A (en) | 1992-09-22 |
WO1992016181A3 (en) | 1992-11-12 |
EP0575484A1 (de) | 1993-12-29 |
ATE196604T1 (de) | 2000-10-15 |
CA2106073A1 (en) | 1993-09-13 |
AU656372B2 (en) | 1995-02-02 |
WO1992016181A2 (en) | 1992-10-01 |
CA2106073C (en) | 2003-09-30 |
EP0575484B1 (de) | 2000-09-27 |
US5376636A (en) | 1994-12-27 |
DE69231486T2 (de) | 2001-04-26 |
JPH07505858A (ja) | 1995-06-29 |
AU1559192A (en) | 1992-10-21 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |