DE69231608T2 - Verfahren und mittel für die analyse von genetischem polymorphismus des angiotensin-umwandlungs-enzyms i - Google Patents
Verfahren und mittel für die analyse von genetischem polymorphismus des angiotensin-umwandlungs-enzyms iInfo
- Publication number
- DE69231608T2 DE69231608T2 DE69231608T DE69231608T DE69231608T2 DE 69231608 T2 DE69231608 T2 DE 69231608T2 DE 69231608 T DE69231608 T DE 69231608T DE 69231608 T DE69231608 T DE 69231608T DE 69231608 T2 DE69231608 T2 DE 69231608T2
- Authority
- DE
- Germany
- Prior art keywords
- pct
- genetic polymorphism
- conversion enzyme
- analyzing genetic
- angiotensin conversion
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 238000000034 method Methods 0.000 title abstract 3
- 102000015427 Angiotensins Human genes 0.000 title 1
- 108010064733 Angiotensins Proteins 0.000 title 1
- 102000004190 Enzymes Human genes 0.000 title 1
- 108090000790 Enzymes Proteins 0.000 title 1
- 206010071602 Genetic polymorphism Diseases 0.000 title 1
- 238000006243 chemical reaction Methods 0.000 title 1
- UUUHXMGGBIUAPW-UHFFFAOYSA-N 1-[1-[2-[[5-amino-2-[[1-[5-(diaminomethylideneamino)-2-[[1-[3-(1h-indol-3-yl)-2-[(5-oxopyrrolidine-2-carbonyl)amino]propanoyl]pyrrolidine-2-carbonyl]amino]pentanoyl]pyrrolidine-2-carbonyl]amino]-5-oxopentanoyl]amino]-3-methylpentanoyl]pyrrolidine-2-carbon Chemical compound C1CCC(C(=O)N2C(CCC2)C(O)=O)N1C(=O)C(C(C)CC)NC(=O)C(CCC(N)=O)NC(=O)C1CCCN1C(=O)C(CCCN=C(N)N)NC(=O)C1CCCN1C(=O)C(CC=1C2=CC=CC=C2NC=1)NC(=O)C1CCC(=O)N1 UUUHXMGGBIUAPW-UHFFFAOYSA-N 0.000 abstract 1
- 101000773743 Homo sapiens Angiotensin-converting enzyme Proteins 0.000 abstract 1
- 108090000882 Peptidyl-Dipeptidase A Proteins 0.000 abstract 1
- 102000004270 Peptidyl-Dipeptidase A Human genes 0.000 abstract 1
- 230000003321 amplification Effects 0.000 abstract 1
- 238000003199 nucleic acid amplification method Methods 0.000 abstract 1
- 239000002773 nucleotide Substances 0.000 abstract 1
- 125000003729 nucleotide group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9108020A FR2678285A1 (fr) | 1991-06-27 | 1991-06-27 | Moyens et procedes pour l'etude du polymorphisme genetique de l'enzyme de conversion de l'angiotensine 1. |
| PCT/FR1992/000574 WO1993000360A1 (fr) | 1991-06-27 | 1992-06-24 | Moyens et procedes pour l'etude du polymorphisme genetique de l'enzyme de conversion de l'angiotensine i |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69231608D1 DE69231608D1 (de) | 2001-01-25 |
| DE69231608T2 true DE69231608T2 (de) | 2001-06-13 |
Family
ID=9414424
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69231608T Expired - Fee Related DE69231608T2 (de) | 1991-06-27 | 1992-06-24 | Verfahren und mittel für die analyse von genetischem polymorphismus des angiotensin-umwandlungs-enzyms i |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US5736323A (de) |
| EP (1) | EP0591332B1 (de) |
| JP (1) | JPH06508524A (de) |
| AT (1) | ATE198219T1 (de) |
| CA (1) | CA2111953A1 (de) |
| DE (1) | DE69231608T2 (de) |
| FR (1) | FR2678285A1 (de) |
| WO (1) | WO1993000360A1 (de) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2723590B1 (fr) * | 1994-08-09 | 1996-10-25 | Inst Nat Sante Rech Med | Procede de detection et trousse de diagnostic in vitro d'une predisposition a l'infarctus du myocarde |
| US6197505B1 (en) * | 1997-04-04 | 2001-03-06 | Pyrosequencing Ab | Methods for assessing cardiovascular status and compositions for use thereof |
| US6194556B1 (en) * | 1997-12-11 | 2001-02-27 | Millennium Pharmaceuticals, Inc. | Angiotensin converting enzyme homolog and therapeutic and diagnostic uses therfor |
| US6610497B1 (en) * | 1997-12-11 | 2003-08-26 | Millennium Pharmaceuticals, Inc. | Angiotensin converting enzyme homolog and therapeutic and diagnostic uses therefor |
| AU4518399A (en) * | 1998-06-30 | 2000-01-17 | University Of Wales College Of Medicine | Alzheimer's disease |
| US7514213B2 (en) * | 2002-11-15 | 2009-04-07 | Quest Diagnostics Investments Incorporated | Compositions and methods for determining genotypes |
| US7794933B1 (en) | 2005-01-04 | 2010-09-14 | Myriad Genetics, Inc. | Depression-related gene |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2636968B1 (fr) * | 1988-09-27 | 1992-01-03 | Inst Nat Sante Rech Med | Acide nucleique codant pour l'enzyme de conversion de l'angiotensine (eca) humaine, et ses applications, notamment pour le diagnostic in vitro de l'hypertension arterielle |
| FR2649412B1 (fr) * | 1989-07-05 | 1995-10-20 | Inst Nat Sante Rech Med | Acide nucleique codant pour l'enzyme de conversion de l'angiotensine (eca) testiculaire humaine, et ses applications, notamment pour le depistage in vitro de cette enzyme dans l'organisme |
-
1991
- 1991-06-27 FR FR9108020A patent/FR2678285A1/fr active Granted
-
1992
- 1992-06-24 AT AT92913338T patent/ATE198219T1/de not_active IP Right Cessation
- 1992-06-24 US US08/157,171 patent/US5736323A/en not_active Expired - Fee Related
- 1992-06-24 EP EP92913338A patent/EP0591332B1/de not_active Expired - Lifetime
- 1992-06-24 DE DE69231608T patent/DE69231608T2/de not_active Expired - Fee Related
- 1992-06-24 WO PCT/FR1992/000574 patent/WO1993000360A1/fr active IP Right Grant
- 1992-06-24 CA CA002111953A patent/CA2111953A1/fr not_active Abandoned
- 1992-06-24 JP JP5501362A patent/JPH06508524A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| FR2678285A1 (fr) | 1992-12-31 |
| DE69231608D1 (de) | 2001-01-25 |
| JPH06508524A (ja) | 1994-09-29 |
| ATE198219T1 (de) | 2001-01-15 |
| US5736323A (en) | 1998-04-07 |
| WO1993000360A1 (fr) | 1993-01-07 |
| FR2678285B1 (de) | 1994-08-19 |
| EP0591332A1 (de) | 1994-04-13 |
| CA2111953A1 (fr) | 1993-01-07 |
| EP0591332B1 (de) | 2000-12-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |