DE69233657D1 - Drei polymorphe dns-marker mit repetitiven mikrosatellitensequenzen mit hoher informationsdichte - Google Patents
Drei polymorphe dns-marker mit repetitiven mikrosatellitensequenzen mit hoher informationsdichteInfo
- Publication number
- DE69233657D1 DE69233657D1 DE69233657T DE69233657T DE69233657D1 DE 69233657 D1 DE69233657 D1 DE 69233657D1 DE 69233657 T DE69233657 T DE 69233657T DE 69233657 T DE69233657 T DE 69233657T DE 69233657 D1 DE69233657 D1 DE 69233657D1
- Authority
- DE
- Germany
- Prior art keywords
- segments
- markers
- pcr
- assay
- differences
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6858—Allele-specific amplification
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US70750191A | 1991-05-29 | 1991-05-29 | |
| US707501 | 1991-05-29 | ||
| US799828 | 1991-11-27 | ||
| US07/799,828 US5378602A (en) | 1991-05-29 | 1991-11-27 | Highly informative microsatellite repeat polymorphic DNA markers twenty-[seven]six |
| PCT/US1992/004195 WO1992021693A1 (en) | 1991-05-29 | 1992-05-27 | Three highly informative microsatellite repeat polymorphic dna markers |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69233657D1 true DE69233657D1 (de) | 2006-10-26 |
| DE69233657T2 DE69233657T2 (de) | 2007-01-11 |
Family
ID=27107900
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69233657T Expired - Lifetime DE69233657T2 (de) | 1991-05-29 | 1992-05-27 | Drei Mikrosatelliten-Repeat-Polymorphe DNA-Marker mit hoher Informationsdichte |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US5378602A (de) |
| EP (1) | EP0663923B1 (de) |
| JP (1) | JPH06509222A (de) |
| AT (1) | ATE339435T1 (de) |
| AU (1) | AU663509B2 (de) |
| DE (1) | DE69233657T2 (de) |
| ES (1) | ES2268682T3 (de) |
| WO (1) | WO1992021693A1 (de) |
Families Citing this family (53)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5861504A (en) * | 1991-05-29 | 1999-01-19 | The United States Of America As Represented By The Department Of Health And Human Services | Eleven highly informative microsatelite repeat polymorphic DNA markers |
| US5378602A (en) * | 1991-05-29 | 1995-01-03 | The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Highly informative microsatellite repeat polymorphic DNA markers twenty-[seven]six |
| US5650277A (en) * | 1992-07-02 | 1997-07-22 | Diagenetics Ltd. | Method of determining the presence and quantifying the number of di- and trinucleotide repeats |
| US5484909A (en) * | 1993-09-10 | 1996-01-16 | Amoco Corporation | Nucleic acid probes for the detection of bacteria of the genera Pediococcus and Lactobacillus and methods for the detection of the bacterial agents causing spoilage of beer |
| FR2711672B1 (fr) * | 1993-10-29 | 1995-12-08 | France Etat Armement | Procédé de sélection et/ou d'obtention de sondes capables de détecter de nouvelles régions à nombre variable de répétitions en tandem, sondes pouvant être ainsi obtenues et leurs utilisations. |
| GB9326052D0 (en) * | 1993-12-21 | 1994-02-23 | Zeneca Ltd | Sequences |
| WO1995033075A1 (en) * | 1994-05-31 | 1995-12-07 | Cornell Research Foundation, Inc. | A method for the identification of nucleic acid samples from dna-containing organisms |
| CA2118048C (en) * | 1994-09-30 | 2003-04-08 | James W. Schumm | Multiplex amplification of short tandem repeat loci |
| US5635351A (en) * | 1995-03-14 | 1997-06-03 | The Regents Of The University Of California | Genetic gain and loss in gliomas |
| US5670325A (en) * | 1996-08-14 | 1997-09-23 | Exact Laboratories, Inc. | Method for the detection of clonal populations of transformed cells in a genomically heterogeneous cellular sample |
| US5741650A (en) * | 1996-01-30 | 1998-04-21 | Exact Laboratories, Inc. | Methods for detecting colon cancer from stool samples |
| WO1997033000A1 (en) * | 1996-03-04 | 1997-09-12 | Genetrace Systems, Inc. | Methods of screening nucleic acids using mass spectrometry |
| US6100029A (en) * | 1996-08-14 | 2000-08-08 | Exact Laboratories, Inc. | Methods for the detection of chromosomal aberrations |
| US6300077B1 (en) | 1996-08-14 | 2001-10-09 | Exact Sciences Corporation | Methods for the detection of nucleic acids |
| US5952178A (en) | 1996-08-14 | 1999-09-14 | Exact Laboratories | Methods for disease diagnosis from stool samples |
| US6020137A (en) * | 1996-08-14 | 2000-02-01 | Exact Laboratories, Inc. | Methods for the detection of loss of heterozygosity |
| US5928870A (en) * | 1997-06-16 | 1999-07-27 | Exact Laboratories, Inc. | Methods for the detection of loss of heterozygosity |
| US6203993B1 (en) | 1996-08-14 | 2001-03-20 | Exact Science Corp. | Methods for the detection of nucleic acids |
| US6146828A (en) * | 1996-08-14 | 2000-11-14 | Exact Laboratories, Inc. | Methods for detecting differences in RNA expression levels and uses therefor |
| CA2275865C (en) * | 1996-08-28 | 2006-12-12 | The Johns Hopkins University School Of Medicine | Method for detecting cell proliferative disorders |
| WO1998008981A1 (en) * | 1996-08-30 | 1998-03-05 | Life Technologies, Inc. | METHODS FOR IDENTIFICATION AND ISOLATION OF SPECIFIC NUCLEOTIDE SEQUENCES IN cDNA AND GENOMIC DNA |
| US5965363A (en) | 1996-09-19 | 1999-10-12 | Genetrace Systems Inc. | Methods of preparing nucleic acids for mass spectrometric analysis |
| EP0963443B1 (de) | 1996-12-10 | 2006-03-08 | Sequenom, Inc. | Abspaltbare, nicht-flüchtige moleküle zur massenmarkierung |
| US6306588B1 (en) | 1997-02-07 | 2001-10-23 | Invitrogen Corporation | Polymerases for analyzing or typing polymorphic nucleic acid fragments and uses thereof |
| US6268136B1 (en) | 1997-06-16 | 2001-07-31 | Exact Science Corporation | Methods for stool sample preparation |
| US6406857B1 (en) | 1997-06-16 | 2002-06-18 | Exact Sciences Corporation | Methods for stool sample preparation |
| WO1999014375A2 (en) * | 1997-09-19 | 1999-03-25 | Genetrace Systems, Inc. | Dna typing by mass spectrometry with polymorphic dna repeat markers |
| US6764822B1 (en) | 1997-09-19 | 2004-07-20 | Sequenom, Inc. | DNA typing by mass spectrometry with polymorphic DNA repeat markers |
| US6544730B1 (en) | 1997-10-27 | 2003-04-08 | Prescott Deininger | High density polymorphic genetic locus |
| US20020064792A1 (en) * | 1997-11-13 | 2002-05-30 | Lincoln Stephen E. | Database for storage and analysis of full-length sequences |
| US6104028A (en) * | 1998-05-29 | 2000-08-15 | Genetrace Systems Inc. | Volatile matrices for matrix-assisted laser desorption/ionization mass spectrometry |
| US6280947B1 (en) | 1999-08-11 | 2001-08-28 | Exact Sciences Corporation | Methods for detecting nucleotide insertion or deletion using primer extension |
| US6503718B2 (en) | 1999-01-10 | 2003-01-07 | Exact Sciences Corporation | Methods for detecting mutations using primer extension for detecting disease |
| US6733965B2 (en) * | 1999-01-15 | 2004-05-11 | International Paper Company | Microsatellite DNA markers and uses thereof |
| AU2407600A (en) * | 1999-01-15 | 2000-08-01 | Craig S. Echt | Microsatellite dna markers and uses thereof |
| US6153389A (en) * | 1999-02-22 | 2000-11-28 | Haarer; Brian K. | DNA additives as a mechanism for unambiguously marking biological samples |
| DE60028732T2 (de) | 1999-02-25 | 2007-06-14 | Exact Sciences Corp., Maynard | Verfahren zur erhaltung der dns-integrität |
| AU767983B2 (en) | 1999-04-09 | 2003-11-27 | Esoterix Genetic Laboratories, Llc | Methods for detecting nucleic acids indicative of cancer |
| AU5008900A (en) * | 1999-05-12 | 2000-11-21 | Invitrogen Corporation | Compositions and methods for enhanced sensitivity and specificity of nucleic acid synthesis |
| US6849403B1 (en) | 1999-09-08 | 2005-02-01 | Exact Sciences Corporation | Apparatus and method for drug screening |
| US6586177B1 (en) * | 1999-09-08 | 2003-07-01 | Exact Sciences Corporation | Methods for disease detection |
| US6919174B1 (en) | 1999-12-07 | 2005-07-19 | Exact Sciences Corporation | Methods for disease detection |
| CA2394921A1 (en) * | 1999-12-07 | 2001-06-14 | Anthony P. Shuber | Supracolonic aerodigestive neoplasm detection |
| ATE305793T1 (de) * | 2000-07-25 | 2005-10-15 | Us Gov Health & Human Serv | Bakteriophage mit breitem wirtspektrum |
| US20050272085A1 (en) * | 2000-09-06 | 2005-12-08 | Hodge Timothy A | Methods for forensic and congenic screening |
| WO2003071252A2 (en) | 2002-02-15 | 2003-08-28 | Exact Sciences Corporation | Methods for analysis of molecular events |
| US20040259101A1 (en) * | 2003-06-20 | 2004-12-23 | Shuber Anthony P. | Methods for disease screening |
| WO2005111244A2 (en) * | 2004-05-10 | 2005-11-24 | Exact Sciences Corporation | Methods for detecting a mutant nucleic acid |
| WO2005113769A1 (en) * | 2004-05-14 | 2005-12-01 | Exact Sciences Corporation | Method for stabilizing biological samples for nucleic acid analysis |
| US7981607B2 (en) * | 2004-08-27 | 2011-07-19 | Esoterix Genetic Laboratories LLC | Method for detecting recombinant event |
| US9109256B2 (en) | 2004-10-27 | 2015-08-18 | Esoterix Genetic Laboratories, Llc | Method for monitoring disease progression or recurrence |
| US9777314B2 (en) * | 2005-04-21 | 2017-10-03 | Esoterix Genetic Laboratories, Llc | Analysis of heterogeneous nucleic acid samples |
| WO2007002383A2 (en) * | 2005-06-24 | 2007-01-04 | Transnetyx, Inc. | Methods for forensic and congenic screening |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4683195A (en) * | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
| US4683202A (en) * | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| US4800159A (en) * | 1986-02-07 | 1989-01-24 | Cetus Corporation | Process for amplifying, detecting, and/or cloning nucleic acid sequences |
| US4879214A (en) * | 1988-11-15 | 1989-11-07 | E. I. Du Pont De Nemours And Company | Differentiation of nucleic acid segments on the basis of nucleotide differences |
| GB2228086A (en) * | 1988-11-25 | 1990-08-15 | Ici Plc | Characterisation of genomic DNA |
| US5001050A (en) * | 1989-03-24 | 1991-03-19 | Consejo Superior Investigaciones Cientificas | PHφ29 DNA polymerase |
| US5028249A (en) * | 1990-12-10 | 1991-07-02 | Emhart Industries, Inc. | Plunger mechanism for i.s. machine |
| DE69231903T2 (de) * | 1991-01-04 | 2001-10-31 | Univ St Louis | Mit isoliertem empfindlichem x-syndrom verbundene dns-sequenzen |
| NL9100132A (nl) * | 1991-01-25 | 1992-08-17 | Ingeny Bv | Werkwijze voor het detecteren van dna sequentievariatie. |
| US5378602A (en) * | 1991-05-29 | 1995-01-03 | The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Highly informative microsatellite repeat polymorphic DNA markers twenty-[seven]six |
-
1991
- 1991-11-27 US US07/799,828 patent/US5378602A/en not_active Expired - Lifetime
-
1992
- 1992-05-27 DE DE69233657T patent/DE69233657T2/de not_active Expired - Lifetime
- 1992-05-27 AU AU21569/92A patent/AU663509B2/en not_active Expired
- 1992-05-27 AT AT92912797T patent/ATE339435T1/de not_active IP Right Cessation
- 1992-05-27 JP JP5500444A patent/JPH06509222A/ja active Pending
- 1992-05-27 EP EP92912797A patent/EP0663923B1/de not_active Expired - Lifetime
- 1992-05-27 ES ES92912797T patent/ES2268682T3/es not_active Expired - Lifetime
- 1992-05-27 WO PCT/US1992/004195 patent/WO1992021693A1/en active IP Right Grant
- 1992-07-31 US US07/922,723 patent/US5369004A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP0663923A4 (de) | 1999-08-04 |
| EP0663923B1 (de) | 2006-09-13 |
| ES2268682T3 (es) | 2007-03-16 |
| DE69233657T2 (de) | 2007-01-11 |
| AU663509B2 (en) | 1995-10-12 |
| US5378602A (en) | 1995-01-03 |
| US5369004A (en) | 1994-11-29 |
| WO1992021693A1 (en) | 1992-12-10 |
| EP0663923A1 (de) | 1995-07-26 |
| AU2156992A (en) | 1993-01-08 |
| JPH06509222A (ja) | 1994-10-20 |
| ATE339435T1 (de) | 2006-10-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| R071 | Expiry of right |
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