DE69301750T2 - Verwendung von 1-Alpha,24(R)-Dihydroxy-22(E)-Dehydrovitamin-D3 zur Herstellung eines Arzneimittels zur Behandlung der Osteoporose - Google Patents

Verwendung von 1-Alpha,24(R)-Dihydroxy-22(E)-Dehydrovitamin-D3 zur Herstellung eines Arzneimittels zur Behandlung der Osteoporose

Info

Publication number
DE69301750T2
DE69301750T2 DE69301750T DE69301750T DE69301750T2 DE 69301750 T2 DE69301750 T2 DE 69301750T2 DE 69301750 T DE69301750 T DE 69301750T DE 69301750 T DE69301750 T DE 69301750T DE 69301750 T2 DE69301750 T2 DE 69301750T2
Authority
DE
Germany
Prior art keywords
dihydroxy
alpha
osteoporosis
dehydrovitamin
medicament
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69301750T
Other languages
English (en)
Other versions
DE69301750D1 (de
Inventor
Hector Floyd Deluca
Heinrich Konstantine Schnoes
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wisconsin Alumni Research Foundation
Original Assignee
Wisconsin Alumni Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wisconsin Alumni Research Foundation filed Critical Wisconsin Alumni Research Foundation
Application granted granted Critical
Publication of DE69301750D1 publication Critical patent/DE69301750D1/de
Publication of DE69301750T2 publication Critical patent/DE69301750T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/59Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • A61K31/5939,10-Secocholestane derivatives, e.g. cholecalciferol, i.e. vitamin D3
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/59Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/02Nutrients, e.g. vitamins, minerals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
DE69301750T 1992-04-24 1993-04-26 Verwendung von 1-Alpha,24(R)-Dihydroxy-22(E)-Dehydrovitamin-D3 zur Herstellung eines Arzneimittels zur Behandlung der Osteoporose Expired - Fee Related DE69301750T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US87337492A 1992-04-24 1992-04-24

Publications (2)

Publication Number Publication Date
DE69301750D1 DE69301750D1 (de) 1996-04-18
DE69301750T2 true DE69301750T2 (de) 1996-07-25

Family

ID=25361517

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69301750T Expired - Fee Related DE69301750T2 (de) 1992-04-24 1993-04-26 Verwendung von 1-Alpha,24(R)-Dihydroxy-22(E)-Dehydrovitamin-D3 zur Herstellung eines Arzneimittels zur Behandlung der Osteoporose

Country Status (10)

Country Link
US (1) US5395830A (de)
EP (1) EP0567352B1 (de)
JP (1) JP2769960B2 (de)
KR (1) KR940005275A (de)
AT (1) ATE135220T1 (de)
AU (1) AU666529B2 (de)
CA (1) CA2094424C (de)
DE (1) DE69301750T2 (de)
IL (1) IL105475A (de)
NZ (1) NZ247406A (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040009958A1 (en) * 1991-01-08 2004-01-15 Bone Care International, Inc. Methods for preparation and use of 1alpha,24(S)-dihydroxyvitamin D2
US5661140A (en) * 1994-11-21 1997-08-26 Wisconsin Alumni Research Foundation 18-nor-vitamin D compounds
US5716946A (en) * 1996-02-13 1998-02-10 Wisconsin Alumni Research Foundation Multiple sclerosis treatment
KR100474517B1 (ko) * 1997-10-27 2005-07-21 삼성전자주식회사 엘씨디패널절단장치
US6479474B2 (en) 1999-07-08 2002-11-12 Wisconsin Alumni Research Foundation Dietary calcium as a supplement to vitamin D compound treatment of multiple sclerosis
WO2001022934A2 (en) * 1999-09-24 2001-04-05 Yng Wong Quing Non Delivery of small doses of ingestible treatments
US20060135491A1 (en) * 2004-12-06 2006-06-22 Roger Bouillon Vitamin D3 analog useful for the treatment of osteoporosis
WO2007104407A1 (en) * 2006-03-10 2007-09-20 Dsm Ip Assets B.V. Novel use of a nutraceutical compositions in animal feed
MX339746B (es) 2009-01-27 2016-06-08 Berg Llc Vitamina d3 y análogos de la misma para aliviar efectos secundarios asociados con la quimioterapia.
AU2010282731C1 (en) 2009-08-14 2016-04-21 Berg Llc Vitamin D3 and analogs thereof for treating alopecia
EP3003497B1 (de) 2013-05-29 2024-02-14 BPGbio, Inc. Verhinderung oder verringerung von chemotherapieinduzierter alopezie mit vitamin d

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3833622A (en) * 1969-03-17 1974-09-03 Upjohn Co Crystalline 25-hydroxycholecalciferol hydrate and structurally related compounds
US3901928A (en) * 1973-01-10 1975-08-26 Robert Henry Hesse 1' ,3' -dihydroxy steroid-5-enes method of preparing same and their use for preparing 1' -hydroxy-25-hydrogen vitamin d compounds
US4260549A (en) * 1979-05-21 1981-04-07 Wisconsin Alumni Research Foundation Process for preparing 1α-hydroxylated compounds
US4267117A (en) * 1978-06-19 1981-05-12 The Upjohn Company Compounds and process
US4255596A (en) * 1980-02-25 1981-03-10 Gulf Research & Development Company Preparation of ethylene glycol from ethylene
JPS6089422A (ja) * 1983-10-24 1985-05-20 Kureha Chem Ind Co Ltd 抗骨粗鬆症剤
US4719204A (en) * 1984-03-05 1988-01-12 Wisconsin Alumni Research Foundation Fowl bone mineralization with 28-NOR 1α-hydroxyvitamin D2 analogs
US4588716A (en) * 1984-05-04 1986-05-13 Wisconsin Alumni Research Foundation Method for treating metabolic bone disease in mammals
US4588528A (en) * 1984-05-31 1986-05-13 Wisconsin Alumni Research Foundation 1,24-dihydroxy-Δ22 -vitamin D3 and process for preparing same
US4822609A (en) * 1984-12-21 1989-04-18 The Procter & Gamble Company Treatment of osteoporosis
US4833125A (en) * 1986-12-05 1989-05-23 The General Hospital Corporation Method of increasing bone mass
US5001118A (en) * 1986-12-29 1991-03-19 Kureha Kagaku Kogyo Kabushiki Kaisha Method for preventing senescence and increasing bone mass
US4997824A (en) * 1987-07-22 1991-03-05 Teva Pharmaceutical Industries Ltd. Combination of cholecalciferol derivatives for the treatment of renal bone disease
US5104864A (en) * 1988-08-02 1992-04-14 Bone Care International, Inc. Method for treating and preventing loss of bone mass
US5053401A (en) * 1989-02-28 1991-10-01 Chugai Seiyaku Kabushiki Kaisha Osteogenesis promotion with use of vitamin d derivatives

Also Published As

Publication number Publication date
US5395830A (en) 1995-03-07
NZ247406A (en) 1999-05-28
ATE135220T1 (de) 1996-03-15
EP0567352A1 (de) 1993-10-27
CA2094424A1 (en) 1993-10-25
IL105475A (en) 1997-06-10
CA2094424C (en) 2001-01-02
IL105475A0 (en) 1993-08-18
KR940005275A (ko) 1994-03-21
JP2769960B2 (ja) 1998-06-25
DE69301750D1 (de) 1996-04-18
AU666529B2 (en) 1996-02-15
EP0567352B1 (de) 1996-03-13
JPH0624992A (ja) 1994-02-01
AU3689193A (en) 1993-10-28

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee