DE69304092T2 - Knochenersatzwerkstoff und Verfahren zu seiner Herstellung - Google Patents

Knochenersatzwerkstoff und Verfahren zu seiner Herstellung

Info

Publication number
DE69304092T2
DE69304092T2 DE69304092T DE69304092T DE69304092T2 DE 69304092 T2 DE69304092 T2 DE 69304092T2 DE 69304092 T DE69304092 T DE 69304092T DE 69304092 T DE69304092 T DE 69304092T DE 69304092 T2 DE69304092 T2 DE 69304092T2
Authority
DE
Germany
Prior art keywords
sheet
mixture
animal
bone
manufacture
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69304092T
Other languages
English (en)
Other versions
DE69304092D1 (de
Inventor
Michio Ito
Hiroshi Yagasaki
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
MATSUMOTO DENTAL COLLEGE SHIOJ
Original Assignee
MATSUMOTO DENTAL COLLEGE SHIOJ
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP02410692A external-priority patent/JP3208585B2/ja
Priority claimed from JP02411192A external-priority patent/JP3208586B2/ja
Application filed by MATSUMOTO DENTAL COLLEGE SHIOJ filed Critical MATSUMOTO DENTAL COLLEGE SHIOJ
Publication of DE69304092D1 publication Critical patent/DE69304092D1/de
Application granted granted Critical
Publication of DE69304092T2 publication Critical patent/DE69304092T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K6/00—Preparations for dentistry
    • A61K6/50—Preparations specially adapted for dental root treatment
    • A61K6/54—Filling; Sealing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K6/00—Preparations for dentistry
    • A61K6/80—Preparations for artificial teeth, for filling teeth or for capping teeth
    • A61K6/831—Preparations for artificial teeth, for filling teeth or for capping teeth comprising non-metallic elements or compounds thereof, e.g. carbon
    • A61K6/838—Phosphorus compounds, e.g. apatite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K6/00—Preparations for dentistry
    • A61K6/80—Preparations for artificial teeth, for filling teeth or for capping teeth
    • A61K6/849—Preparations for artificial teeth, for filling teeth or for capping teeth comprising inorganic cements
    • A61K6/876—Calcium oxide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/0005—Ingredients of undetermined constitution or reaction products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
    • A61L24/08—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/20—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
    • A61L27/3608—Bone, e.g. demineralised bone matrix [DBM], bone powder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3641—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the site of application in the body
    • A61L27/3645—Connective tissue
    • A61L27/365—Bones
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
    • C08L5/08—Chitin; Chondroitin sulfate; Hyaluronic acid; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/02—Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants
DE69304092T 1992-02-10 1993-02-09 Knochenersatzwerkstoff und Verfahren zu seiner Herstellung Expired - Fee Related DE69304092T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP02410692A JP3208585B2 (ja) 1992-02-10 1992-02-10 硬化型中性骨形成物の製造方法
JP02411192A JP3208586B2 (ja) 1992-02-10 1992-02-10 シート状骨補填剤の製造方法

Publications (2)

Publication Number Publication Date
DE69304092D1 DE69304092D1 (de) 1996-09-26
DE69304092T2 true DE69304092T2 (de) 1997-01-02

Family

ID=26361594

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69304092T Expired - Fee Related DE69304092T2 (de) 1992-02-10 1993-02-09 Knochenersatzwerkstoff und Verfahren zu seiner Herstellung

Country Status (4)

Country Link
US (1) US6214048B1 (de)
EP (1) EP0555807B1 (de)
AT (1) ATE141493T1 (de)
DE (1) DE69304092T2 (de)

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JP3143660B2 (ja) * 1997-11-27 2001-03-07 工業技術院長 亜鉛含有リン酸三カルシウムからなるセラミックス及び亜鉛徐放性生体用セラミックス
US6030635A (en) * 1998-02-27 2000-02-29 Musculoskeletal Transplant Foundation Malleable paste for filling bone defects
US20030147860A1 (en) 2002-02-07 2003-08-07 Marchosky J. Alexander Compositions and methods for forming and strengthening bone
KR100563476B1 (ko) 1998-07-03 2006-03-27 이진용 골재생재료
DE69810165T2 (de) * 1998-10-19 2003-07-17 Synthes Ag Aushärtbarer keramischer hydraulischer zement
US7086864B2 (en) * 1999-05-12 2006-08-08 Pentron Clinical Technologies, Llc Endodontic post system
US7168952B2 (en) * 1999-05-12 2007-01-30 Pentron Clinical Technologies, Llc Endodontic post and obturating system
US7163401B2 (en) * 1999-05-12 2007-01-16 Pentron Clinical Technologies, Llc Endodontic post and obturating system
JP4472804B2 (ja) * 1999-05-18 2010-06-02 学校法人松本歯科大学 骨補填剤及びその製造方法
CA2377435A1 (en) 1999-06-29 2001-01-04 J. Alexander Marchosky Compositions and methods for forming and strengthening bone
US20030228288A1 (en) 1999-10-15 2003-12-11 Scarborough Nelson L. Volume maintaining osteoinductive/osteoconductive compositions
US9387094B2 (en) 2000-07-19 2016-07-12 Warsaw Orthopedic, Inc. Osteoimplant and method of making same
ES2169681B1 (es) * 2000-08-10 2003-10-01 Osfarma S L Metodo de produccion de filmes de quitosan con una alta capacidad de adherencia celular, producto obrenido y aplicaciones.
US7323193B2 (en) 2001-12-14 2008-01-29 Osteotech, Inc. Method of making demineralized bone particles
EP1416888A4 (de) * 2001-07-16 2007-04-25 Depuy Products Inc Vorrichtung und verfahren zur regeneration des meniskus
US7163563B2 (en) * 2001-07-16 2007-01-16 Depuy Products, Inc. Unitary surgical device and method
EP1416886A4 (de) * 2001-07-16 2007-04-18 Depuy Products Inc Gerüst und verfahren für die knorpelreparatur und regeneration
US7819918B2 (en) * 2001-07-16 2010-10-26 Depuy Products, Inc. Implantable tissue repair device
US7201917B2 (en) * 2001-07-16 2007-04-10 Depuy Products, Inc. Porous delivery scaffold and method
EP1416866A4 (de) * 2001-07-16 2007-04-18 Depuy Products Inc Vorrichtungen aus natürlich vorkommenden mitteln biologischer herkunft
WO2003007790A2 (en) * 2001-07-16 2003-01-30 Depuy Products, Inc. Hybrid biologic/synthetic porous extracellular matrix scaffolds
US8025896B2 (en) * 2001-07-16 2011-09-27 Depuy Products, Inc. Porous extracellular matrix scaffold and method
US7163691B2 (en) 2001-10-12 2007-01-16 Osteotech, Inc. Bone graft
US7750063B2 (en) 2001-10-24 2010-07-06 Pentron Clinical Technologies, Llc Dental filling material
JP2003128704A (ja) 2001-10-24 2003-05-08 Matsumoto Shika Univ キチン・キトサンの低分子化方法及び骨伝導物の製造方法
US7211136B2 (en) * 2001-10-24 2007-05-01 Pentron Clinical Technologies, Llc Dental filling material
US7204875B2 (en) * 2001-10-24 2007-04-17 Pentron Clinical Technologies, Llc Dental filling material
US7204874B2 (en) * 2001-10-24 2007-04-17 Pentron Clinical Technologies, Llc Root canal filling material
US7303817B2 (en) * 2001-10-24 2007-12-04 Weitao Jia Dental filling material
AU2002362220A1 (en) 2001-12-27 2003-07-24 Osteotech Inc. Bone fasteners and method for stabilizing vertebral bone facets using the bone fasteners
NZ544050A (en) 2003-06-11 2009-03-31 Osteotech Inc Osteoimplants and methods for their manufacture
BR122015011568B1 (pt) * 2003-08-08 2017-03-28 Argonne Nat Laboratory misturas para formar um material cerâmico para uso em aplicações dentais e ortopédicas
JP2005087440A (ja) * 2003-09-17 2005-04-07 Matsumoto Shika Univ 海洋生物の原料を含む組成物、及びその組成物の製造方法
US7354627B2 (en) * 2004-12-22 2008-04-08 Depuy Products, Inc. Method for organizing the assembly of collagen fibers and compositions formed therefrom
WO2007056671A1 (en) 2005-11-02 2007-05-18 Osteotech, Inc. Hemostatic bone graft
EP1962713A2 (de) * 2005-11-25 2008-09-03 Lietzau, Markus Verwendung von knochenklebstoff zur abdichtung eines apikalen foramens
US7871440B2 (en) * 2006-12-11 2011-01-18 Depuy Products, Inc. Unitary surgical device and method
JP2012506733A (ja) 2008-10-24 2012-03-22 ウォーソー・オーソペディック・インコーポレーテッド 骨形成を促進するための組成物および方法
US20100268341A1 (en) * 2009-04-16 2010-10-21 WARSAW ORTHOPEDIC, INC., An Indian Corporation Minimally invasive expandable vertebral implant and method
CO6530149A1 (es) * 2011-03-28 2012-09-28 Sur Occidental De Aceites Biocompuesto ceramico para regeneracion osea
US9040093B2 (en) * 2013-03-13 2015-05-26 Orthovita, Inc. Bone graft materials containing calcium phosphate and chitosan
CN103656753B (zh) * 2013-12-04 2015-04-22 上海纳米技术及应用国家工程研究中心有限公司 磷酸钙系中性骨水泥及其制备方法
EP3388092A1 (de) 2017-04-13 2018-10-17 Septodont ou Septodont SAS ou Specialites Septodont Bindegewebe, wie knochen, dentin oder zellstoff, regeneratives material mit kalziumsilikat
PL3609549T3 (pl) 2017-04-13 2022-04-11 Septodont Ou Septodont Sas Ou Specialites Septodont Materiał regeneracyjny tkanek łącznych, przykładowo kości, zębiny lub miazgi, zawierający krzemian wapnia
CN112220964A (zh) * 2020-10-19 2021-01-15 西安点云生物科技有限公司 一种复合生物陶瓷粉及其制备的复合生物陶瓷人工骨和制备方法

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Also Published As

Publication number Publication date
EP0555807A1 (de) 1993-08-18
ATE141493T1 (de) 1996-09-15
DE69304092D1 (de) 1996-09-26
EP0555807B1 (de) 1996-08-21
US6214048B1 (en) 2001-04-10

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Legal Events

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8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee