DE69309468T2 - Nachweis eines Analyten mittels eines Analyt-sensitiven Polymers - Google Patents

Nachweis eines Analyten mittels eines Analyt-sensitiven Polymers

Info

Publication number
DE69309468T2
DE69309468T2 DE69309468T DE69309468T DE69309468T2 DE 69309468 T2 DE69309468 T2 DE 69309468T2 DE 69309468 T DE69309468 T DE 69309468T DE 69309468 T DE69309468 T DE 69309468T DE 69309468 T2 DE69309468 T2 DE 69309468T2
Authority
DE
Germany
Prior art keywords
polymer
analyte
transducing
detection
ter
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69309468T
Other languages
English (en)
Other versions
DE69309468D1 (de
Inventor
Richard Ebersole
Robert Foss
Michael Ward
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
EIDP Inc
Original Assignee
EI Du Pont de Nemours and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by EI Du Pont de Nemours and Co filed Critical EI Du Pont de Nemours and Co
Publication of DE69309468D1 publication Critical patent/DE69309468D1/de
Application granted granted Critical
Publication of DE69309468T2 publication Critical patent/DE69309468T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/04—Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/808—Optical sensing apparatus
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/968—High energy substrates, e.g. fluorescent, chemiluminescent, radioactive
DE69309468T 1992-07-17 1993-07-09 Nachweis eines Analyten mittels eines Analyt-sensitiven Polymers Expired - Fee Related DE69309468T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US91633492A 1992-07-17 1992-07-17
PCT/US1993/006367 WO1994002852A1 (en) 1992-07-17 1993-07-09 Analyte detection by means of an analyte-responsive polymer

Publications (2)

Publication Number Publication Date
DE69309468D1 DE69309468D1 (de) 1997-05-07
DE69309468T2 true DE69309468T2 (de) 1997-09-04

Family

ID=25437095

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69309468T Expired - Fee Related DE69309468T2 (de) 1992-07-17 1993-07-09 Nachweis eines Analyten mittels eines Analyt-sensitiven Polymers

Country Status (7)

Country Link
US (2) US5695925A (de)
EP (1) EP0650598B1 (de)
JP (1) JPH07509264A (de)
AT (1) ATE151174T1 (de)
CA (1) CA2139242A1 (de)
DE (1) DE69309468T2 (de)
WO (1) WO1994002852A1 (de)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6568392B1 (en) * 1995-09-11 2003-05-27 3M Innovative Properties Company Flat-folded personal respiratory protection devices and processes for preparing same
IL114692A (en) * 1995-07-21 1999-10-28 Yissum Res Dev Co Determination of an analyte in a liquid medium
ATE239905T1 (de) * 1996-06-20 2003-05-15 Univ New York Bestimmung von ligand-wechselwirkung mit einem polymermaterial
US5922537A (en) * 1996-11-08 1999-07-13 N.o slashed.AB Immunoassay, Inc. Nanoparticles biosensor
AU7062798A (en) * 1997-04-16 1998-11-11 Mohammed El Hassan Amrani Assessing the composition of liquids
EP1127263A1 (de) * 1998-10-30 2001-08-29 Photonic Sensor Systems Verfahren und sensoren zum nachweis oder zur messung einer säure oder base
US6975944B1 (en) * 1999-09-28 2005-12-13 Alpha Mos Method and apparatus for monitoring materials used in electronics
US20060210440A1 (en) * 1999-11-17 2006-09-21 General Electric Company Opto-acoustic sensor system and associated method
US20030053936A1 (en) * 2001-08-02 2003-03-20 General Electric Company Opto-acoustic wave chemical sensor
US7148017B1 (en) * 2000-07-12 2006-12-12 Cornell Research Foundation, Inc. High sensitivity mechanical resonant sensor
DE60033648T2 (de) * 2000-07-27 2007-11-08 Micronas Holding Gmbh Auf einer Oberfläche befestigte polyfunktionelle Polymernetzwerke für Sensorchips
JP3398366B2 (ja) * 2000-08-09 2003-04-21 富士写真フイルム株式会社 Ｄｎａ分析用マイクロアレイの製造方法
JP2002122420A (ja) * 2000-10-16 2002-04-26 Nippon Mektron Ltd 銅面防錆皮膜の厚み測定方法および装置
DE60033665T2 (de) * 2000-10-31 2007-10-31 Micronas Gmbh Gemusterte Polymeroberflächen geeignet für Biokonjugationen und Verfahren zu ihrer Herstellung
US20060198760A1 (en) * 2001-08-02 2006-09-07 General Electric Company Opto-acoustic sensor device and associated method
CN100498278C (zh) * 2002-05-28 2009-06-10 独立行政法人产业技术综合研究所 通过使用石英振荡器测量痕量物质的方法
GB0215878D0 (en) * 2002-07-09 2002-08-14 Smart Holograms Ltd Cell detection
US20040223884A1 (en) * 2003-05-05 2004-11-11 Ing-Shin Chen Chemical sensor responsive to change in volume of material exposed to target particle
WO2004104567A1 (en) * 2003-05-22 2004-12-02 Elop Electro-Optics Industries Ltd. Quartz crystal microbalance humidity sensor
SE526927C2 (sv) * 2003-11-24 2005-11-22 Hoek Instr Ab Realtidsanalys av gasblandningar
US7274835B2 (en) * 2004-02-18 2007-09-25 Cornell Research Foundation, Inc. Optical waveguide displacement sensor
GB0418123D0 (en) * 2004-08-13 2004-09-15 Asahi Chemical Ind Polymers useful as medical materials
WO2007011404A2 (en) * 2004-10-27 2007-01-25 Eltron Research, Inc Infrared sensors
GB0605302D0 (en) * 2006-03-16 2006-04-26 Akubio Ltd Improvements in or relating to coating surfaces
DE102006020866A1 (de) * 2006-05-04 2007-11-15 Siemens Ag Analyseeinheit, Biosensor und Verfahren für den Nachweis oder die Konzentrationsbestimmung eines Analyten
US20080245135A1 (en) * 2006-11-15 2008-10-09 Cornell Research Foundation, Inc. Microfluidic encapsulated nems resonators
KR101040838B1 (ko) * 2007-10-30 2011-06-14 삼성에스디아이 주식회사 연료전지 시스템 및 이를 위한 유체 센싱 장치
EP2141490B1 (de) * 2008-07-02 2015-04-01 Stichting IMEC Nederland Chemische Messvorrichtung mit Mikroausleger
US20100238035A1 (en) * 2009-03-19 2010-09-23 Tangidyne Corporation Detection device and method for detecting analyte
FR2952786B1 (fr) * 2009-11-17 2012-06-08 Centre Nat Rech Scient Torche a plasma et procede de stabilisation d'une torche a plasma
US20110236877A1 (en) * 2010-03-26 2011-09-29 Da-Jeng Yao Biosensor and method using the same to perform a biotest
CN102344520B (zh) * 2011-07-12 2015-04-22 华东理工大学 两种pH敏感再生型聚合物、其制备方法和形成的再生型两水相体系及应用
US20160138963A1 (en) * 2013-06-17 2016-05-19 Empire Technology Development Llc Graded films
US11275050B2 (en) * 2017-12-05 2022-03-15 Femtodx, Inc. Semiconductor-based biosensor and detection methods

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4312228A (en) * 1979-07-30 1982-01-26 Henry Wohltjen Methods of detection with surface acoustic wave and apparati therefor
US4749762A (en) * 1982-05-12 1988-06-07 E. I. Du Pont De Nemours And Company Acrylic amphoteric polymers
US4735906A (en) * 1984-11-28 1988-04-05 Texas A&M University Sensor having piezoelectric crystal for microgravimetric immunoassays
DE3684166D1 (de) * 1985-04-22 1992-04-16 Du Pont Synthetische amphoterische polymere enthaltender wash-off-film.
US4732930A (en) * 1985-05-20 1988-03-22 Massachusetts Institute Of Technology Reversible, discontinuous volume changes of ionized isopropylacrylamide cells
EP0215669A3 (de) * 1985-09-17 1989-08-30 Seiko Instruments Inc. Vorrichtung und Verfahren zur Analysierung von Biochemikalien, Mikroben und Zellen
GB8618133D0 (en) * 1986-07-24 1986-09-03 Pa Consulting Services Biosensors
JPS63206653A (ja) * 1987-02-24 1988-08-25 Canon Inc 塩温度センサ−
US4916075A (en) * 1987-08-19 1990-04-10 Ohmicron Corporation Differential homogeneous immunosensor device
DE3733986A1 (de) * 1987-10-08 1989-04-20 Mueller Schulte Detlef Dr Mittel und verfahren zur herstellung von biosensoren auf der basis eines schwingquarzes und verwendung desselben zur bestimmung von antigenen und affinitaetsliganden
JP2645884B2 (ja) * 1989-02-13 1997-08-25 三洋電機株式会社 半導体湿度センサ
US5268305A (en) * 1989-06-15 1993-12-07 Biocircuits Corporation Multi-optical detection system
US5156810A (en) * 1989-06-15 1992-10-20 Biocircuits Corporation Biosensors employing electrical, optical and mechanical signals
US5135852A (en) * 1989-07-25 1992-08-04 E. I. Du Pont De Nemours And Company Piezoelectric cell growth biosensing method using polymer-metabolic product complex interactions
EP0494896B1 (de) * 1989-10-04 1994-07-06 E.I. Du Pont De Nemours And Company Bestimmungsverfahren für biologische zielkomplexe auf der oberfläche eines biosensors
US5015843A (en) * 1990-02-15 1991-05-14 Polysense, Inc. Fiber optic chemical sensors based on polymer swelling
US5028394A (en) * 1990-04-13 1991-07-02 Bend Research, Inc. Chemical sensors
US5224972A (en) * 1990-09-11 1993-07-06 Frye Gregory C Coatings with controlled porosity and chemical properties
US5403746A (en) * 1993-11-30 1995-04-04 Minnesota Mining And Manufacturing Company Sensor with improved drift stability

Also Published As

Publication number Publication date
ATE151174T1 (de) 1997-04-15
EP0650598A1 (de) 1995-05-03
DE69309468D1 (de) 1997-05-07
CA2139242A1 (en) 1994-02-03
JPH07509264A (ja) 1995-10-12
WO1994002852A1 (en) 1994-02-03
EP0650598B1 (de) 1997-04-02
US5756279A (en) 1998-05-26
US5695925A (en) 1997-12-09

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee