DE69315079T2 - Beta-aminoalkyl und beta-n-peptidylaminoalkylborsäure - Google Patents

Beta-aminoalkyl und beta-n-peptidylaminoalkylborsäure

Info

Publication number
DE69315079T2
DE69315079T2 DE69315079T DE69315079T DE69315079T2 DE 69315079 T2 DE69315079 T2 DE 69315079T2 DE 69315079 T DE69315079 T DE 69315079T DE 69315079 T DE69315079 T DE 69315079T DE 69315079 T2 DE69315079 T2 DE 69315079T2
Authority
DE
Germany
Prior art keywords
beta
acid
peptidylaminoalkylboric
aminoalkyl
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69315079T
Other languages
English (en)
Other versions
DE69315079D1 (de
Inventor
David Bjorkquist
Rajan Panandiker
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Procter and Gamble Co
Original Assignee
Procter and Gamble Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Procter and Gamble Co filed Critical Procter and Gamble Co
Application granted granted Critical
Publication of DE69315079D1 publication Critical patent/DE69315079D1/de
Publication of DE69315079T2 publication Critical patent/DE69315079T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16—Organic compounds
    • C11D3/38—Products with no well-defined composition, e.g. natural products
    • C11D3/386—Preparations containing enzymes, e.g. protease or amylase
    • C11D3/38663—Stabilised liquid enzyme compositions
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic System
    • C07F5/02—Boron compounds
    • C07F5/025—Boronic and borinic acid compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06191—Dipeptides containing heteroatoms different from O, S, or N
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
DE69315079T 1992-08-14 1993-08-03 Beta-aminoalkyl und beta-n-peptidylaminoalkylborsäure Expired - Fee Related DE69315079T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/931,809 US5442100A (en) 1992-08-14 1992-08-14 β-aminoalkyl and β-N-peptidylaminoalkyl boronic acids
PCT/US1993/007276 WO1994004542A1 (en) 1992-08-14 1993-08-03 β-AMINOALKYL AND β-N-PEPTIDYLAMINOALKYL BORONIC ACIDS

Publications (2)

Publication Number Publication Date
DE69315079D1 DE69315079D1 (de) 1997-12-11
DE69315079T2 true DE69315079T2 (de) 1998-06-04

Family

ID=25461390

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69315079T Expired - Fee Related DE69315079T2 (de) 1992-08-14 1993-08-03 Beta-aminoalkyl und beta-n-peptidylaminoalkylborsäure

Country Status (10)

Country Link
US (2) US5442100A (de)
EP (1) EP0655067B1 (de)
JP (1) JPH08500113A (de)
CN (1) CN1047596C (de)
AT (1) ATE159945T1 (de)
AU (1) AU4799793A (de)
DE (1) DE69315079T2 (de)
MX (1) MX9304970A (de)
TW (1) TW251274B (de)
WO (1) WO1994004542A1 (de)

Families Citing this family (56)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0583536B1 (de) * 1992-08-14 1997-03-05 The Procter & Gamble Company Alpha-aminoborsäurehaltige flüssige Waschmittel
BR9407048A (pt) * 1993-07-09 1996-08-13 Novo Nordisk As Composiçao liquida
US5834415A (en) * 1994-04-26 1998-11-10 Novo Nordisk A/S Naphthalene boronic acids
DE4422433A1 (de) * 1994-06-28 1996-01-04 Cognis Bio Umwelt Mehrenzymgranulat
US5731439A (en) * 1995-03-24 1998-03-24 The Dupont Merck Pharmaceutical Company Piperidine containing aminobornic acids
US6086634A (en) 1995-06-05 2000-07-11 Custom Cleaner, Inc. Dry-cleaning compositions containing polysulfonic acid
AU5950696A (en) 1995-06-05 1996-12-24 Creative Products Resource, Inc. Dry-cleaning kit for in-dryer use
US6036727A (en) 1995-06-05 2000-03-14 Creative Products Resource, Inc. Anhydrous dry-cleaning compositions containing polysulfonic acid, and dry-cleaning kits for delicate fabrics
US5658651A (en) 1995-09-29 1997-08-19 Creative Products Resource, Inc. Fabric treatment and softener system for in-dryer use
ATE217342T1 (de) * 1995-06-13 2002-05-15 Novozymes As 4-substituierte-phenylboronsäuren als enzymstabilisatoren
MXPA01013006A (es) * 1999-06-14 2002-07-30 Wisconsin Alumni Res Found Oligomeros y polimeros de acidos imino-carboxilicos ciclicos.
US20060063690A1 (en) * 2004-09-08 2006-03-23 Billiauw Jan Julien M Laundry treatment compositions with improved odor
EP2242831B2 (de) 2008-01-04 2023-05-17 The Procter & Gamble Company Waschmittelzusammensetzung mit glycosylhydrolase
US20090209447A1 (en) 2008-02-15 2009-08-20 Michelle Meek Cleaning compositions
BRPI0913570A2 (pt) 2008-06-06 2015-12-15 Procter & Gamble composição detergente compreendendo uma variante de uma xiloglucanase da família 44
EA027346B1 (ru) * 2008-06-17 2017-07-31 Милленниум Фармасьютикалз, Инк. Соединения боронатного эфира и его фармацевтические составы
JP2012532246A (ja) 2009-07-09 2012-12-13 ザ プロクター アンド ギャンブル カンパニー 比較的低濃度の水溶性電解質を含む触媒性洗濯洗剤組成物
BR112012000520A2 (pt) 2009-07-09 2016-02-16 Procter & Gamble composição catalítica detergente para lavagem de roupa que compreende teores relativamente baixos de eletrólito solúvel em água
US8933131B2 (en) 2010-01-12 2015-01-13 The Procter & Gamble Company Intermediates and surfactants useful in household cleaning and personal care compositions, and methods of making the same
EP2365053B1 (de) 2010-03-12 2016-04-27 The Procter & Gamble Company Flüssige Waschmittelzusammensetzungen mit pH-einstellbaren Amido-Dickungsmitteln und Herstellungsverfahren
EP2365050B1 (de) 2010-03-12 2016-08-10 The Procter and Gamble Company Di-amido-dickungsmittel zur verwendung in verbraucherproduktzusammensetzungen
KR101987091B1 (ko) 2010-08-10 2019-06-10 렘펙스 파머수티클스 인코퍼레이티드 고리형 보론산 에스터 유도체 및 이의 치료상 용도
US20120213726A1 (en) 2011-02-17 2012-08-23 Phillip Richard Green Bio-based linear alkylphenyl sulfonates
JP5815750B2 (ja) 2011-02-17 2015-11-17 ザ プロクター アンド ギャンブルカンパニー Ｃ１０〜ｃ１３アルキルフェニルスルホネートの混合物を含む組成物
US8921299B2 (en) 2011-07-25 2014-12-30 The Procter & Gamble Company Detergents having acceptable color
US20130303427A1 (en) 2011-09-13 2013-11-14 Susana Fernandez Prieto MICROCAPSULE COMPOSITIONS COMPRISING pH TUNEABLE DI-AMIDO GELLANTS
EP2802593A1 (de) * 2012-01-09 2014-11-19 The University of Tromsoe Therapeutische boronhaltige verbindungen
EP2716644B1 (de) 2012-10-03 2017-04-05 The Procter and Gamble Company Stabile Enzymstabilisatorvormischung
BR112015016001A2 (pt) 2013-01-04 2017-07-11 Rempex Pharmaceuticals Inc compostos, composições farmacêuticas e respectivos usos e método para tratar ou prevenir infecção bacteriana
US9241947B2 (en) 2013-01-04 2016-01-26 Rempex Pharmaceuticals, Inc. Boronic acid derivatives and therapeutic uses thereof
WO2014152674A1 (en) 2013-03-14 2014-09-25 Novozymes A/S Enzyme and inhibitor containing water-soluble films
CN105164244B (zh) 2013-05-03 2019-08-20 诺维信公司 洗涤剂酶的微囊化
WO2015171430A1 (en) 2014-05-05 2015-11-12 Rempex Pharmaceuticals, Inc. Synthesis of boronate salts and uses thereof
WO2015171398A1 (en) 2014-05-05 2015-11-12 Rempex Pharmaceuticals, Inc. Salts and polymorphs of cyclic boronic acid ester derivatives and therapeutic uses thereof
EA201691988A1 (ru) 2014-05-19 2017-06-30 Ремпекс Фармасьютикалз, Инк. Производные бороновой кислоты и их терапевтическое применение
UY36132A (es) 2014-05-20 2015-11-30 Millennium Pharm Inc Métodos para terapia de cáncer
MX2016016666A (es) 2014-07-01 2017-08-08 Rempex Pharmaceuticals Inc Derivados de acido boronico y usos terapeuticos de los mismos.
US20170121646A1 (en) 2014-07-03 2017-05-04 Novozymes A/S Improved Stabilization of Non-Protease Enzyme
US10662205B2 (en) 2014-11-18 2020-05-26 Qpex Biopharma, Inc. Cyclic boronic acid ester derivatives and therapeutic uses thereof
CN107109388A (zh) 2014-12-19 2017-08-29 诺维信公司 蛋白酶变体以及对其进行编码的多核苷酸
ES2761778T3 (es) 2014-12-19 2020-05-21 Rempex Pharmaceuticals Inc Aparato y proceso de flujo continuo para la producción de derivados de ácido borónico
US20180051041A1 (en) 2015-03-17 2018-02-22 Rempex Pharmaceuticals, Inc. Boronic acid derivatives and therapeutic uses thereof
CN114292829A (zh) 2015-07-06 2022-04-08 诺维信公司 脂肪酶变体以及编码它们的多核苷酸
BR112018007474A2 (pt) 2015-10-14 2018-10-30 Novozymes A/S ?limpeza de membranas de filtração de água?
DK3478693T3 (da) 2016-06-30 2021-09-20 Qpex Biopharma Inc Boronsyrederivater og terapeutiske anvendelser deraf
US11078445B2 (en) 2017-05-05 2021-08-03 Novozymes A/S Compositions comprising lipase and sulfite
CN111108183A (zh) 2017-06-30 2020-05-05 诺维信公司 酶浆液组合物
MX2020003495A (es) 2017-10-11 2020-09-18 Qpex Biopharma Inc Derivados de acido boronico y sintesis de los mismos.
CN111479919A (zh) 2017-11-01 2020-07-31 诺维信公司 多肽以及包含此类多肽的组合物
CN111527190A (zh) 2017-11-01 2020-08-11 诺维信公司 多肽以及包含此类多肽的组合物
CN111770788B (zh) 2018-03-13 2023-07-25 诺维信公司 使用氨基糖低聚物进行微囊化
EP3647397A1 (de) 2018-10-31 2020-05-06 Henkel AG & Co. KGaA Reinigungsmittel mit dispersins iv
EP3647398A1 (de) 2018-10-31 2020-05-06 Henkel AG & Co. KGaA Reinigungszusammensetzungen mit dispersinen v
EP4065677A1 (de) 2019-11-27 2022-10-05 The Procter & Gamble Company Verbesserte alkylbenzolsulfonat-tenside
WO2021123307A2 (en) 2019-12-20 2021-06-24 Novozymes A/S Polypeptides having proteolytic activity and use thereof
EP4305146A1 (de) 2021-03-12 2024-01-17 Novozymes A/S Polypeptidvarianten

Family Cites Families (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2872479A (en) * 1955-06-30 1959-02-03 Callery Chemical Co Preparation of organoboron compounds
US3912595A (en) * 1974-02-25 1975-10-14 Us Health Method of purifying enzymes using boronic acids covalently bonded to an insoluble support
IT1129814B (it) * 1980-07-02 1986-06-11 Unilever Nv Composizione detergente enzimatica liquida
US4462922A (en) * 1981-11-19 1984-07-31 Lever Brothers Company Enzymatic liquid detergent composition
GB8311314D0 (en) * 1983-04-26 1983-06-02 Unilever Plc Aqueous enzyme-containing compositions
US4652394A (en) * 1983-05-31 1987-03-24 Colgate Palmolive Co. Built single phase liquid anionic detergent compositions containing stabilized enzymes
DE3413571A1 (de) * 1984-04-11 1985-10-24 Hoechst Ag, 6230 Frankfurt Verwendung von kristallinen schichtfoermigen natriumsilikaten zur wasserenthaertung und verfahren zur wasserenthaertung
US4537707A (en) * 1984-05-14 1985-08-27 The Procter & Gamble Company Liquid detergents containing boric acid and formate to stabilize enzymes
US4566985A (en) * 1984-09-19 1986-01-28 Applied Biochemists, Inc. Method of cleaning using liquid compositions comprising stabilized mixtures of enzymes
US4747977A (en) * 1984-11-09 1988-05-31 The Procter & Gamble Company Ethanol-free liquid laundry detergent compositions
US4900475A (en) * 1985-07-26 1990-02-13 Colgate-Palmolive Co. Stabilized built liquid detergent composition containing enzyme
US4842769A (en) * 1985-07-26 1989-06-27 Colgate-Palmolive Co. Stabilized fabric softening built detergent composition containing enzymes
WO1987000859A1 (en) * 1985-08-09 1987-02-12 Gist-Brocades N.V. Novel lipolytic enzymes and their use in detergent compositions
EG18543A (en) * 1986-02-20 1993-07-30 Albright & Wilson Protected enzyme systems
US4842758A (en) * 1986-10-31 1989-06-27 Colgate-Palmolive Company Stabilized enzyme system for use in aqueous liquid built detergent compositions
US4704233A (en) * 1986-11-10 1987-11-03 The Procter & Gamble Company Detergent compositions containing ethylenediamine-N,N'-disuccinic acid
US5187157A (en) * 1987-06-05 1993-02-16 Du Pont Merck Pharmaceutical Company Peptide boronic acid inhibitors of trypsin-like proteases
DK571587D0 (da) * 1987-11-02 1987-11-02 Novo Industri As Enzymatisk detergentsammensaetning
EP0315574A3 (de) * 1987-11-05 1990-08-22 Hoechst Aktiengesellschaft Renin-Inhibitoren
GB8810822D0 (en) * 1988-05-06 1988-06-08 Unilever Plc Liquid detergent compositions
US4963655A (en) * 1988-05-27 1990-10-16 Mayo Foundation For Medical Education And Research Boron analogs of amino acid/peptide protease inhibitors
US5039446A (en) * 1988-07-01 1991-08-13 Genencor International, Inc. Liquid detergent with stabilized enzyme
DE3840452A1 (de) * 1988-12-01 1990-06-07 Hoechst Ag (beta)-amino-boronsaeure-derivate
AU4724989A (en) * 1988-12-30 1990-07-05 Unilever Plc Enzymatic liquid detergent composition
US4959179A (en) * 1989-01-30 1990-09-25 Lever Brothers Company Stabilized enzymes liquid detergent composition containing lipase and protease
US4908150A (en) * 1989-02-02 1990-03-13 Lever Brothers Company Stabilized lipolytic enzyme-containing liquid detergent composition
JPH0343073A (ja) * 1989-02-27 1991-02-25 Occidental Chem Corp 種々の温度で活性を有する特異な微生物リパーゼ及び該リパーゼを含有する洗剤
ES2141080T3 (es) * 1989-05-15 2000-03-16 Clorox Co Procedimiento para el lavado de tejidos.
EP0450702A3 (en) * 1990-04-06 1993-06-02 Unilever N.V. Process for preparing liquid enzymatic detergent compositions
EP0478050A1 (de) * 1990-09-24 1992-04-01 Unilever N.V. Detergentzusammensetzung
DK0486073T3 (da) * 1990-11-14 1996-12-09 Procter & Gamble Væskeformig detergentsammensætning, der indeholder lipase og protease

Also Published As

Publication number Publication date
US5442100A (en) 1995-08-15
ATE159945T1 (de) 1997-11-15
TW251274B (de) 1995-07-11
DE69315079D1 (de) 1997-12-11
AU4799793A (en) 1994-03-15
CN1090850A (zh) 1994-08-17
JPH08500113A (ja) 1996-01-09
US5488157A (en) 1996-01-30
CN1047596C (zh) 1999-12-22
EP0655067B1 (de) 1997-11-05
MX9304970A (es) 1994-05-31
EP0655067A1 (de) 1995-05-31
WO1994004542A1 (en) 1994-03-03

Similar Documents

Publication Publication Date Title
DE69315079D1 (de) Beta-aminoalkyl und beta-n-peptidylaminoalkylborsäure
YU34896A (sh) Supstituisani n-(indol-2-karbonil)-glicinamidi, njihovi intermedijeri i farmaceutske kompozicije
AU617875B2 (en) Novel peptidase inhibitors
NO934423L (no) Preparater for vedvarende frigiving
MY137301A (en) Peptide analogs as irreversible interleukin-1b protease inhibitors
NZ296479A (en) Amino acid or peptide derivatives which are inhibitors of multicatalytic protease (mcp)
NZ335157A (en) N-(aryl/heteroaryl) amino acid derivatives and methods for inhibiting beta-amyloid peptide release or its synthesis
NO942740D0 (no) Pyridinkarboksimidamid-forbindelse og anvendelse av samme
DK0868429T3 (da) Oligopeptidforbindelser indeholdende D-2-alkyltryptophan hvilke er i stand til at fremme frigivelsen af væksthormon
UA26459C2 (uk) Іhгібітор впливу амілоїдhих білків
FI930166A0 (fi) Nya salter av dialkylaminoalkyl-26-sulfonylpristinamycin iib-derivat
ATE46347T1 (de) Immunostimulierende peptide.
DK1041082T3 (da) Fremgangsmåde til peptidsyntese ud fra N-carboxyandridaminosyrer
ATE112281T1 (de) Verfahren zur herstellung von streptograminderivaten.
ES2004804A6 (es) Un procedimiento para preparar derivados de carboxialquildipeptidos
TH14443A (th) (สูตร) - อะมิโนแอลคิลและ (สูตร)-n- เพปทิดิลอะมิโนแอลคิลปอโรนิคแอซิด

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee