DE69316620T2 - Verbesserung für optische analyse - Google Patents

Verbesserung für optische analyse

Info

Publication number
DE69316620T2
DE69316620T2 DE69316620T DE69316620T DE69316620T2 DE 69316620 T2 DE69316620 T2 DE 69316620T2 DE 69316620 T DE69316620 T DE 69316620T DE 69316620 T DE69316620 T DE 69316620T DE 69316620 T2 DE69316620 T2 DE 69316620T2
Authority
DE
Germany
Prior art keywords
refractive index
pct
analyte
wavelength
variation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69316620T
Other languages
English (en)
Other versions
DE69316620D1 (de
Inventor
Anders Hanning
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biacore AB
Original Assignee
Biacore AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biacore AB filed Critical Biacore AB
Publication of DE69316620D1 publication Critical patent/DE69316620D1/de
Application granted granted Critical
Publication of DE69316620T2 publication Critical patent/DE69316620T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/41—Refractivity; Phase-affecting properties, e.g. optical path length
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/55—Specular reflectivity
    • G01N21/552—Attenuated total reflection
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/55—Specular reflectivity
    • G01N21/552—Attenuated total reflection
    • G01N21/553—Attenuated total reflection and using surface plasmons
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/551—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being inorganic
    • G01N33/552—Glass or silica
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N21/7703—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator using reagent-clad optical fibres or optical waveguides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/808—Optical sensing apparatus
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/805—Optical property
DE69316620T 1992-06-29 1993-06-29 Verbesserung für optische analyse Expired - Fee Related DE69316620T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9201984A SE9201984D0 (sv) 1992-06-29 1992-06-29 Improvement in optical assays
PCT/SE1993/000589 WO1994000751A1 (en) 1992-06-29 1993-06-29 Improvement in optical assays

Publications (2)

Publication Number Publication Date
DE69316620D1 DE69316620D1 (de) 1998-02-26
DE69316620T2 true DE69316620T2 (de) 1998-07-23

Family

ID=20386627

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69316620T Expired - Fee Related DE69316620T2 (de) 1992-06-29 1993-06-29 Verbesserung für optische analyse

Country Status (8)

Country Link
US (1) US5641640A (de)
EP (1) EP0648328B1 (de)
JP (1) JPH07508346A (de)
AT (1) ATE162627T1 (de)
AU (1) AU4520093A (de)
DE (1) DE69316620T2 (de)
SE (1) SE9201984D0 (de)
WO (1) WO1994000751A1 (de)

Families Citing this family (120)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6521185B1 (en) * 1995-10-23 2003-02-18 American Research Corporation Of Virginia Fluorescent probes based on the affinity of a polymer matrix for an analyte of interest
GB9602542D0 (en) * 1996-02-08 1996-04-10 Fisons Plc Analytical device
US6232124B1 (en) 1996-05-06 2001-05-15 Verification Technologies, Inc. Automated fingerprint methods and chemistry for product authentication and monitoring
EP0901630B1 (de) * 1996-05-23 2003-08-20 Inverness Medical Switzerland GmbH Verbesserungen in oder in bezug auf spezifische bindungsassays
SE9602788L (sv) * 1996-07-16 1998-01-17 Anders Hanning Förbättrad refraktometrisk metod
US6165798A (en) * 1996-10-10 2000-12-26 University Of British Columbia Optical quantification of analytes in membranes
ATE225858T1 (de) 1997-07-28 2002-10-15 Medical Biosystems Ltd Sequenzanalyse von nukleinsäuren
DE19741335C1 (de) * 1997-09-19 1999-06-10 Bosch Gmbh Robert Sensormembran einer Optode sowie Verfahren, Vorrichtung und deren Verwendung zur Bestimmung von Gasen in Gasgemischen
US6346376B1 (en) * 1998-06-03 2002-02-12 Centre Suisse D'electronique Et De Mictotechnique Sa Optical sensor unit and procedure for the ultrasensitive detection of chemical or biochemical analytes
US6432364B1 (en) * 1998-07-06 2002-08-13 Suzuki Motor Corporation SPR sensor cell and immunoassay apparatus using the same
WO2000029830A1 (en) 1998-11-13 2000-05-25 Leica Microsystems, Inc. Refractometer and method for qualitative and quantitative measurements
US6490030B1 (en) 1999-01-18 2002-12-03 Verification Technologies, Inc. Portable product authentication device
US6771376B2 (en) * 1999-07-05 2004-08-03 Novartis Ag Sensor platform, apparatus incorporating the platform, and process using the platform
AU5824300A (en) 1999-07-05 2001-01-22 Novartis Ag Sensor platform, apparatus incorporating the platform, and process using the platform
US6512580B1 (en) 1999-10-27 2003-01-28 Verification Technologies, Inc. Method and apparatus for portable product authentication
US7167615B1 (en) 1999-11-05 2007-01-23 Board Of Regents, The University Of Texas System Resonant waveguide-grating filters and sensors and methods for making and using same
US20040000787A1 (en) * 2000-04-24 2004-01-01 Rakesh Vig Authentication mark for a product or product package
US6638593B2 (en) 2000-06-30 2003-10-28 Verification Technologies, Inc. Copy-protected optical media and method of manufacture thereof
WO2002002301A1 (en) 2000-06-30 2002-01-10 Verification Technologies Inc. Copy-protected optical media and method of manufacture thereof
US7126688B2 (en) * 2000-07-11 2006-10-24 Maven Technologies, Llc Microarray scanning
US7193711B2 (en) * 2000-07-11 2007-03-20 Maven Technologies, Llc Imaging method and apparatus
US6833920B2 (en) 2000-07-11 2004-12-21 Maven Technologies Llc Apparatus and method for imaging
US7023547B2 (en) 2000-07-11 2006-04-04 Maven Technologies, Llc Apparatus including a biochip for imaging of biological samples and method
US7518724B2 (en) * 2000-07-11 2009-04-14 Maven Technologies Image acquisition, processing, and display
US6594011B1 (en) 2000-07-11 2003-07-15 Maven Technologies, Llc Imaging apparatus and method
US7660415B2 (en) 2000-08-03 2010-02-09 Selinfreund Richard H Method and apparatus for controlling access to storage media
US6576430B1 (en) * 2000-11-20 2003-06-10 Becton, Dickinson And Company Detection of ligands by refractive surface methods
JP4173628B2 (ja) * 2000-12-14 2008-10-29 富士フイルム株式会社 表面プラズモン共鳴測定装置
US7208322B2 (en) * 2001-04-02 2007-04-24 Agilent Technologies, Inc. Sensor surfaces for detecting analytes
AU2002258702A1 (en) * 2001-04-02 2002-10-15 Prolinx Incorporated Systems and apparatus for the analysis of molecular interactions
US6858148B2 (en) * 2003-07-16 2005-02-22 The Regents Of The University Of California Method and apparatus for detecting chemical binding
US20040023413A1 (en) * 2001-11-26 2004-02-05 Molecular Reflections, Inc. Microscale immobilization of molecules using a hydrogel and methods of use thereof
US6790632B2 (en) 2002-06-17 2004-09-14 Stephen Eliot Zweig Membrane receptor reagent and assay
US7288368B2 (en) * 2002-06-17 2007-10-30 Stephen Eliot Zweig Membrane receptor reagent and assay
USRE47770E1 (en) 2002-07-18 2019-12-17 Merus N.V. Recombinant production of mixtures of antibodies
ES2368733T3 (es) * 2002-07-18 2011-11-21 Merus B.V. Producción recombinante de mezclas de anticuerpos.
US7015471B2 (en) * 2002-09-25 2006-03-21 North Carolina State University Surface plasmon resonance systems and methods having a variable charge density layer
US20100069614A1 (en) 2008-06-27 2010-03-18 Merus B.V. Antibody producing non-human mammals
CA2527694C (en) 2003-05-30 2015-07-14 Hendricus Renerus Jacobus Mattheus Hoogenboom Fab library for the preparation of anti vegf and anti rabies virus fabs
US7395103B2 (en) * 2004-01-08 2008-07-01 Osmopen, Llc Surface plasmon resonance based nanoliter tear osmometer
EP1737971B1 (de) * 2004-01-20 2017-08-16 Merus N.V. Gemische bindender proteine
US7470549B2 (en) * 2004-05-26 2008-12-30 Fujifilm Corporation Measurement method using biosensor
DE102004033869B3 (de) * 2004-07-13 2006-03-30 Gesellschaft zur Förderung der Spektrochemie und angewandten Spektroskopie e.V. Verfahren zur Bestimmung von Oberflächenplasmonenresonanzen an zweidimensionalen Messflächen
US8249682B2 (en) * 2005-01-07 2012-08-21 Lacrisciences, Llc Device for measuring concentrations of constituents of tear sample
US7749445B2 (en) * 2005-05-02 2010-07-06 Bioscale, Inc. Method and apparatus for analyzing bioprocess fluids
US7300631B2 (en) 2005-05-02 2007-11-27 Bioscale, Inc. Method and apparatus for detection of analyte using a flexural plate wave device and magnetic particles
US7611908B2 (en) * 2005-05-02 2009-11-03 Bioscale, Inc. Method and apparatus for therapeutic drug monitoring using an acoustic device
US7648844B2 (en) * 2005-05-02 2010-01-19 Bioscale, Inc. Method and apparatus for detection of analyte using an acoustic device
CN102441163A (zh) 2005-05-27 2012-05-09 比奥根艾迪克Ma公司 结合tweak的抗体
US20070003559A1 (en) * 2005-07-01 2007-01-04 Wyeth Methods of determining pharmacokinetics of targeted therapies
NZ565511A (en) 2005-07-22 2011-03-31 Five Prime Therapeutics Inc Compositions and methods of treating disease with FGFR fusion proteins
US20090291437A1 (en) * 2005-11-02 2009-11-26 O'brien Sean Methods for targeting quadruplex sequences
US20070161089A1 (en) * 2005-11-08 2007-07-12 Genentech, Inc. Method of Producing Pan-Specific Antibodies
US7889347B2 (en) * 2005-11-21 2011-02-15 Plexera Llc Surface plasmon resonance spectrometer with an actuator driven angle scanning mechanism
US7751052B2 (en) * 2006-12-04 2010-07-06 Electronics And Telecommunications Research Institute Surface plasmon resonance sensor capable of performing absolute calibration
US7867783B2 (en) 2007-02-22 2011-01-11 Maven Technologies, Llc Apparatus and method for performing ligand binding assays on microarrays in multiwell plates
GB2447696A (en) 2007-03-23 2008-09-24 Univ Exeter Photonic biosensor arrays
US7863037B1 (en) 2007-04-04 2011-01-04 Maven Technologies, Llc Ligand binding assays on microarrays in closed multiwell plates
US20090041633A1 (en) * 2007-05-14 2009-02-12 Dultz Shane C Apparatus and method for performing ligand binding assays on microarrays in multiwell plates
US7799558B1 (en) 2007-05-22 2010-09-21 Dultz Shane C Ligand binding assays on microarrays in closed multiwell plates
US8097422B2 (en) 2007-06-20 2012-01-17 Salk Institute For Biological Studies Kir channel modulators
US8354280B2 (en) * 2007-09-06 2013-01-15 Bioscale, Inc. Reusable detection surfaces and methods of using same
CN101836102B (zh) * 2007-10-25 2012-02-29 皇家飞利浦电子股份有限公司 用于样品中靶粒子的传感器装置
US20110188043A1 (en) * 2007-12-26 2011-08-04 Yissum, Research Development Company of The Hebrew University of Jerusalem, Ltd. Method and apparatus for monitoring processes in living cells
US20090227043A1 (en) * 2008-02-19 2009-09-10 Wei Huang Fluorescence Resonance Energy Transfer Assay Based on Modified Solid Surface
US9873957B2 (en) * 2008-03-13 2018-01-23 Dyax Corp. Libraries of genetic packages comprising novel HC CDR3 designs
EP2281078B1 (de) 2008-04-24 2014-10-22 Dyax Corporation Bibliotheken von genetischen packungen, umfassend neue hc-cdr1, -cdr2, und -cdr3, und neue lc-cdr1-, -cdr2- und -cdr3-designs
CA2722082C (en) 2008-04-25 2021-11-09 Christopher Tenhoor Fc receptor binding proteins
US7981664B1 (en) 2008-05-22 2011-07-19 Maven Technologies, Llc Apparatus and method for performing ligand binding assays on microarrays in multiwell plates
US8039270B2 (en) * 2008-05-22 2011-10-18 Maven Technologies, Llc Apparatus and method for performing ligand binding assays on microarrays in multiwell plates
US9682372B2 (en) 2008-06-19 2017-06-20 Carterra, Inc. Tip overlay for continuous flow spotting apparatus
WO2010006201A2 (en) * 2008-07-10 2010-01-14 Abaxis, Inc. Methods of reducing non-specific interaction in metal nanoparticle assays
US20100143349A1 (en) * 2008-08-12 2010-06-10 Wyeth Humanized anti-rage antibody
CA2740440A1 (en) 2008-10-14 2010-04-22 Dyax Corp. Use of igf-ii/igf-iie binding proteins for the treatment and prevention of systemic sclerosis-associated pulmonary fibrosis
KR20100072528A (ko) * 2008-12-22 2010-07-01 한국전자통신연구원 바이오 칩 및 바이오 물질 검출 장치
JP2013504602A (ja) 2009-09-14 2013-02-07 ダイアックス コーポレーション 新しく設計したｈｃｃｄｒ３を含む遺伝子パッケージライブラリー
US8355133B2 (en) * 2009-12-30 2013-01-15 Maven Technologies, Llc Biological testing with sawtooth-shaped prisms
SI2521568T1 (sl) 2010-01-06 2019-01-31 Dyax Corp. Proteini, ki vežejo plazemski kalikrein
CN103097875B (zh) * 2010-05-27 2015-11-25 艾皮森泰克公司 改进的传感器测量方法
WO2012007880A2 (en) 2010-07-16 2012-01-19 Ablynx Nv Modified single domain antigen binding molecules and uses thereof
WO2012141605A1 (en) 2011-02-16 2012-10-18 Centrul International De Biodinamica Systems and method for detection and quantitation of analytes using impedance analysis
EP2714084B1 (de) 2011-06-02 2019-05-22 Dyax Corp. Fc-REZEPTOR-BINDENDE PROTEINE
US20140350868A1 (en) 2011-11-22 2014-11-27 Episentec Ab Method for sensor calibration
NZ700025A (en) * 2012-02-15 2018-07-27 Biocon Ltd A process for detection and optional quantification of an analyte
MX360109B (es) 2012-04-20 2018-10-23 Merus Nv Metodos y medios para la produccion de moleculas de tipo ig.
US10300450B2 (en) 2012-09-14 2019-05-28 Carterra, Inc. Method and device for depositing a substance on a submerged surface
ES2780398T3 (es) 2012-12-10 2020-08-25 Biogen Ma Inc Anticuerpo anti-antígeno 2 de células dendríticas sanguíneas y uso de los mismos
WO2014144466A1 (en) 2013-03-15 2014-09-18 Biogen Idec Ma Inc. Anti-alpha v beta 6 antibodies and uses thereof
WO2014143739A2 (en) 2013-03-15 2014-09-18 Biogen Idec Ma Inc. Anti-alpha v beta 6 antibodies and uses thereof
CA2903546A1 (en) 2013-03-15 2014-09-25 Biogen Ma Inc. Treatment and prevention of acute kidney injury using anti-alpha v beta 5 antibodies
WO2015028571A1 (en) 2013-08-29 2015-03-05 Episentec Ab Improved method of sensor measurement
EP2863332A1 (de) 2013-10-15 2015-04-22 One Drop Diagnostics Sàrl System und Verfahren zur Steuerung des Zugriffs auf analytische Ergebnisse eines diagnostischen Test-Assays
WO2015057939A1 (en) 2013-10-18 2015-04-23 Biogen Idec Ma Inc. Anti-s1p4 antibodies and uses thereof
JP6540710B2 (ja) 2013-11-19 2019-07-10 ジーイー・ヘルスケア・バイオサイエンス・アクチボラグ 速い解離速度の相互作用カイネティクスの決定方法
WO2015090908A1 (en) 2013-12-19 2015-06-25 Ge Healthcare Bio-Sciences Ab Laminated microfluidic device with membrane valves
US9682396B2 (en) 2014-03-24 2017-06-20 Carterra, Inc. Dual flow cell fluid delivery systems
JP6662525B2 (ja) 2014-06-24 2020-03-11 ジーイー・ヘルスケア・バイオサイエンス・アクチボラグ 光学センサ表面における物質移動特性の正規化
WO2016066591A1 (en) 2014-10-30 2016-05-06 Ge Healthcare Bio-Sciences Ab Method to determine solvent correction curves
EP4310503A3 (de) 2015-12-30 2024-03-20 Momenta Pharmaceuticals, Inc. Verfahren im zusammenhang mit biologika
WO2017189483A1 (en) 2016-04-25 2017-11-02 The Johns Hopkins University Znt8 assays for drug development and pharmaceutical compositions
CN106199803B (zh) * 2016-07-25 2018-11-06 镇江爱豪科思电子科技有限公司 一种温度探测用宽带红外滤光片及其制备方法
US20190330318A1 (en) 2016-07-25 2019-10-31 Biogen Ma Inc. Anti-hspa5 (grp78) antibodies and uses thereof
US11072639B2 (en) 2016-09-08 2021-07-27 Regenerative Research Foundation Bi-functional anti-tau polypeptides and use thereof
US20200095301A1 (en) 2016-12-14 2020-03-26 The Board Of Trustees Of The Leland Stanford Junior University Il-13 superkine: immune cell targeting constructs and methods of use thereof
TWI659750B (zh) 2017-01-13 2019-05-21 中央研究院 用以治療心肌梗塞之可重複裝載之改良水膠系統
WO2018130661A1 (en) 2017-01-13 2018-07-19 Academia Sinica Reloadable hydrogel system for treating brain conditions
US11892457B2 (en) 2017-07-12 2024-02-06 The Johns Hopkins University Proteoliposome-based ZnT8 self-antigen for type 1 diabetes diagnosis
EP3802579A1 (de) 2018-06-01 2021-04-14 The Board of Trustees of the Leland Stanford Junior University Il-13/il-4-superkine: gegen immunzellen gerichtete konstrukte und verwendungsverfahren dafür
CN113166241A (zh) 2018-08-16 2021-07-23 约翰霍普金斯大学 人类znt8抗体
US11474109B2 (en) 2018-11-16 2022-10-18 Scintimetrics, Inc. Compositions and methods for controllably merging emulsion droplets and sample analysis
MX2021012160A (es) 2019-04-08 2022-01-06 Biogen Ma Inc Anticuerpos antiintegrina y usos de los mismos.
WO2021217024A1 (en) 2020-04-24 2021-10-28 Millennium Pharmaceuticals, Inc. Anti-cd19 antibodies and uses thereof
CN116615443A (zh) 2020-09-14 2023-08-18 Vor生物制药股份有限公司 针对cd33的单结构域抗体
TW202241946A (zh) 2020-12-18 2022-11-01 美商健生生物科技公司 針對整合素α１１β１之抗體
CN117425673A (zh) 2021-04-09 2024-01-19 武田药品工业株式会社 靶向补体因子d的抗体和其用途
KR20240004286A (ko) 2021-04-26 2024-01-11 밀레니엄 파머슈티컬스 인코퍼레이티드 항 Clec12A 항체 및 이의 용도
EP4330283A1 (de) 2021-04-26 2024-03-06 Millennium Pharmaceuticals, Inc. Anti-adgre2-antikörper und verwendungen davon
GB202107754D0 (en) 2021-05-31 2021-07-14 Univ Newcastle Screening for the effects of complement protein changes
AU2022372894A1 (en) 2021-10-20 2024-04-18 Takeda Pharmaceutical Company Limited Compositions targeting bcma and methods of use thereof
WO2023201238A1 (en) 2022-04-11 2023-10-19 Vor Biopharma Inc. Binding agents and methods of use thereof

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4954435A (en) * 1987-01-12 1990-09-04 Becton, Dickinson And Company Indirect colorimetric detection of an analyte in a sample using ratio of light signals
IL85137A (en) * 1987-01-21 1992-02-16 Ares Serono Res & Dev Ltd Method of assaying for a ligand using surface plasmon resonance effect
GB8801807D0 (en) * 1988-01-27 1988-02-24 Amersham Int Plc Biological sensors
EP0341927B1 (de) * 1988-05-10 1993-07-14 AMERSHAM INTERNATIONAL plc Biosensoren
SE462408B (sv) * 1988-11-10 1990-06-18 Pharmacia Ab Optiskt biosensorsystem utnyttjande ytplasmonresonans foer detektering av en specific biomolekyl, saett att kalibrera sensoranordningen samt saett att korrigera foer baslinjedrift i systemet
GB8906776D0 (en) * 1989-03-23 1989-05-10 Amersham Int Plc Assay method using surface plasmon resonance spectrometry
SE9200917D0 (sv) * 1991-08-20 1992-03-25 Pharmacia Biosensor Ab Assay method

Also Published As

Publication number Publication date
AU4520093A (en) 1994-01-24
EP0648328B1 (de) 1998-01-21
DE69316620D1 (de) 1998-02-26
US5641640A (en) 1997-06-24
JPH07508346A (ja) 1995-09-14
ATE162627T1 (de) 1998-02-15
EP0648328A1 (de) 1995-04-19
SE9201984D0 (sv) 1992-06-29
WO1994000751A1 (en) 1994-01-06

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