DE69316636D1 - Implantierbarer und nachladbarer biohybrider, künstlicher pankreas - Google Patents

Implantierbarer und nachladbarer biohybrider, künstlicher pankreas

Info

Publication number
DE69316636D1
DE69316636D1 DE69316636T DE69316636T DE69316636D1 DE 69316636 D1 DE69316636 D1 DE 69316636D1 DE 69316636 T DE69316636 T DE 69316636T DE 69316636 T DE69316636 T DE 69316636T DE 69316636 D1 DE69316636 D1 DE 69316636D1
Authority
DE
Germany
Prior art keywords
pouch
islet
artificial pancreas
matrix
islets
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69316636T
Other languages
English (en)
Other versions
DE69316636T2 (de
Inventor
You Bae
Sung Kim
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Utah
Original Assignee
University of Utah
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Utah filed Critical University of Utah
Publication of DE69316636D1 publication Critical patent/DE69316636D1/de
Application granted granted Critical
Publication of DE69316636T2 publication Critical patent/DE69316636T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/022—Artificial gland structures using bioreactors
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
DE69316636T 1992-10-19 1993-09-28 Implantierbarer und nachladbarer biohybrider, künstlicher pankreas Expired - Fee Related DE69316636T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/962,879 US5262055A (en) 1992-10-19 1992-10-19 Implantable and refillable biohybrid artificial pancreas
PCT/US1993/009223 WO1994008702A1 (en) 1992-10-19 1993-09-28 Implantable and refillable biohybrid artificial pancreas

Publications (2)

Publication Number Publication Date
DE69316636D1 true DE69316636D1 (de) 1998-02-26
DE69316636T2 DE69316636T2 (de) 1998-05-07

Family

ID=25506457

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69316636T Expired - Fee Related DE69316636T2 (de) 1992-10-19 1993-09-28 Implantierbarer und nachladbarer biohybrider, künstlicher pankreas

Country Status (12)

Country Link
US (1) US5262055A (de)
EP (1) EP0664729B1 (de)
JP (1) JPH08504615A (de)
KR (1) KR100266833B1 (de)
AT (1) ATE162423T1 (de)
AU (1) AU5166193A (de)
CA (1) CA2147261A1 (de)
DE (1) DE69316636T2 (de)
DK (1) DK0664729T3 (de)
ES (1) ES2111775T3 (de)
GR (1) GR3026399T3 (de)
WO (1) WO1994008702A1 (de)

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US6231881B1 (en) 1992-02-24 2001-05-15 Anton-Lewis Usala Medium and matrix for long-term proliferation of cells
US6352707B1 (en) 1992-02-24 2002-03-05 Anton-Lewis Usala Transplant encapsulation in a hydrogel matrix to obscure immune recognition
WO1995008355A1 (en) * 1993-09-24 1995-03-30 Baxter International Inc. Methods for enhancing vascularization of implant devices
US5549675A (en) * 1994-01-11 1996-08-27 Baxter International, Inc. Method for implanting tissue in a host
US6090400A (en) * 1994-02-07 2000-07-18 The Trustees Of The Childhood Diabetes Transplant Research Trust Pharmaceutical preparation and method for treatment of diabetes
US6156305A (en) * 1994-07-08 2000-12-05 Baxter International Inc. Implanted tumor cells for the prevention and treatment of cancer
WO1996027662A1 (en) * 1995-03-03 1996-09-12 Metabolex, Inc. Novel encapsulation process by a gelling polymer
AU5390696A (en) * 1995-04-20 1996-11-07 University Of South Florida Purified and isolated sertoli cell aggregate
DK0830106T3 (da) * 1995-06-05 2002-07-29 Baxter Int Vævsladesystem til implanterbare biologiske indretninger
US5861313A (en) * 1995-06-07 1999-01-19 Ontogeny, Inc. Method of isolating bile duct progenitor cells
US5820917A (en) * 1995-06-07 1998-10-13 Medtronic, Inc. Blood-contacting medical device and method
US5702444A (en) * 1995-09-11 1997-12-30 Struthers, Mehta And Maxwell Implantable artificial endocrine pancreas
DE69634859D1 (de) * 1995-10-26 2005-07-21 Paul P Latta Induktion von immunologischer toleranz
CA2291622C (en) * 1997-06-06 2007-09-04 Anna Gutowska Reversible geling co-polymer and method of making
US6296831B1 (en) 1998-04-10 2001-10-02 Battelle Memorial Institute Stimulus sensitive gel with radioisotope and methods of making
US20040228794A1 (en) * 1998-04-10 2004-11-18 Battelle Memorial Institute Therapeutic agent carrier compositions
US7422601B2 (en) 1999-08-02 2008-09-09 University Of Chicago Office Of Technology Transfer Method for inducing hypothermia
EP1207807A4 (de) 1999-08-02 2005-12-28 Lance B Becker Verfahren zur induzierung von hypothermie
US6962601B2 (en) 1999-08-02 2005-11-08 University Of Chicago Office Of Technology Transfer Method for inducing hypothermia
US8012500B2 (en) * 2000-01-01 2011-09-06 Beta-O2 Technologies Ltd. Implantable device
IL134009A (en) * 2000-01-12 2011-07-31 Bo2 Technologies Ltd Transplant device
US20030167054A1 (en) * 2000-05-05 2003-09-04 Lawrence Rosenberg Device for cell implantation
EP1289537B1 (de) 2000-05-31 2005-11-30 Encelle, Inc. Verfahren zur behandlung von chronischen geschwüren
US6511473B2 (en) * 2001-01-30 2003-01-28 Biodepo, Inc. Implantable bioartificial active secretion system
KR100431536B1 (ko) * 2001-02-14 2004-05-20 박상규 ｐＨ변화를 이용한 식품 품질 식별표시계
CA2447763A1 (en) * 2001-06-08 2002-12-19 Boehringer Ingelheim Pharmaceuticals, Inc. Methods for improving cell line activity in immunoisolation devices
AU2003256896A1 (en) * 2002-08-07 2004-02-25 Memry Corporation Implantable artifical pancreas
AU2003294541A1 (en) * 2002-12-24 2004-07-22 An-Go-Gen Inc. Encapsulated cell for therapy
US20040185013A1 (en) * 2003-01-30 2004-09-23 Burgio Paul A. Dental whitening compositions and methods
US20040151691A1 (en) * 2003-01-30 2004-08-05 Oxman Joel D. Hardenable thermally responsive compositions
US7223826B2 (en) * 2003-01-30 2007-05-29 3M Innovative Properties Company Amide-functional polymers, compositions, and methods
US20040197374A1 (en) * 2003-04-02 2004-10-07 Alireza Rezania Implantable pouch seeded with insulin-producing cells to treat diabetes
US7820158B2 (en) * 2003-04-10 2010-10-26 Surmodics, Inc. Ligand-coupled initiator polymers and methods of use
US20060036302A1 (en) * 2004-05-28 2006-02-16 Kasza Kenneth E Methods of inducing protective hypothermia of organs
US9788978B2 (en) * 2004-12-20 2017-10-17 Nicholas A. Rojo Implantable systems and stents containing cells for therapeutic uses
US20060161232A1 (en) * 2005-01-18 2006-07-20 Kasza, Oras and Son to The University of Chicago Phase-change particulate ice slurry coolant medical delivery tubing and insertion devices
CN101282652B (zh) * 2005-06-02 2013-09-11 亚利桑那董事会（代表亚利桑那大学） 预血管化的装置及相关方法
US7389653B2 (en) * 2005-09-15 2008-06-24 The University Of Chicago Medical ice slurry production device
US20100068264A1 (en) * 2006-07-12 2010-03-18 University Of South Florida Niosome-hydrogel drug delivery system
DE102006042732B3 (de) * 2006-09-12 2008-04-10 Gerlach, Jörg, Dr.med. Künstliches arterio-venöses permeables Hohlfaserkapillarsystem
CN101517067B (zh) * 2006-09-21 2014-08-06 特苏詹尼斯公司 细胞递送基质
EP2104492B1 (de) * 2006-11-28 2017-11-22 Beta O2 Technologies Ltd. Sauerstoffzufuhr für ein zelltransplantat und vaskularisierung
US8702810B2 (en) * 2007-03-09 2014-04-22 The University Of Akron Bio-artificial pancreas and a procedure for preparation of same
US8821431B2 (en) * 2007-09-07 2014-09-02 Beta O2 Technologies Ltd. Air gap for supporting cells
US20090110656A1 (en) * 2007-10-31 2009-04-30 Lemke Sarah A Skin cooling composition
US20090157153A1 (en) * 2007-12-13 2009-06-18 Sarah Anne Lemke Skin cooling system
US20090324693A1 (en) * 2008-06-30 2009-12-31 Kimberly-Clark Worldwide, Inc. Delivery Product for Topical Compositions
US9540630B2 (en) * 2008-09-17 2017-01-10 Beta O2 Technologies Ltd. Optimization of alginate encapsulation of islets for transplantation
US9446168B2 (en) 2010-06-07 2016-09-20 Beta-O2 Technologies Ltd. Multiple-layer immune barrier for donor cells
CA3229301A1 (en) * 2008-11-14 2010-05-20 Viacyte, Inc. Encapsulation of pancreatic cells derived from human pluripotent stem cells
US8043271B2 (en) * 2008-11-26 2011-10-25 Beta 02 Technologies Ltd. Apparatus for transportation of oxygen to implanted cells
WO2010143651A1 (ja) 2009-06-09 2010-12-16 株式会社ジェイテック 回転培養ベッセル及びそれを用いた自動細胞培養装置
ES2653241T3 (es) 2009-08-28 2018-02-06 Sernova Corporation Métodos y dispositivos para trasplante celular
US8784389B2 (en) * 2009-08-31 2014-07-22 Beta-O2 Technologies Ltd. Oxygen supply for implantable medical device
US9597358B2 (en) 2010-03-04 2017-03-21 University of Pittsburgh—of the Commonwealth System of Higher Education Bioengineered human corneal stromal tissue
FR2960783B1 (fr) 2010-06-04 2012-07-27 Ass Pour Les Transferts De Technologies Du Mans Membrane fonctionnalisee pour chambre d'encapsulation de cellules produisant au moins une substance d'interet therapeutique et organe bioartificiel comprenant une telle membrane
FR2962898B1 (fr) * 2010-07-22 2012-08-17 Statice Sante Poche pour former un organe artificiel implantable
EP2782535B1 (de) * 2011-11-24 2016-10-19 Cook Biotech Incorporated Medizinische modifizierbare transplantate sowie entsprechende vorrichtungen
US20130158472A1 (en) * 2011-12-16 2013-06-20 JaiShankar Raman Subcutaneous Controlled Delivery System For The Topical Administration Of Drugs, Biological Agents Or Therapeutic Agents To Targeted Areas Within The Body
US9101707B2 (en) 2012-04-27 2015-08-11 Gregory Zeltser Implantable bioartificial perfusion system
US9522114B1 (en) 2014-03-27 2016-12-20 University Of South Florida Enhanced targeted drug delivery system via chitosan hydrogel and chlorotoxin
US10575765B2 (en) 2014-10-13 2020-03-03 Glusense Ltd. Analyte-sensing device
KR101681542B1 (ko) * 2015-03-10 2016-12-01 메디키네틱스 주식회사 인공췌장 구현을 위한 교환형 카트리지 장치
US10871487B2 (en) 2016-04-20 2020-12-22 Glusense Ltd. FRET-based glucose-detection molecules
EP3318294A1 (de) * 2016-11-08 2018-05-09 Defymed Kit zur in situ-ausgabe einer verbindung von interesse
US20180263238A1 (en) * 2017-03-20 2018-09-20 Boston Scientific Limited Cell encapsulation device
EP3428264A1 (de) 2017-07-12 2019-01-16 Defymed Nicht faltbarer beutel zur formung eines implantierbaren künstlichen organs
US11534283B2 (en) * 2017-09-06 2022-12-27 Children's National Medical Center Porous implantable devices
CN108659807B (zh) * 2018-07-12 2020-09-01 西安交通大学 一种智能纳米泡沫驱油剂的制备方法
WO2021061940A1 (en) 2019-09-27 2021-04-01 Isla Technologies, Inc. Bioartificial pancreas

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FR2531333B1 (fr) * 1982-08-09 1986-04-04 Centre Nat Rech Scient Pancreas bio-artificiel a ultrafiltration
JPH0489000A (ja) * 1990-05-02 1992-03-23 W R Grace & Co 細胞培養キットおよび細胞傷害試験法
EP0470681A3 (en) * 1990-08-08 1992-04-22 W.R. Grace & Co.-Conn. Cell clusters or sheets comprising a plurality of cell species and preparations thereof
EP0499932A1 (de) * 1991-02-16 1992-08-26 W.R. Grace & Co.-Conn. Tumorzellmasse, die Tumorzellen und Normalzellen enthält, und ihre Herstellung

Also Published As

Publication number Publication date
GR3026399T3 (en) 1998-06-30
US5262055A (en) 1993-11-16
EP0664729B1 (de) 1998-01-21
AU5166193A (en) 1994-05-09
EP0664729A1 (de) 1995-08-02
ES2111775T3 (es) 1998-03-16
KR100266833B1 (ko) 2000-09-15
KR950703399A (ko) 1995-09-20
WO1994008702A1 (en) 1994-04-28
JPH08504615A (ja) 1996-05-21
ATE162423T1 (de) 1998-02-15
EP0664729A4 (de) 1996-03-27
DE69316636T2 (de) 1998-05-07
DK0664729T3 (da) 1998-09-21
CA2147261A1 (en) 1994-04-28

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee