DE69320336T2 - Isolierung, Charakterisierung und Verwendung der menschlichen Beta-Einheit des Immunglobulin E-Hochaffinitätsrezeptors - Google Patents

Isolierung, Charakterisierung und Verwendung der menschlichen Beta-Einheit des Immunglobulin E-Hochaffinitätsrezeptors

Info

Publication number
DE69320336T2
DE69320336T2 DE69320336T DE69320336T DE69320336T2 DE 69320336 T2 DE69320336 T2 DE 69320336T2 DE 69320336 T DE69320336 T DE 69320336T DE 69320336 T DE69320336 T DE 69320336T DE 69320336 T2 DE69320336 T2 DE 69320336T2
Authority
DE
Germany
Prior art keywords
immunoglobulin
high affinity
characterization
isolation
affinity receptor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69320336T
Other languages
English (en)
Other versions
DE69320336D1 (de
Inventor
Jean Kinet
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
US Department of Health and Human Services
Original Assignee
US Department of Health and Human Services
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by US Department of Health and Human Services filed Critical US Department of Health and Human Services
Publication of DE69320336D1 publication Critical patent/DE69320336D1/de
Application granted granted Critical
Publication of DE69320336T2 publication Critical patent/DE69320336T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/70535—Fc-receptors, e.g. CD16, CD32, CD64 (CD2314/705F)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/283—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against Fc-receptors, e.g. CD16, CD32, CD64
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
DE69320336T 1992-04-16 1993-04-16 Isolierung, Charakterisierung und Verwendung der menschlichen Beta-Einheit des Immunglobulin E-Hochaffinitätsrezeptors Expired - Fee Related DE69320336T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/869,933 US5770396A (en) 1992-04-16 1992-04-16 Isolation characterization, and use of the human beta subunit of the high affinity receptor for immunoglobulin E
PCT/US1993/003419 WO1993021317A1 (en) 1992-04-16 1993-04-16 ISOLATION, CHARACTERIZATION, AND USE OF THE HUMAN β SUBUNIT OF THE HIGH AFFINITY RECEPTOR FOR IMMUNOGLOBULIN E

Publications (2)

Publication Number Publication Date
DE69320336D1 DE69320336D1 (de) 1998-09-17
DE69320336T2 true DE69320336T2 (de) 1999-04-08

Family

ID=25354480

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69320336T Expired - Fee Related DE69320336T2 (de) 1992-04-16 1993-04-16 Isolierung, Charakterisierung und Verwendung der menschlichen Beta-Einheit des Immunglobulin E-Hochaffinitätsrezeptors

Country Status (8)

Country Link
US (3) US5770396A (de)
EP (1) EP0636177B1 (de)
JP (1) JP3534406B2 (de)
AT (1) ATE169676T1 (de)
AU (1) AU676680B2 (de)
CA (1) CA2118329C (de)
DE (1) DE69320336T2 (de)
WO (1) WO1993021317A1 (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5770396A (en) 1992-04-16 1998-06-23 The United States Of America As Represented By The Department Of Health And Human Services Isolation characterization, and use of the human beta subunit of the high affinity receptor for immunoglobulin E
IL111105A (en) * 1993-09-30 2009-05-04 Univ Pennsylvania Use of a molecule capable of inhibiting the expression of syk kinase to prepare a pharmaceutical composition for inhibiting phagocytosis
US5858981A (en) 1993-09-30 1999-01-12 University Of Pennsylvania Method of inhibiting phagocytosis
EP0804218A1 (de) * 1994-03-17 1997-11-05 National Jewish Center For Immunology And Respiratory Medicine Produkt und Verfahren zur Regulierung von Signalübertragungswegen
GB9510718D0 (en) * 1995-05-26 1995-07-19 Sod Conseils Rech Applic Antisense oligonucleotides
US5708156A (en) * 1996-05-31 1998-01-13 Ilekis; John V. Epidermal growth factor receptor-like gene product and its uses
US5945294A (en) * 1996-11-26 1999-08-31 Heska Corporation Method to detect IgE
US5871930A (en) * 1997-08-21 1999-02-16 Incyte Pharmaceuticals, Inc. High affinity immunoglobulin E receptor-like protein
US6057127A (en) * 1998-01-29 2000-05-02 Heska Corporation Equine Fc epsilon receptor alpha chain nucleic acid molecules and uses thereof
US6299875B1 (en) * 1998-06-04 2001-10-09 Panacea Pharmaceuticals, Llc Methods to block IGE binding to cell surface receptors of mast cells
AU766882B2 (en) * 1999-02-25 2003-10-23 National Jewish Medical And Research Center Product and method for treatment of conditions associated with receptor-desensitization
WO2001011010A2 (en) * 1999-08-09 2001-02-15 Genaissance Pharmaceuticals, Inc. Drug target isogenes: polymorphisms in the immunoglobulin e receptor i alpha subunit gene
WO2001014588A1 (en) * 1999-08-24 2001-03-01 Genaissance Pharmaceuticals, Inc. Drug target isogenes: polymorphisms in the immunoglobulin e receptor beta chain gene
WO2001021816A1 (en) * 1999-09-21 2001-03-29 Isis Innovation Limited MODULATION OF IgE RECEPTOR CELL SURFACE EXPRESSION
AU2001234797A1 (en) * 2000-02-02 2001-08-14 Biogen, Inc. Novel high affinity immunoglobulin epsilon receptor beta-subunit-like protein and nucleic acids encoding same
US20030022250A1 (en) * 2001-05-29 2003-01-30 Dreskin Stephen C. Functional IgE test methods and compositions
JPWO2004108929A1 (ja) * 2003-06-04 2006-07-20 学校法人日本大学 高親和性ＩｇＥ受容体β鎖発現調節
EP1935977A4 (de) * 2005-09-20 2009-05-06 Univ Nihon Transkriptionale regulation der hochaffinen ige-rezeptor-kette
EP3279315A3 (de) * 2012-05-25 2018-02-28 Cellectis Verwendung von prä-alpha-t oder einer funktionellen variante davon zur erweiterung von t-zellen mit tcr-alpha-mangel
EP2893004B1 (de) * 2012-09-04 2018-10-24 Cellectis Chimärer mehrsträngiger antigenrezeptor und verwendungen davon

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4171299A (en) * 1975-04-04 1979-10-16 The Regents Of The University Of California Polypeptide agents for blocking the human allergic response
US4620948A (en) 1982-12-22 1986-11-04 Genentech, Inc. Purification and activity assurance of precipitated heterologous proteins
US4477446A (en) * 1983-07-01 1984-10-16 Usv Pharmaceutical Corporation 1-Benzazepines and their pharmaceutical uses
US4946788A (en) * 1985-06-11 1990-08-07 Ciba-Geigy Corporation Purified immunoglobulin-related factor, novel monoclonal antibodies, hybridoma cell lines, processes and applications
EP0286700A1 (de) * 1987-04-11 1988-10-19 Kishimoto, Tadamitsu, Prof. Biologisch aktives rekombiniertes menschliches auflösbares FcR-Fragment, dieses FcR-Fragment kodierendes Plasmid sowie dessen Herstellung
US4940782A (en) * 1987-06-08 1990-07-10 G. D. Searle & Co. Monoclonal antibodies against IgE-associated determinants, hybrid cell lines producing these antibodies, and use therefore
US4962035A (en) * 1987-12-01 1990-10-09 President And Fellows Of Harvard College DNA encoding IgE receptor alpha-subunit or fragment thereof
EP0321601A1 (de) * 1987-12-22 1989-06-28 Kishimoto, Tadamitsu, Prof. Auflösbarer rekombinierter Fc-Epsilon-Rezeptor, dessen Herstellung und Verwendung
US5091313A (en) * 1988-08-05 1992-02-25 Tanox Biosystems, Inc. Antigenic epitopes of IgE present on B cell but not basophil surface
CA2000878C (en) * 1988-10-18 1999-06-29 Jean-Pierre Kinet Cdnas coding for the subunit of the high-affinity receptor for immunoglobulin e
CA2059842A1 (en) * 1991-02-11 1992-08-12 Richard A. Chizzonite Ige-receptor-antibodies
ES2296839T3 (es) * 1991-08-14 2008-05-01 Genentech Inc. Variantes de inmunoglobulinas para receptores fc-epsilon especificos.
US5770396A (en) 1992-04-16 1998-06-23 The United States Of America As Represented By The Department Of Health And Human Services Isolation characterization, and use of the human beta subunit of the high affinity receptor for immunoglobulin E

Also Published As

Publication number Publication date
WO1993021317A1 (en) 1993-10-28
DE69320336D1 (de) 1998-09-17
JP3534406B2 (ja) 2004-06-07
ATE169676T1 (de) 1998-08-15
AU4283493A (en) 1993-11-18
CA2118329A1 (en) 1993-10-28
EP0636177A1 (de) 1995-02-01
CA2118329C (en) 2005-11-29
US5807988A (en) 1998-09-15
EP0636177B1 (de) 1998-08-12
AU676680B2 (en) 1997-03-20
US5770396A (en) 1998-06-23
JPH07506486A (ja) 1995-07-20
US6171803B1 (en) 2001-01-09

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee