DE69324499D1 - Austragevorrichtung - Google Patents

Austragevorrichtung

Info

Publication number
DE69324499D1
DE69324499D1 DE69324499T DE69324499T DE69324499D1 DE 69324499 D1 DE69324499 D1 DE 69324499D1 DE 69324499 T DE69324499 T DE 69324499T DE 69324499 T DE69324499 T DE 69324499T DE 69324499 D1 DE69324499 D1 DE 69324499D1
Authority
DE
Germany
Prior art keywords
delivery
respiratory tract
liquids
discharge device
droplets
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69324499T
Other languages
English (en)
Other versions
DE69324499T2 (de
Inventor
Ronald Alan Coffee
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Battelle Memorial Institute Inc
Original Assignee
Electrosols Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Electrosols Ltd filed Critical Electrosols Ltd
Application granted granted Critical
Publication of DE69324499D1 publication Critical patent/DE69324499D1/de
Publication of DE69324499T2 publication Critical patent/DE69324499T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B05SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05BSPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B5/00Electrostatic spraying apparatus; Spraying apparatus with means for charging the spray electrically; Apparatus for spraying liquids or other fluent materials by other electric means
    • B05B5/002Electrostatic spraying apparatus; Spraying apparatus with means for charging the spray electrically; Apparatus for spraying liquids or other fluent materials by other electric means comprising means for neutralising the spray of charged droplets or particules
    • B05B5/003Electrostatic spraying apparatus; Spraying apparatus with means for charging the spray electrically; Apparatus for spraying liquids or other fluent materials by other electric means comprising means for neutralising the spray of charged droplets or particules by mixing two sprays of opposite polarity
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/02Inhalators with activated or ionised fluids, e.g. electrohydrodynamic [EHD] or electrostatic devices; Ozone-inhalators with radioactive tagged particles
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B05SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05BSPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B5/00Electrostatic spraying apparatus; Spraying apparatus with means for charging the spray electrically; Apparatus for spraying liquids or other fluent materials by other electric means
    • B05B5/025Discharge apparatus, e.g. electrostatic spray guns
    • B05B5/0255Discharge apparatus, e.g. electrostatic spray guns spraying and depositing by electrostatic forces only
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B05SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05BSPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B5/00Electrostatic spraying apparatus; Spraying apparatus with means for charging the spray electrically; Apparatus for spraying liquids or other fluent materials by other electric means
    • B05B5/025Discharge apparatus, e.g. electrostatic spray guns
    • B05B5/053Arrangements for supplying power, e.g. charging power
    • B05B5/0531Power generators
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B05SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05BSPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B5/00Electrostatic spraying apparatus; Spraying apparatus with means for charging the spray electrically; Apparatus for spraying liquids or other fluent materials by other electric means
    • B05B5/16Arrangements for supplying liquids or other fluent material
DE69324499T 1992-12-01 1993-11-26 Austragevorrichtung Expired - Lifetime DE69324499T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB929225098A GB9225098D0 (en) 1992-12-01 1992-12-01 Charged droplet spray mixer
PCT/GB1993/002443 WO1994012285A2 (en) 1992-12-01 1993-11-26 Dispensing device

Publications (2)

Publication Number Publication Date
DE69324499D1 true DE69324499D1 (de) 1999-05-20
DE69324499T2 DE69324499T2 (de) 1999-08-12

Family

ID=10725936

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69324499T Expired - Lifetime DE69324499T2 (de) 1992-12-01 1993-11-26 Austragevorrichtung

Country Status (19)

Country Link
US (2) US6105877A (de)
EP (1) EP0671980B1 (de)
JP (1) JPH08504126A (de)
KR (1) KR100289783B1 (de)
CN (1) CN1104262C (de)
AT (1) ATE178814T1 (de)
AU (1) AU685411B2 (de)
CA (1) CA2150692C (de)
DE (1) DE69324499T2 (de)
DK (1) DK0671980T3 (de)
ES (1) ES2130393T3 (de)
GB (1) GB9225098D0 (de)
GR (1) GR3030735T3 (de)
HK (1) HK1012301A1 (de)
MX (1) MX9307490A (de)
NZ (2) NZ314209A (de)
TW (1) TW242576B (de)
WO (1) WO1994012285A2 (de)
ZA (1) ZA938895B (de)

Families Citing this family (156)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9225098D0 (en) 1992-12-01 1993-01-20 Coffee Ronald A Charged droplet spray mixer
US6105571A (en) 1992-12-22 2000-08-22 Electrosols, Ltd. Dispensing device
GB9410658D0 (en) * 1994-05-27 1994-07-13 Electrosols Ltd Dispensing device
US5758637A (en) 1995-08-31 1998-06-02 Aerogen, Inc. Liquid dispensing apparatus and methods
US5863497A (en) * 1996-03-11 1999-01-26 The Proctor & Gamble Company Electrostatic hand sanitizer
WO1997033527A1 (en) * 1996-03-11 1997-09-18 The Procter & Gamble Company Electrostatic hand sanitizer
US20080119772A1 (en) 2001-01-11 2008-05-22 Ronald Alan Coffee Dispensing device and method for forming material
CA2296334C (en) 1996-07-23 2010-03-16 Electrosols Ltd. A dispensing device and method for forming material
US6252129B1 (en) 1996-07-23 2001-06-26 Electrosols, Ltd. Dispensing device and method for forming material
US6433154B1 (en) 1997-06-12 2002-08-13 Bristol-Myers Squibb Company Functional receptor/kinase chimera in yeast cells
GB2327895B (en) 1997-08-08 2001-08-08 Electrosols Ltd A dispensing device
EP1028349A1 (de) * 1997-10-27 2000-08-16 Sekisui Chemical Co., Ltd. Gerät zum versprühen von mikropartikeln und ein sprühverfahren unter verwendungdieses geräts sowie ein verfahren zur herstellung einer flüssigkristallanzeige
JP3681561B2 (ja) * 1997-12-26 2005-08-10 日本碍子株式会社 物質の均一混合方法及び混合装置
SE512386C2 (sv) * 1998-07-30 2000-03-06 Microdrug Ag Förfarande och anordning för klassificering av elektrostatiskt laddat pulverformigt material
GB2345010B (en) * 1998-12-17 2002-12-31 Electrosols Ltd A delivery device
US20040116032A1 (en) * 1999-02-25 2004-06-17 Bowlin Gary L. Electroprocessed collagen
US20020081732A1 (en) * 2000-10-18 2002-06-27 Bowlin Gary L. Electroprocessing in drug delivery and cell encapsulation
US7615373B2 (en) * 1999-02-25 2009-11-10 Virginia Commonwealth University Intellectual Property Foundation Electroprocessed collagen and tissue engineering
US6592623B1 (en) 1999-08-31 2003-07-15 Virginia Commonwealth University Intellectual Property Foundation Engineered muscle
EP1194244B1 (de) * 1999-04-23 2005-12-21 Battelle Memorial Institute Richtungsverstellbarer ehd- aerosol-zerstäuber
US6495015B1 (en) * 1999-06-18 2002-12-17 Sandia National Corporation Electrokinetically pumped high pressure sprays
US6235177B1 (en) 1999-09-09 2001-05-22 Aerogen, Inc. Method for the construction of an aperture plate for dispensing liquid droplets
JP2003523330A (ja) * 2000-02-04 2003-08-05 チルドレンズ・ホスピタル・リサーチ・ファウンデイション アテローム性動脈硬化症および関連疾患のための脂質加水分解治療
AU4439101A (en) * 2000-04-03 2001-10-15 Electrosols Ltd Devices and formulations
US8336545B2 (en) 2000-05-05 2012-12-25 Novartis Pharma Ag Methods and systems for operating an aerosol generator
US7971588B2 (en) 2000-05-05 2011-07-05 Novartis Ag Methods and systems for operating an aerosol generator
CA2409093C (en) 2000-05-16 2009-07-21 Regents Of The University Of Minnesota High mass throughput particle generation using multiple nozzle spraying
US6339107B1 (en) 2000-08-02 2002-01-15 Syntex (U.S.A.) Llc Methods for treatment of Emphysema using 13-cis retinoic acid
EP1315756A2 (de) * 2000-09-01 2003-06-04 Virginia Commonwealth University Intellectual Property Foundation Elektroplattierte fibrin-basierte träger und gewebe
EP1935869A1 (de) 2000-10-02 2008-06-25 F. Hoffmann-La Roche Ag Retinoide zur Behandlung von Emphysem
AU3664102A (en) * 2000-12-01 2002-06-11 Battelle Memorial Institute Method for stabilizing biomolecules in liquid formulations
US7674429B2 (en) * 2001-01-22 2010-03-09 Johnsondiversey, Inc. Electrostatic disinfectant delivery
US6546927B2 (en) * 2001-03-13 2003-04-15 Aerogen, Inc. Methods and apparatus for controlling piezoelectric vibration
JP2005501810A (ja) 2001-03-22 2005-01-20 バテル メモリアル インスティチュート ポリマーおよび懸濁粒子を含有する電気流体力学的噴霧用の液体形成物
US7247338B2 (en) * 2001-05-16 2007-07-24 Regents Of The University Of Minnesota Coating medical devices
AU2002310054B2 (en) * 2001-05-21 2007-02-01 Injet Digital Aerosols Limited Compositions for protein delivery via the pulmonary route
EP1273346A1 (de) * 2001-07-05 2003-01-08 Seyonic SA Mehrkanalige Vorrichtung zum Abgeben von Fluiden
US20030017359A1 (en) * 2001-07-17 2003-01-23 American Air Liquide, Inc. Increased stability low concentration gases, products comprising same, and methods of making same
US7832550B2 (en) 2001-07-17 2010-11-16 American Air Liquide, Inc. Reactive gases with concentrations of increased stability and processes for manufacturing same
WO2003008664A2 (en) * 2001-07-17 2003-01-30 L'air Liquide-Societe Anonyme A Directoire Et Conseil De Surveillance Pour L'etude Et L'exploitation Des Procedes Georges Claude Method of making a passivated surface
CA2472644C (en) 2002-01-07 2013-11-05 Aerogen, Inc. Devices and methods for nebulizing fluids for inhalation
US7677467B2 (en) 2002-01-07 2010-03-16 Novartis Pharma Ag Methods and devices for aerosolizing medicament
ES2603067T3 (es) 2002-01-15 2017-02-23 Novartis Ag Métodos y sistemas para hacer funcionar un generador de aerosol
AU2002234776A1 (en) 2002-03-01 2003-09-16 Unilever Plc Electrostatic spraying of a cosmetic composition
EP1509259B1 (de) 2002-05-20 2016-04-20 Novartis AG Gerät zur bereitstellung eines aerosols für die medizinische behandlung und verfahren
EP1512000A1 (de) * 2002-05-29 2005-03-09 L'air liquide, Société anonyme à Directoire et Conseil de Surveillance pour l'Etude et l'Exploitation des Procédés G. Claude Sauergas und matrixgas enthaltende zusammensetzungen mit reduzierter feuchtigkeit, diese zusammensetzungen enthaltende herstellungsartikel und verfahren zu ihrer herstellung
DE10228280A1 (de) * 2002-06-25 2004-01-29 Institut für Chemo- und Biosensorik Münster e.V. i.Ins. Vorrichtung und Verfahren zur Beschichtung dreidimensional strukturierter Oberflächen von Substraten
US20060179491A1 (en) * 2002-11-12 2006-08-10 Brian Graham Process for treating non-human animals
ZA200504940B (en) 2003-01-28 2006-09-27 Xenoport Inc Amino acid derived prodrugs of propofol, compositions and uses thereof
US7849850B2 (en) * 2003-02-28 2010-12-14 Battelle Memorial Institute Nozzle for handheld pulmonary aerosol delivery device
AU2004220457A1 (en) 2003-03-12 2004-09-23 Celgene Corporation 7-amino- isoindolyl compounds amd their pharmaceutical uses
EP1462801A3 (de) * 2003-03-24 2005-01-05 Tepnel Lifecodes Methoden zur messung der negativkontrolle in mehrfachanalyt-assays
GB0307403D0 (en) 2003-03-31 2003-05-07 Medical Res Council Selection by compartmentalised screening
GB0307428D0 (en) 2003-03-31 2003-05-07 Medical Res Council Compartmentalised combinatorial chemistry
US20060078893A1 (en) 2004-10-12 2006-04-13 Medical Research Council Compartmentalised combinatorial chemistry by microfluidic control
GB0308021D0 (en) * 2003-04-07 2003-05-14 Aerstream Technology Ltd Spray electrode
EP3103800B1 (de) 2003-04-11 2018-06-13 PTC Therapeutics, Inc. 1,2,4-oxadiazolbenzoesäureverbindung und deren verwendung zur nonsense-unterdrückung und behandlung von krankheiten
US8616195B2 (en) 2003-07-18 2013-12-31 Novartis Ag Nebuliser for the production of aerosolized medication
DE10334591B4 (de) * 2003-07-28 2006-03-30 International Flavors & Fragrances Inc. Verfahren zum Verteilen von flüssigen Duftstoffen und Vorrichtung zur Durchführung des Verfahrens
WO2005023204A2 (en) 2003-09-09 2005-03-17 Xenoport, Inc. Aromatic prodrugs of propofol, compositions and uses thereof
DE10344135A1 (de) * 2003-09-24 2005-05-04 Karlsruhe Forschzent Vorrichtung zum Aufbringen von Elektrospraybeschichtungen auf elektrisch nicht leitfähigen Oberflächen
US20050079113A1 (en) * 2003-10-09 2005-04-14 Selander Raymond K. Fan-driven air freshener
DE10349472B4 (de) * 2003-10-21 2006-01-19 Forschungszentrum Karlsruhe Gmbh Beschichtungsvorrichtung für Polymere
EP1692128A1 (de) 2003-11-19 2006-08-23 Signal Pharmaceuticals LLC Indazolverbindungen und verfahren zu deren anwendung als proteinkinaseinhibitoren
NL1025556C1 (nl) * 2004-02-24 2005-08-26 Jacob Korevaar Inrichting en werkwijze voor het toedienen van een fluïdum aan een mens of zoogdier.
US20050221339A1 (en) 2004-03-31 2005-10-06 Medical Research Council Harvard University Compartmentalised screening by microfluidic control
US7946291B2 (en) 2004-04-20 2011-05-24 Novartis Ag Ventilation systems and methods employing aerosol generators
WO2006017351A1 (en) 2004-07-12 2006-02-16 Xenoport, Inc. Prodrugs of propofol, compositions and uses thereof
US7550506B2 (en) 2004-07-12 2009-06-23 Xenoport, Inc. Amino acid derived prodrugs of propofol, compositions and uses thereof
WO2006032018A2 (en) 2004-09-14 2006-03-23 Battelle Memorial Institute Highly-aqueous non-respirable aerosols containing biologically-active ingredients method of making and device therefor
US7968287B2 (en) 2004-10-08 2011-06-28 Medical Research Council Harvard University In vitro evolution in microfluidic systems
US7360724B2 (en) 2004-10-20 2008-04-22 The Procter & Gamble Company Electrostatic spray nozzle with internal and external electrodes
PT2561872E (pt) 2004-12-17 2014-12-18 Anadys Pharmaceuticals Inc Compostos 3h-oxazolo[4,5-d]pirimidin-2-ona 3,5-di- -substituídos e 3,5,7-tri-substituídos e seus pró-fármacos
FR2879482B1 (fr) * 2004-12-20 2007-03-30 Oreal Dispositif de pulverisation d'un produit, notamment d'un parfum
ATE456552T1 (de) 2004-12-23 2010-02-15 Xenoport Inc Von serinaminosäure abgeleitete prodrugs von propofol, zusammensetzungen, anwendungen und kristalline formen davon
MX2007009668A (es) * 2005-02-11 2007-09-26 Battelle Memorial Institute Dispositivo distribuidor de aerosol electrohidrodinamico y metodo de pulverizacion.
US7208611B2 (en) 2005-02-23 2007-04-24 Xenoport, Inc. Platinum-containing compounds exhibiting cytostatic activity, synthesis and methods of use
DE102005016829A1 (de) 2005-04-12 2006-11-02 Iff International Flavors & Fragrances Verfahren, Düse und Vorrichtung zur Zerstäubung von in einer Flüssigkeit enthaltenen Wirkstoffen
JP5064383B2 (ja) 2005-05-25 2012-10-31 エアロジェン,インコーポレイテッド 振動システムと方法
EP1928881A2 (de) 2005-08-19 2008-06-11 Pharmacofore, Inc. Prodrugs von wirkstoffen
US20090297496A1 (en) * 2005-09-08 2009-12-03 Childrens Hospital Medical Center Lysosomal Acid Lipase Therapy for NAFLD and Related Diseases
GB0524979D0 (en) 2005-12-07 2006-01-18 Queen Mary & Westfield College An electrospray device and a method of electrospraying
EP2363205A3 (de) 2006-01-11 2014-06-04 Raindance Technologies, Inc. Mikrofluidische Vorrichtungen Und Verfahren Zur Verwendung Bei Der Bildung Und Kontrolle Von Nanoreaktoren
CA2637883C (en) * 2006-01-31 2015-07-07 Regents Of The University Of Minnesota Electrospray coating of objects
EP1988941A2 (de) 2006-01-31 2008-11-12 Nanocopoeia, Inc. Oberflächenbeschichtung mit nanoteilchen
US9108217B2 (en) 2006-01-31 2015-08-18 Nanocopoeia, Inc. Nanoparticle coating of surfaces
WO2007094835A1 (en) 2006-02-14 2007-08-23 Ventaira Pharmaceuticals, Inc. Dissociated discharge ehd sprayer with electric field shield
EP2004619A1 (de) 2006-03-23 2008-12-24 Amgen Inc. Heterocyclische 1-phenylsulfonyl-diaza-amidverbindungen und ihre verwendung als modulatoren von hydroxsteroid-dehydrogenasen
DE102006017002B3 (de) * 2006-04-11 2007-01-11 Pari GmbH Spezialisten für effektive Inhalation Inhalationstherapievorrichtung mit mehrfachen Düsen
EP2530168B1 (de) 2006-05-11 2015-09-16 Raindance Technologies, Inc. Mikrofluidische Vorrichtungen
US9562837B2 (en) 2006-05-11 2017-02-07 Raindance Technologies, Inc. Systems for handling microfludic droplets
WO2007140272A2 (en) 2006-05-26 2007-12-06 Pharmacofore, Inc. Controlled release of phenolic opioids
DE602007008237D1 (de) 2006-06-08 2010-09-16 Amgen Inc Benzamidderivate und assoziierte verwendungen
TW200808695A (en) 2006-06-08 2008-02-16 Amgen Inc Benzamide derivatives and uses related thereto
US7673819B2 (en) * 2006-06-26 2010-03-09 Battelle Memorial Institute Handheld sprayer with removable cartridge and method of using same
CA2656000C (en) 2006-06-22 2016-09-06 Anadys Pharmaceuticals, Inc. Pyrro[1,2-b]pyridazinone compounds
US7709448B2 (en) 2006-06-22 2010-05-04 Anadys Pharmaceuticals, Inc. Prodrugs of 5-amino-3-(3′-deoxy-β-D-ribofuranosyl)-thiazolo[4,5-d]pyrimidin-2,7-dione
WO2008002556A1 (en) * 2006-06-26 2008-01-03 Battelle Memorial Institute Cartridge having self-actuating seal for a wetted lead screw
EP2040712B1 (de) 2006-07-18 2011-03-02 Anadys Pharmaceuticals, Inc. Carbonat- und carbamat-prodrugs von thiazolo [4,5-d]-pyrimidinen
CA2659155A1 (en) 2006-07-20 2008-01-24 Amgen Inc. Substituted azole aromatic heterocycles as inhibitors of 11.beta.-hsd-1
WO2008021123A1 (en) 2006-08-07 2008-02-21 President And Fellows Of Harvard College Fluorocarbon emulsion stabilizing surfactants
US9040816B2 (en) * 2006-12-08 2015-05-26 Nanocopoeia, Inc. Methods and apparatus for forming photovoltaic cells using electrospray
FR2910253B1 (fr) * 2006-12-20 2010-03-12 Oreal Procede de distribution d'un produit pulverise par un systeme de pulverisation piezoelectrique et systeme de pulverisation pour la mise en oeuvre d'un tel procede
FR2910254B1 (fr) * 2006-12-20 2009-04-17 Oreal Systeme de pulverisation piezoelectrique et recharge correspondante
AU2007343726A1 (en) 2006-12-26 2008-07-24 Amgen Inc. N-cyclohexyl benzamides and benzeneacetamides as inhibitors of 11-beta-hydroxysteroid dehydrogenases
WO2008094700A2 (en) * 2007-01-31 2008-08-07 Nanocopoeia, Inc. Nanoparticle coating of surfaces
WO2008097559A2 (en) 2007-02-06 2008-08-14 Brandeis University Manipulation of fluids and reactions in microfluidic systems
WO2008130623A1 (en) 2007-04-19 2008-10-30 Brandeis University Manipulation of fluids, fluid components and reactions in microfluidic systems
US20080269665A1 (en) * 2007-04-24 2008-10-30 Johan Petersen Chemotherapy delivery device
GB0709517D0 (en) 2007-05-17 2007-06-27 Queen Mary & Westfield College An electrostatic spraying device and a method of electrostatic spraying
EP4047367A1 (de) 2008-07-18 2022-08-24 Bio-Rad Laboratories, Inc. Verfahren zum nachweis von zielanalyten unter verwendung von tropfenbibliotheken
ES2435799T3 (es) 2008-10-09 2013-12-23 Anadys Pharmaceuticals, Inc. Un método de inhibición del virus de la hepatitis C mediante combinación de una 5,6-dihidro-1H-piridin-2-ona y de uno o más compuestos antivirales adicionales
ITRM20090039A1 (it) * 2009-01-29 2010-07-30 Uni Degli Studi Di Roma To R Vergata Sistema di dispersione di micro o nanoparticelle solide in una fase liquida
GB0903134D0 (en) * 2009-02-24 2009-04-08 Osmotex Ag Charged particle motion inducing apparatus
EP3415235A1 (de) 2009-03-23 2018-12-19 Raindance Technologies Inc. Manipulation von mikrofluidiktröpfchen
WO2011042564A1 (en) 2009-10-09 2011-04-14 Universite De Strasbourg Labelled silica-based nanomaterial with enhanced properties and uses thereof
EP2517025B1 (de) 2009-12-23 2019-11-27 Bio-Rad Laboratories, Inc. Verfahren zur reduzierung des austauschs von molekülen zwischen tröpfchen
US20110174304A1 (en) * 2010-01-21 2011-07-21 Triplett Ii Michael D Electrohydrodynamic aerosolization device having a time varying voltage
US9399797B2 (en) 2010-02-12 2016-07-26 Raindance Technologies, Inc. Digital analyte analysis
US9366632B2 (en) 2010-02-12 2016-06-14 Raindance Technologies, Inc. Digital analyte analysis
US10351905B2 (en) 2010-02-12 2019-07-16 Bio-Rad Laboratories, Inc. Digital analyte analysis
EP2534267B1 (de) 2010-02-12 2018-04-11 Raindance Technologies, Inc. Digitale analyse von analyten
JP5429993B2 (ja) * 2010-03-04 2014-02-26 国立大学法人東京工業大学 匂い発生装置
EP2561333B1 (de) 2010-04-19 2015-11-25 Battelle Memorial Institute Elektrohydrodynamisches sprühen
US9562897B2 (en) 2010-09-30 2017-02-07 Raindance Technologies, Inc. Sandwich assays in droplets
US9364803B2 (en) 2011-02-11 2016-06-14 Raindance Technologies, Inc. Methods for forming mixed droplets
US9150852B2 (en) 2011-02-18 2015-10-06 Raindance Technologies, Inc. Compositions and methods for molecular labeling
WO2012158271A1 (en) 2011-04-06 2012-11-22 Anadys Pharmaceuticals, Inc. Bridged polycyclic compounds as antiviral agents
US8841071B2 (en) 2011-06-02 2014-09-23 Raindance Technologies, Inc. Sample multiplexing
EP3709018A1 (de) 2011-06-02 2020-09-16 Bio-Rad Laboratories, Inc. Mikrofluidische vorrichtung zum nachweis von komponenten einer chemischen reaktion
WO2012173262A1 (ja) * 2011-06-16 2012-12-20 独立行政法人産業技術総合研究所 エレクトロスプレーによるマイクロ反応場形成装置及び化学反応制御方法
US8658430B2 (en) 2011-07-20 2014-02-25 Raindance Technologies, Inc. Manipulating droplet size
JP5762872B2 (ja) * 2011-07-29 2015-08-12 住友化学株式会社 静電噴霧装置
US10350409B2 (en) 2013-03-15 2019-07-16 Ottfried Waldenburg Instrument for and method of treating venomous bites
US20150053786A1 (en) * 2013-08-21 2015-02-26 Trimble Navigation Limited Intelligent precision irrigation system
US11901041B2 (en) 2013-10-04 2024-02-13 Bio-Rad Laboratories, Inc. Digital analysis of nucleic acid modification
US9944977B2 (en) 2013-12-12 2018-04-17 Raindance Technologies, Inc. Distinguishing rare variations in a nucleic acid sequence from a sample
US11193176B2 (en) 2013-12-31 2021-12-07 Bio-Rad Laboratories, Inc. Method for detecting and quantifying latent retroviral RNA species
CN104138630B (zh) * 2014-07-30 2017-05-10 北京银河之舟科技有限公司 一种呼吸道给药的装置及方法
JP6083031B2 (ja) * 2015-05-15 2017-02-22 国立研究開発法人産業技術総合研究所 液中エレクトロスプレー法及び液中エレクトロスプレー装置
US10647981B1 (en) 2015-09-08 2020-05-12 Bio-Rad Laboratories, Inc. Nucleic acid library generation methods and compositions
US9808452B2 (en) 2015-10-01 2017-11-07 Elysium Therapeutics, Inc. Polysubunit opioid prodrugs resistant to overdose and abuse
US10335406B2 (en) 2015-10-01 2019-07-02 Elysium Therapeutics, Inc. Opioid compositions resistant to overdose and abuse
US20170095834A1 (en) * 2015-10-05 2017-04-06 William Brian Kinard Electrostatic deposition
US10433580B2 (en) 2016-03-03 2019-10-08 Altria Client Services Llc Methods to add menthol, botanic materials, and/or non-botanic materials to a cartridge, and/or an electronic vaping device including the cartridge
US10455863B2 (en) 2016-03-03 2019-10-29 Altria Client Services Llc Cartridge for electronic vaping device
US10368580B2 (en) 2016-03-08 2019-08-06 Altria Client Services Llc Combined cartridge for electronic vaping device
US10368581B2 (en) 2016-03-11 2019-08-06 Altria Client Services Llc Multiple dispersion generator e-vaping device
US10357060B2 (en) 2016-03-11 2019-07-23 Altria Client Services Llc E-vaping device cartridge holder
EP3595663A4 (de) 2017-03-17 2021-01-13 Elysium Therapeutics, Inc. Mehrfachuntereinheit-opioid-prodrugs mit resistenz gegen überdosierung und missbrauch
US10933084B2 (en) 2018-04-12 2021-03-02 MatRx Therapeutics Corporation Compositions and methods for treating elastic fiber breakdown
CN109037023B (zh) * 2018-06-06 2020-03-10 清华大学深圳研究生院 一种用于产生中性喷雾的装置、方法和物质检测设备
WO2020080347A1 (ja) * 2018-10-17 2020-04-23 住友化学株式会社 静電噴霧装置
CN110755699A (zh) * 2019-09-18 2020-02-07 浙江省北大信息技术高等研究院 可植入的电渗微泵装置
CN111388018B (zh) * 2020-03-20 2023-09-19 威图姆卡医疗中心 采集下呼吸道样本的方法及其装置、空气消毒方法及其装置
GB2598964A (en) * 2020-09-22 2022-03-23 Brian King Andrew Methods and apparatus for inducing chemical reactions using electro-statics

Family Cites Families (79)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2723646A (en) * 1950-04-01 1955-11-15 Ransburg Electro Coating Corp Apparatus for electrostatic atomization and coating
US2945443A (en) * 1957-08-22 1960-07-19 Gen Electric Pump operation
US3096762A (en) 1962-02-12 1963-07-09 Waterbury Pressed Metal Co Oral breathing device
US3131131A (en) * 1962-04-03 1964-04-28 Socony Mobil Oil Co Inc Electrostatic mixing in microbial conversions
US3232292A (en) 1962-10-12 1966-02-01 Arizona Nucleonics Inc Ionized aerosols
US3456646A (en) 1967-01-19 1969-07-22 Dart Ind Inc Inhalation-actuated aerosol dispensing device
US3565070A (en) 1969-02-28 1971-02-23 Riker Laboratories Inc Inhalation actuable aerosol dispenser
US3837573A (en) 1972-03-02 1974-09-24 W Wagner Apparatus for electrified spraying
US3958959A (en) 1972-11-02 1976-05-25 Trw Inc. Method of removing particles and fluids from a gas stream by charged droplets
US3897905A (en) 1973-10-19 1975-08-05 Universal Oil Prod Co Electrostatic spraying nozzle
US3930061A (en) 1974-04-08 1975-12-30 Ransburg Corp Electrostatic method for forming structures and articles
GB1527592A (en) 1974-08-05 1978-10-04 Ici Ltd Wound dressing
JPS5926352B2 (ja) * 1976-02-13 1984-06-26 関西ペイント株式会社 静電粉体塗装方法
CA1109545A (en) * 1976-05-08 1981-09-22 Nissan Motor Co., Ltd. Electrostatic apparatus for controlling flow rate of liquid
DE2724213A1 (de) 1976-05-29 1977-12-15 Nissan Motor Verfahren zum betreiben einer kraftstoff-einspritzeinrichtung
IE45426B1 (en) 1976-07-15 1982-08-25 Ici Ltd Atomisation of liquids
GB1569707A (en) 1976-07-15 1980-06-18 Ici Ltd Atomisation of liquids
US4073002A (en) 1976-11-02 1978-02-07 Ppg Industries, Inc. Self-adjusting power supply for induction charging electrodes
US4255777A (en) * 1977-11-21 1981-03-10 Exxon Research & Engineering Co. Electrostatic atomizing device
GB2018627B (en) 1978-04-17 1982-04-15 Ici Ltd Process and apparatus for spraying liguid
AU531759B2 (en) 1978-04-17 1983-09-08 Ici Ltd. Electrostatic spraying
DE2960875D1 (en) 1978-04-19 1981-12-10 Ici Plc A method of preparing a tubular product by electrostatic spinning
US4198781A (en) * 1978-08-03 1980-04-22 Lasco, Inc. Plant destruction utilizing electrically conductive liquid
US4186886A (en) 1978-08-04 1980-02-05 Ppg Industries, Inc. Adapting means providing detachable mounting of an induction-charging adapter head on a spray device
CY1287A (en) * 1978-09-26 1985-07-05 Ici Plc Electrostatic spraying of liquid
US4266721A (en) 1979-09-17 1981-05-12 Ppg Industries, Inc. Spray application of coating compositions utilizing induction and corona charging means
EP0029301B1 (de) 1979-11-19 1984-12-12 Imperial Chemical Industries Plc Elektrostatischer Sprühapparat
EP0031649B1 (de) * 1979-12-21 1984-09-26 Imperial Chemical Industries Plc Behälter und Behälterträger zur Verwendung beim elektrostatischen Versprühen
DE3036814C2 (de) 1980-09-30 1984-10-04 Fa. Carl Freudenberg, 6940 Weinheim Wundkompresse und Verfahren zu ihrer Herstellung
ATE11232T1 (de) * 1980-11-11 1985-02-15 Imperial Chemical Industries Plc Behaelter zur verwendung beim elektrostatischen zerstaeuben.
DE3042745C2 (de) 1980-11-13 1982-09-30 Philips Patentverwaltung Gmbh, 2000 Hamburg Magnetbandkassettengerät mit mindestens zwei Drucktasten
EP0058472B1 (de) 1981-02-12 1986-04-23 Imperial Chemical Industries Plc Flüssigkeitszerstäuber für landwirtschaftlichen Einsatz sowie dazugehörige Vorratsbehälter
JPS6057907B2 (ja) * 1981-06-18 1985-12-17 工業技術院長 液体の混合噴霧化方法
SU1005939A1 (ru) 1981-06-29 1983-03-23 Уральский научно-исследовательский институт трубной промышленности Устройство дл электростатического напылени порошковых материалов
US4439980A (en) 1981-11-16 1984-04-03 The United States Of America As Represented By The Secretary Of The Navy Electrohydrodynamic (EHD) control of fuel injection in gas turbines
GB2126431B (en) * 1982-08-25 1986-12-03 Ici Plc Pump and pump components
GB2128900B (en) * 1982-10-29 1985-11-20 Theoktiste Christofidis Ionising spray
EP0121288B1 (de) 1983-01-06 1989-05-17 National Research Development Corporation Elektrostatischer Spritzkopf
DE3475598D1 (en) 1983-03-25 1989-01-19 Ici Plc Spraying apparatus
US4509694A (en) 1983-06-01 1985-04-09 Canadian Patents & Development Limited Cross-current airfoil electrostatic nozzle
NZ209210A (en) 1983-08-18 1988-04-29 Ici Plc Electrostatic sprayhead atomises aqueous liquids
US4657793A (en) 1984-07-16 1987-04-14 Ethicon, Inc. Fibrous structures
GB8432272D0 (en) * 1984-12-20 1985-01-30 Ici Plc Spraying apparatus
GB8504254D0 (en) 1985-02-19 1985-03-20 Ici Plc Spraying apparatus
DE216502T1 (de) * 1985-09-03 1987-07-23 Sale Tilney Technology Plc, London, Gb Rakel zum elektrostatischen beschichten und verfahren zum elektrostatischen bespruehen.
US4671289A (en) 1985-11-08 1987-06-09 Renco Corporation Housing for ultrasonic detector
GB8604328D0 (en) 1986-02-21 1986-03-26 Ici Plc Producing spray of droplets of liquid
GB8609703D0 (en) * 1986-04-21 1986-05-29 Ici Plc Electrostatic spraying
GB8614566D0 (en) * 1986-06-16 1986-07-23 Ici Plc Spraying
GB8614564D0 (en) 1986-06-16 1986-07-23 Ici Plc Spraying
US4748043A (en) 1986-08-29 1988-05-31 Minnesota Mining And Manufacturing Company Electrospray coating process
US4749125A (en) 1987-01-16 1988-06-07 Terronics Development Corp. Nozzle method and apparatus
DE3707547A1 (de) * 1987-03-10 1988-09-22 Bayer Ag Verfahren und vorrichtung zum verspritzen von pflanzenschutzmittelloesungen oder -dispersionen
US4779515A (en) 1987-05-15 1988-10-25 General Motors Corporation Vacuum brake booster with bayonet mount having snap-retained mounting arm
DD271611A3 (de) 1987-10-27 1989-09-13 Verkehrswesen Hochschule Spruehpistole mit elektrokinetischer pulveraufladung
US5115971A (en) * 1988-09-23 1992-05-26 Battelle Memorial Institute Nebulizer device
US5267555A (en) 1988-07-01 1993-12-07 Philip Pajalich Apparatus and method for ionizing medication containing mists
DE3925749C1 (de) * 1989-08-03 1990-10-31 Fraunhofer-Gesellschaft Zur Foerderung Der Angewandten Forschung Ev, 8000 Muenchen, De
US5044564A (en) 1989-11-21 1991-09-03 Sickles James E Electrostatic spray gun
DE4022393A1 (de) 1990-07-13 1992-01-23 Marquardt Klaus Ionisator zur ionisierung von sauerstoff bei sauerstoff-therapie
DK0468735T3 (da) 1990-07-25 1995-07-17 Ici Plc Elektrostatisk sprøjtemetode
US5086972A (en) 1990-08-01 1992-02-11 Hughes Aircraft Company Enhanced electrostatic paint deposition method and apparatus
DE4106564C2 (de) 1991-03-01 1999-06-10 Bosch Gmbh Robert Vorrichtung zur elektrostatischen Zerstäubung von Flüssigkeiten
US5196171A (en) 1991-03-11 1993-03-23 In-Vironmental Integrity, Inc. Electrostatic vapor/aerosol/air ion generator
US5282982A (en) 1991-07-12 1994-02-01 Wells John R Blood washing method
GB9115277D0 (en) 1991-07-15 1991-08-28 Unilever Plc Spraying system
GB9115278D0 (en) 1991-07-15 1991-08-28 Unilever Plc Liquid spraying apparatus and method
GB9115279D0 (en) 1991-07-15 1991-08-28 Unilever Plc Hair and scalp treatment system
GB9219636D0 (en) 1991-10-10 1992-10-28 Ici Plc Spraying of liquids
WO1994013266A1 (en) 1992-05-29 1994-06-23 The Regents Of The University Of California Novel electrostatic process for manufacturing coated transplants and products
GB9225098D0 (en) * 1992-12-01 1993-01-20 Coffee Ronald A Charged droplet spray mixer
GB9226717D0 (en) 1992-12-22 1993-02-17 Coffee Ronald A Induction-operated electro-hydrodynamic spray device with means of modifying droplet trajectories
US5402945A (en) * 1993-01-22 1995-04-04 Gervan Company International Method for spraying plants and apparatus for its practice
US5409162A (en) 1993-08-09 1995-04-25 Sickles; James E. Induction spray charging apparatus
GB9406171D0 (en) * 1994-03-29 1994-05-18 Electrosols Ltd Dispensing device
GB9406255D0 (en) 1994-03-29 1994-05-18 Electrosols Ltd Dispensing device
GB9410658D0 (en) 1994-05-27 1994-07-13 Electrosols Ltd Dispensing device
US5483953A (en) 1995-04-08 1996-01-16 The United States Of America As Represented By The Secretary Of The Navy Aerosol dispensing apparatus for dispensing a medicated vapor into the lungs of a patient
GB2327895B (en) 1997-08-08 2001-08-08 Electrosols Ltd A dispensing device

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NZ258174A (en) 1997-03-24
EP0671980B1 (de) 1999-04-14
CA2150692A1 (en) 1994-06-09
EP0671980A1 (de) 1995-09-20
AU685411B2 (en) 1998-01-22
HK1012301A1 (en) 1999-07-30
DK0671980T3 (da) 1999-10-25
WO1994012285A2 (en) 1994-06-09
CA2150692C (en) 2006-09-05
AU718118B2 (en) 2000-04-06
WO1994012285A3 (en) 1994-10-13
US6105877A (en) 2000-08-22
ATE178814T1 (de) 1999-04-15
GR3030735T3 (en) 1999-11-30
TW242576B (de) 1995-03-11
US6318640B1 (en) 2001-11-20
AU5570294A (en) 1994-06-22
JPH08504126A (ja) 1996-05-07
KR100289783B1 (ko) 2001-09-17
AU6351398A (en) 1998-07-02
ES2130393T3 (es) 1999-07-01
MX9307490A (es) 1994-08-31
DE69324499T2 (de) 1999-08-12
NZ314209A (en) 1998-02-26
CN1090208A (zh) 1994-08-03
ZA938895B (en) 1995-03-31
GB9225098D0 (en) 1993-01-20
CN1104262C (zh) 2003-04-02

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