DE69324499D1 - Austragevorrichtung - Google Patents

Austragevorrichtung

Info

Publication number
DE69324499D1
DE69324499D1 DE69324499T DE69324499T DE69324499D1 DE 69324499 D1 DE69324499 D1 DE 69324499D1 DE 69324499 T DE69324499 T DE 69324499T DE 69324499 T DE69324499 T DE 69324499T DE 69324499 D1 DE69324499 D1 DE 69324499D1
Authority
DE
Germany
Prior art keywords
delivery
respiratory tract
liquids
discharge device
droplets
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69324499T
Other languages
English (en)
Other versions
DE69324499T2 (de
Inventor
Ronald Alan Coffee
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Battelle Memorial Institute Inc
Original Assignee
Electrosols Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Electrosols Ltd filed Critical Electrosols Ltd
Publication of DE69324499D1 publication Critical patent/DE69324499D1/de
Application granted granted Critical
Publication of DE69324499T2 publication Critical patent/DE69324499T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B5/00—Electrostatic spraying apparatus; Spraying apparatus with means for charging the spray electrically; Apparatus for spraying liquids or other fluent materials by other electric means
    • B05B5/002—Electrostatic spraying apparatus; Spraying apparatus with means for charging the spray electrically; Apparatus for spraying liquids or other fluent materials by other electric means comprising means for neutralising the spray of charged droplets or particules
    • B05B5/003—Electrostatic spraying apparatus; Spraying apparatus with means for charging the spray electrically; Apparatus for spraying liquids or other fluent materials by other electric means comprising means for neutralising the spray of charged droplets or particules by mixing two sprays of opposite polarity
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/02—Inhalators with activated or ionised fluids, e.g. electrohydrodynamic [EHD] or electrostatic devices; Ozone-inhalators with radioactive tagged particles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B5/00—Electrostatic spraying apparatus; Spraying apparatus with means for charging the spray electrically; Apparatus for spraying liquids or other fluent materials by other electric means
    • B05B5/025—Discharge apparatus, e.g. electrostatic spray guns
    • B05B5/0255—Discharge apparatus, e.g. electrostatic spray guns spraying and depositing by electrostatic forces only
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B5/00—Electrostatic spraying apparatus; Spraying apparatus with means for charging the spray electrically; Apparatus for spraying liquids or other fluent materials by other electric means
    • B05B5/025—Discharge apparatus, e.g. electrostatic spray guns
    • B05B5/053—Arrangements for supplying power, e.g. charging power
    • B05B5/0531—Power generators
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B5/00—Electrostatic spraying apparatus; Spraying apparatus with means for charging the spray electrically; Apparatus for spraying liquids or other fluent materials by other electric means
    • B05B5/16—Arrangements for supplying liquids or other fluent material
DE69324499T 1992-12-01 1993-11-26 Austragevorrichtung Expired - Lifetime DE69324499T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB929225098A GB9225098D0 (en) 1992-12-01 1992-12-01 Charged droplet spray mixer
PCT/GB1993/002443 WO1994012285A2 (en) 1992-12-01 1993-11-26 Dispensing device

Publications (2)

Publication Number Publication Date
DE69324499D1 true DE69324499D1 (de) 1999-05-20
DE69324499T2 DE69324499T2 (de) 1999-08-12

Family

ID=10725936

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69324499T Expired - Lifetime DE69324499T2 (de) 1992-12-01 1993-11-26 Austragevorrichtung

Country Status (19)

Country Link
US (2) US6105877A (de)
EP (1) EP0671980B1 (de)
JP (1) JPH08504126A (de)
KR (1) KR100289783B1 (de)
CN (1) CN1104262C (de)
AT (1) ATE178814T1 (de)
AU (1) AU685411B2 (de)
CA (1) CA2150692C (de)
DE (1) DE69324499T2 (de)
DK (1) DK0671980T3 (de)
ES (1) ES2130393T3 (de)
GB (1) GB9225098D0 (de)
GR (1) GR3030735T3 (de)
HK (1) HK1012301A1 (de)
MX (1) MX9307490A (de)
NZ (2) NZ314209A (de)
TW (1) TW242576B (de)
WO (1) WO1994012285A2 (de)
ZA (1) ZA938895B (de)

Families Citing this family (156)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9225098D0 (en) 1992-12-01 1993-01-20 Coffee Ronald A Charged droplet spray mixer
US6105571A (en) 1992-12-22 2000-08-22 Electrosols, Ltd. Dispensing device
GB9410658D0 (en) * 1994-05-27 1994-07-13 Electrosols Ltd Dispensing device
US5758637A (en) 1995-08-31 1998-06-02 Aerogen, Inc. Liquid dispensing apparatus and methods
US5863497A (en) * 1996-03-11 1999-01-26 The Proctor & Gamble Company Electrostatic hand sanitizer
EP0963181A1 (de) * 1996-03-11 1999-12-15 The Procter & Gamble Company Elektrostatisches desinfektionsgerät für hände
US6252129B1 (en) 1996-07-23 2001-06-26 Electrosols, Ltd. Dispensing device and method for forming material
US20080119772A1 (en) 2001-01-11 2008-05-22 Ronald Alan Coffee Dispensing device and method for forming material
WO1998003267A1 (en) 1996-07-23 1998-01-29 Electrosols Ltd. A dispensing device and method for forming material
US6433154B1 (en) 1997-06-12 2002-08-13 Bristol-Myers Squibb Company Functional receptor/kinase chimera in yeast cells
GB2327895B (en) 1997-08-08 2001-08-08 Electrosols Ltd A dispensing device
CN1154007C (zh) * 1997-10-27 2004-06-16 积水化学株学会社 喷射微粒的设备及其使用方法和制造液晶显示器的方法
JP3681561B2 (ja) * 1997-12-26 2005-08-10 日本碍子株式会社 物質の均一混合方法及び混合装置
SE512386C2 (sv) * 1998-07-30 2000-03-06 Microdrug Ag Förfarande och anordning för klassificering av elektrostatiskt laddat pulverformigt material
GB2345010B (en) * 1998-12-17 2002-12-31 Electrosols Ltd A delivery device
US20040116032A1 (en) * 1999-02-25 2004-06-17 Bowlin Gary L. Electroprocessed collagen
US6592623B1 (en) 1999-08-31 2003-07-15 Virginia Commonwealth University Intellectual Property Foundation Engineered muscle
US7615373B2 (en) * 1999-02-25 2009-11-10 Virginia Commonwealth University Intellectual Property Foundation Electroprocessed collagen and tissue engineering
US20020081732A1 (en) * 2000-10-18 2002-06-27 Bowlin Gary L. Electroprocessing in drug delivery and cell encapsulation
ATE313384T1 (de) * 1999-04-23 2006-01-15 Battelle Memorial Institute Richtungsverstellbarer ehd- aerosol-zerstäuber
US6495015B1 (en) * 1999-06-18 2002-12-17 Sandia National Corporation Electrokinetically pumped high pressure sprays
US6235177B1 (en) 1999-09-09 2001-05-22 Aerogen, Inc. Method for the construction of an aperture plate for dispensing liquid droplets
DE60138535D1 (de) * 2000-02-04 2009-06-10 Children S Hospital Res Founda Verwendung von lysosomal acid lipase zur behandlung von atherosklerose und ähnlichen krankheiten
WO2001074431A2 (en) * 2000-04-03 2001-10-11 Battelle Memorial Institute Dispensing devices and liquid formulations
US7971588B2 (en) 2000-05-05 2011-07-05 Novartis Ag Methods and systems for operating an aerosol generator
US8336545B2 (en) 2000-05-05 2012-12-25 Novartis Pharma Ag Methods and systems for operating an aerosol generator
CN1247314C (zh) 2000-05-16 2006-03-29 明尼苏达大学评议会 电喷射方法和设备
US6339107B1 (en) 2000-08-02 2002-01-15 Syntex (U.S.A.) Llc Methods for treatment of Emphysema using 13-cis retinoic acid
EP1315756A2 (de) * 2000-09-01 2003-06-04 Virginia Commonwealth University Intellectual Property Foundation Elektroplattierte fibrin-basierte träger und gewebe
EP1935869A1 (de) 2000-10-02 2008-06-25 F. Hoffmann-La Roche Ag Retinoide zur Behandlung von Emphysem
AU3664102A (en) 2000-12-01 2002-06-11 Battelle Memorial Institute Method for stabilizing biomolecules in liquid formulations
US7674429B2 (en) * 2001-01-22 2010-03-09 Johnsondiversey, Inc. Electrostatic disinfectant delivery
US6546927B2 (en) * 2001-03-13 2003-04-15 Aerogen, Inc. Methods and apparatus for controlling piezoelectric vibration
JP2005501810A (ja) 2001-03-22 2005-01-20 バテル メモリアル インスティチュート ポリマーおよび懸濁粒子を含有する電気流体力学的噴霧用の液体形成物
US7247338B2 (en) * 2001-05-16 2007-07-24 Regents Of The University Of Minnesota Coating medical devices
CN1236831C (zh) * 2001-05-21 2006-01-18 茵捷特数码浮质有限公司 用于经肺部途径递送蛋白质的组合物
EP1273346A1 (de) * 2001-07-05 2003-01-08 Seyonic SA Mehrkanalige Vorrichtung zum Abgeben von Fluiden
US20030017359A1 (en) * 2001-07-17 2003-01-23 American Air Liquide, Inc. Increased stability low concentration gases, products comprising same, and methods of making same
US7832550B2 (en) 2001-07-17 2010-11-16 American Air Liquide, Inc. Reactive gases with concentrations of increased stability and processes for manufacturing same
CN1223701C (zh) 2001-07-17 2005-10-19 液体空气乔治洛德方法利用和研究的具有监督和管理委员会的有限公司 高稳定性低浓度气体,含有它的产品及其制备方法
WO2003057291A1 (en) 2002-01-07 2003-07-17 Aerogen, Inc. Devices and methods for nebulizing fluids for inhalation
US7677467B2 (en) 2002-01-07 2010-03-16 Novartis Pharma Ag Methods and devices for aerosolizing medicament
EP1474196B1 (de) 2002-01-15 2016-08-17 Novartis AG Verfahren und systeme zum bedienen eines aerosol-erzeugers
AU2002234776A1 (en) * 2002-03-01 2003-09-16 Unilever Plc Electrostatic spraying of a cosmetic composition
AU2003256253A1 (en) 2002-05-20 2003-12-02 Aerogen, Inc. Aerosol for medical treatment and methods
KR100923941B1 (ko) * 2002-05-29 2009-10-29 레르 리키드 쏘시에떼 아노님 뿌르 레드 에렉스뿔라따시옹 데 프로세데 조르즈 클로드 산 기체 및 매트릭스 기체를 포함하는 수분 감소된 조성물, 상기 조성물을 포함하는 제품 및 이의 제조 방법
DE10228280A1 (de) * 2002-06-25 2004-01-29 Institut für Chemo- und Biosensorik Münster e.V. i.Ins. Vorrichtung und Verfahren zur Beschichtung dreidimensional strukturierter Oberflächen von Substraten
US20060179491A1 (en) * 2002-11-12 2006-08-10 Brian Graham Process for treating non-human animals
ZA200504940B (en) 2003-01-28 2006-09-27 Xenoport Inc Amino acid derived prodrugs of propofol, compositions and uses thereof
US7849850B2 (en) * 2003-02-28 2010-12-14 Battelle Memorial Institute Nozzle for handheld pulmonary aerosol delivery device
ES2436606T3 (es) 2003-03-12 2014-01-03 Celgene Corporation Compuestos de 7-amido-isoindolilo y sus usos farmacéuticos
EP1462801A3 (de) * 2003-03-24 2005-01-05 Tepnel Lifecodes Methoden zur messung der negativkontrolle in mehrfachanalyt-assays
GB0307403D0 (en) 2003-03-31 2003-05-07 Medical Res Council Selection by compartmentalised screening
US20060078893A1 (en) 2004-10-12 2006-04-13 Medical Research Council Compartmentalised combinatorial chemistry by microfluidic control
GB0307428D0 (en) 2003-03-31 2003-05-07 Medical Res Council Compartmentalised combinatorial chemistry
GB0308021D0 (en) * 2003-04-07 2003-05-14 Aerstream Technology Ltd Spray electrode
EP4101846B1 (de) 2003-04-11 2023-08-02 PTC Therapeutics, Inc. 1,2,4-oxadiazolbenzoesäureverbindungen und deren verwendung zur nonsense-unterdrückung und behandlung von krankheiten
US8616195B2 (en) 2003-07-18 2013-12-31 Novartis Ag Nebuliser for the production of aerosolized medication
DE10334591B4 (de) * 2003-07-28 2006-03-30 International Flavors & Fragrances Inc. Verfahren zum Verteilen von flüssigen Duftstoffen und Vorrichtung zur Durchführung des Verfahrens
WO2005023204A2 (en) 2003-09-09 2005-03-17 Xenoport, Inc. Aromatic prodrugs of propofol, compositions and uses thereof
DE10344135A1 (de) * 2003-09-24 2005-05-04 Karlsruhe Forschzent Vorrichtung zum Aufbringen von Elektrospraybeschichtungen auf elektrisch nicht leitfähigen Oberflächen
US20050079113A1 (en) * 2003-10-09 2005-04-14 Selander Raymond K. Fan-driven air freshener
DE10349472B4 (de) * 2003-10-21 2006-01-19 Forschungszentrum Karlsruhe Gmbh Beschichtungsvorrichtung für Polymere
WO2005051942A1 (en) 2003-11-19 2005-06-09 Signal Pharmaceuticals, Llc Indazole compounds and methods of use thereof as protein kinase inhibitors
NL1025556C1 (nl) * 2004-02-24 2005-08-26 Jacob Korevaar Inrichting en werkwijze voor het toedienen van een fluïdum aan een mens of zoogdier.
US20050221339A1 (en) 2004-03-31 2005-10-06 Medical Research Council Harvard University Compartmentalised screening by microfluidic control
US7946291B2 (en) 2004-04-20 2011-05-24 Novartis Ag Ventilation systems and methods employing aerosol generators
DK1781596T3 (da) 2004-07-12 2009-01-19 Xenoport Inc Aminosyreafledte profarmaka af propofolsammensætninger og anvendelser deraf
WO2006017351A1 (en) 2004-07-12 2006-02-16 Xenoport, Inc. Prodrugs of propofol, compositions and uses thereof
EP1799197A2 (de) 2004-09-14 2007-06-27 Battelle Memorial Institute Hochwässrige nichteinatembare aerosole mit biologisch wirksamen inhaltsstoffen; herstellungsverfahren und vorrichtung dafür
US7968287B2 (en) 2004-10-08 2011-06-28 Medical Research Council Harvard University In vitro evolution in microfluidic systems
US7360724B2 (en) 2004-10-20 2008-04-22 The Procter & Gamble Company Electrostatic spray nozzle with internal and external electrodes
DK2561872T3 (en) 2004-12-17 2014-12-08 Anadys Pharmaceuticals Inc 3,5-DISUBSTITUTED AND 3,5,7-TRISUBSTITUTED 3H-OXAZOLO- [4,5-d] PYRIMIDIN-2-ON COMPOUNDS AND PRODRUGS THEREOF
FR2879482B1 (fr) * 2004-12-20 2007-03-30 Oreal Dispositif de pulverisation d'un produit, notamment d'un parfum
WO2006071995A1 (en) 2004-12-23 2006-07-06 Xenoport, Inc. Serine amino acid derived prodrugs of propofol, compositions, uses and crystalline forms thereof
WO2006086655A1 (en) * 2005-02-11 2006-08-17 Battelle Memorial Institute Ehd aerosol dispensing device and spraying method
WO2006091790A1 (en) 2005-02-23 2006-08-31 Xenoport, Inc. Platinum-containing compounds exhibiting cytostatic activity, synthesis and methods of use
DE102005016829A1 (de) 2005-04-12 2006-11-02 Iff International Flavors & Fragrances Verfahren, Düse und Vorrichtung zur Zerstäubung von in einer Flüssigkeit enthaltenen Wirkstoffen
CN101208123B (zh) 2005-05-25 2012-09-19 亚罗擎公司 振动系统和方法
EP1928881A2 (de) 2005-08-19 2008-06-11 Pharmacofore, Inc. Prodrugs von wirkstoffen
WO2007030375A2 (en) * 2005-09-08 2007-03-15 Children's Hospital Medical Center Lysosomal acid lipase therapy for nafld and related diseases
GB0524979D0 (en) 2005-12-07 2006-01-18 Queen Mary & Westfield College An electrospray device and a method of electrospraying
WO2007081385A2 (en) 2006-01-11 2007-07-19 Raindance Technologies, Inc. Microfluidic devices and methods of use in the formation and control of nanoreactors
EP2529761B1 (de) 2006-01-31 2017-06-14 Nanocopoeia, Inc. Oberflächenbeschichtung mit nanoteilchen
US7951428B2 (en) * 2006-01-31 2011-05-31 Regents Of The University Of Minnesota Electrospray coating of objects
US9108217B2 (en) 2006-01-31 2015-08-18 Nanocopoeia, Inc. Nanoparticle coating of surfaces
EP2018224B1 (de) 2006-02-14 2019-03-06 EField Innovations LLC Ehd-zerstäuber mit getrennter entladung und schutz vor elektrischem feld
JP2009530390A (ja) 2006-03-23 2009-08-27 アムゲン インコーポレイティッド １−フェニルスルホニル−ジアザ複素環アミド化合物およびヒドロキシステロイドデヒドロゲナーゼ調節因子としてのその使用
DE102006017002B3 (de) * 2006-04-11 2007-01-11 Pari GmbH Spezialisten für effektive Inhalation Inhalationstherapievorrichtung mit mehrfachen Düsen
US9074242B2 (en) 2010-02-12 2015-07-07 Raindance Technologies, Inc. Digital analyte analysis
EP2530168B1 (de) 2006-05-11 2015-09-16 Raindance Technologies, Inc. Mikrofluidische Vorrichtungen
US9562837B2 (en) 2006-05-11 2017-02-07 Raindance Technologies, Inc. Systems for handling microfludic droplets
EP2402037B8 (de) 2006-05-26 2019-12-04 Signature Therapeutics, Inc. Kontrollierte Freisetzung phenolischer Opioide
CA2654699A1 (en) 2006-06-08 2007-12-21 Amgen Inc. Benzamide derivatives and uses related thereto
TW200808695A (en) 2006-06-08 2008-02-16 Amgen Inc Benzamide derivatives and uses related thereto
US7673819B2 (en) * 2006-06-26 2010-03-09 Battelle Memorial Institute Handheld sprayer with removable cartridge and method of using same
US7709448B2 (en) 2006-06-22 2010-05-04 Anadys Pharmaceuticals, Inc. Prodrugs of 5-amino-3-(3′-deoxy-β-D-ribofuranosyl)-thiazolo[4,5-d]pyrimidin-2,7-dione
WO2007150001A1 (en) 2006-06-22 2007-12-27 Anadys Pharmaceuticals, Inc. Pyrro[1,2-b]pyridazinone compounds
WO2008002556A1 (en) * 2006-06-26 2008-01-03 Battelle Memorial Institute Cartridge having self-actuating seal for a wetted lead screw
BRPI0714831A2 (pt) 2006-07-18 2013-04-02 Anadys Pharmaceuticals Inc composto, composiÇço farmacÊutica e mÉtodos de modulaÇço de atividades imuno da citoquina em paciente, de tratamento de infecÇço de vÍrus c da hepatite em paciente e de desordem relacionada com proliferaÇço em mamÍfero necessitado do mesmo
EP2051977A2 (de) 2006-07-20 2009-04-29 Amgen Inc. SUBSTITUIERTE AROMATISCHE AZOL-HETEROCYCLEN ALS LLbeta-HSD-1-HEMMER
US9012390B2 (en) 2006-08-07 2015-04-21 Raindance Technologies, Inc. Fluorocarbon emulsion stabilizing surfactants
US9040816B2 (en) * 2006-12-08 2015-05-26 Nanocopoeia, Inc. Methods and apparatus for forming photovoltaic cells using electrospray
FR2910253B1 (fr) * 2006-12-20 2010-03-12 Oreal Procede de distribution d'un produit pulverise par un systeme de pulverisation piezoelectrique et systeme de pulverisation pour la mise en oeuvre d'un tel procede
FR2910254B1 (fr) * 2006-12-20 2009-04-17 Oreal Systeme de pulverisation piezoelectrique et recharge correspondante
US7932421B2 (en) 2006-12-26 2011-04-26 Amgen Inc. N-cyclohexyl benzamides and benzeneacetamides as inhibitors of 11-beta-hydroxysteroid dehydrogenases
EP2111305A2 (de) * 2007-01-31 2009-10-28 Nanocopoeia, Inc. Oberflächenbeschichtung mit nanoteilchen
US8772046B2 (en) 2007-02-06 2014-07-08 Brandeis University Manipulation of fluids and reactions in microfluidic systems
US8592221B2 (en) 2007-04-19 2013-11-26 Brandeis University Manipulation of fluids, fluid components and reactions in microfluidic systems
US20080269665A1 (en) * 2007-04-24 2008-10-30 Johan Petersen Chemotherapy delivery device
GB0709517D0 (en) * 2007-05-17 2007-06-27 Queen Mary & Westfield College An electrostatic spraying device and a method of electrostatic spraying
EP4047367A1 (de) 2008-07-18 2022-08-24 Bio-Rad Laboratories, Inc. Verfahren zum nachweis von zielanalyten unter verwendung von tropfenbibliotheken
TWI480272B (zh) 2008-10-09 2015-04-11 Anadys Pharmaceuticals Inc 藉由５，６－二氫－１ｈ－吡啶－２－酮與一或多種其他抗病毒化合物的組合物抑制ｃ型肝炎病毒的方法
ITRM20090039A1 (it) * 2009-01-29 2010-07-30 Uni Degli Studi Di Roma To R Vergata Sistema di dispersione di micro o nanoparticelle solide in una fase liquida
GB0903134D0 (en) * 2009-02-24 2009-04-08 Osmotex Ag Charged particle motion inducing apparatus
EP3415235A1 (de) 2009-03-23 2018-12-19 Raindance Technologies Inc. Manipulation von mikrofluidiktröpfchen
WO2011042564A1 (en) 2009-10-09 2011-04-14 Universite De Strasbourg Labelled silica-based nanomaterial with enhanced properties and uses thereof
EP2517025B1 (de) 2009-12-23 2019-11-27 Bio-Rad Laboratories, Inc. Verfahren zur reduzierung des austauschs von molekülen zwischen tröpfchen
US20110174304A1 (en) * 2010-01-21 2011-07-21 Triplett Ii Michael D Electrohydrodynamic aerosolization device having a time varying voltage
US9366632B2 (en) 2010-02-12 2016-06-14 Raindance Technologies, Inc. Digital analyte analysis
US10351905B2 (en) 2010-02-12 2019-07-16 Bio-Rad Laboratories, Inc. Digital analyte analysis
US9399797B2 (en) 2010-02-12 2016-07-26 Raindance Technologies, Inc. Digital analyte analysis
JP5429993B2 (ja) * 2010-03-04 2014-02-26 国立大学法人東京工業大学 匂い発生装置
WO2011133516A1 (en) * 2010-04-19 2011-10-27 Battelle Memorial Institute Electrohydrodynamic spraying
WO2012045012A2 (en) 2010-09-30 2012-04-05 Raindance Technologies, Inc. Sandwich assays in droplets
EP3412778A1 (de) 2011-02-11 2018-12-12 Raindance Technologies, Inc. Verfahren zur bildung gemischter tröpfchen
WO2012112804A1 (en) 2011-02-18 2012-08-23 Raindance Technoligies, Inc. Compositions and methods for molecular labeling
WO2012158271A1 (en) 2011-04-06 2012-11-22 Anadys Pharmaceuticals, Inc. Bridged polycyclic compounds as antiviral agents
WO2012167142A2 (en) 2011-06-02 2012-12-06 Raindance Technolgies, Inc. Enzyme quantification
US8841071B2 (en) 2011-06-02 2014-09-23 Raindance Technologies, Inc. Sample multiplexing
JP5892708B2 (ja) * 2011-06-16 2016-03-23 国立研究開発法人産業技術総合研究所 エレクトロスプレーによるマイクロ反応場形成装置及び化学反応制御方法
US8658430B2 (en) 2011-07-20 2014-02-25 Raindance Technologies, Inc. Manipulating droplet size
JP5762872B2 (ja) * 2011-07-29 2015-08-12 住友化学株式会社 静電噴霧装置
US10350409B2 (en) 2013-03-15 2019-07-16 Ottfried Waldenburg Instrument for and method of treating venomous bites
US20150053786A1 (en) * 2013-08-21 2015-02-26 Trimble Navigation Limited Intelligent precision irrigation system
US11901041B2 (en) 2013-10-04 2024-02-13 Bio-Rad Laboratories, Inc. Digital analysis of nucleic acid modification
US9944977B2 (en) 2013-12-12 2018-04-17 Raindance Technologies, Inc. Distinguishing rare variations in a nucleic acid sequence from a sample
EP3090063B1 (de) 2013-12-31 2019-11-06 Bio-Rad Laboratories, Inc. Verfahren zur detektion von latentem retrovirus
CN104138630B (zh) * 2014-07-30 2017-05-10 北京银河之舟科技有限公司 一种呼吸道给药的装置及方法
JP6083031B2 (ja) * 2015-05-15 2017-02-22 国立研究開発法人産業技術総合研究所 液中エレクトロスプレー法及び液中エレクトロスプレー装置
US10647981B1 (en) 2015-09-08 2020-05-12 Bio-Rad Laboratories, Inc. Nucleic acid library generation methods and compositions
US10335406B2 (en) 2015-10-01 2019-07-02 Elysium Therapeutics, Inc. Opioid compositions resistant to overdose and abuse
GB2556817B (en) 2015-10-01 2019-11-06 Elysium Therapeutics Inc Polysubunit opioid prodrugs resistant to overdose and abuse
US20170095834A1 (en) * 2015-10-05 2017-04-06 William Brian Kinard Electrostatic deposition
US10455863B2 (en) 2016-03-03 2019-10-29 Altria Client Services Llc Cartridge for electronic vaping device
US10433580B2 (en) 2016-03-03 2019-10-08 Altria Client Services Llc Methods to add menthol, botanic materials, and/or non-botanic materials to a cartridge, and/or an electronic vaping device including the cartridge
US10368580B2 (en) 2016-03-08 2019-08-06 Altria Client Services Llc Combined cartridge for electronic vaping device
US10368581B2 (en) 2016-03-11 2019-08-06 Altria Client Services Llc Multiple dispersion generator e-vaping device
US10357060B2 (en) 2016-03-11 2019-07-23 Altria Client Services Llc E-vaping device cartridge holder
EP3595663A4 (de) 2017-03-17 2021-01-13 Elysium Therapeutics, Inc. Mehrfachuntereinheit-opioid-prodrugs mit resistenz gegen überdosierung und missbrauch
JP2021521280A (ja) 2018-04-12 2021-08-26 マトルクス セラピューティクス コーポレーション 弾性線維分解を治療するための組成物及び方法
CN109037023B (zh) * 2018-06-06 2020-03-10 清华大学深圳研究生院 一种用于产生中性喷雾的装置、方法和物质检测设备
WO2020080347A1 (ja) * 2018-10-17 2020-04-23 住友化学株式会社 静電噴霧装置
CN110755699A (zh) * 2019-09-18 2020-02-07 浙江省北大信息技术高等研究院 可植入的电渗微泵装置
CN111388018B (zh) * 2020-03-20 2023-09-19 威图姆卡医疗中心 采集下呼吸道样本的方法及其装置、空气消毒方法及其装置
GB2598964A (en) * 2020-09-22 2022-03-23 Brian King Andrew Methods and apparatus for inducing chemical reactions using electro-statics

Family Cites Families (79)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2723646A (en) * 1950-04-01 1955-11-15 Ransburg Electro Coating Corp Apparatus for electrostatic atomization and coating
US2945443A (en) * 1957-08-22 1960-07-19 Gen Electric Pump operation
US3096762A (en) 1962-02-12 1963-07-09 Waterbury Pressed Metal Co Oral breathing device
US3131131A (en) * 1962-04-03 1964-04-28 Socony Mobil Oil Co Inc Electrostatic mixing in microbial conversions
US3232292A (en) 1962-10-12 1966-02-01 Arizona Nucleonics Inc Ionized aerosols
US3456646A (en) 1967-01-19 1969-07-22 Dart Ind Inc Inhalation-actuated aerosol dispensing device
US3565070A (en) 1969-02-28 1971-02-23 Riker Laboratories Inc Inhalation actuable aerosol dispenser
US3837573A (en) 1972-03-02 1974-09-24 W Wagner Apparatus for electrified spraying
US3958959A (en) 1972-11-02 1976-05-25 Trw Inc. Method of removing particles and fluids from a gas stream by charged droplets
US3897905A (en) 1973-10-19 1975-08-05 Universal Oil Prod Co Electrostatic spraying nozzle
US3930061A (en) 1974-04-08 1975-12-30 Ransburg Corp Electrostatic method for forming structures and articles
GB1527592A (en) 1974-08-05 1978-10-04 Ici Ltd Wound dressing
JPS5926352B2 (ja) * 1976-02-13 1984-06-26 関西ペイント株式会社 静電粉体塗装方法
CA1109545A (en) 1976-05-08 1981-09-22 Nissan Motor Co., Ltd. Electrostatic apparatus for controlling flow rate of liquid
US4150644A (en) 1976-05-29 1979-04-24 Nissan Motor Company, Limited Method for controlling electrostatic fuel injectors
GB1569707A (en) 1976-07-15 1980-06-18 Ici Ltd Atomisation of liquids
IE45426B1 (en) 1976-07-15 1982-08-25 Ici Ltd Atomisation of liquids
US4073002A (en) 1976-11-02 1978-02-07 Ppg Industries, Inc. Self-adjusting power supply for induction charging electrodes
US4255777A (en) * 1977-11-21 1981-03-10 Exxon Research & Engineering Co. Electrostatic atomizing device
GB2018627B (en) 1978-04-17 1982-04-15 Ici Ltd Process and apparatus for spraying liguid
AU531759B2 (en) 1978-04-17 1983-09-08 Ici Ltd. Electrostatic spraying
EP0005035B1 (de) 1978-04-19 1981-09-23 Imperial Chemical Industries Plc Verfahren zur Herstellung eines Rohrprodukts durch elektrostatisches Spinnen
US4198781A (en) * 1978-08-03 1980-04-22 Lasco, Inc. Plant destruction utilizing electrically conductive liquid
US4186886A (en) 1978-08-04 1980-02-05 Ppg Industries, Inc. Adapting means providing detachable mounting of an induction-charging adapter head on a spray device
GB2030060B (en) * 1978-09-26 1982-12-01 Ici Ltd Electrostatic spraying of liquid
US4266721A (en) 1979-09-17 1981-05-12 Ppg Industries, Inc. Spray application of coating compositions utilizing induction and corona charging means
DE3069807D1 (en) 1979-11-19 1985-01-24 Ici Plc Electrostatic spraying apparatus
DE3069312D1 (en) * 1979-12-21 1984-10-31 Ici Plc Containers and holders therefor for use in electrostatic spraying
DE3036814C2 (de) 1980-09-30 1984-10-04 Fa. Carl Freudenberg, 6940 Weinheim Wundkompresse und Verfahren zu ihrer Herstellung
ATE11232T1 (de) * 1980-11-11 1985-02-15 Imperial Chemical Industries Plc Behaelter zur verwendung beim elektrostatischen zerstaeuben.
DE3042745C2 (de) 1980-11-13 1982-09-30 Philips Patentverwaltung Gmbh, 2000 Hamburg Magnetbandkassettengerät mit mindestens zwei Drucktasten
DE3270700D1 (en) 1981-02-12 1986-05-28 Ici Plc Agricultural spraying apparatus and containers for use therewith
JPS6057907B2 (ja) * 1981-06-18 1985-12-17 工業技術院長 液体の混合噴霧化方法
SU1005939A1 (ru) 1981-06-29 1983-03-23 Уральский научно-исследовательский институт трубной промышленности Устройство дл электростатического напылени порошковых материалов
US4439980A (en) 1981-11-16 1984-04-03 The United States Of America As Represented By The Secretary Of The Navy Electrohydrodynamic (EHD) control of fuel injection in gas turbines
GB2126431B (en) * 1982-08-25 1986-12-03 Ici Plc Pump and pump components
GB2128900B (en) * 1982-10-29 1985-11-20 Theoktiste Christofidis Ionising spray
EP0121288B1 (de) 1983-01-06 1989-05-17 National Research Development Corporation Elektrostatischer Spritzkopf
DE3475598D1 (en) 1983-03-25 1989-01-19 Ici Plc Spraying apparatus
US4509694A (en) 1983-06-01 1985-04-09 Canadian Patents & Development Limited Cross-current airfoil electrostatic nozzle
EP0152446B1 (de) 1983-08-18 1988-12-21 Imperial Chemical Industries Plc Elektrostatisches zerstäubungsverfahren und vorrichtung zu dessen durchführung
US4657793A (en) 1984-07-16 1987-04-14 Ethicon, Inc. Fibrous structures
GB8432272D0 (en) * 1984-12-20 1985-01-30 Ici Plc Spraying apparatus
GB8504254D0 (en) 1985-02-19 1985-03-20 Ici Plc Spraying apparatus
DE3661121D1 (en) * 1985-09-03 1988-12-15 Sale Tilney Technology Plc Electrostatic coating blade and method of electrostatic spraying
US4671289A (en) 1985-11-08 1987-06-09 Renco Corporation Housing for ultrasonic detector
GB8604328D0 (en) * 1986-02-21 1986-03-26 Ici Plc Producing spray of droplets of liquid
GB8609703D0 (en) * 1986-04-21 1986-05-29 Ici Plc Electrostatic spraying
GB8614566D0 (en) * 1986-06-16 1986-07-23 Ici Plc Spraying
GB8614564D0 (en) 1986-06-16 1986-07-23 Ici Plc Spraying
US4748043A (en) 1986-08-29 1988-05-31 Minnesota Mining And Manufacturing Company Electrospray coating process
US4749125A (en) 1987-01-16 1988-06-07 Terronics Development Corp. Nozzle method and apparatus
DE3707547A1 (de) * 1987-03-10 1988-09-22 Bayer Ag Verfahren und vorrichtung zum verspritzen von pflanzenschutzmittelloesungen oder -dispersionen
US4779515A (en) 1987-05-15 1988-10-25 General Motors Corporation Vacuum brake booster with bayonet mount having snap-retained mounting arm
DD271611A3 (de) 1987-10-27 1989-09-13 Verkehrswesen Hochschule Spruehpistole mit elektrokinetischer pulveraufladung
US5115971A (en) * 1988-09-23 1992-05-26 Battelle Memorial Institute Nebulizer device
US5267555A (en) 1988-07-01 1993-12-07 Philip Pajalich Apparatus and method for ionizing medication containing mists
DE3925749C1 (de) * 1989-08-03 1990-10-31 Fraunhofer-Gesellschaft Zur Foerderung Der Angewandten Forschung Ev, 8000 Muenchen, De
US5044564A (en) 1989-11-21 1991-09-03 Sickles James E Electrostatic spray gun
DE4022393A1 (de) 1990-07-13 1992-01-23 Marquardt Klaus Ionisator zur ionisierung von sauerstoff bei sauerstoff-therapie
ATE121970T1 (de) 1990-07-25 1995-05-15 Ici Plc Elektrostatische sprühmethode.
US5086972A (en) 1990-08-01 1992-02-11 Hughes Aircraft Company Enhanced electrostatic paint deposition method and apparatus
DE4106564C2 (de) 1991-03-01 1999-06-10 Bosch Gmbh Robert Vorrichtung zur elektrostatischen Zerstäubung von Flüssigkeiten
US5196171A (en) 1991-03-11 1993-03-23 In-Vironmental Integrity, Inc. Electrostatic vapor/aerosol/air ion generator
US5282982A (en) 1991-07-12 1994-02-01 Wells John R Blood washing method
GB9115278D0 (en) 1991-07-15 1991-08-28 Unilever Plc Liquid spraying apparatus and method
GB9115279D0 (en) 1991-07-15 1991-08-28 Unilever Plc Hair and scalp treatment system
GB9115277D0 (en) 1991-07-15 1991-08-28 Unilever Plc Spraying system
GB9219636D0 (en) 1991-10-10 1992-10-28 Ici Plc Spraying of liquids
WO1994013266A1 (en) 1992-05-29 1994-06-23 The Regents Of The University Of California Novel electrostatic process for manufacturing coated transplants and products
GB9225098D0 (en) * 1992-12-01 1993-01-20 Coffee Ronald A Charged droplet spray mixer
GB9226717D0 (en) 1992-12-22 1993-02-17 Coffee Ronald A Induction-operated electro-hydrodynamic spray device with means of modifying droplet trajectories
US5402945A (en) * 1993-01-22 1995-04-04 Gervan Company International Method for spraying plants and apparatus for its practice
US5409162A (en) 1993-08-09 1995-04-25 Sickles; James E. Induction spray charging apparatus
GB9406171D0 (en) * 1994-03-29 1994-05-18 Electrosols Ltd Dispensing device
GB9406255D0 (en) 1994-03-29 1994-05-18 Electrosols Ltd Dispensing device
GB9410658D0 (en) 1994-05-27 1994-07-13 Electrosols Ltd Dispensing device
US5483953A (en) 1995-04-08 1996-01-16 The United States Of America As Represented By The Secretary Of The Navy Aerosol dispensing apparatus for dispensing a medicated vapor into the lungs of a patient
GB2327895B (en) 1997-08-08 2001-08-08 Electrosols Ltd A dispensing device

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AU685411B2 (en) 1998-01-22
TW242576B (de) 1995-03-11
HK1012301A1 (en) 1999-07-30
ATE178814T1 (de) 1999-04-15
WO1994012285A3 (en) 1994-10-13
KR100289783B1 (ko) 2001-09-17
GR3030735T3 (en) 1999-11-30
CA2150692C (en) 2006-09-05
CN1104262C (zh) 2003-04-02
NZ258174A (en) 1997-03-24
EP0671980A1 (de) 1995-09-20
WO1994012285A2 (en) 1994-06-09
AU6351398A (en) 1998-07-02
NZ314209A (en) 1998-02-26
DK0671980T3 (da) 1999-10-25
JPH08504126A (ja) 1996-05-07
MX9307490A (es) 1994-08-31
EP0671980B1 (de) 1999-04-14
CA2150692A1 (en) 1994-06-09
ES2130393T3 (es) 1999-07-01
US6318640B1 (en) 2001-11-20
DE69324499T2 (de) 1999-08-12
CN1090208A (zh) 1994-08-03
ZA938895B (en) 1995-03-31
US6105877A (en) 2000-08-22
AU718118B2 (en) 2000-04-06
AU5570294A (en) 1994-06-22
GB9225098D0 (en) 1993-01-20

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