DE69326082D1 - Kalzium phosphat als hydroxyapatit-vorläufer und verfahren zur herstellung und verwendung derselben - Google Patents

Kalzium phosphat als hydroxyapatit-vorläufer und verfahren zur herstellung und verwendung derselben

Info

Publication number
DE69326082D1
DE69326082D1 DE69326082T DE69326082T DE69326082D1 DE 69326082 D1 DE69326082 D1 DE 69326082D1 DE 69326082 T DE69326082 T DE 69326082T DE 69326082 T DE69326082 T DE 69326082T DE 69326082 D1 DE69326082 D1 DE 69326082D1
Authority
DE
Germany
Prior art keywords
calcium phosphate
compositions
prepared
production
calcium
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69326082T
Other languages
English (en)
Other versions
DE69326082T2 (de
Inventor
Laurence Chow
Shozo Takagi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
American Dental Association Health Foundation
Original Assignee
American Dental Association Health Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Dental Association Health Foundation filed Critical American Dental Association Health Foundation
Publication of DE69326082D1 publication Critical patent/DE69326082D1/de
Application granted granted Critical
Publication of DE69326082T2 publication Critical patent/DE69326082T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K6/00—Preparations for dentistry
    • A61K6/50—Preparations specially adapted for dental root treatment
    • A61K6/54—Filling; Sealing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K6/00—Preparations for dentistry
    • A61K6/80—Preparations for artificial teeth, for filling teeth or for capping teeth
    • A61K6/831—Preparations for artificial teeth, for filling teeth or for capping teeth comprising non-metallic elements or compounds thereof, e.g. carbon
    • A61K6/838—Phosphorus compounds, e.g. apatite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K6/00—Preparations for dentistry
    • A61K6/80—Preparations for artificial teeth, for filling teeth or for capping teeth
    • A61K6/849—Preparations for artificial teeth, for filling teeth or for capping teeth comprising inorganic cements
    • A61K6/864—Phosphate cements
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K6/00—Preparations for dentistry
    • A61K6/80—Preparations for artificial teeth, for filling teeth or for capping teeth
    • A61K6/849—Preparations for artificial teeth, for filling teeth or for capping teeth comprising inorganic cements
    • A61K6/876—Calcium oxide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/24—Phosphorous; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/02—Surgical adhesives or cements; Adhesives for colostomy devices containing inorganic materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/02—Inorganic materials
    • A61L27/12—Phosphorus-containing materials, e.g. apatite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
    • A61F2310/00005—The prosthesis being constructed from a particular material
    • A61F2310/00179—Ceramics or ceramic-like structures
    • A61F2310/00293—Ceramics or ceramic-like structures containing a phosphorus-containing compound, e.g. apatite
DE69326082T 1993-03-12 1993-09-15 Kalzium phosphat als hydroxyapatit-vorläufer und verfahren zur herstellung und verwendung derselben Expired - Lifetime DE69326082T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/030,709 US5522893A (en) 1993-03-12 1993-03-12 Calcium phosphate hydroxyapatite precursor and methods for making and using the same
PCT/US1993/008721 WO1994020064A1 (en) 1993-03-12 1993-09-15 Calcium phosphate hydroxyapatite precursor and methods for making and using the same

Publications (2)

Publication Number Publication Date
DE69326082D1 true DE69326082D1 (de) 1999-09-23
DE69326082T2 DE69326082T2 (de) 1999-12-09

Family

ID=21855603

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69326082T Expired - Lifetime DE69326082T2 (de) 1993-03-12 1993-09-15 Kalzium phosphat als hydroxyapatit-vorläufer und verfahren zur herstellung und verwendung derselben

Country Status (11)

Country Link
US (5) US5522893A (de)
EP (1) EP0688202B1 (de)
JP (1) JP3017536B2 (de)
KR (1) KR960702294A (de)
AT (1) ATE183382T1 (de)
AU (1) AU684722B2 (de)
BR (1) BR9307825A (de)
CA (1) CA2157890C (de)
DE (1) DE69326082T2 (de)
ES (1) ES2136668T3 (de)
WO (1) WO1994020064A1 (de)

Families Citing this family (173)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9215356D0 (en) * 1992-07-20 1992-09-02 Univ Reading The Bone materials
US5522893A (en) * 1993-03-12 1996-06-04 American Dental Association Health Foundation Calcium phosphate hydroxyapatite precursor and methods for making and using the same
ES2098183B1 (es) * 1994-12-14 1998-02-01 Univ Catalunya Politecnica Producto cementante de fosfato de calcio utilizable como biomaterial.
CN1038319C (zh) * 1994-12-23 1998-05-13 上海华明超细新材料有限公司 一种制备高纯磷酸四钙的方法
US6936277B2 (en) * 1995-01-09 2005-08-30 J. Rettenmaier & Soehne Gmbh & Co. Kg Pharmaceutical excipient having improved compressibility
US6541037B1 (en) 1995-05-19 2003-04-01 Etex Corporation Delivery vehicle
US6027742A (en) * 1995-05-19 2000-02-22 Etex Corporation Bioresorbable ceramic composites
US6287341B1 (en) 1995-05-19 2001-09-11 Etex Corporation Orthopedic and dental ceramic implants
US6117456A (en) * 1995-05-19 2000-09-12 Etex Corporation Methods and products related to the physical conversion of reactive amorphous calcium phosphate
US7150879B1 (en) 1995-05-19 2006-12-19 Etex Corporation Neutral self-setting calcium phosphate paste
US5676976A (en) * 1995-05-19 1997-10-14 Etex Corporation Synthesis of reactive amorphous calcium phosphates
US6132463A (en) * 1995-05-19 2000-10-17 Etex Corporation Cell seeding of ceramic compositions
EP0830149A1 (de) * 1995-06-06 1998-03-25 Osteogenics Inc. Bioverträgliche hydroxyapatitformulierungen und ihre verwendung
US5783217A (en) * 1995-11-07 1998-07-21 Etex Corporation Low temperature calcium phosphate apatite and a method of its manufacture
US6051247A (en) * 1996-05-30 2000-04-18 University Of Florida Research Foundation, Inc. Moldable bioactive compositions
WO1998013013A1 (en) 1996-09-27 1998-04-02 Enamelon, Inc. Improved products and methods for the remineralization and prevention of demineralization of teeth
US6953594B2 (en) 1996-10-10 2005-10-11 Etex Corporation Method of preparing a poorly crystalline calcium phosphate and methods of its use
US7517539B1 (en) 1996-10-16 2009-04-14 Etex Corporation Method of preparing a poorly crystalline calcium phosphate and methods of its use
ATE381314T1 (de) 1996-10-16 2008-01-15 Etex Corp Biokeramische zusammensetzung
US8728536B2 (en) * 1996-10-16 2014-05-20 Etex Corporation Chemotherapeutic composition using nanocrystalline calcium phosphate paste
US5939039A (en) 1997-01-16 1999-08-17 Orthovita, Inc. Methods for production of calcium phosphate
US6013591A (en) 1997-01-16 2000-01-11 Massachusetts Institute Of Technology Nanocrystalline apatites and composites, prostheses incorporating them, and method for their production
NL1008582C2 (nl) * 1998-01-05 1999-07-06 Vrije Universiteit Botmateriaal.
FR2776282B1 (fr) * 1998-03-20 2000-05-19 Toulouse Inst Nat Polytech Procede de preparation d'un biomateriau a base d'hydroxyapatite, biomateriau obtenu et application chirurgicale ou dentaire
JP2002519155A (ja) * 1998-07-02 2002-07-02 スティヒティング・スケルトル・ティシュー・エンジニアリング・グループ・アムステルダム 抗微生物性ペプチドを有する骨セメント
US5858333A (en) * 1998-08-07 1999-01-12 Enamelon, Inc. Two-part oral products and methods of using same to remineralize teeth
JP4099271B2 (ja) * 1998-09-14 2008-06-11 富士通株式会社 光コネクタ
US6383519B1 (en) * 1999-01-26 2002-05-07 Vita Special Purpose Corporation Inorganic shaped bodies and methods for their production and use
AU4219100A (en) * 1999-04-07 2000-10-23 W.R. Grace & Co.-Conn. Additives for desensitizing and remineralizing dentifrice compositions
DE60041971D1 (de) 1999-07-08 2009-05-20 Cap Biotechnology Inc Calcium-enthaltende strukture und verfahren zur herstellung und verwendung davon
US6840995B2 (en) * 1999-07-14 2005-01-11 Calcitec, Inc. Process for producing fast-setting, bioresorbable calcium phosphate cements
US7169373B2 (en) * 1999-07-14 2007-01-30 Calcitec, Inc. Tetracalcium phosphate (TTCP) having calcium phosphate whisker on surface and process for preparing the same
US7270705B2 (en) * 1999-07-14 2007-09-18 Jiin-Huey Chern Lin Method of increasing working time of tetracalcium phosphate cement paste
US6960249B2 (en) * 1999-07-14 2005-11-01 Calcitec, Inc. Tetracalcium phosphate (TTCP) having calcium phosphate whisker on surface
US7094282B2 (en) * 2000-07-13 2006-08-22 Calcitec, Inc. Calcium phosphate cement, use and preparation thereof
US6379453B1 (en) * 1999-07-14 2002-04-30 Jiin-Huey Chern Process for producing fast-setting, bioresorbable calcium phosphate cements
US6458162B1 (en) * 1999-08-13 2002-10-01 Vita Special Purpose Corporation Composite shaped bodies and methods for their production and use
WO2001012129A1 (en) * 1999-08-13 2001-02-22 Jeneric/Pentron Incorporated Dental compositions comprising degradable polymers
FR2805748B1 (fr) * 2000-03-01 2002-09-13 Ceravic Procede de preparation d'un materiau pateux phosphocalcique injectable en vue de former un biomateriau apatitique et application chirurgicale ou dentaire
US7820191B2 (en) 2000-04-28 2010-10-26 Skeletal Kinetics, Llc Calcium phosphate cements prepared from silicate solutions
US6375935B1 (en) 2000-04-28 2002-04-23 Brent R. Constantz Calcium phosphate cements prepared from silicate solutions
DE10032220A1 (de) * 2000-07-03 2002-01-24 Sanatis Gmbh Magnesium-ammonium-phosphat-Zemente, deren Herstellung und Verwendung
US7156915B2 (en) * 2000-07-13 2007-01-02 Calcitec, Inc. Tetracalcium phosphate (TTCP) with surface whiskers and method of making same
US7160382B2 (en) * 2000-07-13 2007-01-09 Calcitec, Inc. Calcium phosphate cements made from (TTCP) with surface whiskers and process for preparing same
US6787584B2 (en) * 2000-08-11 2004-09-07 Pentron Corporation Dental/medical compositions comprising degradable polymers and methods of manufacture thereof
US6551273B1 (en) 2000-08-23 2003-04-22 Scimed Life Systems, Inc. Catheter having a shaft keeper
JP2004511320A (ja) * 2000-10-16 2004-04-15 ユニバーシテイ・オブ・サウス・カロライナ 反応性リン酸カルシウムナノ粒子を含む生体適合性セメント並びに前記セメントの製造及び使用方法
US6736799B1 (en) 2000-10-24 2004-05-18 Vita Licensing, Inc. Delivery device for biological composites and method of preparation thereof
US7052517B2 (en) * 2000-10-24 2006-05-30 Vita Special Purpose Corporation Delivery device for biological composites and method of preparation thereof
AU2007221771B2 (en) * 2000-11-16 2010-04-01 Biotomo Pty Ltd Processes for treating coral and coating an object
US20020114795A1 (en) 2000-12-22 2002-08-22 Thorne Kevin J. Composition and process for bone growth and repair
US6793725B2 (en) 2001-01-24 2004-09-21 Ada Foundation Premixed calcium phosphate cement pastes
US7294187B2 (en) * 2001-01-24 2007-11-13 Ada Foundation Rapid-hardening calcium phosphate cement compositions
US7709029B2 (en) * 2001-01-24 2010-05-04 Ada Foundation Calcium-containing restoration materials
WO2002079112A1 (fr) * 2001-03-28 2002-10-10 Mitsubishi Materials Corporation Produit petri contenant un ciment de phosphate de calcium et son procede de preparation
CA2442855A1 (en) 2001-04-12 2002-10-24 Therics, Inc. Method and apparatus for engineered regenerative biostructures
US20030055512A1 (en) * 2001-05-21 2003-03-20 Genin Francois Y. Calcium based neutral and bioresorbable bone graft
US6616742B2 (en) 2001-08-30 2003-09-09 Cana Lab Corporation Process for preparing a paste from calcium phosphate cement
ES2545256T3 (es) * 2001-11-14 2015-09-09 Ecole polytechnique fédérale de Lausanne (EPFL) Multicomponentes pastosos para cementos fosfocálcicos inyectables
US6878168B2 (en) 2002-01-03 2005-04-12 Edwards Lifesciences Corporation Treatment of bioprosthetic tissues to mitigate post implantation calcification
US6955716B2 (en) 2002-03-01 2005-10-18 American Dental Association Foundation Self-hardening calcium phosphate materials with high resistance to fracture, controlled strength histories and tailored macropore formation rates
US20040137032A1 (en) * 2002-03-15 2004-07-15 Wang Francis W. Combinations of calcium phosphates, bone growth factors, and pore-forming additives as osteoconductive and osteoinductive composite bone grafts
EP1364661A1 (de) * 2002-05-15 2003-11-26 Central Medical Technologies Inc. Calciumsulfat-Zusammensetzung mit kontrollierbarer Verarbeitungszeit zur Knochenbehandlung
US20030216777A1 (en) * 2002-05-16 2003-11-20 Yin-Chun Tien Method of enhancing healing of interfacial gap between bone and tendon or ligament
US7273523B2 (en) 2002-06-07 2007-09-25 Kyphon Inc. Strontium-apatite-cement-preparations, cements formed therefrom, and uses thereof
NZ538196A (en) * 2002-08-12 2007-05-31 Osteotech Inc Synthesis of a bone-polymer composite material for forming osteoimplants
US20050251267A1 (en) * 2004-05-04 2005-11-10 John Winterbottom Cell permeable structural implant
US9107751B2 (en) 2002-12-12 2015-08-18 Warsaw Orthopedic, Inc. Injectable and moldable bone substitute materials
US20040141903A1 (en) * 2003-01-17 2004-07-22 Howmedica Osteonics Corp. Calcium phosphate cement precursors
US7985414B2 (en) * 2003-02-04 2011-07-26 Warsaw Orthopedic, Inc. Polyurethanes for osteoimplants
CA2514336C (en) 2003-02-04 2013-05-14 Osteotech, Inc. Polyurethanes for osteoimplants
EP3254710B1 (de) * 2003-04-11 2019-05-22 Etex Corporation Osteoinduktives knochenmaterial
US20040250730A1 (en) * 2003-06-12 2004-12-16 David Delaney Calcium phosphate cements prepared from silicate-phosphate solutions
US20040250729A1 (en) * 2003-06-16 2004-12-16 Jang Bor Z. Fast-setting carbonated hydroxyapatite compositions and uses
US20040254668A1 (en) * 2003-06-16 2004-12-16 Jang Bor Z. Macro-porous hydroxyapatite scaffold compositions and freeform fabrication method thereof
EP1641426A1 (de) * 2003-07-02 2006-04-05 Ada Foundation Remineralisierende dentalzemente
US7306786B2 (en) 2003-07-28 2007-12-11 Skeletal Kinetics, Llc Calcium phosphate cements comprising a water-soluble contrast agent
US6994726B2 (en) * 2004-05-25 2006-02-07 Calcitec, Inc. Dual function prosthetic bone implant and method for preparing the same
US7118705B2 (en) * 2003-08-05 2006-10-10 Calcitec, Inc. Method for making a molded calcium phosphate article
US7163651B2 (en) * 2004-02-19 2007-01-16 Calcitec, Inc. Method for making a porous calcium phosphate article
US7261718B2 (en) 2003-09-11 2007-08-28 Skeletal Kinetics Llc Use of vibration with polymeric bone cements
US7261717B2 (en) 2003-09-11 2007-08-28 Skeletal Kinetics Llc Methods and devices for delivering orthopedic cements to a target bone site
CA2545185A1 (en) * 2003-11-07 2005-05-26 Calcitec, Inc. Spinal fusion procedure using an injectable bone substitute
US7252833B2 (en) * 2003-11-18 2007-08-07 Skeletal Kinetics, Llc Calcium phosphate cements comprising an osteoclastogenic agent
CA2550431A1 (en) * 2003-12-19 2005-07-14 Osteotech, Inc. Tissue-derived mesh for orthopedic regeneration
US8012210B2 (en) 2004-01-16 2011-09-06 Warsaw Orthopedic, Inc. Implant frames for use with settable materials and related methods of use
AU2005210630A1 (en) * 2004-01-30 2005-08-18 Warsaw Orthopedic, Inc. Stacking implants for spinal fusion
US7189263B2 (en) * 2004-02-03 2007-03-13 Vita Special Purpose Corporation Biocompatible bone graft material
US9707024B2 (en) 2004-03-09 2017-07-18 Skeletal Kinetics, Llc Use of vibration in composite fixation
US8118812B2 (en) 2004-03-09 2012-02-21 Skeletal Kinetics, Llc Use of vibration in composite fixation
AU2005249365B2 (en) * 2004-04-15 2011-04-07 Etex Corporation Delayed-setting calcium phosphate pastes
ES2396133T3 (es) 2004-04-27 2013-02-19 Kyphon SÀRl Composiciones de sustitución osea y método de uso
DE102004025030A1 (de) * 2004-05-18 2005-12-15 S&C Polymer Silicon- und Composite-Spezialitäten GmbH Nano-Apatit-Füllstoffe enthaltende härtbare Restaurationsmaterialien
US7252841B2 (en) * 2004-05-20 2007-08-07 Skeletal Kinetics, Llc Rapid setting calcium phosphate cements
US20050257714A1 (en) * 2004-05-20 2005-11-24 Constantz Brent R Orthopedic cements comprising a barium apatite contrast agent
EP1604693A1 (de) * 2004-06-09 2005-12-14 Scil Technology GmbH In-situ hergestelltes Gerüst, dessen Herstellungsverfahren und dessen Verwendung
US9220595B2 (en) 2004-06-23 2015-12-29 Orthovita, Inc. Shapeable bone graft substitute and instruments for delivery thereof
US7175858B2 (en) * 2004-07-26 2007-02-13 Skeletal Kinetics Llc Calcium phosphate cements and methods for using the same
WO2006030782A1 (ja) * 2004-09-14 2006-03-23 Japan Science And Technology Agency セラミック粒子群およびその製造方法並びにその利用
US20080050408A1 (en) * 2004-11-26 2008-02-28 Discus Dental, Llc Dental Whitening Compositions
US20060115437A1 (en) * 2004-11-26 2006-06-01 Robert Hayman Dental whitening compositions
US7312989B2 (en) * 2004-12-06 2007-12-25 Chenbro Micom Co., Ltd. Cooler
US7713542B2 (en) 2005-01-14 2010-05-11 Ada Foundation Three dimensional cell protector/pore architecture formation for bone and tissue constructs
US8480629B2 (en) 2005-01-28 2013-07-09 Boston Scientific Scimed, Inc. Universal utility board for use with medical devices and methods of use
US20060173477A1 (en) * 2005-02-03 2006-08-03 Lin Jiin-Huey C Dual function prosthetic bone implant and method for preparing the same
US20060198863A1 (en) * 2005-03-03 2006-09-07 Musculoskeletal Transplant Foundation Ceramic composition for filling bone defects
US7416602B2 (en) * 2005-04-08 2008-08-26 Howmedica Leibinger, Inc. Calcium phosphate cement
US7459018B2 (en) * 2005-04-08 2008-12-02 Howmedica Leibinger Inc. Injectable calcium phosphate cement
US9060820B2 (en) 2005-05-18 2015-06-23 Sonoma Orthopedic Products, Inc. Segmented intramedullary fracture fixation devices and methods
US8961516B2 (en) 2005-05-18 2015-02-24 Sonoma Orthopedic Products, Inc. Straight intramedullary fracture fixation devices and methods
WO2006124764A1 (en) 2005-05-18 2006-11-23 Sonoma Orthopedic Products, Inc. Minimally invasive actuable bone fixation devices, systems and methods of use
US20070123604A1 (en) * 2005-05-26 2007-05-31 Ada Foundation Dental releasing materials
US20060270752A1 (en) * 2005-05-26 2006-11-30 Ada Foundation Dental releasing materials
US7651701B2 (en) * 2005-08-29 2010-01-26 Sanatis Gmbh Bone cement composition and method of making the same
US9259439B2 (en) * 2005-10-21 2016-02-16 Ada Foundation Dual-phase cement precursor systems for bone repair
US9101436B2 (en) * 2005-10-21 2015-08-11 Ada Foundation Dental and endodontic filling materials and methods
WO2007047994A2 (en) * 2005-10-21 2007-04-26 Ada Foundation Dental and endodontic filling materials and methods
EP1962914B1 (de) 2005-11-14 2019-02-27 Biomet 3i, LLC Abscheidung von diskreten nanoteilchen auf einer implantatoberfläche
US8147860B2 (en) 2005-12-06 2012-04-03 Etex Corporation Porous calcium phosphate bone material
US8287914B2 (en) * 2006-01-12 2012-10-16 Rutgers, The State University Of New Jersey Biomimetic hydroxyapatite synthesis
JP5180591B2 (ja) 2006-01-16 2013-04-10 クラレノリタケデンタル株式会社 リン酸カルシウム粉体組成物及びリン酸カルシウム組成物ペーストの製造方法
EP1976459A4 (de) 2006-01-19 2012-06-20 Warsaw Orthopedic Inc Poröses knochenimplantat
US8518383B2 (en) * 2006-02-03 2013-08-27 Wm. Wrigley Jr. Company Oral care products comprising buffer systems for improved mineralization/remineralization benefits
US7754005B2 (en) * 2006-05-02 2010-07-13 Kyphon Sarl Bone cement compositions comprising an indicator agent and related methods thereof
US7507286B2 (en) * 2006-06-08 2009-03-24 Sanatis Gmbh Self-foaming cement for void filling and/or delivery systems
EP2422822A1 (de) 2006-06-29 2012-02-29 Orthovita, Inc. Bioaktiver Knochentransplantatersatz
WO2008039382A2 (en) * 2006-09-21 2008-04-03 Kyphon Sarl Diammonium phosphate and other ammonium salts and their use in preventing clotting
EP2079401B1 (de) * 2006-10-24 2019-05-22 Biomet 3i, LLC Ablagerung diskreter nanopartikel auf einer nanostrukturierten oberfläche eines implantats
WO2008073190A2 (en) * 2006-11-03 2008-06-19 Kyphon Sarl Materials and methods and systems for delivering localized medical treatments
CA2670263A1 (en) 2006-11-22 2008-05-29 Sonoma Orthopedic Products, Inc. Fracture fixation device, tools and methods
US7718616B2 (en) 2006-12-21 2010-05-18 Zimmer Orthobiologics, Inc. Bone growth particles and osteoinductive composition thereof
US8288344B2 (en) * 2007-03-15 2012-10-16 Musculoskeletal Transplant Foundation Ceramic composition for filling bone defects
EP2134649A1 (de) * 2007-04-13 2009-12-23 Dr.h.c. Robert Mathys Stiftung Verfahren zur herstellung von pyrogenfreiem calciumphosphat
US20090036564A1 (en) * 2007-08-03 2009-02-05 Feng-Huei Lin Bio-Degenerable Bone Cement and Manufacturing Method thereof
US8357387B2 (en) 2007-12-21 2013-01-22 Edwards Lifesciences Corporation Capping bioprosthetic tissue to reduce calcification
JP5806466B2 (ja) * 2008-01-28 2015-11-10 バイオメット・３アイ・エルエルシー 親水性を向上させたインプラント表面
US20090198345A1 (en) * 2008-02-04 2009-08-06 Chung Shan Medical University Calcium silicate-based composite cement and manufacturing method thereof
CA2719798A1 (en) * 2008-03-28 2009-10-01 Osteotech, Inc. Bone anchors for orthopedic applications
US7968616B2 (en) * 2008-04-22 2011-06-28 Kyphon Sarl Bone cement composition and method
WO2009152273A1 (en) 2008-06-10 2009-12-17 Sonoma Orthopedic Products, Inc. Fracture fixation device, tools and methods
GB0813659D0 (en) * 2008-07-25 2008-09-03 Smith & Nephew Fracture putty
CA2738478A1 (en) 2008-09-26 2010-04-01 Sonoma Orthopedic Products, Inc. Bone fixation device, tools and methods
US9333276B2 (en) * 2008-10-30 2016-05-10 Vanderbilt University Bone/polyurethane composites and methods thereof
WO2012134540A2 (en) 2010-10-22 2012-10-04 Vanderbilt University Injectable synthetic pur composite
KR101769805B1 (ko) 2008-11-12 2017-08-21 스트리커 디벨롭먼트, 엘엘씨 테트라 칼슘 포스페이트 기재 유기인계 조성물 및 방법
JP5501346B2 (ja) * 2009-03-30 2014-05-21 クラレノリタケデンタル株式会社 歯牙石灰化剤の製造方法
JPWO2010113800A1 (ja) * 2009-03-30 2012-10-11 クラレノリタケデンタル株式会社 象牙質石灰化剤及びその製造方法
EP2421543B1 (de) * 2009-04-22 2019-06-12 American Dental Association Foundation Zweiphasen-calciumphosphatzementzusammensetzung
US8741268B2 (en) * 2009-09-10 2014-06-03 Preventive Technologies, Inc. Dental prophylactic paste
US8142194B2 (en) * 2009-11-16 2012-03-27 Innovative Health Technologies, Llc Implants and methods for performing gums and bone augmentation and preservation
CA2784533C (en) 2009-12-18 2016-02-09 Howmedica Osteonics Corp. Post irradiation shelf-stable dual paste direct injectable bone cement precursor systems and methods of making same
US20110151027A1 (en) * 2009-12-21 2011-06-23 Theodore D Clineff Strontium-doped calcium phosphate bone graft materials
JP5487410B2 (ja) 2010-02-22 2014-05-07 国立大学法人 岡山大学 生体硬組織接着用キット
US8641418B2 (en) 2010-03-29 2014-02-04 Biomet 3I, Llc Titanium nano-scale etching on an implant surface
CA3048850A1 (en) 2010-05-11 2011-11-17 Howmedica Osteonics Corp. Organophosphorous, multivalent metal compounds, & polymer adhesive interpenetrating network compositions & methods
GB201016970D0 (en) * 2010-10-08 2010-11-24 Univ Leeds Composition
ES2714701T3 (es) 2010-11-10 2019-05-29 Stryker European Holdings I Llc Proceso para la preparación de una espuma ósea polimérica
US8613938B2 (en) 2010-11-15 2013-12-24 Zimmer Orthobiologics, Inc. Bone void fillers
US8551525B2 (en) 2010-12-23 2013-10-08 Biostructures, Llc Bone graft materials and methods
WO2012129234A1 (en) 2011-03-21 2012-09-27 Endo Pharmaceuticals Inc. Urethral anastomosis device and method
WO2012158527A2 (en) 2011-05-13 2012-11-22 Howmedica Osteonics Organophosphorous & multivalent metal compound compositions & methods
US9131995B2 (en) 2012-03-20 2015-09-15 Biomet 3I, Llc Surface treatment for an implant surface
WO2014047061A1 (en) 2012-09-18 2014-03-27 Endo Pharmaceuticals Inc. Urethral anastomosis device
US20160074041A1 (en) 2013-03-14 2016-03-17 Endo Pharmaceuticals Inc. Urethral anastomosis device and method
US9168114B2 (en) 2013-10-17 2015-10-27 B & D Dental Corp. Method of making a dental prosthesis
US9770278B2 (en) 2014-01-17 2017-09-26 Arthrex, Inc. Dual tip guide wire
GB201417020D0 (en) * 2014-09-26 2014-11-12 Univ Leeds And Univ St Andrews The Formulation
US9814499B2 (en) 2014-09-30 2017-11-14 Arthrex, Inc. Intramedullary fracture fixation devices and methods
US10219986B2 (en) 2015-03-04 2019-03-05 Modern Ideas LLC Stabilized calcium phosphate and methods of forming same
US9956314B2 (en) 2016-01-26 2018-05-01 Modern Ideas LLC Adhesive for use with bone and bone-like structures
EP3551330A1 (de) * 2016-12-07 2019-10-16 Solvay SA Kupfergeträgerter katalysator mit einem ca-defizienten hydroxylapatit zur abgas-nox-entfernung
US11752072B2 (en) 2019-03-11 2023-09-12 University Of Utah Research Foundation Quick set cements for dental pulp capping and related methods of use
US20230120190A1 (en) 2020-01-29 2023-04-20 Marcelo Rodrigues Teixeira Oral composition with synergistic association of organic and inorganic components for full maintenance of oral health, process for obtaining and uses thereof

Family Cites Families (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2008010C3 (de) * 1970-02-20 1980-07-10 Schneider Gmbh & Co, 5020 Frechen Verfahren zur Herstellung von Dentalimplantaten
US3679360A (en) * 1970-06-26 1972-07-25 Nasa Process for the preparation of brushite crystals
US3787900A (en) * 1971-06-09 1974-01-29 Univ Iowa State Res Found Artificial bone or tooth prosthesis material
US3929971A (en) * 1973-03-30 1975-12-30 Research Corp Porous biomaterials and method of making same
US3913229A (en) * 1974-02-25 1975-10-21 Miter Inc Dental treatments
US4097935A (en) * 1976-07-21 1978-07-04 Sterling Drug Inc. Hydroxylapatite ceramic
DE2928007A1 (de) * 1979-07-11 1981-01-15 Riess Guido Dr Knochen-implantatkoerper fuer prothesen und knochenverbindungsstuecke sowie verfahren zu seiner herstellung
JPS5654841A (en) * 1979-10-08 1981-05-15 Mitsubishi Mining & Cement Co Bone broken portion and filler for void portion and method of treating bone of animal using said filler
JPS5858041A (ja) * 1981-10-05 1983-04-06 三菱鉱業セメント株式会社 骨欠損部及び空隙部充てん材
USRE33221E (en) * 1982-04-29 1990-05-22 American Dental Association Health Foundation Dental restorative cement pastes
USRE33161E (en) * 1982-04-29 1990-02-06 American Dental Association Health Foundation Combinations of sparingly soluble calcium phosphates in slurries and pastes as mineralizers and cements
US4612053A (en) * 1983-10-06 1986-09-16 American Dental Association Health Foundation Combinations of sparingly soluble calcium phosphates in slurries and pastes as mineralizers and cements
JPH0822731B2 (ja) * 1986-05-21 1996-03-06 昭和電工株式会社 歯科材料用Ｃａ▲下４▼Ｐ▲下２▼Ｏ▲下９▼粉末の製造法
JP2543685B2 (ja) * 1986-10-31 1996-10-16 旭光学工業株式会社 リン酸カルシウムの製造方法
JP2501213B2 (ja) 1987-07-27 1996-05-29 住友大阪セメント株式会社 骨接着剤
US4880610A (en) * 1988-04-20 1989-11-14 Norian Corporation In situ calcium phosphate minerals--method and composition
US5047031A (en) * 1988-04-20 1991-09-10 Norian Corporation In situ calcium phosphate minerals method
US5129905A (en) * 1988-04-20 1992-07-14 Norian Corporation Methods for in situ prepared calcium phosphate minerals
US5053212A (en) * 1988-04-20 1991-10-01 Norian Corporation Intimate mixture of calcium and phosphate sources as precursor to hydroxyapatite
JPH0643263B2 (ja) 1988-05-31 1994-06-08 徳山曹達株式会社 硬化性組成物
JPH0773602B2 (ja) * 1988-07-23 1995-08-09 新田ゼラチン株式会社 医科用および歯科用硬化性材料
US5034059A (en) * 1989-02-17 1991-07-23 Norian Corporation Composition comprising octacalcium phosphate crystals and polypeptide
JPH0645487B2 (ja) 1989-05-19 1994-06-15 徳山曹達株式会社 硬化材
US5037639A (en) * 1989-05-24 1991-08-06 American Dental Association Health Foundation Methods and compositions for mineralizing calcified tissues
JP2584877B2 (ja) 1989-12-08 1997-02-26 共立窯業原料株式会社 リン酸四カルシウムの製造方法
JP2535424B2 (ja) * 1989-12-22 1996-09-18 共立窯業原料株式会社 リン酸四カルシウムの製造法
JPH0780683B2 (ja) 1990-06-27 1995-08-30 大阪セメント株式会社 リン酸四カルシウムおよびリン酸四カルシウム硬化体
GB2246770B (en) * 1990-07-27 1995-03-29 Osaka Cement Tetracalcium phosphate-based hardening materials
US5037634A (en) * 1990-08-16 1991-08-06 Chesebrough-Pond's Usa Co., Division Of Conopco, Inc. Oral compositions containing stabilized copper
EP0520690B1 (de) * 1991-06-26 1995-11-02 Nitta Gelatin Inc. Härtbares kalziumphosphathaltiges Material zum Reparieren von lebenden Hartgeweben
CA2070047A1 (en) * 1991-06-28 1992-12-29 Richard J. Sadey Metal foil with improved peel strength and method for making said foil
US5522893A (en) * 1993-03-12 1996-06-04 American Dental Association Health Foundation Calcium phosphate hydroxyapatite precursor and methods for making and using the same
JP3183605B2 (ja) 1994-06-09 2001-07-09 日本電信電話株式会社 波長多重光ソリトン伝送を行うシステム

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CA2157890A1 (en) 1994-09-15
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AU4923993A (en) 1994-09-26
US5695729A (en) 1997-12-09
US5542973A (en) 1996-08-06
JP3017536B2 (ja) 2000-03-13
US6325992B1 (en) 2001-12-04
KR960702294A (ko) 1996-04-27
US5545254A (en) 1996-08-13
US5522893A (en) 1996-06-04
AU684722B2 (en) 1998-01-08
ATE183382T1 (de) 1999-09-15
ES2136668T3 (es) 1999-12-01
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