DE69326149T2 - (3R,4R)--g(D)?6-TETRAHYDROCANNABINOL-7-CARBONSÄUREN - Google Patents

(3R,4R)--g(D)?6-TETRAHYDROCANNABINOL-7-CARBONSÄUREN

Info

Publication number
DE69326149T2
DE69326149T2 DE69326149T DE69326149T DE69326149T2 DE 69326149 T2 DE69326149 T2 DE 69326149T2 DE 69326149 T DE69326149 T DE 69326149T DE 69326149 T DE69326149 T DE 69326149T DE 69326149 T2 DE69326149 T2 DE 69326149T2
Authority
DE
Germany
Prior art keywords
tetrahydrocannabinol
carbonic acids
carbonic
acids
thc
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69326149T
Other languages
English (en)
Other versions
DE69326149D1 (de
Inventor
Sumner Burstein
Raphael Mechoulam
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Application granted granted Critical
Publication of DE69326149D1 publication Critical patent/DE69326149D1/de
Publication of DE69326149T2 publication Critical patent/DE69326149T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78—Ring systems having three or more relevant rings
    • C07D311/80—Dibenzopyrans; Hydrogenated dibenzopyrans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
DE69326149T 1992-07-14 1993-07-13 (3R,4R)--g(D)?6-TETRAHYDROCANNABINOL-7-CARBONSÄUREN Expired - Fee Related DE69326149T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/913,096 US5338753A (en) 1992-07-14 1992-07-14 (3R,4R)-Δ6 -tetrahydrocannabinol-7-oic acids useful as antiinflammatory agents and analgesics
PCT/US1993/006580 WO1994001429A1 (en) 1992-07-14 1993-07-13 (3r,4r)-δ6-tetrahydrocannabinol-7-oic acids

Publications (2)

Publication Number Publication Date
DE69326149D1 DE69326149D1 (de) 1999-09-30
DE69326149T2 true DE69326149T2 (de) 2000-04-27

Family

ID=25432922

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69326149T Expired - Fee Related DE69326149T2 (de) 1992-07-14 1993-07-13 (3R,4R)--g(D)?6-TETRAHYDROCANNABINOL-7-CARBONSÄUREN

Country Status (13)

Country Link
US (1) US5338753A (de)
EP (1) EP0650483B1 (de)
JP (1) JP3278159B2 (de)
KR (1) KR100289202B1 (de)
AT (1) ATE183744T1 (de)
AU (1) AU676845B2 (de)
CA (1) CA2140368C (de)
DE (1) DE69326149T2 (de)
DK (1) DK0650483T3 (de)
ES (1) ES2138626T3 (de)
GR (1) GR3031966T3 (de)
HK (1) HK1010690A1 (de)
WO (1) WO1994001429A1 (de)

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US5635530A (en) * 1991-09-12 1997-06-03 Yissum Research Development Company Of The Hebrew University Of Jerusalem (3S,4S)-delta-6-tetrahydrocannabinol-7-oic acids and derivatives thereof, processors for their preparation and pharmaceutical compositions containing them
IL115245A (en) 1995-09-11 2002-12-01 Yissum Res Dev Co Tumor necrosis factor inhibiting pharmaceuticals
US6132762A (en) * 1997-05-05 2000-10-17 Cristobal; Walter Transcutaneous application of marijuana
US6162829A (en) * 1997-10-17 2000-12-19 Atlantic Pharmaceuticals, Inc. (3R,4R)-Δ8 -tetrahydrocannabinol-11-oic acids useful as antiinflammatory agents and analgesics
GB9807639D0 (en) 1998-04-14 1998-06-10 Kennedy Rheumatology Inst Anti-inflammatory agents
US5847128A (en) * 1998-05-29 1998-12-08 Virginia Commonwealth University Water soluble derivatives of cannabinoids
US6566560B2 (en) 1999-03-22 2003-05-20 Immugen Pharmaceuticals, Inc. Resorcinolic compounds
EP1189603A2 (de) 1999-03-22 2002-03-27 Immugen Pharmaceuticals, Inc. Behandlung von immunerkrankungen wie hiv-erkrankung und neoplastischen erkrankungen
US6448288B1 (en) 2000-05-17 2002-09-10 University Of Massachusetts Cannabinoid drugs
US20020137802A1 (en) * 2000-09-28 2002-09-26 Travis Craig R. Methods and compounds for inhibiting eicosanoid metabolism and platelet aggregation
WO2002026728A2 (en) * 2000-09-28 2002-04-04 Immugen Pharmaceuticals, Inc. Antiviral methods and compounds
US7067539B2 (en) * 2001-02-08 2006-06-27 Schering Corporation Cannabinoid receptor ligands
US7507767B2 (en) * 2001-02-08 2009-03-24 Schering Corporation Cannabinoid receptor ligands
AU2002318427A1 (en) * 2001-06-25 2003-03-03 University Of Massachusetts N-fatty acid-amino acid conjugates and therapeutic uses
DE60234057D1 (de) 2001-07-25 2009-11-26 Raptor Pharmaceutical Inc Zusammensetzungen und verfahren zur modulation des transports durch die blut-hirn-schranke
NZ532291A (en) * 2001-11-14 2005-11-25 Schering Corp Cannabinoid receptor ligands
PT1477186E (pt) 2002-02-19 2010-02-11 Shionogi & Co Antipruriginosos
AU2003214226A1 (en) * 2002-03-18 2003-10-08 Immugen Pharmaceuticals, Inc. Topical formulations of resorcinols and cannibinoids and methods of use
EP1539693B9 (de) 2002-06-19 2008-10-08 Schering Corporation Agonisten des cannabinoidrezeptors
MXPA05005512A (es) 2002-11-25 2005-07-25 Schering Corp Ligandos receptores canabinoides.
WO2004058251A1 (en) * 2002-12-19 2004-07-15 University Of Massachusetts Cannabinoid analogs as peroxisome proliferator activated nuclear receptor gamma activators
AR043633A1 (es) * 2003-03-20 2005-08-03 Schering Corp Ligandos de receptores de canabinoides
US20050070596A1 (en) * 2003-05-12 2005-03-31 David Baker Methods for treatment of inflammatory diseases using CT-3 or analogs thereof
US6916852B2 (en) * 2003-05-12 2005-07-12 University Of Tennessee Research Foundation Method for regulation of microvascular tone
EP2259050A3 (de) * 2003-08-26 2010-12-22 Blueshift Biotechnologies, Inc. Zeitabhängige Fluoreszenzmessungen
WO2005081801A2 (en) * 2004-02-09 2005-09-09 Blueshift Biotechnologies, Inc. Methods and apparatus for scanning small sample volumes
ES2332416T3 (es) * 2004-06-22 2010-02-04 Schering Corporation Ligandos de receptores cannabinoides.
US7141378B2 (en) 2004-07-02 2006-11-28 Blueshift Biotechnologies, Inc. Exploring fluorophore microenvironments
US7544714B2 (en) * 2004-07-16 2009-06-09 University Of Massachusetts Lipid-amino acid conjugates and methods of use
WO2006065793A2 (en) 2004-12-13 2006-06-22 Indevus Pharmaceuticals, Inc. TREATMENT OF INTERSTITIAL CYSTITIS USING (6aR,10aR)-Δ8-TETRAHYDROCANNABINOL-11-OIC ACIDS
WO2006065792A2 (en) * 2004-12-13 2006-06-22 Indevus Pharmaceuticals, Inc. Treatment of interstitial cystitis using cannabinoid analogs
EP3827747A1 (de) 2005-04-28 2021-06-02 Otsuka Pharmaceutical Co., Ltd. Pharmainformatiksystem
TWI366460B (en) 2005-06-16 2012-06-21 Euro Celtique Sa Cannabinoid active pharmaceutical ingredient for improved dosage forms
US20070037873A1 (en) * 2005-08-08 2007-02-15 Zurier Robert B Airway remodeling treatments
ZA200802767B (en) * 2005-09-29 2009-09-30 Amr Technology Inc Process for production of delta-9-tetrahydrocannabinol
US20070093519A1 (en) * 2005-10-20 2007-04-26 Indevus Pharmaceuticals, Inc. Anti-emetic uses of cannabinoid analogs
US20070099988A1 (en) * 2005-10-31 2007-05-03 Indevus Pharmaceuticals, Inc. Anti-emetic uses of (3r, 4r)-delta8-tetrahydrocannabinol-11-oic acids
CA2663377A1 (en) 2006-09-18 2008-03-27 Raptor Pharmaceutical Inc. Treatment of liver disorders by administration of receptor-associated protein (rap)-conjugates
EP2398500B1 (de) 2009-02-20 2019-03-13 2-BBB Medicines B.V. Arzneiabgabesystem auf glutathion-basis
SG10201402069PA (en) 2009-05-06 2014-07-30 Lab Skin Care Inc Dermal delivery compositions comprising active agent-calcium phosphate particle complexes and methods of using the same
US9066910B2 (en) * 2010-04-15 2015-06-30 Steven Rosenblatt Methods and compositions of cannabis extracts
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates
EP2956133A4 (de) 2013-02-12 2016-12-21 Corbus Pharmaceuticals Inc Ultrareine tetrahydrocannabinol-11-on-säuren
US9585867B2 (en) 2015-08-06 2017-03-07 Charles Everett Ankner Cannabinod formulation for the sedation of a human or animal
US10239808B1 (en) 2016-12-07 2019-03-26 Canopy Holdings, LLC Cannabis extracts
CA3089994A1 (en) 2018-01-31 2019-08-08 Canopy Holdings, LLC Hemp powder
EP3864000A4 (de) 2018-10-10 2022-08-10 Treehouse Biosciences, Inc. Synthese von cannabigerol
WO2021034403A1 (en) 2019-08-22 2021-02-25 Epm Group, Inc. Cannabinoid acid ester compositions and uses thereof
CA3154437A1 (en) * 2019-10-11 2021-04-15 Corbus Pharmaceuticals, Inc. Compositions of ajulemic acid and uses thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4973603A (en) * 1988-06-16 1990-11-27 Sumner Burstein Platelet activating factor antagonist and methods of use therefor
IL99468A (en) * 1991-09-12 1997-09-30 Yissum Res Dev Co (3s, 4s)-delta- 6-tetrahydrocannabinol- 7-oic acids and derivatives thereof, processes for their preparation and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
US5338753A (en) 1994-08-16
JPH08500096A (ja) 1996-01-09
AU4675993A (en) 1994-01-31
EP0650483B1 (de) 1999-08-25
JP3278159B2 (ja) 2002-04-30
KR100289202B1 (ko) 2001-05-02
CA2140368C (en) 2004-04-27
ES2138626T3 (es) 2000-01-16
WO1994001429A1 (en) 1994-01-20
ATE183744T1 (de) 1999-09-15
KR950702549A (ko) 1995-07-29
GR3031966T3 (en) 2000-03-31
CA2140368A1 (en) 1994-01-20
AU676845B2 (en) 1997-03-27
DK0650483T3 (da) 2000-03-27
EP0650483A4 (en) 1995-05-10
DE69326149D1 (de) 1999-09-30
EP0650483A1 (de) 1995-05-03
HK1010690A1 (en) 1999-06-25

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee