DE69327057D1 - Polyarylate, die derivate der natürlichen aminosäure l-tyrosin enthalten - Google Patents
Polyarylate, die derivate der natürlichen aminosäure l-tyrosin enthaltenInfo
- Publication number
- DE69327057D1 DE69327057D1 DE69327057T DE69327057T DE69327057D1 DE 69327057 D1 DE69327057 D1 DE 69327057D1 DE 69327057 T DE69327057 T DE 69327057T DE 69327057 T DE69327057 T DE 69327057T DE 69327057 D1 DE69327057 D1 DE 69327057D1
- Authority
- DE
- Germany
- Prior art keywords
- amino acid
- natural amino
- tyrosine
- polyarylates
- containing derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 229920001230 polyarylate Polymers 0.000 title abstract 3
- 150000001413 amino acids Chemical class 0.000 title abstract 2
- OUYCCCASQSFEME-QMMMGPOBSA-N L-tyrosine Chemical compound OC(=O)[C@@H](N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-QMMMGPOBSA-N 0.000 title 1
- XKZQKPRCPNGNFR-UHFFFAOYSA-N 2-(3-hydroxyphenyl)phenol Chemical compound OC1=CC=CC(C=2C(=CC=CC=2)O)=C1 XKZQKPRCPNGNFR-UHFFFAOYSA-N 0.000 abstract 1
- 239000000599 controlled substance Substances 0.000 abstract 1
- 150000001991 dicarboxylic acids Chemical class 0.000 abstract 1
- 238000012377 drug delivery Methods 0.000 abstract 1
- 239000007858 starting material Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G64/00—Macromolecular compounds obtained by reactions forming a carbonic ester link in the main chain of the macromolecule
- C08G64/04—Aromatic polycarbonates
- C08G64/06—Aromatic polycarbonates not containing aliphatic unsaturation
- C08G64/08—Aromatic polycarbonates not containing aliphatic unsaturation containing atoms other than carbon, hydrogen or oxygen
- C08G64/12—Aromatic polycarbonates not containing aliphatic unsaturation containing atoms other than carbon, hydrogen or oxygen containing nitrogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
- A61K9/204—Polyesters, e.g. poly(lactide-co-glycolide)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C235/32—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
- C07C235/34—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
- C07C237/20—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
- C07C237/22—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton having nitrogen atoms of amino groups bound to the carbon skeleton of the acid part, further acylated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
- C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C271/22—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
- C08G63/68—Polyesters containing atoms other than carbon, hydrogen and oxygen
- C08G63/685—Polyesters containing atoms other than carbon, hydrogen and oxygen containing nitrogen
- C08G63/6854—Polyesters containing atoms other than carbon, hydrogen and oxygen containing nitrogen derived from polycarboxylic acids and polyhydroxy compounds
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G69/00—Macromolecular compounds obtained by reactions forming a carboxylic amide link in the main chain of the macromolecule
- C08G69/44—Polyester-amides
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/930,146 US5216115A (en) | 1990-06-12 | 1992-08-13 | Polyarylate containing derivatives of the natural amino acid L-tyrosine |
| PCT/US1993/007676 WO1994004593A1 (en) | 1992-08-13 | 1993-08-13 | Polyarylates containing derivatives of the natural amino acid l-tyrosine |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69327057D1 true DE69327057D1 (de) | 1999-12-23 |
| DE69327057T2 DE69327057T2 (de) | 2000-04-13 |
Family
ID=25458979
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69327057T Expired - Lifetime DE69327057T2 (de) | 1992-08-13 | 1993-08-13 | Polyarylate, die derivate der natürlichen aminosäure l-tyrosin enthalten |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US5216115A (de) |
| EP (1) | EP0656026B1 (de) |
| JP (1) | JP3255365B2 (de) |
| AT (1) | ATE186741T1 (de) |
| AU (1) | AU670821B2 (de) |
| CA (1) | CA2140255C (de) |
| DE (1) | DE69327057T2 (de) |
| WO (1) | WO1994004593A1 (de) |
Families Citing this family (83)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5587507A (en) * | 1995-03-31 | 1996-12-24 | Rutgers, The State University | Synthesis of tyrosine derived diphenol monomers |
| USRE37160E1 (en) * | 1990-06-12 | 2001-05-01 | Rutgers, The State University | Synthesis of tyrosine derived diphenol monomers |
| US6515009B1 (en) | 1991-09-27 | 2003-02-04 | Neorx Corporation | Therapeutic inhibitor of vascular smooth muscle cells |
| US5811447A (en) | 1993-01-28 | 1998-09-22 | Neorx Corporation | Therapeutic inhibitor of vascular smooth muscle cells |
| US5658995A (en) * | 1995-11-27 | 1997-08-19 | Rutgers, The State University | Copolymers of tyrosine-based polycarbonate and poly(alkylene oxide) |
| US6120491A (en) * | 1997-11-07 | 2000-09-19 | The State University Rutgers | Biodegradable, anionic polymers derived from the amino acid L-tyrosine |
| US6048521A (en) * | 1997-11-07 | 2000-04-11 | Rutgers, The State University | Copolymers of tyrosine-based polyarlates and poly(alkylene oxides) |
| MXPA99007662A (es) * | 1997-02-18 | 2002-07-22 | Univ Rutgers | Monomeros derivados de hidroxiacidos, y polimeros preparados a partir de los mismos. |
| US6602497B1 (en) | 1997-11-07 | 2003-08-05 | Rutgers, The State University | Strictly alternating poly(alkylene oxide ether) copolymers |
| ATE307110T1 (de) * | 1997-11-07 | 2005-11-15 | Univ Rutgers | Strahlungsdurchlässiges polymeres biomaterial |
| US6623521B2 (en) | 1998-02-17 | 2003-09-23 | Md3, Inc. | Expandable stent with sliding and locking radial elements |
| AU761458B2 (en) * | 1998-04-13 | 2003-06-05 | Rutgers, The State University | The construction of copolymer libraries |
| US20070233272A1 (en) * | 1999-02-23 | 2007-10-04 | Boyce Todd M | Shaped load-bearing osteoimplant and methods of making same |
| US8133421B2 (en) * | 1999-02-23 | 2012-03-13 | Warsaw Orthopedic, Inc. | Methods of making shaped load-bearing osteoimplant |
| ATE266435T1 (de) * | 1999-04-16 | 2004-05-15 | Univ Rutgers | Poröse polymere stützgewebe für gewebetechnologie |
| US6103255A (en) | 1999-04-16 | 2000-08-15 | Rutgers, The State University | Porous polymer scaffolds for tissue engineering |
| US6899137B2 (en) * | 1999-06-28 | 2005-05-31 | California Institute Of Technology | Microfabricated elastomeric valve and pump systems |
| US20030170285A1 (en) * | 2001-11-13 | 2003-09-11 | Veazey William S. | Delivery of tissue engineering media |
| CA2822457C (en) | 2001-12-14 | 2016-03-08 | The University Of Wyoming | Methods and compositions for controlled resease of drugs |
| WO2003091337A1 (en) * | 2002-04-24 | 2003-11-06 | Rutgers, The State University | New polyarylates for drug delivery and tissue engineering |
| US20060182752A1 (en) * | 2003-05-15 | 2006-08-17 | Rutgers, The State University | Tri-block polymers for nanosphere-based drug or gene delivery |
| US8591951B2 (en) * | 2002-05-15 | 2013-11-26 | Joachim B. Kohn | Tri-block copolymers for nanosphere-based drug delivery |
| US6916868B2 (en) * | 2003-01-23 | 2005-07-12 | Integra Lifesciences Corporation | Selective modification of pendent functionalities of polymers |
| US8685367B2 (en) * | 2003-09-25 | 2014-04-01 | Rutgers, The State University of of New Jersey | Inherently radiopaque polymeric products for embolotherapy |
| US7368169B2 (en) * | 2003-12-01 | 2008-05-06 | Rutgers, The State University Of New Jersey | Hydrazide compounds with angiogenic activity |
| US7763065B2 (en) | 2004-07-21 | 2010-07-27 | Reva Medical, Inc. | Balloon expandable crush-recoverable stent device |
| WO2006023130A2 (en) * | 2004-08-12 | 2006-03-02 | Surmodics, Inc. | Biodegradable controlled release bioactive agent delivery device |
| WO2006020616A1 (en) * | 2004-08-13 | 2006-02-23 | Reva Medical, Inc. | Inherently radiopaque bioresorbable polymers for multiple uses |
| US20060034769A1 (en) * | 2004-08-13 | 2006-02-16 | Rutgers, The State University | Radiopaque polymeric stents |
| US8292944B2 (en) | 2004-12-17 | 2012-10-23 | Reva Medical, Inc. | Slide-and-lock stent |
| US9149378B2 (en) | 2005-08-02 | 2015-10-06 | Reva Medical, Inc. | Axially nested slide and lock expandable device |
| US7914574B2 (en) | 2005-08-02 | 2011-03-29 | Reva Medical, Inc. | Axially nested slide and lock expandable device |
| EP1949000A4 (de) | 2005-11-03 | 2010-08-04 | Tyrx Pharma Inc | Resorbierbare phenolische polymere |
| US8287914B2 (en) | 2006-01-12 | 2012-10-16 | Rutgers, The State University Of New Jersey | Biomimetic hydroxyapatite synthesis |
| US8315700B2 (en) * | 2006-02-08 | 2012-11-20 | Tyrx, Inc. | Preventing biofilm formation on implantable medical devices |
| EP2114298B1 (de) * | 2006-02-08 | 2022-10-19 | Medtronic, Inc. | Vorübergehend versteifte maschenprothesen |
| US8591531B2 (en) * | 2006-02-08 | 2013-11-26 | Tyrx, Inc. | Mesh pouches for implantable medical devices |
| AU2007236550B2 (en) * | 2006-04-07 | 2012-09-13 | The University Of Melbourne | Porous polymer structures |
| AU2007236549B2 (en) * | 2006-04-07 | 2011-11-03 | The University Of Melbourne | Porous polymer blend structures |
| EP2079491B1 (de) * | 2006-10-17 | 2013-02-27 | Reva Medical, Inc. | N-substituierte monomere und polymere |
| WO2010033640A1 (en) * | 2008-09-16 | 2010-03-25 | Rutgers, The State University Of New Jersey | Bioresorbable polymers synthesized from monomer analogs of natural metabolites |
| WO2008055038A2 (en) * | 2006-10-30 | 2008-05-08 | Rutgers, The State University | Electrospun matrices for delivery of hydrophilic and lidophilic compounds |
| US9023114B2 (en) * | 2006-11-06 | 2015-05-05 | Tyrx, Inc. | Resorbable pouches for implantable medical devices |
| MX2009004821A (es) | 2006-11-06 | 2009-11-23 | Tyrx Pharma Inc | Bolsas de malla para dispositivos medicos implantables. |
| ES2625134T3 (es) * | 2006-11-06 | 2017-07-18 | Tyrx, Inc. | Bolsas de mallas para dispositivos médicos implantables |
| KR101441709B1 (ko) * | 2006-11-30 | 2014-09-18 | 넥타르 테라퓨틱스 | 중합체 컨쥬게이트의 제조 방법 |
| US7704275B2 (en) | 2007-01-26 | 2010-04-27 | Reva Medical, Inc. | Circumferentially nested expandable device |
| CA2676841C (en) | 2007-01-31 | 2017-09-26 | Rutgers, The State University Of New Jersey | Controlled release of actives in skin |
| AU2008232682B2 (en) | 2007-03-29 | 2013-03-21 | Medtronic, Inc. | Biodegradable, polymer coverings for breast implants |
| CA2686214C (en) * | 2007-05-02 | 2016-02-23 | Tyrx Pharma, Inc. | Dihydroxybenzoate polymers and uses thereof |
| MX2009014279A (es) | 2007-06-21 | 2010-03-26 | Tyrx Pharma Inc | Cadenas laterales de ester de fenilo para incrementar la resortividad polimerica. |
| US7988721B2 (en) | 2007-11-30 | 2011-08-02 | Reva Medical, Inc. | Axially-radially nested expandable device |
| EP2296579B1 (de) | 2008-06-02 | 2019-11-06 | Rutgers, the State University of New Jersey | Aus gewebe gezüchtetes ersatz-knorpelgewebe |
| WO2010006249A1 (en) * | 2008-07-10 | 2010-01-14 | Tyrx Pharma, Inc. | Sustained release formulations of psychoactive drugs |
| US8652525B2 (en) * | 2008-07-10 | 2014-02-18 | Tyrx, Inc. | NSAID delivery from polyarylates |
| AU2009292949B2 (en) * | 2008-09-22 | 2014-10-09 | Medtronic, Inc. | Linear polyesteramides from aminophenolic esters |
| CA2737753C (en) | 2008-10-10 | 2017-03-14 | Reva Medical, Inc. | Expandable slide and lock stent |
| US8252887B2 (en) | 2008-10-11 | 2012-08-28 | Rutgers, The State University Of New Jersey | Biocompatible polymers for medical devices |
| US20100215716A1 (en) * | 2009-02-23 | 2010-08-26 | Biomet Manufacturing Corp. | Compositions and methods for coating orthopedic implants |
| JP5847706B2 (ja) | 2009-06-01 | 2016-01-27 | タイレックス・インコーポレイテッドＴｙｒｘ Ｉｎｃ． | 胸骨創感染症を予防するための組成物および方法 |
| US9839628B2 (en) | 2009-06-01 | 2017-12-12 | Tyrx, Inc. | Compositions and methods for preventing sternal wound infections |
| EP2459638B1 (de) | 2009-07-31 | 2017-09-27 | Rutgers, The State University of New Jersey | Monomere und daraus hergestellte phasengetrennte biokompatible polymerzusammensetzungen zur verwendung in der medizin |
| US8409279B2 (en) | 2009-10-01 | 2013-04-02 | Lipose Corporation | Breast implant implantation method and apparatus |
| JP6031355B2 (ja) | 2009-10-11 | 2016-11-24 | ラトガース，ザ ステート ユニバーシティ オブ ニュー ジャージー | 医療装置のための生体適合性重合体 |
| CA2795292A1 (en) | 2010-04-10 | 2011-10-13 | Reva Medical, Inc. | Expandable slide and lock stent |
| AU2011293344B2 (en) | 2010-08-25 | 2015-07-30 | Medtronic, Inc. | Novel medical device coatings |
| US8883861B2 (en) | 2010-11-01 | 2014-11-11 | Rutgers, The State University Of New Jersey | Iminic monomers and polymers thereof |
| JP6397190B2 (ja) | 2010-11-12 | 2018-09-26 | タイレックス・インコーポレイテッドＴｙｒｘ Ｉｎｃ． | 有効医薬品成分を含む固着装置 |
| US8961948B2 (en) | 2011-01-17 | 2015-02-24 | Rutgers, The State University Of New Jersey | Molecular surface design of tyrosine-derived polycarbonates for attachment of biomolecules |
| AU2012283875B2 (en) | 2011-07-20 | 2016-05-12 | Medtronic, Inc. | Drug eluting mesh to prevent infection of indwelling transdermal devices |
| US11472918B2 (en) | 2012-02-03 | 2022-10-18 | Rutgers, The State University Of New Jersey | Polymeric biomaterials derived from phenolic monomers and their medical uses |
| CA3069030C (en) | 2012-02-03 | 2021-11-16 | Rutgers, The State University Of New Jersey | Polymeric biomaterials derived from phenolic monomers and their medical uses |
| KR101417305B1 (ko) | 2012-07-23 | 2014-07-08 | 포항공과대학교 산학협력단 | 이온성 액체가 화학적으로 결합된 고분자 전해질막 및 이를 이용한 연료전지 |
| WO2014137454A1 (en) | 2013-03-07 | 2014-09-12 | Tyrx, Inc. | Methods and compositions to inhibit the assemblage of microbial cells irreversibly associated with surfaces of medical devices |
| SG11201507024VA (en) | 2013-03-08 | 2015-10-29 | Polyactiva Pty Ltd | Polymer conjugate for delivery of a bioactive agent |
| WO2014159337A1 (en) | 2013-03-14 | 2014-10-02 | Reva Medical, Inc. | Reduced - profile slide and lock stent |
| CN105682685B (zh) | 2013-08-07 | 2019-04-23 | 新泽西鲁特格斯州立大学 | 源自包含羟基酸和酚化合物的单体的聚合生物材料以及其医学用途 |
| CN105431178A (zh) | 2013-11-08 | 2016-03-23 | 泰尔克斯公司 | 用于防止手术切口部位感染的抗微生物组合物及方法 |
| WO2016103224A2 (en) | 2014-12-23 | 2016-06-30 | Rutgers, The State University Of New Jersey | Biocompatible iodinated diphenol monomers and polymers |
| US10774030B2 (en) | 2014-12-23 | 2020-09-15 | Rutgers, The State University Of New Jersey | Polymeric biomaterials derived from phenolic monomers and their medical uses |
| CA3053366A1 (en) | 2017-02-13 | 2018-08-16 | Rutgers, The State University Of New Jersey | Polymer filament reinforced scaffold for partial meniscus regeneration |
| WO2018156856A1 (en) | 2017-02-23 | 2018-08-30 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Stentless biopolymer heart valve replacement capable of living tissue regeneration |
| WO2018175234A1 (en) | 2017-03-20 | 2018-09-27 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Mandrel-less electrospinning processing method and system, and uses therefor |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2891929A (en) * | 1954-03-31 | 1959-06-23 | Eastman Kodak Co | Polyesters of a glycol, a dicarboxylic acid and an aminoacid |
| NL295096A (de) * | 1962-07-09 | |||
| BE689347A (de) * | 1965-12-09 | 1967-04-14 | Madan Ag | |
| US4356166A (en) * | 1978-12-08 | 1982-10-26 | University Of Utah | Time-release chemical delivery system |
| MX158102A (es) * | 1980-03-24 | 1989-01-09 | Sun Chemical Corp | Procedimiento mejorado para la obtencion de una resina de eteres de poliamida |
| US4579866A (en) * | 1984-05-29 | 1986-04-01 | Usv Pharmaceutical Corp. | Phenylacetamides as anti-allergy, anti-asthma and anti-inflammatory agents |
| US4868277A (en) * | 1988-08-18 | 1989-09-19 | The Dow Chemical Company | Polyamide resins with good toughness properties |
| US4999417A (en) * | 1989-03-30 | 1991-03-12 | Nova Pharmaceutical Corporation | Biodegradable polymer compositions |
| FR2649713B1 (fr) * | 1989-07-12 | 1991-10-18 | Atochem | Copolyesteramides semialiphatiques thermotropes et leur procede de preparation |
| US5015476A (en) * | 1989-08-11 | 1991-05-14 | Paravax, Inc. | Immunization implant and method |
| US5099060A (en) * | 1990-06-12 | 1992-03-24 | Rutgers, The State University Of New Jersey | Synthesis of amino acid-derived bioerodible polymers |
-
1992
- 1992-08-13 US US07/930,146 patent/US5216115A/en not_active Expired - Lifetime
-
1993
- 1993-08-13 DE DE69327057T patent/DE69327057T2/de not_active Expired - Lifetime
- 1993-08-13 AU AU50132/93A patent/AU670821B2/en not_active Expired
- 1993-08-13 WO PCT/US1993/007676 patent/WO1994004593A1/en active IP Right Grant
- 1993-08-13 JP JP50645394A patent/JP3255365B2/ja not_active Expired - Lifetime
- 1993-08-13 EP EP93920079A patent/EP0656026B1/de not_active Expired - Lifetime
- 1993-08-13 AT AT93920079T patent/ATE186741T1/de active
- 1993-08-13 CA CA002140255A patent/CA2140255C/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| JP3255365B2 (ja) | 2002-02-12 |
| US5216115A (en) | 1993-06-01 |
| EP0656026A4 (de) | 1996-01-10 |
| EP0656026B1 (de) | 1999-11-17 |
| ATE186741T1 (de) | 1999-12-15 |
| CA2140255A1 (en) | 1994-03-03 |
| AU5013293A (en) | 1994-03-15 |
| JPH08500387A (ja) | 1996-01-16 |
| DE69327057T2 (de) | 2000-04-13 |
| WO1994004593A1 (en) | 1994-03-03 |
| CA2140255C (en) | 1999-04-06 |
| AU670821B2 (en) | 1996-08-01 |
| EP0656026A1 (de) | 1995-06-07 |
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