DE69328762T2 - Zeitaufgelöste optische Sensorarrays und CCD-Kameras zur Frequenzbereich-Fluorimetrie und/oder Phosphorimetrie - Google Patents

Zeitaufgelöste optische Sensorarrays und CCD-Kameras zur Frequenzbereich-Fluorimetrie und/oder Phosphorimetrie

Info

Publication number
DE69328762T2
DE69328762T2 DE69328762T DE69328762T DE69328762T2 DE 69328762 T2 DE69328762 T2 DE 69328762T2 DE 69328762 T DE69328762 T DE 69328762T DE 69328762 T DE69328762 T DE 69328762T DE 69328762 T2 DE69328762 T2 DE 69328762T2
Authority
DE
Germany
Prior art keywords
frequency
signal
phosphorimetry
radiation
frequency domain
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69328762T
Other languages
English (en)
Other versions
DE69328762D1 (de
Inventor
Enrico Gratton
Ven Martin Vande
Beniamino Barbieri
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
I.S.S. (USA) INC., CHAMPAIGN, ILL., US
Original Assignee
Enrico Gratton
Ven Martin Vande
Beniamino Barbieri
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Enrico Gratton, Ven Martin Vande, Beniamino Barbieri filed Critical Enrico Gratton
Application granted granted Critical
Publication of DE69328762D1 publication Critical patent/DE69328762D1/de
Publication of DE69328762T2 publication Critical patent/DE69328762T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6408—Fluorescence; Phosphorescence with measurement of decay time, time resolved fluorescence
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/28—Investigating the spectrum
    • G01J3/44—Raman spectrometry; Scattering spectrometry ; Fluorescence spectrometry
    • G01J3/4406—Fluorescence spectrometry
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N2021/1765—Method using an image detector and processing of image signal
    • G01N2021/177—Detector of the video camera type
    • G01N2021/1772—Array detector
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N2021/1789—Time resolved
DE69328762T 1992-12-01 1993-11-17 Zeitaufgelöste optische Sensorarrays und CCD-Kameras zur Frequenzbereich-Fluorimetrie und/oder Phosphorimetrie Expired - Fee Related DE69328762T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/983,829 US5323010A (en) 1992-12-01 1992-12-01 Time resolved optical array detectors and CCD cameras for frequency domain fluorometry and/or phosphorimetry

Publications (2)

Publication Number Publication Date
DE69328762D1 DE69328762D1 (de) 2000-07-06
DE69328762T2 true DE69328762T2 (de) 2001-02-22

Family

ID=25530126

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69328762T Expired - Fee Related DE69328762T2 (de) 1992-12-01 1993-11-17 Zeitaufgelöste optische Sensorarrays und CCD-Kameras zur Frequenzbereich-Fluorimetrie und/oder Phosphorimetrie

Country Status (6)

Country Link
US (1) US5323010A (de)
EP (1) EP0600633B1 (de)
JP (1) JPH07306140A (de)
AT (1) ATE193597T1 (de)
CA (1) CA2103077A1 (de)
DE (1) DE69328762T2 (de)

Cited By (2)

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DE102010019095A1 (de) * 2010-04-30 2011-11-03 Deutsches Zentrum für Luft- und Raumfahrt e.V. Verfahren und Vorrichtung zur Fluoreszenzlebensdauermessung
DE102022122092A1 (de) 2022-08-31 2024-02-29 Pyroscience Gmbh Referenz-Messung

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US6300638B1 (en) 1998-11-12 2001-10-09 Calspan Srl Corporation Modular probe for total internal reflection fluorescence spectroscopy
JP2000283960A (ja) * 1999-03-31 2000-10-13 Shimadzu Corp マイクロチップ電気泳動装置
US6690098B1 (en) * 2000-01-31 2004-02-10 Litton Systems, Inc. Method and system for gating a power supply in a radiation detector
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US6673626B1 (en) 2000-10-31 2004-01-06 Science & Technology Corporation University Of New Mexico Optoelectronic circuit for detecting changes in fluorescence lifetime
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EP1428003A2 (de) * 2001-09-19 2004-06-16 Joule Microsystems Canada Inc. Spektrometer mit adaptivfilter
US7041986B2 (en) * 2002-03-14 2006-05-09 University Of Maryland Baltimore County Device for discrimination of fluorescence lifetimes and uses therefor
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US7274028B2 (en) * 2005-07-14 2007-09-25 The Boeing Company Characterizing fluorescent and/or phosphorescent materials
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US7988688B2 (en) * 2006-09-21 2011-08-02 Lockheed Martin Corporation Miniature apparatus and method for optical stimulation of nerves and other animal tissue
US8475506B1 (en) 2007-08-13 2013-07-02 Lockheed Martin Corporation VCSEL array stimulator apparatus and method for light stimulation of bodily tissues
US8709078B1 (en) 2011-08-03 2014-04-29 Lockheed Martin Corporation Ocular implant with substantially constant retinal spacing for transmission of nerve-stimulation light
US8945197B1 (en) 2005-10-24 2015-02-03 Lockheed Martin Corporation Sight-restoring visual prosthetic and method using infrared nerve-stimulation light
US8792978B2 (en) 2010-05-28 2014-07-29 Lockheed Martin Corporation Laser-based nerve stimulators for, E.G., hearing restoration in cochlear prostheses and method
US8929973B1 (en) 2005-10-24 2015-01-06 Lockheed Martin Corporation Apparatus and method for characterizing optical sources used with human and animal tissues
US8744570B2 (en) 2009-01-23 2014-06-03 Lockheed Martin Corporation Optical stimulation of the brainstem and/or midbrain, including auditory areas
US8996131B1 (en) 2006-09-28 2015-03-31 Lockheed Martin Corporation Apparatus and method for managing chronic pain with infrared light sources and heat
US8160696B2 (en) 2008-10-03 2012-04-17 Lockheed Martin Corporation Nerve stimulator and method using simultaneous electrical and optical signals
US8498699B2 (en) * 2008-10-03 2013-07-30 Lockheed Martin Company Method and nerve stimulator using simultaneous electrical and optical signals
US7883536B1 (en) 2007-01-19 2011-02-08 Lockheed Martin Corporation Hybrid optical-electrical probes
EP2215441A2 (de) * 2007-10-25 2010-08-11 The Research Foundation of the State University of New York Einzelphotonen-spektrometer
US8834545B2 (en) 2011-07-22 2014-09-16 Lockheed Martin Corporation Optical-stimulation cochlear implant with electrode(s) at the apical end for electrical stimulation of apical spiral ganglion cells of the cochlea
US20090289833A1 (en) * 2008-05-23 2009-11-26 Johnson Paul A Sparse array millimeter wave imaging system
US20100016732A1 (en) * 2008-07-17 2010-01-21 Lockheed Martin Corporation Apparatus and method for neural-signal capture to drive neuroprostheses or control bodily function
KR20110127170A (ko) * 2009-02-10 2011-11-24 미쯔이 죠센 가부시키가이샤 형광 검출 장치 및 형광 검출 방법
US8330123B2 (en) * 2010-01-28 2012-12-11 I.S.S. (Usa), Inc. System and method for digital parallel frequency fluorometry
US7884933B1 (en) 2010-05-05 2011-02-08 Revolutionary Business Concepts, Inc. Apparatus and method for determining analyte concentrations
AU2011323310A1 (en) 2010-11-03 2013-06-13 University Of Washington Through Its Center For Commercialization Determination of tissue oxygenation in vivo
US9222888B2 (en) * 2012-04-03 2015-12-29 Ut-Battelle, Llc Pulse amplitude modulated chlorophyll fluorometer
US11016179B2 (en) * 2017-12-03 2021-05-25 Munro Design & Technologies, Llc Digital image processing systems for three-dimensional imaging systems with image intensifiers and methods thereof

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US4840485A (en) * 1986-12-17 1989-06-20 I.S.S. (U.S.A.) Inc. Frequency domain cross-correlation fluorometry with phase-locked loop frequency synthesizers
US4937457A (en) * 1989-02-10 1990-06-26 Slm Instruments, Inc. Picosecond multi-harmonic fourier fluorometer
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US5212386A (en) * 1991-12-13 1993-05-18 I.S.S. (U.S.A.) Inc. High speed cross-correlation frequency domain fluorometry-phosphorimetry

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102010019095A1 (de) * 2010-04-30 2011-11-03 Deutsches Zentrum für Luft- und Raumfahrt e.V. Verfahren und Vorrichtung zur Fluoreszenzlebensdauermessung
US8487275B2 (en) 2010-04-30 2013-07-16 Deutsches Zentrum fur-Luft-und Raumfahrt e.V. Method and a device for measuring fluorescence lifetime
DE102010019095B4 (de) * 2010-04-30 2016-12-08 Deutsches Zentrum für Luft- und Raumfahrt e.V. Verfahren und Vorrichtung zur Fluoreszenzlebensdauermessung
DE102022122092A1 (de) 2022-08-31 2024-02-29 Pyroscience Gmbh Referenz-Messung

Also Published As

Publication number Publication date
CA2103077A1 (en) 1994-06-02
EP0600633B1 (de) 2000-05-31
ATE193597T1 (de) 2000-06-15
EP0600633A2 (de) 1994-06-08
EP0600633A3 (en) 1994-06-15
DE69328762D1 (de) 2000-07-06
JPH07306140A (ja) 1995-11-21
US5323010A (en) 1994-06-21

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Legal Events

Date Code Title Description
8332 No legal effect for de
8370 Indication related to discontinuation of the patent is to be deleted
8327 Change in the person/name/address of the patent owner

Owner name: I.S.S. (USA) INC., CHAMPAIGN, ILL., US

8381 Inventor (new situation)

Free format text: GRATTON, ENRICO, URBANA, ILL., US VANDE VEN, MARTIN, CHAMPAIGN, ILL., US BARBIERI, BENIAMINO, CHAMPAIGN, ILL., US

8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee