DE69332275D1 - Verfahren und zusammensetzungen auf der basis eines polymers (poloxamer) zur zellregeneration - Google Patents

Verfahren und zusammensetzungen auf der basis eines polymers (poloxamer) zur zellregeneration

Info

Publication number
DE69332275D1
DE69332275D1 DE69332275T DE69332275T DE69332275D1 DE 69332275 D1 DE69332275 D1 DE 69332275D1 DE 69332275 T DE69332275 T DE 69332275T DE 69332275 T DE69332275 T DE 69332275T DE 69332275 D1 DE69332275 D1 DE 69332275D1
Authority
DE
Germany
Prior art keywords
surface active
disclosed
compositions
methods
active copolymer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69332275T
Other languages
English (en)
Other versions
DE69332275T2 (de
Inventor
Raphael C Lee
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Arch Development Corp
Original Assignee
Arch Development Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Arch Development Corp filed Critical Arch Development Corp
Application granted granted Critical
Publication of DE69332275D1 publication Critical patent/DE69332275D1/de
Publication of DE69332275T2 publication Critical patent/DE69332275T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/785—Polymers containing nitrogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/765—Polymers containing oxygen
    • A61K31/77—Polymers containing oxygen of oxiranes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S424/00—Drug, bio-affecting and body treating compositions
    • Y10S424/13—Burn treatment
DE69332275T 1992-02-13 1993-02-12 Verfahren und zusammensetzungen auf der basis eines polymers (poloxamer) zur zellregeneration Expired - Lifetime DE69332275T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/835,271 US5470568A (en) 1992-02-13 1992-02-13 Methods and compositions of a polymer (poloxamer) for cell repair
PCT/US1993/001327 WO1993015745A1 (en) 1992-02-13 1993-02-12 Methods and compositions of a polymer (poloxamer) for cell repair

Publications (2)

Publication Number Publication Date
DE69332275D1 true DE69332275D1 (de) 2002-10-10
DE69332275T2 DE69332275T2 (de) 2003-04-17

Family

ID=25269083

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69332275T Expired - Lifetime DE69332275T2 (de) 1992-02-13 1993-02-12 Verfahren und zusammensetzungen auf der basis eines polymers (poloxamer) zur zellregeneration

Country Status (7)

Country Link
US (1) US5470568A (de)
EP (1) EP0683669B1 (de)
AT (1) ATE223222T1 (de)
AU (1) AU3667293A (de)
DE (1) DE69332275T2 (de)
DK (1) DK0683669T3 (de)
WO (1) WO1993015745A1 (de)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020123476A1 (en) * 1991-03-19 2002-09-05 Emanuele R. Martin Therapeutic delivery compositions and methods of use thereof
US7202225B1 (en) * 1993-10-15 2007-04-10 Emanuele R Martin Therapeutic delivery compositions and methods of use thereof
US6153193A (en) * 1993-04-28 2000-11-28 Supratek Pharma Inc. Compositions for targeting biological agents
US6093391A (en) * 1992-10-08 2000-07-25 Supratek Pharma, Inc. Peptide copolymer compositions
US6277410B1 (en) 1992-10-08 2001-08-21 Supratek Pharma Inc. Copolymer compositions for oral delivery
GB2281697A (en) * 1993-09-14 1995-03-15 Euro Celtique Sa Laxative compositions in capsules
US5608520A (en) * 1994-07-11 1997-03-04 The United States Of America As Represented By He Department Of Energy Plasma emission spectroscopy method of tumor therapy
GB9417742D0 (en) * 1994-09-03 1994-10-19 Univ Nottingham Macrophage stimulating composition
US6353055B1 (en) 1994-11-18 2002-03-05 Supratek Pharma Inc. Polynucleotide compositions
US6221959B1 (en) 1994-11-18 2001-04-24 Supratek Pharma, Inc. Polynucleotide compositions
US6359054B1 (en) 1994-11-18 2002-03-19 Supratek Pharma Inc. Polynucleotide compositions for intramuscular administration
US6040295A (en) 1995-01-13 2000-03-21 Genemedicine, Inc. Formulated nucleic acid compositions and methods of administering the same for gene therapy
DE19537494C2 (de) * 1995-09-25 1997-10-02 Desitin Arzneimittel Gmbh Kreatin zum Schutz von neuralem Gewebe
US6323549B1 (en) * 1996-08-29 2001-11-27 L. Pierre deRochemont Ceramic composite wiring structures for semiconductor devices and method of manufacture
WO1998013069A2 (en) 1996-09-09 1998-04-02 Supratek Pharma, Inc. Fluorinated copolymeric pharmaceutical adjuncts
WO2000009732A1 (en) * 1998-08-13 2000-02-24 Warner-Lambert Company Electroporation buffer with cryprotective capabilities
US7582680B1 (en) 1998-11-12 2009-09-01 Purdue Research Foundation Methods and compositions for treating mammalian spinal cord injuries
EP1309904A4 (de) * 2000-03-03 2006-03-29 Valentis Inc Verbesserte poloxamer- und polyoaminverbindungen zur nukleinsäureeinbringung
EP1278551A2 (de) * 2000-04-21 2003-01-29 Vical Incorporated Zusammensetzungen und verfahren zur (in vivo) verabreichung der auf polynukleotiden-basierenden therapeutika
WO2001083698A2 (en) * 2000-04-28 2001-11-08 Supratek Pharma, Inc. Compositions and methods for inducing activation of dendritic cells
MY128134A (en) * 2000-09-28 2007-01-31 Novartis Ag Compositions and methods for cleaning contact lenses
US20040009940A1 (en) * 2000-10-20 2004-01-15 Coleman Michael E. Gene delivery formulations and methods for treatment of ischemic conditions
CA2445612C (en) 2001-04-24 2011-10-25 Purdue Research Foundation Methods and compositions for treating mammalian nerve tissue injuries
CA2472170A1 (en) * 2001-12-28 2003-07-24 Supratek Pharma Inc. Pharmaceutical compositions comprising polyanionic polymers and amphiphilic block copolymers and methods of use thereof to improve gene expression
FR2835749B1 (fr) * 2002-02-08 2006-04-14 Inst Nat Sante Rech Med Composition pharmaceutique ameliorant le transfert de gene in vivo
KR101198550B1 (ko) 2003-03-24 2012-11-06 플루로메드, 인코포레이티드 역성 열감응 중합체를 사용하는 일시적인 색전화
WO2005046438A2 (en) * 2003-11-06 2005-05-26 Pluromed, Inc. Internal clamp for surgical procedures
US20090155200A1 (en) * 2004-04-20 2009-06-18 Jay Gregory D Methods of promoting cartilage healing or cartilage integration
WO2006044738A2 (en) * 2004-10-18 2006-04-27 Maroon Biotech Corporation Methods and compositions for treatment of free radical injury
WO2008034082A2 (en) * 2006-09-15 2008-03-20 Maroon Biotech, Corporation Method of using amphiphilic multiblock copolymers in food
EP3170396A1 (de) 2007-02-19 2017-05-24 Plurogen Therapeutics, Inc. Zusammensetzungen zur bearbeitung von biofolien und verfahren zur verwendung davon
BRPI0919919A2 (pt) 2008-10-21 2017-05-30 Massachusetts Gen Hospital transplante celular
WO2012019103A2 (en) 2010-08-06 2012-02-09 The General Hospital Corporation D/B/A System and apparatus for cell treatment
US20160131634A1 (en) * 2013-05-29 2016-05-12 Biogen Ma Inc. Methods of evaluating cell culture additives
WO2016118644A1 (en) * 2015-01-20 2016-07-28 Plurogen Therapeutics, Llc Compositions and methods of treating microbes
JP2023532915A (ja) * 2020-07-09 2023-08-01 ムスク・ファウンデイション・フォー・リサーチ・ディベロップメント 傷害から細胞を保護する方法
US20240024354A1 (en) * 2020-09-04 2024-01-25 The University Of Chicago Materials and methods of treating viral infection with amphiphilic block copolymers

Family Cites Families (53)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US29909A (en) * 1860-09-04 Ebenezer G Pomeroy Improved method of converting iron into steel
US2674619A (en) * 1953-10-19 1954-04-06 Wyandotte Chemicals Corp Polyoxyalkylene compounds
US2854378A (en) * 1955-12-08 1958-09-30 Bristol Lab Inc Tetracycline suppository
GB840155A (en) * 1958-01-30 1960-07-06 Louis Lafon Improvements in or relating to pharmaceutical compositions
US3089818A (en) * 1960-06-02 1963-05-14 Baxter Laboratories Inc Water dispersible antibiotics
GB983130A (en) * 1962-08-06 1965-02-10 Mundipharma Ag Improvements in preparations for the removal of wax from the ear
US3140232A (en) * 1962-12-19 1964-07-07 Pfizer & Co C Color stabilization of tetracycline compositions with polypropylene glycols
US3740421A (en) * 1966-09-19 1973-06-19 Basf Wyandotte Corp Polyoxyethylene-polyoxypropylene aqueous gels
US3639575A (en) * 1968-06-19 1972-02-01 Basf Wyandotte Corp Silver ion gel compositions and method of using the same
AU418761B2 (en) * 1968-09-19 1971-11-06 Phosiological salt solutions of ethylene oxide-polypropylene glycol condensation products
US3641240A (en) * 1968-09-27 1972-02-08 Wyandotte Chemicals Corp Method for the treatment of an embolus or thrombus
US3590125A (en) * 1969-10-10 1971-06-29 Wyandotte Chemicals Corp Physiological salt solutions of ethylene oxide-polypropylene glycol condensation products as blood plasma substitutes
US3577522A (en) * 1969-10-10 1971-05-04 Wyandotte Chemicals Corp Methods for the treatment of shock with ethylene oxide-polypropylene glycol condensates as blood plasma substitutes
US3980772A (en) * 1969-12-02 1976-09-14 Baxter Laboratories, Inc. Methods of dissolving blood clots and the like with streptokinase chemically bonded to a carbohydrate matrix
US3867521A (en) * 1970-08-26 1975-02-18 Scherer Corp R P Method for absorption of drugs
US3956259A (en) * 1973-01-30 1976-05-11 Baxter Laboratories, Inc. Fractionation of blood using block copolymer of ethylene oxide and polyoxypropylene polymer to recover fraction suitable for organ perfusate
US4073886A (en) * 1973-01-30 1978-02-14 Baxter Travenol Laboratories, Inc. Blood fractionation process using block copolymers of ethylene oxide and polyoxypropylene
US4179337A (en) * 1973-07-20 1979-12-18 Davis Frank F Non-immunogenic polypeptides
US3997458A (en) * 1974-04-12 1976-12-14 Deknatel, Incorporated Method of cleansing contaminated wounds and surgical scrub solutions for same
US4105650A (en) * 1975-04-11 1978-08-08 Edward Shanbrom, Inc. Method of preserving blood plasma i
US4100271A (en) * 1976-02-26 1978-07-11 Cooper Laboratories, Inc. Clear, water-miscible, liquid pharmaceutical vehicles and compositions which gel at body temperature for drug delivery to mucous membranes
US4305922A (en) * 1978-10-04 1981-12-15 University Patents, Inc. Labeling proteins with 99m-Tc by ligand exchange
US4186253A (en) * 1978-10-10 1980-01-29 The Green Cross Corporation Perfusate for preserving organ to be transplanted and preserving method
US4395393A (en) * 1981-08-10 1983-07-26 Basf Wyandotte Corporation Artificial blood emulsifiers
US4407790A (en) * 1981-09-25 1983-10-04 Economics Laboratory, Inc. Method of controlling bloat using nonionic surfactants
CA1244774A (en) * 1983-11-09 1988-11-15 Thomas Jefferson University Medium for storing blood platelets
US4600652A (en) * 1985-04-01 1986-07-15 Warner-Lambert Company Permanently bonded antithrombogenic polyurethane surface
JPH084504B2 (ja) * 1985-04-26 1996-01-24 味の素株式会社 安定化ス−パ−オキサイドジスムタ−ゼ
WO1987006831A1 (en) * 1986-05-15 1987-11-19 Emory University Composition and method for treating a thrombus and embolus
US5032394A (en) * 1986-05-15 1991-07-16 Emory University Method of treating burns
US4897263A (en) * 1986-05-15 1990-01-30 Emory University Methods and compositions for treatment of pathological hydrophobic interactions in biological fluids
US4937070A (en) * 1986-05-15 1990-06-26 Emory University Methods and compositions for treatment of pathological hydrophobic interactions in biological fluids
US4879109A (en) * 1986-05-15 1989-11-07 Emory University Method for treating burns
US5017370A (en) * 1986-05-15 1991-05-21 Emory University Improved method of performing angioplasty procedures
US5064643A (en) * 1986-05-15 1991-11-12 Emory University Method for treating sickle cell disease
US5047236A (en) * 1986-05-15 1991-09-10 Emory University Method of treating stroke
US4801452A (en) * 1986-05-15 1989-01-31 Hunter Robert L Fibrinolytic composition
US4873083A (en) * 1986-05-15 1989-10-10 Emory University Fibrinolytic composition
US5039520A (en) * 1986-05-15 1991-08-13 Emory University Plasma extender
US4837014A (en) * 1986-05-15 1989-06-06 Emory University An improved method of treating sickle cell anemia
US5089260A (en) * 1986-05-15 1992-02-18 Emory University Method of treating ischemic tissue
US5028599A (en) * 1986-05-15 1991-07-02 Emory University Method of treating mycardial damage
WO1987006836A1 (en) * 1986-05-15 1987-11-19 Emory University Fibrinolytic composition
US5080894A (en) * 1986-05-15 1992-01-14 Emory University Method and composition for reducing tissue damage
US5078995A (en) * 1986-05-15 1992-01-07 Emory University Fibrionolytic composition
US5030448A (en) * 1986-05-15 1991-07-09 Emory University Method of delivering drugs to damaged or diseased tissue
US5152979A (en) * 1986-05-15 1992-10-06 Emory University Method for treating vascular obstructions caused by abnormal cells
US5071649A (en) * 1986-05-15 1991-12-10 Emory University Method of preventing blockage in catheters
US5041288A (en) * 1986-05-15 1991-08-20 Emory University Method of treating tissue damaged by reperfusion injury
US5045468A (en) * 1986-12-12 1991-09-03 Cell Enterprises, Inc. Protein-free culture medium which promotes hybridoma growth
US5075333A (en) * 1987-08-19 1991-12-24 Hoffmann-La Roche Inc. Tetrahydronaphthalene and indane compounds useful for reversing the photo-damage in sun-exposed skin
US5002965A (en) * 1989-05-09 1991-03-26 Societe De Conseils De Recherches Et D'applications Scientifiques (S.C.R.A.S.) Use of ginkgolides to prevent reperfusion injury in organ transplantation
US4997664A (en) * 1989-09-05 1991-03-05 Bryan Foods, Inc. Method for packaging food products

Also Published As

Publication number Publication date
ATE223222T1 (de) 2002-09-15
AU3667293A (en) 1993-09-03
DE69332275T2 (de) 2003-04-17
EP0683669A4 (de) 1995-08-11
US5470568A (en) 1995-11-28
DK0683669T3 (da) 2003-01-06
WO1993015745A1 (en) 1993-08-19
EP0683669A1 (de) 1995-11-29
EP0683669B1 (de) 2002-09-04

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