DE69333286D1 - Eine thrombin-blutfraktion zur verwendung in einem medizinischen verfahren - Google Patents

Eine thrombin-blutfraktion zur verwendung in einem medizinischen verfahren

Info

Publication number
DE69333286D1
DE69333286D1 DE69333286T DE69333286T DE69333286D1 DE 69333286 D1 DE69333286 D1 DE 69333286D1 DE 69333286 T DE69333286 T DE 69333286T DE 69333286 T DE69333286 T DE 69333286T DE 69333286 D1 DE69333286 D1 DE 69333286D1
Authority
DE
Germany
Prior art keywords
thrombin
blood fraction
medical process
thrombin blood
animal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69333286T
Other languages
English (en)
Other versions
DE69333286T2 (de
Inventor
Stewart Ant Cederholm-Williams
Ulla Weis-Fogh
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ER Squibb and Sons LLC
Original Assignee
ER Squibb and Sons LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ER Squibb and Sons LLC filed Critical ER Squibb and Sons LLC
Publication of DE69333286D1 publication Critical patent/DE69333286D1/de
Application granted granted Critical
Publication of DE69333286T2 publication Critical patent/DE69333286T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424Serine endopeptidases (3.4.21)
    • C12N9/6429Thrombin (3.4.21.5)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14Blood; Artificial blood
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/04Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
    • A61L24/10Polypeptides; Proteins
    • A61L24/106Fibrin; Fibrinogen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y304/00Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21Serine endopeptidases (3.4.21)
    • C12Y304/21005Thrombin (3.4.21.5)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/70Enzymes
DE69333286T 1992-06-24 1993-06-24 Eine thrombin-blutfraktion zur verwendung in einem medizinischen verfahren Expired - Fee Related DE69333286T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DK83092 1992-06-24
DK92830A DK83092D0 (da) 1992-06-24 1992-06-24 Fremgangsmaade til udvinding af thrombin
PCT/GB1993/001323 WO1994000566A1 (en) 1992-06-24 1993-06-24 A thrombin blood fraction for use in a medical procedure

Publications (2)

Publication Number Publication Date
DE69333286D1 true DE69333286D1 (de) 2003-12-11
DE69333286T2 DE69333286T2 (de) 2004-08-19

Family

ID=8098037

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69333286T Expired - Fee Related DE69333286T2 (de) 1992-06-24 1993-06-24 Eine thrombin-blutfraktion zur verwendung in einem medizinischen verfahren

Country Status (12)

Country Link
US (1) US5795571A (de)
EP (1) EP0654078B1 (de)
JP (1) JPH07508275A (de)
AT (1) ATE253631T1 (de)
AU (1) AU675650B2 (de)
CA (1) CA2131316C (de)
DE (1) DE69333286T2 (de)
DK (2) DK83092D0 (de)
FI (1) FI946004A0 (de)
NO (1) NO944997D0 (de)
NZ (2) NZ299131A (de)
WO (1) WO1994000566A1 (de)

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Also Published As

Publication number Publication date
NZ253294A (en) 1999-05-28
EP0654078B1 (de) 2003-11-05
US5795571A (en) 1998-08-18
DK0654078T3 (da) 2004-01-26
JPH07508275A (ja) 1995-09-14
NZ299131A (en) 2001-07-27
WO1994000566A1 (en) 1994-01-06
ATE253631T1 (de) 2003-11-15
EP0654078A1 (de) 1995-05-24
NO944997L (no) 1994-12-23
DK83092D0 (da) 1992-06-24
CA2131316C (en) 2002-03-19
FI946004A (fi) 1994-12-21
AU675650B2 (en) 1997-02-13
DE69333286T2 (de) 2004-08-19
CA2131316A1 (en) 1994-01-06
AU4350193A (en) 1994-01-24
NO944997D0 (no) 1994-12-23
FI946004A0 (fi) 1994-12-21

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