DE69425838T2 - Nicht-oxydierendes, medizinisches Polymerimplantat - Google Patents

Nicht-oxydierendes, medizinisches Polymerimplantat

Info

Publication number
DE69425838T2
DE69425838T2 DE69425838T DE69425838T DE69425838T2 DE 69425838 T2 DE69425838 T2 DE 69425838T2 DE 69425838 T DE69425838 T DE 69425838T DE 69425838 T DE69425838 T DE 69425838T DE 69425838 T2 DE69425838 T2 DE 69425838T2
Authority
DE
Germany
Prior art keywords
molecular weight
polyethylene
medical implant
average molecular
high molecular
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69425838T
Other languages
English (en)
Other versions
DE69425838D1 (de
Inventor
Deh Chuan Sun
Casper F Stark
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Howmedica Osteonics Corp
Original Assignee
Stryker Technologies Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22092961&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69425838(T2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Stryker Technologies Corp filed Critical Stryker Technologies Corp
Publication of DE69425838D1 publication Critical patent/DE69425838D1/de
Application granted granted Critical
Publication of DE69425838T2 publication Critical patent/DE69425838T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/02—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using physical phenomena
    • A61L2/08—Radiation
    • A61L2/081—Gamma radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42—Use of materials characterised by their function or physical properties
    • A61L15/60—Liquid-swellable gel-forming materials, e.g. super-absorbents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/02—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using physical phenomena
    • A61L2/08—Radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/02—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using physical phenomena
    • A61L2/08—Radiation
    • A61L2/082—X-rays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/02—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using physical phenomena
    • A61L2/08—Radiation
    • A61L2/087—Particle radiation, e.g. electron-beam, alpha or beta radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/16—Macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
    • A61L29/04—Macromolecular materials
    • A61L29/041—Macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04—Macromolecular materials
    • A61L31/048—Macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C35/00—Heating, cooling or curing, e.g. crosslinking or vulcanising; Apparatus therefor
    • B29C35/02—Heating or curing, e.g. crosslinking or vulcanizing during moulding, e.g. in a mould
    • B29C35/08—Heating or curing, e.g. crosslinking or vulcanizing during moulding, e.g. in a mould by wave energy or particle radiation
    • B29C35/0805—Heating or curing, e.g. crosslinking or vulcanizing during moulding, e.g. in a mould by wave energy or particle radiation using electromagnetic radiation
    • B29C2035/085—Heating or curing, e.g. crosslinking or vulcanizing during moulding, e.g. in a mould by wave energy or particle radiation using electromagnetic radiation using gamma-ray
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C35/00—Heating, cooling or curing, e.g. crosslinking or vulcanising; Apparatus therefor
    • B29C35/02—Heating or curing, e.g. crosslinking or vulcanizing during moulding, e.g. in a mould
    • B29C35/08—Heating or curing, e.g. crosslinking or vulcanizing during moulding, e.g. in a mould by wave energy or particle radiation
    • B29C35/0805—Heating or curing, e.g. crosslinking or vulcanizing during moulding, e.g. in a mould by wave energy or particle radiation using electromagnetic radiation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C43/00—Compression moulding, i.e. applying external pressure to flow the moulding material; Apparatus therefor
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C43/00—Compression moulding, i.e. applying external pressure to flow the moulding material; Apparatus therefor
    • B29C43/02—Compression moulding, i.e. applying external pressure to flow the moulding material; Apparatus therefor of articles of definite length, i.e. discrete articles
    • B29C43/16—Forging
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29K—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES B29B, B29C OR B29D, RELATING TO MOULDING MATERIALS OR TO MATERIALS FOR MOULDS, REINFORCEMENTS, FILLERS OR PREFORMED PARTS, e.g. INSERTS
    • B29K2023/00—Use of polyalkenes or derivatives thereof as moulding material
    • B29K2023/04—Polymers of ethylene
    • B29K2023/06—PE, i.e. polyethylene
    • B29K2023/0658—PE, i.e. polyethylene characterised by its molecular weight
    • B29K2023/0683—UHMWPE, i.e. ultra high molecular weight polyethylene
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29K—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES B29B, B29C OR B29D, RELATING TO MOULDING MATERIALS OR TO MATERIALS FOR MOULDS, REINFORCEMENTS, FILLERS OR PREFORMED PARTS, e.g. INSERTS
    • B29K2105/00—Condition, form or state of moulded material or of the material to be shaped
    • B29K2105/25—Solid
    • B29K2105/253—Preform
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29K—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES B29B, B29C OR B29D, RELATING TO MOULDING MATERIALS OR TO MATERIALS FOR MOULDS, REINFORCEMENTS, FILLERS OR PREFORMED PARTS, e.g. INSERTS
    • B29K2995/00—Properties of moulding materials, reinforcements, fillers, preformed parts or moulds
    • B29K2995/0037—Other properties
    • B29K2995/0087—Wear resistance
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29K—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES B29B, B29C OR B29D, RELATING TO MOULDING MATERIALS OR TO MATERIALS FOR MOULDS, REINFORCEMENTS, FILLERS OR PREFORMED PARTS, e.g. INSERTS
    • B29K2995/00—Properties of moulding materials, reinforcements, fillers, preformed parts or moulds
    • B29K2995/0037—Other properties
    • B29K2995/0089—Impact strength or toughness
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29L—INDEXING SCHEME ASSOCIATED WITH SUBCLASS B29C, RELATING TO PARTICULAR ARTICLES
    • B29L2031/00—Other particular articles
    • B29L2031/753—Medical equipment; Accessories therefor
    • B29L2031/7532—Artificial members, protheses
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S522/00—Synthetic resins or natural rubbers -- part of the class 520 series
    • Y10S522/915—Synthetic resins or natural rubbers -- part of the class 520 series involving inert gas, steam, nitrogen gas, or carbon dioxide
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S525/00—Synthetic resins or natural rubbers -- part of the class 520 series
    • Y10S525/937—Utility as body contact e.g. implant, contact lens or I.U.D.
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S623/00—Prosthesis, i.e. artificial body members, parts thereof, or aids and accessories therefor
    • Y10S623/901—Method of manufacturing prosthetic device

Landscapes

  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Medicinal Chemistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Dispersion Chemistry (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Surgery (AREA)
  • Vascular Medicine (AREA)
  • Materials For Medical Uses (AREA)
  • Treatments Of Macromolecular Shaped Articles (AREA)
  • Polyesters Or Polycarbonates (AREA)
DE69425838T 1993-06-01 1994-04-26 Nicht-oxydierendes, medizinisches Polymerimplantat Expired - Lifetime DE69425838T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/070,074 US5414049A (en) 1993-06-01 1993-06-01 Non-oxidizing polymeric medical implant

Publications (2)

Publication Number Publication Date
DE69425838D1 DE69425838D1 (de) 2000-10-12
DE69425838T2 true DE69425838T2 (de) 2001-04-12

Family

ID=22092961

Family Applications (4)

Application Number Title Priority Date Filing Date
DE69434462T Expired - Lifetime DE69434462T2 (de) 1993-06-01 1994-04-26 Nicht-oxydierendes, medizinisches Polymerimplantat
DE69425838T Expired - Lifetime DE69425838T2 (de) 1993-06-01 1994-04-26 Nicht-oxydierendes, medizinisches Polymerimplantat
DE69413395T Expired - Lifetime DE69413395T2 (de) 1993-06-01 1994-04-26 Nicht oxydierendes, medizinisches polymerimplantat
DE9490446U Expired - Lifetime DE9490446U1 (de) 1993-06-01 1994-04-26 Nichtoxidierendes polymeres medizinisches Implantat

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE69434462T Expired - Lifetime DE69434462T2 (de) 1993-06-01 1994-04-26 Nicht-oxydierendes, medizinisches Polymerimplantat

Family Applications After (2)

Application Number Title Priority Date Filing Date
DE69413395T Expired - Lifetime DE69413395T2 (de) 1993-06-01 1994-04-26 Nicht oxydierendes, medizinisches polymerimplantat
DE9490446U Expired - Lifetime DE9490446U1 (de) 1993-06-01 1994-04-26 Nichtoxidierendes polymeres medizinisches Implantat

Country Status (9)

Country Link
US (10) US5414049A (de)
EP (4) EP1598086A2 (de)
JP (1) JP2836965B2 (de)
AT (3) ATE196095T1 (de)
AU (1) AU684500B2 (de)
CA (1) CA2162927C (de)
DE (4) DE69434462T2 (de)
ES (1) ES2122260T3 (de)
WO (1) WO1994027651A1 (de)

Families Citing this family (215)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5466530A (en) * 1993-01-21 1995-11-14 England; Garry L. Biocompatible components fabricated from a substantially consolidated stock of material
US5830396A (en) * 1993-01-21 1998-11-03 Biomet, Inc. Method for processing thermoplastics, thermosets and elastomers
US5414049A (en) * 1993-06-01 1995-05-09 Howmedica Inc. Non-oxidizing polymeric medical implant
US6596225B1 (en) 2000-01-31 2003-07-22 Diamicron, Inc. Methods for manufacturing a diamond prosthetic joint component
US6290726B1 (en) 2000-01-30 2001-09-18 Diamicron, Inc. Prosthetic hip joint having sintered polycrystalline diamond compact articulation surfaces
US6676704B1 (en) 1994-08-12 2004-01-13 Diamicron, Inc. Prosthetic joint component having at least one sintered polycrystalline diamond compact articulation surface and substrate surface topographical features in said polycrystalline diamond compact
US7494507B2 (en) * 2000-01-30 2009-02-24 Diamicron, Inc. Articulating diamond-surfaced spinal implants
US6517583B1 (en) 2000-01-30 2003-02-11 Diamicron, Inc. Prosthetic hip joint having a polycrystalline diamond compact articulation surface and a counter bearing surface
US6494918B1 (en) 2000-01-30 2002-12-17 Diamicron, Inc. Component for a prosthetic joint having a diamond load bearing and articulation surface
US6425922B1 (en) 2000-01-30 2002-07-30 Diamicron, Inc. Prosthetic hip joint having at least one sintered polycrystalline diamond compact articulation surface
US6800095B1 (en) 1994-08-12 2004-10-05 Diamicron, Inc. Diamond-surfaced femoral head for use in a prosthetic joint
US6514289B1 (en) 2000-01-30 2003-02-04 Diamicron, Inc. Diamond articulation surface for use in a prosthetic joint
US7678325B2 (en) * 1999-12-08 2010-03-16 Diamicron, Inc. Use of a metal and Sn as a solvent material for the bulk crystallization and sintering of diamond to produce biocompatbile biomedical devices
WO1996009330A1 (fr) * 1994-09-21 1996-03-28 Bmg Incorporated Piece moulee en polyethylene a poids moleculaire ultra eleve utile pour les articulations artificielles et son procede de fabrication
JP3380642B2 (ja) * 1995-01-18 2003-02-24 本田技研工業株式会社 車両の駆動力演算装置
CA2166450C (en) * 1995-01-20 2008-03-25 Ronald Salovey Chemically crosslinked ultrahigh molecular weight polyethylene for artificial human joints
US5577368A (en) * 1995-04-03 1996-11-26 Johnson & Johnson Professional, Inc. Method for improving wear resistance of polymeric bioimplantable components
US5674290A (en) * 1995-04-05 1997-10-07 Li; Shu-Tung Water-stabilized biopolymeric implants
RU2211008C2 (ru) * 1996-02-13 2003-08-27 Массачусетс Институт Оф Текнолоджи Протезные устройства из полиэтилена сверхвысокой молекулярной массы, обработанного облучением и плавлением
JP5073626B2 (ja) * 1996-02-13 2012-11-14 マサチューセッツ インスティテュート オブ テクノロジー 放射線および溶融処理済み超高分子量ポリエチレンプロテーゼデバイス
US20020156536A1 (en) * 1996-02-13 2002-10-24 Harris William H. Polyethylene hip joint prosthesis with extended range of motion
US5879400A (en) 1996-02-13 1999-03-09 Massachusetts Institute Of Technology Melt-irradiated ultra high molecular weight polyethylene prosthetic devices
US8865788B2 (en) * 1996-02-13 2014-10-21 The General Hospital Corporation Radiation and melt treated ultra high molecular weight polyethylene prosthetic devices
US8563623B2 (en) * 1996-02-13 2013-10-22 The General Hospital Corporation Radiation melt treated ultra high molecular weight polyethylene prosthetic devices
US5753182A (en) * 1996-02-14 1998-05-19 Biomet, Inc. Method for reducing the number of free radicals present in ultrahigh molecular weight polyethylene orthopedic components
US5598937A (en) * 1996-02-14 1997-02-04 Keystone Industries, Inc. Slackless drawbar assembly
US6228900B1 (en) 1996-07-09 2001-05-08 The Orthopaedic Hospital And University Of Southern California Crosslinking of polyethylene for low wear using radiation and thermal treatments
EP0935446B1 (de) * 1996-07-09 2007-02-07 Orthopaedic Hospital Vernetzung von polyethylen zur verringerung der abnutzung unter anwendung von strahlung und thermischer behandlung
US6017975A (en) 1996-10-02 2000-01-25 Saum; Kenneth Ashley Process for medical implant of cross-linked ultrahigh molecular weight polyethylene having improved balance of wear properties and oxidation resistance
AU4986497A (en) 1996-10-15 1998-05-11 Orthopaedic Hospital, The Wear resistant surface-gradient cross-linked polyethylene
IT1298376B1 (it) * 1997-12-16 2000-01-05 Samo Spa Trattamento di reticolazione e sterilizzazione per la produzione di manufatti in polietilene ad elevate caratteristiche tribologiche,
EP1413414B1 (de) * 1998-06-10 2006-12-13 Depuy Products, Inc. Verfahren zur Herstellung vernetzter geformter Kunststofflager
US6692679B1 (en) * 1998-06-10 2004-02-17 Depuy Orthopaedics, Inc. Cross-linked molded plastic bearings
JP4503114B2 (ja) * 1998-06-10 2010-07-14 デピュイ・オルソペディックス・インコーポレイテッド 架橋成形したプラスチック支持体
US5997969A (en) * 1998-08-27 1999-12-07 Gardon; John L. Non-allergenic medical and health care devices made from crosslinked synthetic elastomers
EP0995449A1 (de) * 1998-10-21 2000-04-26 Sulzer Orthopädie AG UHMW-Polyethylen für Implantate
EP0995450B1 (de) * 1998-10-21 2002-06-26 Sulzer Orthopädie AG UHMW-Polyethylen für Implantate
US6986868B2 (en) * 1998-11-20 2006-01-17 Coloplast A/S Method for sterilizing a medical device having a hydrophilic coating
AU754585B2 (en) * 1998-11-20 2002-11-21 Coloplast A/S A method for sterilising a medical device having a hydrophilic coating
AU3066400A (en) * 1999-01-22 2000-08-07 Multigig Limited Electronic circuitry
US6355215B1 (en) 1999-03-10 2002-03-12 Implex Corp. Wear-resistant olefinic medical implant and thermal treatment container therefor
US6203844B1 (en) 1999-04-01 2001-03-20 Joon B. Park Precoated polymeric prosthesis and process for making same
DE60028370T2 (de) 1999-04-21 2007-05-03 Howmedica Osteonics Corp. Verfahren zur herstellung einer selektiv vernetzten medizinischen prothese aus polyethylen, sowie eine dergestalt hergestellte prothese
US6239197B1 (en) * 1999-04-23 2001-05-29 Great Lakes Chemical Corporation Vacuum de-aerated powdered polymer additives
US6627141B2 (en) 1999-06-08 2003-09-30 Depuy Orthopaedics, Inc. Method for molding a cross-linked preform
US6245276B1 (en) 1999-06-08 2001-06-12 Depuy Orthopaedics, Inc. Method for molding a cross-linked preform
US6432349B1 (en) 1999-06-29 2002-08-13 Zimmer, Inc. Process of making an articulating bearing surface
EP1072274A1 (de) * 1999-07-29 2001-01-31 Depuy Orthopaedics, Inc. Zweistufige Gammabestrahlung von Polymer-Bioimplantaten
US6184265B1 (en) * 1999-07-29 2001-02-06 Depuy Orthopaedics, Inc. Low temperature pressure stabilization of implant component
US6143232A (en) * 1999-07-29 2000-11-07 Bristol-Meyers Squibb Company Method of manufacturing an articulating bearing surface for an orthopaedic implant
EP1072277A1 (de) * 1999-07-29 2001-01-31 Depuy Orthopaedics, Inc. Hitzebehandlung von gamma-bestrahlten Implantaten zur Erhöhung der mechanischen Stabilität
US6794423B1 (en) * 1999-07-30 2004-09-21 Stephen Li Fracture-resistant, cross-linked ultra high molecular weight polyethylene shaped material and articles made therefrom
US6365089B1 (en) 1999-09-24 2002-04-02 Zimmer, Inc. Method for crosslinking UHMWPE in an orthopaedic implant
US7569176B2 (en) * 1999-12-08 2009-08-04 Diamicron, Inc. Method for making a sintered superhard prosthetic joint component
US7556763B2 (en) * 1999-12-08 2009-07-07 Diamicron, Inc. Method of making components for prosthetic joints
US20100025898A1 (en) * 2000-01-30 2010-02-04 Pope Bill J USE OF Ti AND Nb CEMENTED TiC IN PROSTHETIC JOINTS
US20040199260A1 (en) * 2000-01-30 2004-10-07 Pope Bill J. Prosthetic joint component having at least one sintered polycrystalline diamond compact articulation surface and substrate surface topographical features in said polycrystalline diamond compact
US8603181B2 (en) * 2000-01-30 2013-12-10 Dimicron, Inc Use of Ti and Nb cemented in TiC in prosthetic joints
US20050203630A1 (en) * 2000-01-30 2005-09-15 Pope Bill J. Prosthetic knee joint having at least one diamond articulation surface
US6709463B1 (en) 2000-01-30 2004-03-23 Diamicron, Inc. Prosthetic joint component having at least one solid polycrystalline diamond component
US6410877B1 (en) 2000-01-30 2002-06-25 Diamicron, Inc. Methods for shaping and finishing prosthetic joint components including polycrystalline diamond compacts
US6395799B1 (en) 2000-02-21 2002-05-28 Smith & Nephew, Inc. Electromagnetic and mechanical wave energy treatments of UHMWPE
US6414086B1 (en) 2000-02-29 2002-07-02 Howmedica Osteonics Corp. Compositions, processes and methods of improving the wear resistance of prosthetic medical devices
US6626945B2 (en) 2000-03-14 2003-09-30 Chondrosite, Llc Cartilage repair plug
US6632246B1 (en) * 2000-03-14 2003-10-14 Chondrosite, Llc Cartilage repair plug
US8796347B2 (en) 2000-04-27 2014-08-05 Orthopaedic Hospital Oxidation-resistant and wear-resistant polyethylenes for human joint replacements and methods for making them
ES2286131T3 (es) * 2000-07-31 2007-12-01 Massachusetts General Hospital Componente acetabular monopolar constreñido.
US6579532B1 (en) * 2000-09-08 2003-06-17 Ferro Corporation Orthopedic mixtures prepared by supercritical fluid processing techniques
US6818172B2 (en) 2000-09-29 2004-11-16 Depuy Products, Inc. Oriented, cross-linked UHMWPE molding for orthopaedic applications
ATE336351T1 (de) * 2000-09-29 2006-09-15 Depuy Orthopaedics Inc Behandlung eines bestrahlten vorformlings eines prothetischen lagerelementes aus polyethylen mit einem überkritischen fluid
US6558426B1 (en) 2000-11-28 2003-05-06 Medidea, Llc Multiple-cam, posterior-stabilized knee prosthesis
DE10105085C1 (de) 2001-02-05 2002-04-18 Plus Endoprothetik Ag Rotkreuz Verfahren zur Herstellung von Implantatteilen aus hochvernetztem UHMWPE und deren Verwendung
JP3360073B2 (ja) * 2001-02-22 2002-12-24 花王株式会社 飲 料
US6547828B2 (en) 2001-02-23 2003-04-15 Smith & Nephew, Inc. Cross-linked ultra-high molecular weight polyethylene for medical implant use
JP3757264B2 (ja) * 2001-03-27 2006-03-22 独立行政法人産業技術総合研究所 シルセスキオキサン系ポリマー成形体及びその製造方法
US20030019106A1 (en) * 2001-04-22 2003-01-30 Diamicron, Inc. Methods for making bearings, races and components thereof having diamond and other superhard surfaces
US6655845B1 (en) * 2001-04-22 2003-12-02 Diamicron, Inc. Bearings, races and components thereof having diamond and other superhard surfaces
US7695521B2 (en) 2001-05-01 2010-04-13 Amedica Corporation Hip prosthesis with monoblock ceramic acetabular cup
US7776085B2 (en) 2001-05-01 2010-08-17 Amedica Corporation Knee prosthesis with ceramic tibial component
EP1389978B1 (de) * 2001-05-01 2009-01-07 Amedica Corporation Röntgendurchlässiges knochentransplantat
EP1408874B1 (de) 2001-06-14 2012-08-08 Amedica Corporation Metall-keramik-verbundgelenk
US7182784B2 (en) * 2001-07-18 2007-02-27 Smith & Nephew, Inc. Prosthetic devices employing oxidized zirconium and other abrasion resistant surfaces contacting surfaces of cross-linked polyethylene
US6652586B2 (en) * 2001-07-18 2003-11-25 Smith & Nephew, Inc. Prosthetic devices employing oxidized zirconium and other abrasion resistant surfaces contacting surfaces of cross-linked polyethylene
GB0122117D0 (en) * 2001-09-13 2001-10-31 United Ind Operations Ltd Method of crosslinking polyolefins
DE10149884B4 (de) * 2001-10-10 2005-02-17 Hubert Rosing Verfahren zur Herstellung von Halbzeugen aus hoch- oder ultrahochmolekularen Polymeren, derart hergestellte Halbzeuge sowie deren Verwendung
US7150853B2 (en) * 2001-11-01 2006-12-19 Advanced Cardiovascular Systems, Inc. Method of sterilizing a medical device
DE10160329A1 (de) * 2001-12-07 2003-06-18 Merck Patent Gmbh Polymerbasierter Werkstoff enthaltend Silicapartikel
US7160492B2 (en) * 2001-12-12 2007-01-09 Depuy Products, Inc. Orthopaedic device for implantation in the body of an animal and method for making the same
EP1463457A4 (de) * 2002-01-04 2006-12-20 Massachusetts Gen Hospital Vernetztes polyethylen mit hohem spannungswert, mit reduzierter restradikalkonzentration; hergestellt unter dem schmelzpunkt
US7186364B2 (en) 2002-01-28 2007-03-06 Depuy Products, Inc. Composite prosthetic bearing constructed of polyethylene and an ethylene-acrylate copolymer and method for making the same
US7819925B2 (en) * 2002-01-28 2010-10-26 Depuy Products, Inc. Composite prosthetic bearing having a crosslinked articulating surface and method for making the same
EP1332733B1 (de) 2002-01-28 2006-06-14 Depuy Products, Inc. Prothesenverbundlager und Herstellungsverfahren
EP1448360B1 (de) * 2002-01-29 2005-12-14 Paul Smith Sintern von ultrahochmolekularem polyethylen
EP1369094B1 (de) 2002-05-31 2014-11-26 Zimmer GmbH Implantat und Verfahren zur Herstellung eines steril verpackten Implantats
CA2429930C (en) * 2002-06-06 2008-10-14 Howmedica Osteonics Corp. Sequentially cross-linked polyethylene
US20040002770A1 (en) * 2002-06-28 2004-01-01 King Richard S. Polymer-bioceramic composite for orthopaedic applications and method of manufacture thereof
ES2294350T3 (es) * 2002-12-10 2008-04-01 Dsm Ip Assets B.V. Proceso de fabricacion y proceso de conversion de fibras poliolefinicas.
AU2003297195A1 (en) 2002-12-17 2004-07-22 Amedica Corporation Total disc implant
EP2664299A1 (de) * 2003-01-16 2013-11-20 Massachusetts General Hospital Verfahren zur Herstellung von oxidationsbeständigem Polymermaterial
US7938861B2 (en) * 2003-04-15 2011-05-10 Depuy Products, Inc. Implantable orthopaedic device and method for making the same
EP1624906A1 (de) * 2003-05-19 2006-02-15 Tjaart Andries Du Plessis Darstellung eines osteoinduktiven mittels
US20060243624A1 (en) * 2003-06-10 2006-11-02 Meadwestvaco Corporation Resin packaging
US7214764B2 (en) * 2003-06-30 2007-05-08 Depuy Products, Inc. Free radical quench process for irradiated ultrahigh molecular weight polyethylene
US20040265165A1 (en) * 2003-06-30 2004-12-30 Depuy Products, Inc. Free radical quench process for irradiated ultrahigh molecular weight polyethylene
US20040262809A1 (en) * 2003-06-30 2004-12-30 Smith Todd S. Crosslinked polymeric composite for orthopaedic implants
US20050133277A1 (en) * 2003-08-28 2005-06-23 Diamicron, Inc. Superhard mill cutters and related methods
US20050065307A1 (en) * 2003-09-19 2005-03-24 Depuy Products, Inc. Medical implant or medical implant part comprising porous UHMWPE and process for producing the same
US6996952B2 (en) * 2003-09-30 2006-02-14 Codman & Shurtleff, Inc. Method for improving stability and effectivity of a drug-device combination product
US7205051B2 (en) * 2003-09-30 2007-04-17 Depuy Products, Inc. Medical implant or medical implant part
GB2429164B (en) * 2004-03-11 2008-12-24 Acumed Llc Systems for bone replacement
US7833452B2 (en) 2004-05-11 2010-11-16 The General Hospital Corporation Method for making oxidation resistant polymeric material
US7384430B2 (en) * 2004-06-30 2008-06-10 Depuy Products, Inc. Low crystalline polymeric material for orthopaedic implants and an associated method
US7462318B2 (en) * 2004-10-07 2008-12-09 Biomet Manufacturing Corp. Crosslinked polymeric material with enhanced strength and process for manufacturing
US8262976B2 (en) 2004-10-07 2012-09-11 Biomet Manufacturing Corp. Solid state deformation processing of crosslinked high molecular weight polymeric materials
US7344672B2 (en) * 2004-10-07 2008-03-18 Biomet Manufacturing Corp. Solid state deformation processing of crosslinked high molecular weight polymeric materials
US7547405B2 (en) 2004-10-07 2009-06-16 Biomet Manufacturing Corp. Solid state deformation processing of crosslinked high molecular weight polymeric materials
US20060142868A1 (en) * 2004-12-21 2006-06-29 Zimmer Technology, Inc. Selective crosslinking of orthopaedic implants
US7335697B2 (en) * 2004-12-23 2008-02-26 Depuy Products, Inc. Polymer composition comprising cross-linked polyethylene and methods for making the same
US7896921B2 (en) * 2004-12-30 2011-03-01 Depuy Products, Inc. Orthopaedic bearing and method for making the same
US7879275B2 (en) * 2004-12-30 2011-02-01 Depuy Products, Inc. Orthopaedic bearing and method for making the same
US7883653B2 (en) 2004-12-30 2011-02-08 Depuy Products, Inc. Method of making an implantable orthopaedic bearing
US7435372B2 (en) * 2005-03-31 2008-10-14 Zimmer, Inc. Liquid bath annealing of polymers for orthopaedic implants
US8449991B2 (en) 2005-04-07 2013-05-28 Dimicron, Inc. Use of SN and pore size control to improve biocompatibility in polycrystalline diamond compacts
CN101166531A (zh) * 2005-04-20 2008-04-23 日绊株式会社 经皮吸收制剂
WO2006130869A1 (en) * 2005-06-02 2006-12-07 Alza Corporation Method for terminal sterilization of transdermal delivery devices
US20060280644A1 (en) * 2005-06-02 2006-12-14 Scott Sellers Method for terminal sterilization of transdermal delivery devices
EP1890864B1 (de) * 2005-06-14 2015-12-30 OMNIlife science, Inc. Vernetzter polyethylenartikel
US7538379B1 (en) * 2005-06-15 2009-05-26 Actel Corporation Non-volatile two-transistor programmable logic cell and array layout
ES2441608T3 (es) 2005-08-18 2014-02-05 Zimmer Gmbh Artículos de polietileno de peso molecular ultra-alto y métodos para formar artículos de polietileno de peso molecular ulra-alto
JP2009504899A (ja) * 2005-08-22 2009-02-05 ザ ジェネラル ホスピタル コーポレイション ディー ビー エイ マサチューセッツ ジェネラル ホスピタル 耐酸化性の均質化した重合体状材料
US8343230B2 (en) * 2005-09-22 2013-01-01 Depuy Products, Inc. Orthopaedic bearing material
US20070077268A1 (en) * 2005-09-30 2007-04-05 Depuy Products, Inc. Hydrophobic carrier modified implants for beneficial agent delivery
US8252058B2 (en) 2006-02-16 2012-08-28 Amedica Corporation Spinal implant with elliptical articulatory interface
US20070209957A1 (en) * 2006-03-09 2007-09-13 Sdgi Holdings, Inc. Packaging system for medical devices
US7812098B2 (en) * 2006-03-31 2010-10-12 Depuy Products, Inc. Bearing material of medical implant having reduced wear rate and method for reducing wear rate
US20070232716A1 (en) * 2006-04-04 2007-10-04 Fina Technology, Inc. Cross-linking resins
US20080036111A1 (en) * 2006-08-09 2008-02-14 Dehchuan Sun Non-oxidizing thermally crosslinked polymeric material and medical implant
DE602007009345D1 (de) 2006-08-25 2010-11-04 Depuy Products Inc Material zum Tragen eines medizinischen Implantats
WO2008025851A1 (de) * 2006-09-01 2008-03-06 Basf Se Rückgewinnung von phenol-liganden bei der herstellung von isopulegol
EP2460636A1 (de) * 2006-10-30 2012-06-06 Smith & Nephew Orthopaedics AG Verfahren mit Vernetzung von Polyethylen oder Verwendung von vernetztem Polyethylen
JP5448842B2 (ja) 2007-01-10 2014-03-19 バイオメト マニファクチャリング コーポレイション 膝関節プロテーゼシステムおよび埋込み方法
US8328873B2 (en) 2007-01-10 2012-12-11 Biomet Manufacturing Corp. Knee joint prosthesis system and method for implantation
US8187280B2 (en) 2007-10-10 2012-05-29 Biomet Manufacturing Corp. Knee joint prosthesis system and method for implantation
US8163028B2 (en) 2007-01-10 2012-04-24 Biomet Manufacturing Corp. Knee joint prosthesis system and method for implantation
US8562616B2 (en) 2007-10-10 2013-10-22 Biomet Manufacturing, Llc Knee joint prosthesis system and method for implantation
EP2110002B1 (de) 2007-01-25 2012-04-25 The General Hospital Corporation Verfahren zur herstellung von oxidationsbeständigem vernetztem polymermaterial
WO2008101073A2 (en) * 2007-02-14 2008-08-21 Brigham And Women's Hospital, Inc. Crosslinked polymers
WO2008113388A1 (en) * 2007-03-20 2008-09-25 Plus Orthopedics Ag Oxidation resistant highly-crosslinked uhmwpe
PL2126167T3 (pl) * 2007-03-27 2011-02-28 Dsm Ip Assets Bv Sposób usuwania resztkowego rozpuszczalnika przędzalniczego z włókna przędzonego z żelu, włókno, przędza wielowłóknowa oraz produkty zawierające włókno
US8664290B2 (en) 2007-04-10 2014-03-04 Zimmer, Inc. Antioxidant stabilized crosslinked ultra-high molecular weight polyethylene for medical device applications
ATE544476T1 (de) 2007-04-10 2012-02-15 Zimmer Inc Antioxidans-stabilisiertes vernetztes ultrahochmolekulares polyethylen für anwendungen in medizinprodukten
US8641959B2 (en) * 2007-07-27 2014-02-04 Biomet Manufacturing, Llc Antioxidant doping of crosslinked polymers to form non-eluting bearing components
CN101998974B (zh) * 2007-09-04 2014-10-29 史密夫和内修整形外科股份公司 用于支撑表面的超高分子量聚乙烯
US8128703B2 (en) * 2007-09-28 2012-03-06 Depuy Products, Inc. Fixed-bearing knee prosthesis having interchangeable components
US20110035018A1 (en) * 2007-09-25 2011-02-10 Depuy Products, Inc. Prosthesis with composite component
US8632600B2 (en) 2007-09-25 2014-01-21 Depuy (Ireland) Prosthesis with modular extensions
US20110035017A1 (en) * 2007-09-25 2011-02-10 Depuy Products, Inc. Prosthesis with cut-off pegs and surgical method
US8715359B2 (en) 2009-10-30 2014-05-06 Depuy (Ireland) Prosthesis for cemented fixation and method for making the prosthesis
US9204967B2 (en) 2007-09-28 2015-12-08 Depuy (Ireland) Fixed-bearing knee prosthesis having interchangeable components
EP2209726A4 (de) * 2007-10-12 2012-08-15 Peak Plastic & Metal Prod Plättchenbehälter mit versetzter wandstruktur
JP5682914B2 (ja) * 2007-11-06 2015-03-11 ディーエスエム アイピー アセッツ ビー．ブイ． 高分子量ポリエチレンの生産方法
AU2009209158B2 (en) 2008-01-30 2013-09-19 Zimmer, Inc. Orthopedic component of low stiffness
ES2439586T3 (es) * 2008-05-13 2014-01-23 Smith & Nephew Orthopaedics Ag UHMWPE altamente reticulado resistente a la oxidación
US20090288366A1 (en) 2008-05-23 2009-11-26 Phillip Andrew Schorr Vacuum packaged products and methods for making same
US9095324B2 (en) * 2008-06-20 2015-08-04 Boston Scientific Scimed, Inc. Package assembly
US8187335B2 (en) 2008-06-30 2012-05-29 Depuy Products, Inc. Posterior stabilized orthopaedic knee prosthesis having controlled condylar curvature
US9119723B2 (en) 2008-06-30 2015-09-01 Depuy (Ireland) Posterior stabilized orthopaedic prosthesis assembly
US8828086B2 (en) 2008-06-30 2014-09-09 Depuy (Ireland) Orthopaedic femoral component having controlled condylar curvature
US8192498B2 (en) * 2008-06-30 2012-06-05 Depuy Products, Inc. Posterior cructiate-retaining orthopaedic knee prosthesis having controlled condylar curvature
US8236061B2 (en) 2008-06-30 2012-08-07 Depuy Products, Inc. Orthopaedic knee prosthesis having controlled condylar curvature
US9168145B2 (en) 2008-06-30 2015-10-27 Depuy (Ireland) Posterior stabilized orthopaedic knee prosthesis having controlled condylar curvature
US8206451B2 (en) 2008-06-30 2012-06-26 Depuy Products, Inc. Posterior stabilized orthopaedic prosthesis
US20100022677A1 (en) * 2008-07-24 2010-01-28 Zimmer, Inc. Reduction of free radicals in crosslinked polyethylene by infrared heating
US20100022678A1 (en) * 2008-07-24 2010-01-28 Zimmer, Inc. Reduction of free radicals in crosslinked polyethylene by infrared heating
US8133436B2 (en) * 2008-08-05 2012-03-13 Howmedica Osteonics Corp. Polyethylene cross-linked with an anthocyanin
US8765040B2 (en) * 2008-08-11 2014-07-01 Abbott Cardiovascular Systems Inc. Medical device fabrication process including strain induced crystallization with enhanced crystallization
DE102008053793A1 (de) 2008-10-21 2010-04-22 Aesculap Ag Antioxidativ wirksames, synthetisches Polymermaterial
CN102307945B (zh) 2008-11-20 2015-07-01 捷迈有限责任公司 聚乙烯材料
US9101476B2 (en) 2009-05-21 2015-08-11 Depuy (Ireland) Prosthesis with surfaces having different textures and method of making the prosthesis
US11213397B2 (en) 2009-05-21 2022-01-04 Depuy Ireland Unlimited Company Prosthesis with surfaces having different textures and method of making the prosthesis
US8663359B2 (en) * 2009-06-26 2014-03-04 Dimicron, Inc. Thick sintered polycrystalline diamond and sintered jewelry
EP2316384B1 (de) 2009-10-30 2013-04-03 DePuy Products, Inc. Prothese mit modularen Erweiterungen
EP2319460A1 (de) 2009-10-30 2011-05-11 DePuy Products, Inc. Prothese mit stumpfen Zapfen
EP2606857A1 (de) 2009-10-30 2013-06-26 DePuy Products, Inc. Prothese mit Verbundstoffkomponente
EP2316382B1 (de) 2009-10-30 2014-03-05 DePuy (Ireland) Prothese für zementfreie Verankerung
ES2532826T3 (es) 2009-10-30 2015-04-01 DePuy Synthes Products, LLC Prótesis con superficies de texturas diferentes
US9011547B2 (en) 2010-01-21 2015-04-21 Depuy (Ireland) Knee prosthesis system
MY174484A (en) 2010-01-22 2020-04-22 Allegiance Corp Methods for packaging and sterilizing elastomeric articles, and packaged elastomeric articles produced thereby
US8613880B2 (en) 2010-04-21 2013-12-24 Abbott Cardiovascular Systems Inc. Post electron beam conditioning of polymeric medical devices
US8715569B2 (en) * 2010-08-20 2014-05-06 Abbott Cardiovascular Systems Inc. Post electron beam stabilization of polymeric medical devices
US9132209B2 (en) 2010-05-07 2015-09-15 Howmedia Osteonics Corp. Surface crosslinked polyethylene
US8399535B2 (en) 2010-06-10 2013-03-19 Zimmer, Inc. Polymer [[s]] compositions including an antioxidant
US8235209B2 (en) 2010-08-11 2012-08-07 Boston Scientific Scimed, Inc. Medical device packaging and methods for preparing and packaging medical devices
US9096368B2 (en) 2011-01-19 2015-08-04 Boston Scientific Scimed, Inc. Medical device packaging and methods for preparing and packaging medical devices
US8973748B2 (en) 2011-01-19 2015-03-10 Boston Scientific Scime, Inc. Medical device packaging and methods for preparing and packaging medical devices
US8966868B2 (en) * 2011-05-09 2015-03-03 Abbott Cardiovascular Systems Inc. Methods of stabilizing molecular weight of polymer stents after sterilization
US8556970B2 (en) * 2011-09-28 2013-10-15 Depuy Mitek, Llc Graft introducer
WO2013057724A1 (en) * 2011-10-21 2013-04-25 Ranbaxy Laboratories Limited Packaging for alitretinoin
DE102012010155B4 (de) 2012-05-24 2015-06-11 Pan-Biotech Gmbh Zellkulturbehälter für den Einmalgebrauch
GB2507640B (en) 2012-09-10 2015-08-26 Acumed Llc Radial head prosthesis with floating articular member
BR112015022171B1 (pt) 2013-03-14 2023-01-03 Fresenius Kabi Deutschland Gmbh Sistema de embalagem farmacêutica para um fármaco sensível ao oxigênio injetável
US9072781B2 (en) 2013-03-14 2015-07-07 Becton, Dickinson France S.A.S. Morphine formulations
US9237953B2 (en) 2013-03-15 2016-01-19 Depuy (Ireland) Mechanical assembly of pegs to prosthesis
US20160279055A1 (en) 2013-07-22 2016-09-29 Imprimis Pharmaceuticals, Inc. Pharmaceutical ophthalmic compositions for intraocular administration and methods for fabricating thereof
US9586370B2 (en) 2013-08-15 2017-03-07 Biomet Manufacturing, Llc Method for making ultra high molecular weight polyethylene
WO2015050851A1 (en) 2013-10-01 2015-04-09 Zimmer, Inc. Polymer compositions comprising one or more protected antioxidants
US9144499B2 (en) 2013-12-17 2015-09-29 Depuy (Ireland) Low profile mobile/fixed prosthetic knee systems
WO2015138137A1 (en) 2014-03-12 2015-09-17 Zimmer, Inc. Melt-stabilized ultra high molecular weight polyethylene and method of making the same
US20150266210A1 (en) 2014-03-21 2015-09-24 Howmedica Osteonics Corp. Annealing method for cross-linked polyethylene
WO2016090084A1 (en) 2014-12-03 2016-06-09 Zimmer, Inc. Antioxidant-infused ultra high molecular weight polyethylene
US9763792B2 (en) 2015-10-01 2017-09-19 Acumed Llc Radial head prosthesis with rotate-to-lock interface
US10070959B2 (en) 2016-09-28 2018-09-11 DePuy Synthes Products, Inc. Method of texturing prosthetic implants
EP4097153A1 (de) 2020-01-27 2022-12-07 Formosa Plastics Corporation, U.S.A. Verfahren zum herstellen von katalysatoren und katalysatorzusammensetzungen
US11952439B2 (en) 2020-06-25 2024-04-09 b-ONE Medical (Suzhou) Co., Ltd. Surface gradient cross-linking method of ultra-high molecular weight polyethylene and the application thereof
WO2023239560A1 (en) 2022-06-09 2023-12-14 Formosa Plastics Corporaton, U.S.A. Clay composite support-activators and catalyst compositions

Family Cites Families (70)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE544324A (de) 1955-01-11
US2904480A (en) 1955-06-06 1959-09-15 Grace W R & Co Polyethylene
US3563869A (en) * 1957-11-05 1971-02-16 Grace W R & Co Irradiated polyethylene
US3022543A (en) 1958-02-07 1962-02-27 Grace W R & Co Method of producing film having improved shrink energy
US3057791A (en) 1959-07-06 1962-10-09 Phillips Petroleum Co Radiation curing of polymers
US3090770A (en) 1960-04-26 1963-05-21 Grace W R & Co Blended polyethylene compositions of improved clarity and method of making same
US3162623A (en) 1961-12-26 1964-12-22 Du Pont Crosslinking of polymers with nitrogen fluorides
US3362897A (en) * 1962-11-21 1968-01-09 Gen Electric Stable irradiated polyethylene
US3297641A (en) * 1964-01-17 1967-01-10 Grace W R & Co Process for cross-linking polyethylene
DE1241994B (de) * 1964-01-31 1967-06-08 Glanzstoff Ag Verfahren zur Absaettigung von Doppelbindungen in Polyolefinen
DE1669649B2 (de) 1966-05-27 1971-05-19 Badische Anilin- & Soda-Fabrik Ag, 6700 Ludwigshafen Verfahren zum herstellen feinteiliger schaumfoermiger olefin polymerisate mit hoher waermestandfestigkeit
US3832827A (en) * 1967-12-18 1974-09-03 J Lemelson Container forming and filling apparatus
US3758273A (en) * 1970-04-03 1973-09-11 Gillette Co Processes for sterilizing polypropylene objects
GB1324919A (en) * 1970-11-13 1973-07-25 Atomic Energy Commission Preparation of filled polyethylenes
JPS526314B2 (de) 1971-11-01 1977-02-21
AU523866B2 (en) 1978-04-18 1982-08-19 Du Pont Canada Inc. Manufacture of film
US4241463A (en) 1978-10-16 1980-12-30 Precision Cast Specialties, Inc. Prosthetic implant device
DE3069144D1 (en) * 1979-06-06 1984-10-18 Nat Res Dev Polymer processing
US5017627A (en) 1980-10-09 1991-05-21 National Research Development Corporation Composite material for use in orthopaedics
US4586995A (en) * 1982-09-17 1986-05-06 Phillips Petroleum Company Polymer and irradiation treatment method
JPS5971830A (ja) 1982-10-18 1984-04-23 Nippon Sheet Glass Co Ltd 屈折率分布型レンズ体の製造方法
GB8332952D0 (en) * 1983-12-09 1984-01-18 Ward I M Polymer irradiation
US4587163A (en) * 1984-03-06 1986-05-06 Zachariades Anagnostis E Preparation of ultra high molecular weight polyethylene morphologies of totally fused particles with superior mechanical performance
GB2156733B (en) * 1984-03-30 1987-10-28 Nat Res Dev Die drawing of tubular thermoplastics
EP0161802B1 (de) * 1984-04-13 1990-06-27 National Research Development Corporation Verfahren zum Verformen im festen Zustand
US4655769A (en) * 1984-10-24 1987-04-07 Zachariades Anagnostis E Ultra-high-molecular-weight polyethylene products including vascular prosthesis devices and methods relating thereto and employing pseudo-gel states
US4820466A (en) * 1985-01-31 1989-04-11 Zachariades Anagnostis E Process for obtaining ultra-high modulus products
US4950151A (en) * 1985-01-31 1990-08-21 Zachariades Anagnostic E Rolling die for producing high modulus products
ZA86528B (en) 1985-01-31 1986-09-24 Himont Inc Polypropylene with free-end long chain branching,process for making it,and use thereof
DE3545116A1 (de) 1985-05-17 1986-11-20 Transaktor KB International, Göteborg Flasche fuer wassernotverpflegung und verfahren zur herstellung einer flasche mit wassernotverpflegung
US4701288A (en) * 1985-06-05 1987-10-20 Bausch & Lomb Incorporated Method of making articles of dissimilar polymer compositions
JPS6274364A (ja) * 1985-09-27 1987-04-06 株式会社　ニツシヨ− 医療用具
US4965846A (en) * 1986-08-11 1990-10-23 Baxter International Inc. Pivot pin bearing/seal with loose eyelet especially suited for disposable continuous flow blood filtration system cartridges
GB2207436B (en) * 1987-07-24 1991-07-24 Nat Research And Dev Corp The Solid phase deformation process
US5047446A (en) 1988-07-22 1991-09-10 Himont Incorporated Thermal treatment of irradiated propylene polymer material
GB8827967D0 (en) * 1988-11-30 1989-01-05 Ward I M Die-free drawing
ATE122901T1 (de) * 1988-12-02 1995-06-15 Du Pont Verfahren zur herstellung von gegenständen aus polyethylen mit ultrahohem molekulargewicht.
DE68926624T2 (de) * 1988-12-02 1996-10-02 Du Pont Lineares polyäthylen von ultrahohem molekulargewicht, gegenstände und verfahren zu deren herstellung
US5030402A (en) * 1989-03-17 1991-07-09 Zachariades Anagnostis E Process for producing a new class of ultra-high-molecular-weight polyethylene orthopaedic prostheses with enhanced mechanical properties
US5037928A (en) * 1989-10-24 1991-08-06 E. I. Du Pont De Nemours And Company Process of manufacturing ultrahigh molecular weight linear polyethylene shaped articles
US5160677A (en) * 1989-12-15 1992-11-03 United States Surgical Corporation Pressurized powder support for treating processes
CA2031406C (en) 1989-12-21 2002-05-28 Paolo Galli Graft copolymers of polyolefins and a method of producing same
US5153039A (en) * 1990-03-20 1992-10-06 Paxon Polymer Company, L.P. High density polyethylene article with oxygen barrier properties
US5200439A (en) * 1990-04-13 1993-04-06 Mitsui Toatsu Chemicals, Inc. Method for increasing intrinsic viscosity of syndiotactic polypropylene
NL9001745A (nl) * 1990-08-01 1992-03-02 Stamicarbon Oplossing van ultra-hoog moleculair polyetheen.
US5352732A (en) * 1990-08-07 1994-10-04 E. I. Du Pont De Nemours And Company Homogeneous, high modulus ultrahigh molecular weight polyethylene composites and processes for the preparation thereof
US5292584A (en) 1991-04-11 1994-03-08 E. I. Du Pont De Nemours And Company Ultrahigh molecular weight polyethylene and lightly-filled composites thereof
US5508319A (en) * 1991-06-21 1996-04-16 Montell North America Inc. High melt strength, ethylene polymer, process for making it, and use thereof
US5466530A (en) * 1993-01-21 1995-11-14 England; Garry L. Biocompatible components fabricated from a substantially consolidated stock of material
US5414049A (en) * 1993-06-01 1995-05-09 Howmedica Inc. Non-oxidizing polymeric medical implant
AU7634094A (en) 1993-08-20 1995-03-21 Smith & Nephew Richards Inc. Self-reinforced ultra-high molecular weight polyethylene composites
WO1996009330A1 (fr) * 1994-09-21 1996-03-28 Bmg Incorporated Piece moulee en polyethylene a poids moleculaire ultra eleve utile pour les articulations artificielles et son procede de fabrication
CA2166450C (en) * 1995-01-20 2008-03-25 Ronald Salovey Chemically crosslinked ultrahigh molecular weight polyethylene for artificial human joints
US5609643A (en) 1995-03-13 1997-03-11 Johnson & Johnson Professional, Inc. Knee joint prosthesis
US5577368A (en) 1995-04-03 1996-11-26 Johnson & Johnson Professional, Inc. Method for improving wear resistance of polymeric bioimplantable components
US5879400A (en) * 1996-02-13 1999-03-09 Massachusetts Institute Of Technology Melt-irradiated ultra high molecular weight polyethylene prosthetic devices
RU2211008C2 (ru) * 1996-02-13 2003-08-27 Массачусетс Институт Оф Текнолоджи Протезные устройства из полиэтилена сверхвысокой молекулярной массы, обработанного облучением и плавлением
US5753182A (en) * 1996-02-14 1998-05-19 Biomet, Inc. Method for reducing the number of free radicals present in ultrahigh molecular weight polyethylene orthopedic components
US6228900B1 (en) * 1996-07-09 2001-05-08 The Orthopaedic Hospital And University Of Southern California Crosslinking of polyethylene for low wear using radiation and thermal treatments
US6017975A (en) * 1996-10-02 2000-01-25 Saum; Kenneth Ashley Process for medical implant of cross-linked ultrahigh molecular weight polyethylene having improved balance of wear properties and oxidation resistance
AU4986497A (en) * 1996-10-15 1998-05-11 Orthopaedic Hospital, The Wear resistant surface-gradient cross-linked polyethylene
US5874123A (en) * 1997-01-24 1999-02-23 Park; Joon B. Precoated polymeric prosthesis and process for making same
US6432349B1 (en) * 1999-06-29 2002-08-13 Zimmer, Inc. Process of making an articulating bearing surface
US6184265B1 (en) * 1999-07-29 2001-02-06 Depuy Orthopaedics, Inc. Low temperature pressure stabilization of implant component
US6143232A (en) * 1999-07-29 2000-11-07 Bristol-Meyers Squibb Company Method of manufacturing an articulating bearing surface for an orthopaedic implant
JP4400970B2 (ja) * 1999-11-22 2010-01-20 若井産業株式会社 ナットの包装方法と包装体
WO2001052110A2 (en) * 2000-01-13 2001-07-19 Orbidex, Inc. System and method of searching and gathering information on-line and off-line
US6395799B1 (en) * 2000-02-21 2002-05-28 Smith & Nephew, Inc. Electromagnetic and mechanical wave energy treatments of UHMWPE
US6503439B1 (en) * 2000-06-15 2003-01-07 Albert H. Burstein Process for forming shaped articles of ultra high molecular weight polyethylene suitable for use as a prosthetic device or a component thereof
US6547828B2 (en) * 2001-02-23 2003-04-15 Smith & Nephew, Inc. Cross-linked ultra-high molecular weight polyethylene for medical implant use

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EP0847765A1 (de) 1998-06-17
DE69425838D1 (de) 2000-10-12
DE69413395D1 (de) 1998-10-22
AU684500B2 (en) 1997-12-18
ATE171078T1 (de) 1998-10-15
US20030207957A1 (en) 2003-11-06
US5650485A (en) 1997-07-22
DE69434462T2 (de) 2006-06-08
US6372814B1 (en) 2002-04-16
US6818020B2 (en) 2004-11-16
US20020107299A1 (en) 2002-08-08
DE69413395T2 (de) 1999-02-04
EP0701453A1 (de) 1996-03-20
AU6436494A (en) 1994-12-20
US5543471A (en) 1996-08-06
US20050059750A1 (en) 2005-03-17
ES2122260T3 (es) 1998-12-16
US5449745A (en) 1995-09-12
US5414049A (en) 1995-05-09
JP2836965B2 (ja) 1998-12-14
US5728748A (en) 1998-03-17
EP0701453B1 (de) 1998-09-16
EP1005872B1 (de) 2005-08-17
ATE196095T1 (de) 2000-09-15
ATE302032T1 (de) 2005-09-15
DE69434462D1 (de) 2005-09-22
CA2162927C (en) 2000-07-04
US6174934B1 (en) 2001-01-16
EP1598086A2 (de) 2005-11-23
WO1994027651A1 (en) 1994-12-08
DE9490446U1 (de) 1997-02-20
US6664308B2 (en) 2003-12-16
EP1005872A1 (de) 2000-06-07
JPH08509148A (ja) 1996-10-01
EP0847765B1 (de) 2000-09-06

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