DE69427115T2 - Verfahren zur messung der antithrombin-iii-aktivität - Google Patents

Verfahren zur messung der antithrombin-iii-aktivität

Info

Publication number
DE69427115T2
DE69427115T2 DE69427115T DE69427115T DE69427115T2 DE 69427115 T2 DE69427115 T2 DE 69427115T2 DE 69427115 T DE69427115 T DE 69427115T DE 69427115 T DE69427115 T DE 69427115T DE 69427115 T2 DE69427115 T2 DE 69427115T2
Authority
DE
Germany
Prior art keywords
antithrombin iii
iii activity
measuring antithrombin
measuring
activity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69427115T
Other languages
English (en)
Other versions
DE69427115D1 (de
Inventor
Masayasu Enomoto
Haruhiko Nishimura
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Azwell Inc
Original Assignee
Azwell Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Azwell Inc filed Critical Azwell Inc
Publication of DE69427115D1 publication Critical patent/DE69427115D1/de
Application granted granted Critical
Publication of DE69427115T2 publication Critical patent/DE69427115T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/56—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving blood clotting factors, e.g. involving thrombin, thromboplastin, fibrinogen
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2337/00—N-linked chromogens for determinations of peptidases and proteinases
    • C12Q2337/10—Anilides
    • C12Q2337/12—Para-Nitroanilides p-NA
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/81—Protease inhibitors
    • G01N2333/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • G01N2333/811—Serine protease (E.C. 3.4.21) inhibitors
    • G01N2333/8121—Serpins
    • G01N2333/8128—Antithrombin III
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
    • G01N2333/974—Thrombin
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2400/00—Assays, e.g. immunoassays or enzyme assays, involving carbohydrates
    • G01N2400/10—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • G01N2400/38—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence, e.g. gluco- or galactomannans, e.g. Konjac gum, Locust bean gum, Guar gum
    • G01N2400/40—Glycosaminoglycans, i.e. GAG or mucopolysaccharides, e.g. chondroitin sulfate, dermatan sulfate, hyaluronic acid, heparin, heparan sulfate, and related sulfated polysaccharides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/81—Packaged device or kit
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/975—Kit
DE69427115T 1993-06-28 1994-06-27 Verfahren zur messung der antithrombin-iii-aktivität Expired - Fee Related DE69427115T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP5157001A JPH078298A (ja) 1993-06-28 1993-06-28 アンチトロンビンｉｉｉ活性の測定方法および該測定用試薬キット
PCT/JP1994/001024 WO1995000663A1 (fr) 1993-06-28 1994-06-27 Methode de titrage de l'activite de l'antithrombine iii et kit de reactifs conçu a cet effet

Publications (2)

Publication Number Publication Date
DE69427115D1 DE69427115D1 (de) 2001-05-23
DE69427115T2 true DE69427115T2 (de) 2001-08-30

Family

ID=15640022

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69427115T Expired - Fee Related DE69427115T2 (de) 1993-06-28 1994-06-27 Verfahren zur messung der antithrombin-iii-aktivität

Country Status (5)

Country Link
US (1) US5646007A (de)
EP (1) EP0657547B1 (de)
JP (1) JPH078298A (de)
DE (1) DE69427115T2 (de)
WO (1) WO1995000663A1 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE200580T1 (de) * 1996-08-17 2001-04-15 Aventis Behring Gmbh Verfahren zur quantifizierung von glykosaminoglykanen in antithrombin iii-haltigen lösungen
AU744025B2 (en) * 1997-12-09 2002-02-14 Sigma-Aldrich Co. Plasma reference
US5985582A (en) * 1997-12-09 1999-11-16 Sigma-Aldrich Co. Thrombin-based assay for antithrombin III
DE10239821A1 (de) * 2002-08-29 2004-03-11 Roche Diagnostics Gmbh Verbesserung der Spezifität bei der Bestimmung von Antithrombin
US20050090804A1 (en) * 2003-10-22 2005-04-28 Trivascular, Inc. Endoluminal prosthesis endoleak management
DE102006035580A1 (de) * 2006-07-27 2008-02-14 Csl Behring Gmbh Bestimmung der biologischen Aktivität von Heparin in AT III-haltigen Präparationen
EP2598652A4 (de) 2010-07-29 2014-04-30 Shire Human Genetic Therapies Tests zum nachweis von glykosaminoglykanen
US20150017672A1 (en) * 2012-02-01 2015-01-15 Shire Human Genetic Therapies Inc. Assays for detection of glycosaminoglycans
CN102690862B (zh) * 2012-06-08 2015-01-28 上海太阳生物技术有限公司 抗凝血酶ⅲ(at-ⅲ)测定试剂盒(发色底物法)
ES2442246B1 (es) * 2012-08-07 2015-03-18 Fundacion Para La Formacion E Investigacion Sanitarias De La Region De Murcia Método de cuantificación de la glicoforma beta de antitrombina
CN103604766A (zh) * 2013-11-25 2014-02-26 牡丹江友搏药业股份有限公司 一种疏血通注射液的生物学质控方法
CN106153612A (zh) * 2015-12-04 2016-11-23 上海贞元诊断用品科技有限公司 抗凝血酶活性检测试剂及其制备方法和应用
CN112662735B (zh) * 2020-12-28 2022-10-14 北京美创新跃医疗器械有限公司 一种抗凝血酶ⅲ活性测定试剂盒及其制备方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4473639A (en) * 1982-09-15 1984-09-25 Miles Laboratories, Inc. Reagent strip test for antithrombin-III
CA1254119A (en) * 1984-07-20 1989-05-16 Lloyd A. Schick Single step protease inhibitor assay
NO164991C (no) * 1984-09-21 1990-12-05 Boehringer Ingelheim Int Fremgangsmaate for fremstilling av blodkoaguleringshemmende proteiner.
US4948724A (en) * 1985-09-05 1990-08-14 Yin E Thye Composition, kit and method for assaying heparin and a method for making the composition
DE3531778A1 (de) 1985-09-06 1987-03-12 Behringwerke Ag Verfahren zur bestimmung von proteaseinhibitoren
US5248596A (en) * 1987-02-25 1993-09-28 Miles Inc. Method of detecting proteolytically modified antithrombin
EP0360871B2 (de) * 1988-03-03 1999-06-30 Nippon Shoji Kabushiki Kaisha Verfahren zum messen der biologischen wirkung von antithrombin iii und reagenzkit zu dessen messung
US5221614A (en) * 1988-03-03 1993-06-22 Nippon Shoji Kabushiki Kaisha Method and reagent for determining the biological activity of antithrombin III by measuring coagulation time
US5320945A (en) * 1989-07-14 1994-06-14 Boehringer Mannheim Gmbh Method and reagent for the determination of antithrombin III
DE3923340A1 (de) * 1989-07-14 1991-01-24 Boehringer Mannheim Gmbh Verfahren und reagenz zur bestimmung von antithrombin iii

Also Published As

Publication number Publication date
DE69427115D1 (de) 2001-05-23
EP0657547A4 (de) 1997-12-10
US5646007A (en) 1997-07-08
EP0657547A1 (de) 1995-06-14
EP0657547B1 (de) 2001-04-18
WO1995000663A1 (fr) 1995-01-05
JPH078298A (ja) 1995-01-13

Similar Documents

Publication Publication Date Title
DE69409513D1 (de) Verfahren zur geometrischen messung
DE69132170T2 (de) Verfahren zur Abstandsmessung
DE68929525D1 (de) Verfahren zur Messung von Verunreinigungen
DE69228376D1 (de) Verfahren zur messung der kanalverzögerung
DE69327709T2 (de) Verfahren zur akustischen Positionsanzeige für sichtbare Objekte
DE69330649T2 (de) Verfahren zur Messung von glykosiliertem Hämoglobin
DE3579486D1 (de) Verfahren zur messwertanzeige.
DE69309889T2 (de) Verfahren zur erkennung von fehlzündungen
DE69617773D1 (de) Verfahren zur Messung von Oligonukleotidabbau
DE59400559D1 (de) Verfahren zur überprüfung der konvertierungsfähigkeit eines katalysators
DE59306925D1 (de) Geophysikalisches Verfahren zur Überwachung eines Gebiets
DE69427115T2 (de) Verfahren zur messung der antithrombin-iii-aktivität
DE59404052D1 (de) Verfahren zur überprüfung der konvertierungsfähigkeit eines katalysators
DE59407449D1 (de) Spektroskopisches Verfahren zur Messung kleinster spezifischer Absorptionssignale
DE69713842T2 (de) Verfahren zur Messung der Position von optischen Transmissionselementen
DE69735401D1 (de) Verfahren zur Messung der Intensität eines einen Körper durchdringenden Strahlenbündel
DE59103053D1 (de) Verfahren zur einstellung eines funktionsmasses.
DE69320661T2 (de) Verfahren zur messung von heparin
DE69313413T2 (de) Verfahren zur messung der radioaktivitaet
DE69724375D1 (de) Verfahren zur Messung der Polynukleotidkonzentration
DE69426223T2 (de) Verfahren und Reagenz zur Messung der Komplementaktivität
DE69800738D1 (de) Verfahren zur Messung des Säuregehalts
DE69115575T2 (de) Verfahren zur spektralen Messung
DE69127255D1 (de) Verfahren zur Messung von menschlichem C-Peptid
DE58900700D1 (de) Verfahren zur ermittlung eines durchschusszeitpunktes.

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee