DE69427820T2 - Zusammensetzungen zur nasalen verabreichung von desmopressin - Google Patents

Zusammensetzungen zur nasalen verabreichung von desmopressin

Info

Publication number
DE69427820T2
DE69427820T2 DE69427820T DE69427820T DE69427820T2 DE 69427820 T2 DE69427820 T2 DE 69427820T2 DE 69427820 T DE69427820 T DE 69427820T DE 69427820 T DE69427820 T DE 69427820T DE 69427820 T2 DE69427820 T2 DE 69427820T2
Authority
DE
Germany
Prior art keywords
composition
desmopressin
nasal administration
container
assembly
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69427820T
Other languages
English (en)
Other versions
DE69427820D1 (de
Inventor
Alan Harris
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ferring BV
Original Assignee
Ferring BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ferring BV filed Critical Ferring BV
Publication of DE69427820D1 publication Critical patent/DE69427820D1/de
Application granted granted Critical
Publication of DE69427820T2 publication Critical patent/DE69427820T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A61K38/095—Oxytocins; Vasopressins; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/12—Antidiuretics, e.g. drugs for diabetes insipidus
DE69427820T 1993-06-29 1994-06-22 Zusammensetzungen zur nasalen verabreichung von desmopressin Expired - Lifetime DE69427820T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US8489493A 1993-06-29 1993-06-29
PCT/SE1994/000623 WO1995001183A1 (en) 1993-06-29 1994-06-22 Compositions for nasal administration of desmopressin

Publications (2)

Publication Number Publication Date
DE69427820D1 DE69427820D1 (de) 2001-08-30
DE69427820T2 true DE69427820T2 (de) 2001-11-08

Family

ID=22187889

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69427820T Expired - Lifetime DE69427820T2 (de) 1993-06-29 1994-06-22 Zusammensetzungen zur nasalen verabreichung von desmopressin

Country Status (20)

Country Link
US (1) US5498598A (de)
EP (1) EP0708657B1 (de)
JP (1) JPH09502425A (de)
KR (1) KR100193104B1 (de)
CN (1) CN1101701C (de)
AT (1) ATE203412T1 (de)
CA (1) CA2166312C (de)
CZ (1) CZ282456B6 (de)
DE (1) DE69427820T2 (de)
DK (1) DK0708657T3 (de)
ES (1) ES2158898T3 (de)
GR (1) GR3036936T3 (de)
HK (1) HK1000906A1 (de)
HU (1) HU221617B1 (de)
NZ (1) NZ268442A (de)
PL (1) PL176317B1 (de)
PT (1) PT708657E (de)
RU (1) RU2135204C1 (de)
SK (1) SK282844B6 (de)
WO (1) WO1995001183A1 (de)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2149880T3 (es) * 1993-06-29 2000-11-16 Ferring Bv Sintesis de peptidos ciclicos.
US5482931A (en) * 1993-06-29 1996-01-09 Ferring Ab Stabilized pharmaceutical peptide compositions
US5674850A (en) * 1993-12-23 1997-10-07 Ferring Ab High purity desmopressin produced in large single batches
SE9400918L (sv) * 1994-03-18 1995-09-19 Anne Fjellstad Paulsen Stabiliserad komposition för oral administrering av peptider
US5763398A (en) * 1996-06-20 1998-06-09 Ferring B.V. Nasal administration of desmopressin
US5916582A (en) * 1996-07-03 1999-06-29 Alza Corporation Aqueous formulations of peptides
GB9614235D0 (en) * 1996-07-06 1996-09-04 Danbiosyst Uk Composition for enhanced uptake of polar drugs from mucosal surfaces
US5922680A (en) * 1996-10-23 1999-07-13 Ferring, B.V. Stabilized composition for oral administration of peptides
US8765177B2 (en) * 1997-09-12 2014-07-01 Columbia Laboratories, Inc. Bioadhesive progressive hydration tablets
US7153845B2 (en) * 1998-08-25 2006-12-26 Columbia Laboratories, Inc. Bioadhesive progressive hydration tablets
JP2001233787A (ja) 2000-02-04 2001-08-28 Patents Exploitation Co Bv 小・中サイズのペプチド含有薬学的組成物
US6641799B2 (en) 2002-04-03 2003-11-04 Nos Spray, Inc. Nasal spray for decongesting nasal passages
GB0210397D0 (en) * 2002-05-07 2002-06-12 Ferring Bv Pharmaceutical formulations
AU2003269747A1 (en) * 2002-05-15 2003-12-02 Sun Pharmaceutical Industries Limited A stable aqueous composition of a peptide
ES2260563T3 (es) * 2003-11-13 2006-11-01 Ferring B.V. Paquete de blister y forma farmaceutica solida para ello.
SE528446C2 (sv) * 2006-03-02 2006-11-14 Ferring Int Ct Sa Farmaceutisk sammansättning innefattande desmopressin, kiseldioxid och stärkelse
EP2197532A1 (de) 2007-08-06 2010-06-23 Serenity Pharmaceuticals Corporation Verfahren und vorrichtungen zur abgabe eines desmorpressin-arzneimittels
CN101372504B (zh) * 2007-08-22 2011-05-18 深圳翰宇药业股份有限公司 一种纯化去氨加压素的方法
HUE046050T2 (hu) 2008-05-21 2020-01-28 Ferring Bv Orodiszperzibilis dezmopresszin az alvás noktúria által meg nem zavart kezdeti szakaszának megnövelésére
US20100286045A1 (en) 2008-05-21 2010-11-11 Bjarke Mirner Klein Methods comprising desmopressin
AU2015261630B2 (en) * 2008-12-22 2017-09-14 Acerus Pharmaceuticals USA, LLC Intranasal desmopressin administration
SG10201509152VA (en) * 2008-12-22 2015-12-30 Allergan Inc Intranasal desmopressin administration
WO2010075327A1 (en) * 2008-12-22 2010-07-01 Serenity Pharmaceuticals Corporation Desmopressin composition
DK2442821T3 (en) 2009-06-18 2017-10-02 Allergan Inc SECURE ADMINISTRATION OF DESMOPRESSIN
CN102440957B (zh) * 2011-12-16 2013-09-25 深圳市健元医药科技有限公司 醋酸特利加压素鼻腔喷雾剂及其制备方法
CN112675178A (zh) 2014-12-22 2021-04-20 速达制药有限公司 预防和治疗血小板增多的癌症患者中的转移性疾病

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4271068A (en) * 1968-05-10 1981-06-02 Ciba-Geigy Corporation Process for the manufacture of cystine-containing peptides
CH517705A (de) * 1969-12-16 1972-01-15 Ciba Geigy Ag Verfahren zur Herstellung von Cystin-haltigen Peptiden
US3929758A (en) * 1974-09-12 1975-12-30 Armour Pharma Cyclization of cysteine-containing peptides
US4033940A (en) * 1975-11-12 1977-07-05 Armour Pharmaceutical Company Cyclization of peptides
US4093610A (en) * 1977-01-31 1978-06-06 American Home Products Corporation Process for producing triglycyl-lysine vasopressin and intermediates therefor
US4216141A (en) * 1978-07-19 1980-08-05 The Salk Institute For Biological Studies Method for cyclization of peptides
DE2923787A1 (de) * 1979-06-12 1980-12-18 Max Planck Gesellschaft Verfahren zur selektiven bildung von disulfidbruecken in polypeptiden und die dabei erhaltenen produkte als wirkstoffe enthaltende arzneimittel
IE56021B1 (en) * 1982-10-13 1991-03-27 Akzo Nv Peptides
JPS61194034A (ja) * 1985-02-25 1986-08-28 Teijin Ltd 経鼻投与用粉末状組成物
EP0300036A4 (de) * 1987-01-30 1989-06-14 Biomed Res Consultants Ltd Auf vasopressin basierte arzneimittelzubereitungen.
US5066716A (en) * 1988-12-13 1991-11-19 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Synthesis of chloroacetyl and bromoacetyl modified peptides for the preparation of synthetic peptide polymers, conjugated peptides, and cyclic peptides
ATE108326T1 (de) * 1989-01-30 1994-07-15 Corint Ltd Wässerige desmopressin-cmc enthaltende arzneizubereitung.
DE69001991T2 (de) * 1989-11-16 1993-09-23 Phidea Spa Fluessige arzneimittel zur nasalen anwendung, die ein polypeptid als wirksubstanz enthalten.

Also Published As

Publication number Publication date
KR960703339A (ko) 1996-08-17
SK282844B6 (sk) 2002-12-03
NZ268442A (en) 1996-09-25
HK1000906A1 (en) 2002-03-08
JPH09502425A (ja) 1997-03-11
CA2166312C (en) 2002-04-23
EP0708657B1 (de) 2001-07-25
HU221617B1 (hu) 2002-12-28
DK0708657T3 (da) 2001-10-15
PL312204A1 (en) 1996-04-01
HUT73776A (en) 1996-09-30
CZ339095A3 (en) 1996-09-11
DE69427820D1 (de) 2001-08-30
CA2166312A1 (en) 1995-01-12
EP0708657A1 (de) 1996-05-01
ATE203412T1 (de) 2001-08-15
ES2158898T3 (es) 2001-09-16
PT708657E (pt) 2001-11-30
GR3036936T3 (en) 2002-01-31
RU2135204C1 (ru) 1999-08-27
US5498598A (en) 1996-03-12
KR100193104B1 (ko) 1999-06-15
HU9503833D0 (en) 1996-02-28
PL176317B1 (pl) 1999-05-31
WO1995001183A1 (en) 1995-01-12
SK165095A3 (en) 1996-11-06
CN1101701C (zh) 2003-02-19
CZ282456B6 (cs) 1997-07-16
CN1126439A (zh) 1996-07-10

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Legal Events

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