DE69431120T2 - Verfahren ii - Google Patents

Verfahren ii

Info

Publication number
DE69431120T2
DE69431120T2 DE69431120T DE69431120T DE69431120T2 DE 69431120 T2 DE69431120 T2 DE 69431120T2 DE 69431120 T DE69431120 T DE 69431120T DE 69431120 T DE69431120 T DE 69431120T DE 69431120 T2 DE69431120 T2 DE 69431120T2
Authority
DE
Germany
Prior art keywords
agglomerates
powder
procedure
spheronizing
breath
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69431120T
Other languages
English (en)
Other versions
DE69431120D1 (de
Inventor
Eva Trofast
Magnus Olsson
Claes Ahlneck
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AstraZeneca AB
Original Assignee
AstraZeneca AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from SE9303215A external-priority patent/SE9303215D0/xx
Priority claimed from SE9304270A external-priority patent/SE9304270D0/xx
Application filed by AstraZeneca AB filed Critical AstraZeneca AB
Publication of DE69431120D1 publication Critical patent/DE69431120D1/de
Application granted granted Critical
Publication of DE69431120T2 publication Critical patent/DE69431120T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2/00—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
    • B01J2/20—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic by expressing the material, e.g. through sieves and fragmenting the extruded length
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
DE69431120T 1993-10-01 1994-09-29 Verfahren ii Expired - Lifetime DE69431120T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE9303215A SE9303215D0 (sv) 1993-10-01 1993-10-01 Process II
SE9304270A SE9304270D0 (sv) 1993-12-22 1993-12-22 Process II
PCT/SE1994/000897 WO1995009616A1 (en) 1993-10-01 1994-09-29 Process ii

Publications (2)

Publication Number Publication Date
DE69431120D1 DE69431120D1 (de) 2002-09-05
DE69431120T2 true DE69431120T2 (de) 2002-11-28

Family

ID=26661852

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69431120T Expired - Lifetime DE69431120T2 (de) 1993-10-01 1994-09-29 Verfahren ii

Country Status (28)

Country Link
US (1) US6371171B1 (de)
EP (1) EP0721332B1 (de)
JP (1) JPH09504225A (de)
KR (1) KR100347497B1 (de)
CN (1) CN1119992C (de)
AT (1) ATE221371T1 (de)
AU (1) AU687896B2 (de)
BR (1) BR9407687A (de)
CA (1) CA2172055C (de)
CZ (1) CZ289394B6 (de)
DE (1) DE69431120T2 (de)
DK (1) DK0721332T3 (de)
EG (1) EG21071A (de)
ES (1) ES2178655T3 (de)
FI (1) FI117318B (de)
HU (1) HU226493B1 (de)
IL (1) IL111081A (de)
IS (1) IS1736B (de)
NO (1) NO316747B1 (de)
NZ (1) NZ274278A (de)
PL (1) PL175596B1 (de)
PT (1) PT721332E (de)
RU (1) RU2170083C2 (de)
SG (1) SG75091A1 (de)
SK (1) SK283554B6 (de)
TW (1) TW374728B (de)
UA (1) UA42736C2 (de)
WO (1) WO1995009616A1 (de)

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DE4425255A1 (de) 1994-07-16 1996-01-18 Asta Medica Ag Formulierung zur inhalativen Applikation
US5983956A (en) * 1994-10-03 1999-11-16 Astra Aktiebolag Formulation for inhalation
US5980949A (en) * 1994-10-03 1999-11-09 Astra Aktiebolag Formulation for inhalation
SE9700134D0 (sv) * 1997-01-20 1997-01-20 Astra Ab New formulation
US5826633A (en) 1996-04-26 1998-10-27 Inhale Therapeutic Systems Powder filling systems, apparatus and methods
SE9700133D0 (sv) * 1997-01-20 1997-01-20 Astra Ab New formulation
SE9700135D0 (sv) * 1997-01-20 1997-01-20 Astra Ab New formulation
US6503537B2 (en) 1997-03-20 2003-01-07 Schering Corporation Preparation of powder agglomerates
US6495167B2 (en) * 1997-03-20 2002-12-17 Schering Corporation Preparation of powder agglomerates
KR100386055B1 (ko) 1997-03-20 2003-06-09 쉐링 코포레이션 분말 응집물의 제조방법
US6182712B1 (en) 1997-07-21 2001-02-06 Inhale Therapeutic Systems Power filling apparatus and methods for their use
EP0938923B1 (de) * 1998-02-27 2005-03-16 Sandvik Aktiebolag Verfahren und Vorrichtung zum tropfenförmigen Aufbringen fliessfähiger Massen auf ein Transportband
US6623760B1 (en) 1999-01-28 2003-09-23 Schering Corporation Method of preparing particles for agglomeration
EP1169053A1 (de) 1999-04-13 2002-01-09 Inhale Therapeutic Systems, Inc. Verabreichung von trockenpulverformulierungen über die lungen zur behandlung der unfruchtbarkeit
IL149085A0 (en) 1999-10-29 2002-11-10 Inhale Therapeutic Syst A dry powder composition containing a di or tripeptide
WO2002096549A1 (en) * 2001-05-29 2002-12-05 Spheriform Pty Ltd Agglomeration of fine particulate material
ES2364636T3 (es) 2001-12-19 2011-09-08 Novartis Ag Administración pulmonar de aminoglucósidos.
PT1699434E (pt) * 2003-09-02 2011-05-03 Norton Healthcare Ltd Processo para a prepara??o de um medicamento
EP1701714A2 (de) 2004-01-07 2006-09-20 Nektar Therapeutics Verbesserte zusammensetzungen mit verzögerter freisetzung für die pulmonale verabreichung von insulin
SG153833A1 (en) 2004-06-18 2009-07-29 Novartis Vaccines & Diagnostic Methods of treatment of endobronchial infections
CN101239330B (zh) * 2007-02-09 2010-10-27 中国石油化工股份有限公司 微球形催化剂载体的制备方法
AU2008317307A1 (en) * 2007-10-25 2009-04-30 Novartis Ag Powder conditioning of unit dose drug packages
AU2009292643B2 (en) 2008-09-19 2016-02-18 Nektar Therapeutics Polymer conjugates of therapeutic peptides
JP5668317B2 (ja) * 2009-04-24 2015-02-12 大正製薬株式会社 プソイドエフェドリン含有製剤粒子
GB201305825D0 (en) 2013-03-28 2013-05-15 Vectura Ltd New use
KR20220066906A (ko) * 2019-09-24 2022-05-24 키에시 파르마슈티시 엣스. 피. 에이. 흡입용 건조 분말 제제를 위한 신규 담체 입자

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GB1242211A (en) 1967-08-08 1971-08-11 Fisons Pharmaceuticals Ltd Pharmaceutical composition
DE2350746C3 (de) * 1973-10-10 1978-08-31 Guenther Papenmeier Gmbh & Co Kg Maschinen- Und Apparatebau, 4930 Detmold Verfahren und Vorrichtungen zur Herstellung von Granulaten aus pulverformigem, körnigem oder teigigem Gut
GB1520247A (en) 1974-08-10 1978-08-02 Fisons Ltd Pelletised medicament formulations
GB1569611A (en) 1976-01-23 1980-06-18 Fisons Ltd Pelletised or granular medicament formulation
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EP0072046B1 (de) * 1981-07-24 1986-01-15 FISONS plc Inhalierbare Arzneimittel, Verfahren zu deren Herstellung und pharmazeutische Formulierungen diese enthaltend
PL135587B1 (en) * 1982-08-16 1985-11-30 Zabrzanska Fabryka Maszyn Gorniczych "Powen" Centrifugal dewatering screen
US4495308A (en) * 1983-03-04 1985-01-22 Chevron Research Company Two-region spherical catalysts
US4605173A (en) * 1984-04-04 1986-08-12 Edmonds Harvey A Size reduction machine
US4689297A (en) * 1985-03-05 1987-08-25 Miles Laboratories, Inc. Dust free particulate enzyme formulation
US4688610A (en) 1985-03-19 1987-08-25 Spiral Systems Inc. Apparatus for dispensing particulate agglomerating solids
US4655701A (en) * 1986-02-19 1987-04-07 Fuji Paudal Kabushiki Kaisha Granulating apparatus
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DE4105984A1 (de) 1991-02-26 1992-08-27 Deutsche Forsch Luft Raumfahrt Verfahren zur aufbereitung pulverfoermiger rohstoffe
US5262172A (en) * 1992-06-19 1993-11-16 Digestive Care Inc. Compositions of gastric acid-resistant microspheres containing buffered bile acids
US5399358A (en) * 1993-11-12 1995-03-21 Edward Mendell Co., Inc. Sustained release formulations for 24 hour release of metroprolol

Also Published As

Publication number Publication date
RU2170083C2 (ru) 2001-07-10
DK0721332T3 (da) 2002-09-02
IS4214A (is) 1995-04-02
BR9407687A (pt) 1997-02-04
UA42736C2 (uk) 2001-11-15
IL111081A (en) 1998-12-06
FI117318B (fi) 2006-09-15
NO961291D0 (no) 1996-03-29
PL313766A1 (en) 1996-07-22
IL111081A0 (en) 1994-11-28
ATE221371T1 (de) 2002-08-15
HU226493B1 (en) 2009-03-02
CN1119992C (zh) 2003-09-03
NZ274278A (en) 1997-07-27
SK283554B6 (sk) 2003-09-11
US6371171B1 (en) 2002-04-16
KR100347497B1 (ko) 2002-12-26
TW374728B (en) 1999-11-21
PT721332E (pt) 2002-10-31
NO316747B1 (no) 2004-04-26
NO961291L (no) 1996-03-29
WO1995009616A1 (en) 1995-04-13
AU7826294A (en) 1995-05-01
JPH09504225A (ja) 1997-04-28
EG21071A (en) 2000-10-31
IS1736B (is) 1999-12-30
ES2178655T3 (es) 2003-01-01
HU9600823D0 (en) 1996-05-28
FI961431A (fi) 1996-03-29
CZ94196A3 (en) 1996-06-12
FI961431A0 (fi) 1996-03-29
DE69431120D1 (de) 2002-09-05
CN1132477A (zh) 1996-10-02
HUT74518A (en) 1997-01-28
PL175596B1 (pl) 1999-01-29
CA2172055A1 (en) 1995-04-13
EP0721332A1 (de) 1996-07-17
CZ289394B6 (cs) 2002-01-16
SG75091A1 (en) 2000-09-19
EP0721332B1 (de) 2002-07-31
CA2172055C (en) 2005-11-08
AU687896B2 (en) 1998-03-05
SK39296A3 (en) 1997-06-04

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