DE69432122D1 - Verfahren und vorrichtung zum nachweis von hämolysis in flüssigen proben - Google Patents

Verfahren und vorrichtung zum nachweis von hämolysis in flüssigen proben

Info

Publication number
DE69432122D1
DE69432122D1 DE69432122T DE69432122T DE69432122D1 DE 69432122 D1 DE69432122 D1 DE 69432122D1 DE 69432122 T DE69432122 T DE 69432122T DE 69432122 T DE69432122 T DE 69432122T DE 69432122 D1 DE69432122 D1 DE 69432122D1
Authority
DE
Germany
Prior art keywords
hemolysis
detecting hemolysis
elevation
liquid samples
determining
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69432122T
Other languages
English (en)
Other versions
DE69432122T2 (de
Inventor
Graham Davis
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Point of Care Inc
Original Assignee
iStat Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by iStat Corp filed Critical iStat Corp
Application granted granted Critical
Publication of DE69432122D1 publication Critical patent/DE69432122D1/de
Publication of DE69432122T2 publication Critical patent/DE69432122T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/72—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood pigments, e.g. haemoglobin, bilirubin or other porphyrins; involving occult blood
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/72—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood pigments, e.g. haemoglobin, bilirubin or other porphyrins; involving occult blood
    • G01N33/721—Haemoglobin
    • G01N33/726—Devices
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/72—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood pigments, e.g. haemoglobin, bilirubin or other porphyrins; involving occult blood
    • G01N33/721—Haemoglobin
    • G01N33/725—Haemoglobin using peroxidative activity
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/25125—Digestion or removing interfering materials
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/25375—Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.]
DE69432122T 1993-10-04 1994-09-28 Verfahren und vorrichtung zum nachweis von hämolysis in flüssigen proben Expired - Lifetime DE69432122T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/131,527 US5416026A (en) 1993-10-04 1993-10-04 Method for detecting the change in an analyte due to hemolysis in a fluid sample
PCT/US1994/010588 WO1995010044A1 (en) 1993-10-04 1994-09-28 A method and apparatus for detecting hemolysis in a fluid sample

Publications (2)

Publication Number Publication Date
DE69432122D1 true DE69432122D1 (de) 2003-03-20
DE69432122T2 DE69432122T2 (de) 2003-10-16

Family

ID=22449838

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69432122T Expired - Lifetime DE69432122T2 (de) 1993-10-04 1994-09-28 Verfahren und vorrichtung zum nachweis von hämolysis in flüssigen proben

Country Status (10)

Country Link
US (2) US5416026A (de)
EP (1) EP0722569B1 (de)
JP (1) JP3527741B2 (de)
KR (1) KR100247327B1 (de)
CN (1) CN1135260A (de)
AT (1) ATE232606T1 (de)
AU (1) AU696428B2 (de)
CA (1) CA2173461A1 (de)
DE (1) DE69432122T2 (de)
WO (1) WO1995010044A1 (de)

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FR2733835B1 (fr) * 1995-05-03 1997-07-18 Hycel Groupe Lisabio Procede et dispositif de detection du point de lyse de globules rouges
EP0872032B1 (de) * 1995-05-18 2003-11-26 Aura Communications, Inc. Magnetische kommunikationssystem mit geringer reichweite
US7198955B1 (en) * 1997-03-03 2007-04-03 Nir Diagnostics Inc. Method and apparatus for measurement of blood substitutes
US6177283B1 (en) * 1997-05-28 2001-01-23 Flexsite Diagnostics, Inc. Diagnostic assay
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US5919711A (en) * 1997-08-07 1999-07-06 Careside, Inc. Analytical cartridge
US6002475A (en) * 1998-01-28 1999-12-14 Careside, Inc. Spectrophotometric analytical cartridge
WO1999036778A1 (en) 1998-01-20 1999-07-22 University Of Victoria Innovation & Development Corporation Detection of gpi anchored proteins
US6531095B2 (en) 1999-02-11 2003-03-11 Careside, Inc. Cartridge-based analytical instrument with optical detector
US6391264B2 (en) 1999-02-11 2002-05-21 Careside, Inc. Cartridge-based analytical instrument with rotor balance and cartridge lock/eject system
US6348176B1 (en) 1999-02-11 2002-02-19 Careside, Inc. Cartridge-based analytical instrument using centrifugal force/pressure for metering/transport of fluids
US6623972B2 (en) * 2000-06-09 2003-09-23 Bayer Corporation Automated method for detecting, quantifying and monitoring exogenous hemoglobin in whole blood, plasma and serum
US7214300B2 (en) * 2001-06-04 2007-05-08 Epocal Inc. Integrated electrokinetic devices and methods of manufacture
US6896778B2 (en) * 2001-06-04 2005-05-24 Epocal Inc. Electrode module
US6797236B2 (en) * 2002-01-14 2004-09-28 Infineon Technologies Ag Design and signal recovery of biomolecular sensor arrays
US20040018577A1 (en) * 2002-07-29 2004-01-29 Emerson Campbell John Lewis Multiple hybrid immunoassay
US7767068B2 (en) * 2002-12-02 2010-08-03 Epocal Inc. Heterogeneous membrane electrodes
US7842234B2 (en) * 2002-12-02 2010-11-30 Epocal Inc. Diagnostic devices incorporating fluidics and methods of manufacture
US7261861B2 (en) * 2003-04-24 2007-08-28 Haemoscope Corporation Hemostasis analyzer and method
US7920906B2 (en) 2005-03-10 2011-04-05 Dexcom, Inc. System and methods for processing analyte sensor data for sensor calibration
US7722817B2 (en) * 2003-08-28 2010-05-25 Epocal Inc. Lateral flow diagnostic devices with instrument controlled fluidics
US9247900B2 (en) 2004-07-13 2016-02-02 Dexcom, Inc. Analyte sensor
US20060270922A1 (en) 2004-07-13 2006-11-30 Brauker James H Analyte sensor
US20060020192A1 (en) 2004-07-13 2006-01-26 Dexcom, Inc. Transcutaneous analyte sensor
GB0503836D0 (en) * 2005-02-24 2005-04-06 Axis Shield Asa Method
US7879615B2 (en) * 2005-10-20 2011-02-01 Coramed Technologies, Llc Hemostasis analyzer and method
JP2009526232A (ja) * 2006-02-08 2009-07-16 ベクトン・ディキンソン・アンド・カンパニー 改良されたラベル処理装置及びそれに関連する方法
US7790464B2 (en) * 2006-05-04 2010-09-07 Blaze Medical Devices, LLC Blood hemolysis analyzer
JP5156738B2 (ja) * 2006-06-06 2013-03-06 エフ．ホフマン−ラ ロシュ アーゲー 全血試料の特異的溶血
SE530596C2 (sv) * 2006-10-13 2008-07-15 Mathias Karlsson Metod att fastställa syrebrist i blod från skalpen under förlossning
US8445199B2 (en) * 2008-12-31 2013-05-21 Abbott Point Of Care Inc. Method and device for immunoassay using nucleotide conjugates
US8084223B2 (en) * 2009-03-23 2011-12-27 Siemens Healthcare Diagnostics Inc. Detection of false results in assays
US20110001103A1 (en) * 2009-07-01 2011-01-06 Chi-Kuang Chen Elevating mechanism for measuring concentrations of medicines
US8973293B2 (en) 2010-11-19 2015-03-10 Becton, Dickinson And Company Specimen container label for automated clinical laboratory processing systems
WO2012075258A2 (en) 2010-12-03 2012-06-07 Abbott Point Of Care Inc. Ratiometric immunoassay method and blood testing device
US9050595B2 (en) 2010-12-03 2015-06-09 Abbott Point Of Care Inc. Assay devices with integrated sample dilution and dilution verification and methods of using same
CN103282125B (zh) 2010-12-03 2015-05-20 雅培医护站股份有限公司 具有整合的样品稀释的样品计量装置和测定装置
US9061283B2 (en) 2010-12-03 2015-06-23 Abbott Point Of Care Inc. Sample metering device and assay device with integrated sample dilution
CN103518134A (zh) * 2011-02-15 2014-01-15 松村鹰仁 尿检板
JP5986089B2 (ja) * 2011-08-24 2016-09-06 栄研化学株式会社 白血球測定デバイス及び試薬キット
US9625465B2 (en) 2012-05-15 2017-04-18 Defined Diagnostics, Llc Clinical diagnostic systems
US9213043B2 (en) 2012-05-15 2015-12-15 Wellstat Diagnostics, Llc Clinical diagnostic system including instrument and cartridge
US9081001B2 (en) 2012-05-15 2015-07-14 Wellstat Diagnostics, Llc Diagnostic systems and instruments
EP3581925A1 (de) * 2013-03-14 2019-12-18 Instrumentation Laboratory Company Vollbluthämolysesensor
JP6166938B2 (ja) * 2013-04-18 2017-07-19 ローム株式会社 マイクロチップ
CN104655596A (zh) * 2013-11-18 2015-05-27 李捷 一种含红细胞血液样品的质量检测方法及检测试剂盒
US20170108516A1 (en) * 2014-06-13 2017-04-20 Siemens Healthcare Diagnostics Inc. Detection of hemolysis using a chromatographic detection pad
DK3201624T3 (da) * 2014-09-30 2020-06-02 Siemens Healthcare Diagnostics Inc Indretning til detektion af hæmolyse, system og fremgangsmåde
US9547899B1 (en) * 2014-10-07 2017-01-17 University Of South Florida Mobile hemolysis detection in whole blood samples
EP3234570B1 (de) * 2014-12-19 2022-08-31 Siemens Healthcare Diagnostics Inc. Hämolysenachweis unter verwendung intrazellulärer analytkonzentrationen
CN109313115B (zh) 2016-05-11 2022-04-12 诺尔生物医药有限公司 全血so2传感器
EP3665479B1 (de) * 2017-08-09 2022-09-14 Joanneum Research Forschungsgesellschaft mbH Vorrichtung für genaue messung einer physiologischen substanz im blut
CN111000566B (zh) * 2019-12-13 2021-05-11 江南大学 具有光热效应和抗菌功能的可穿戴柔性传感器
WO2024016077A1 (en) * 2022-07-19 2024-01-25 Hylid Diagnostics Inc. Point-of-care blood analysis system
GB2620968A (en) * 2022-07-28 2024-01-31 Kalium Health Ltd Sensor, apparatus, kit and method
CN116298328A (zh) * 2022-12-06 2023-06-23 北京大学第三医院（北京大学第三临床医学院） 一种用于测定溶血标本血钾浓度的试剂盒

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US3539300A (en) * 1967-10-23 1970-11-10 Schering Corp Body fluid collector and separator having improved flow rate
US3972614A (en) * 1974-07-10 1976-08-03 Radiometer A/S Method and apparatus for measuring one or more constituents of a blood sample
US4057394A (en) * 1976-05-24 1977-11-08 Miles Laboratories, Inc. Test device and method for determining blood hemoglobin
DE2847176C2 (de) * 1977-10-31 1982-05-06 Hitachi, Ltd., Tokyo Verfahren zur photometrischen Bestimmung von Substanzen im Blutserum
DE3029579C2 (de) * 1980-08-05 1985-12-12 Boehringer Mannheim Gmbh, 6800 Mannheim Verfahren und Mittel zur Abtrennung von Plasma oder Serum aus Vollblut
US4816224A (en) * 1980-08-05 1989-03-28 Boehringer Mannheim Gmbh Device for separating plasma or serum from whole blood and analyzing the same
JPS6052761A (ja) * 1983-09-01 1985-03-26 Olympus Optical Co Ltd 電解質測定方法
US4696797A (en) * 1985-04-15 1987-09-29 Environmental Diagnostics, Inc. Suspension liquid separator
EP0230645A3 (de) * 1985-12-28 1987-12-09 Fuji Photo Film Co., Ltd. Gerät zur Ionenaktivitätsmessung
US4761369A (en) * 1986-05-12 1988-08-02 David Diagnostics, Inc. Process for measuring calcium levels in biological fluids
JPS6350743A (ja) * 1986-08-20 1988-03-03 Hitachi Ltd 溶血のある血液試料の分析方法
US4753776A (en) * 1986-10-29 1988-06-28 Biotrack, Inc. Blood separation device comprising a filter and a capillary flow pathway exiting the filter
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DE4015589A1 (de) * 1990-05-15 1991-11-21 Boehringer Mannheim Gmbh Vorrichtung und deren verwendung zur abtrennung von plasma aus vollblut
US5186843A (en) * 1991-07-22 1993-02-16 Ahlstrom Filtration, Inc. Blood separation media and method for separating plasma from whole blood
US5223219A (en) * 1992-04-10 1993-06-29 Biotrack, Inc. Analytical cartridge and system for detecting analytes in liquid samples

Also Published As

Publication number Publication date
CA2173461A1 (en) 1995-04-13
EP0722569B1 (de) 2003-02-12
JP3527741B2 (ja) 2004-05-17
AU696428B2 (en) 1998-09-10
ATE232606T1 (de) 2003-02-15
JPH09504608A (ja) 1997-05-06
US5593638A (en) 1997-01-14
DE69432122T2 (de) 2003-10-16
KR100247327B1 (ko) 2000-06-01
KR960705213A (ko) 1996-10-09
US5416026A (en) 1995-05-16
AU7875894A (en) 1995-05-01
EP0722569A4 (de) 2000-10-18
CN1135260A (zh) 1996-11-06
WO1995010044A1 (en) 1995-04-13
EP0722569A1 (de) 1996-07-24

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8364 No opposition during term of opposition