DE69500580T2 - Vorrichtung zur Echtzeitanalyse von Polynucleotidfragmenten durch fluoreszierende Abtastelektrophorese - Google Patents

Vorrichtung zur Echtzeitanalyse von Polynucleotidfragmenten durch fluoreszierende Abtastelektrophorese

Info

Publication number
DE69500580T2
DE69500580T2 DE69500580T DE69500580T DE69500580T2 DE 69500580 T2 DE69500580 T2 DE 69500580T2 DE 69500580 T DE69500580 T DE 69500580T DE 69500580 T DE69500580 T DE 69500580T DE 69500580 T2 DE69500580 T2 DE 69500580T2
Authority
DE
Germany
Prior art keywords
electrophoresis
polynucleotide fragments
fluorescence
real
fluorescently
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69500580T
Other languages
English (en)
Other versions
DE69500580D1 (de
Inventor
Louis Hoff
Eric Lachenmeier
Yefim Raysberg
Eric Nordman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Applied Biosystems LLC
Original Assignee
Perkin Elmer Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Perkin Elmer Corp filed Critical Perkin Elmer Corp
Publication of DE69500580D1 publication Critical patent/DE69500580D1/de
Application granted granted Critical
Publication of DE69500580T2 publication Critical patent/DE69500580T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416Systems
    • G01N27/447Systems using electrophoresis
    • G01N27/44704Details; Accessories
    • G01N27/44717Arrangements for investigating the separated zones, e.g. localising zones
    • G01N27/44721Arrangements for investigating the separated zones, e.g. localising zones by optical means
DE69500580T 1994-02-07 1995-01-31 Vorrichtung zur Echtzeitanalyse von Polynucleotidfragmenten durch fluoreszierende Abtastelektrophorese Expired - Lifetime DE69500580T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/192,485 US5543026A (en) 1994-02-07 1994-02-07 Real-time scanning fluorescence electrophoresis apparatus for the analysis of polynucleotide fragments
PCT/US1995/001353 WO1995021377A1 (en) 1994-02-07 1995-01-31 Improved real-time scanning fluorescence electrophoresis apparatus for the analysis of polynucleotide fragments

Publications (2)

Publication Number Publication Date
DE69500580D1 DE69500580D1 (de) 1997-09-25
DE69500580T2 true DE69500580T2 (de) 1998-02-19

Family

ID=22709873

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69500580T Expired - Lifetime DE69500580T2 (de) 1994-02-07 1995-01-31 Vorrichtung zur Echtzeitanalyse von Polynucleotidfragmenten durch fluoreszierende Abtastelektrophorese

Country Status (8)

Country Link
US (1) US5543026A (de)
EP (1) EP0744023B1 (de)
JP (2) JP3003104B2 (de)
AT (1) ATE157168T1 (de)
AU (1) AU676964B2 (de)
CA (1) CA2179710C (de)
DE (1) DE69500580T2 (de)
WO (1) WO1995021377A1 (de)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5459325A (en) * 1994-07-19 1995-10-17 Molecular Dynamics, Inc. High-speed fluorescence scanner
US6001229A (en) * 1994-08-01 1999-12-14 Lockheed Martin Energy Systems, Inc. Apparatus and method for performing microfluidic manipulations for chemical analysis
US5871628A (en) * 1996-08-22 1999-02-16 The University Of Texas System Automatic sequencer/genotyper having extended spectral response
US6008379A (en) 1997-10-01 1999-12-28 The Perkin-Elmer Corporation Aromatic-substituted xanthene dyes
US6583168B1 (en) 1997-11-25 2003-06-24 Applera Corporation Sulfonated diarylrhodamine dyes
US5936087A (en) 1997-11-25 1999-08-10 The Perkin-Elmer Corporation Dibenzorhodamine dyes
US6430512B1 (en) 1997-12-30 2002-08-06 Caliper Technologies Corp. Software for the display of chromatographic separation data
US6289229B1 (en) 1998-01-20 2001-09-11 Scimed Life Systems, Inc. Readable probe array for in vivo use
US6369893B1 (en) 1998-05-19 2002-04-09 Cepheid Multi-channel optical detection system
US6096875A (en) 1998-05-29 2000-08-01 The Perlein-Elmer Corporation Nucleotide compounds including a rigid linker
EP0990896B1 (de) * 1998-09-10 2012-01-25 Wallac Oy Analysegerät für ein grossflächiges Bild
US6413780B1 (en) 1998-10-14 2002-07-02 Abbott Laboratories Structure and method for performing a determination of an item of interest in a sample
SE9804606D0 (sv) * 1998-12-30 1998-12-30 Amersham Pharm Biotech Ab Method and device for measuring labels in a carrier
US6558945B1 (en) * 1999-03-08 2003-05-06 Aclara Biosciences, Inc. Method and device for rapid color detection
US7255999B2 (en) 2001-05-21 2007-08-14 Monogram Biosciences, Inc. Methods and compositions for analyzing proteins
EP1317464B1 (de) * 2000-10-11 2009-05-13 Applera Corporation Fluoreszierende nukleobasekonjugate mit anionische linker
US20030136921A1 (en) * 2002-01-23 2003-07-24 Reel Richard T Methods for fluorescence detection that minimizes undesirable background fluorescence
US20040091850A1 (en) * 2002-11-08 2004-05-13 Travis Boone Single cell analysis of membrane molecules
US7402398B2 (en) * 2003-07-17 2008-07-22 Monogram Biosciences, Inc. Measuring receptor homodimerization
EP1673399B1 (de) * 2003-08-11 2017-04-05 Monogram BioSciences, Inc. Nachweis und erstellung des profils eines molekularen komplexes
WO2006112818A2 (en) 2005-04-14 2006-10-26 Applera Corporation 3' modified oligonucleotides containing pseudoisocytosine nucleobase derivatives and applications thereof as primers or probes
US7663750B2 (en) 2005-06-30 2010-02-16 Applied Biosystems, Llc Two-dimensional spectral imaging system
US7817273B2 (en) * 2005-06-30 2010-10-19 Life Technologies Corporation Two-dimensional spectral imaging system
US7595874B1 (en) 2006-02-08 2009-09-29 Sciperio, Inc. Method of condensed cell slide preparation and detection of rarely occurring cells on microscope slides
JP2011501132A (ja) 2007-10-10 2011-01-06 ポカード・ディアグノスティクス・リミテッド 尿中のバクテリアの同定を行うためのシステム
EP2391883B1 (de) * 2009-01-30 2018-03-07 Micronics, Inc. Tragbares hochleistungsfluoreszenznachweissystem
JP5791634B2 (ja) 2010-01-29 2015-10-07 マイクロニクス, インコーポレイテッド サンプル−回答型のマイクロ流体カートリッジ
JP5899038B2 (ja) * 2012-04-23 2016-04-06 シャープ株式会社 蛍光検出装置および蛍光検出方法
US10065186B2 (en) 2012-12-21 2018-09-04 Micronics, Inc. Fluidic circuits and related manufacturing methods
CN104919035B (zh) 2012-12-21 2017-08-11 精密公司 便携式荧光检测系统和微测定盒
EP2934751B1 (de) 2012-12-21 2019-05-29 Micronics, Inc. Filme mit geringere elastizität zur mikrofluidischen verwendung
CA2911303C (en) 2013-05-07 2021-02-16 Micronics, Inc. Methods for preparation of nucleic acid-containing samples using clay minerals and alkaline solutions
WO2014182847A1 (en) 2013-05-07 2014-11-13 Micronics, Inc. Device for preparation and analysis of nucleic acids
WO2014182844A1 (en) 2013-05-07 2014-11-13 Micronics, Inc. Microfluidic devices and methods for performing serum separation and blood cross-matching
CN108168726B (zh) * 2016-12-08 2020-10-02 中国科学院福建物质结构研究所 一种测量固体激光器中增益介质内部温度的方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CS171472B1 (de) * 1974-03-04 1976-10-29
US4683202A (en) * 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US4811218A (en) * 1986-06-02 1989-03-07 Applied Biosystems, Inc. Real time scanning electrophoresis apparatus for DNA sequencing
US4957613A (en) * 1987-02-02 1990-09-18 Life Technologies Inc. Adjustable-height vertical gel slab electrophoresis apparatus
JP2702920B2 (ja) * 1987-03-20 1998-01-26 株式会社日立製作所 電気泳動分離検出方法及び装置
JP2550106B2 (ja) * 1987-10-30 1996-11-06 株式会社日立製作所 光分散検出型電気泳動装置
US4802969A (en) * 1988-04-28 1989-02-07 Eastman Kodak Company Gel plate assembly for electrophoresis
JP2901004B2 (ja) * 1989-04-12 1999-06-02 株式会社日立製作所 Dnaの塩基配列決定法
US4975170A (en) * 1990-03-29 1990-12-04 Eastman Kodak Company Back support for an electrophoresis gel plate assembly
DE4139211C2 (de) * 1990-11-30 1994-03-24 Hitachi Ltd Elektrophoresegerät
US5162654A (en) * 1991-02-01 1992-11-10 Wisconsin Alumni Research Foundation Detection apparatus for electrophoretic gels

Also Published As

Publication number Publication date
EP0744023A1 (de) 1996-11-27
CA2179710A1 (en) 1995-08-10
US5543026A (en) 1996-08-06
EP0744023B1 (de) 1997-08-20
WO1995021377A1 (en) 1995-08-10
DE69500580D1 (de) 1997-09-25
AU676964B2 (en) 1997-03-27
ATE157168T1 (de) 1997-09-15
JP2000137022A (ja) 2000-05-16
JP3111064B2 (ja) 2000-11-20
JPH09505669A (ja) 1997-06-03
JP3003104B2 (ja) 2000-01-24
CA2179710C (en) 2000-01-18
AU1609995A (en) 1995-08-21

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: APPLERA CORP., FOSTER CITY, CALIF., US

8327 Change in the person/name/address of the patent owner

Owner name: APPLIED BIOSYSTEMS, LLC (N. D. GES. D. STAATES, US

8380 Miscellaneous part iii

Free format text: PFANDRECHT

8380 Miscellaneous part iii

Free format text: PFANDRECHT AUFGEHOBEN