DE69504584T2 - Thermostabile Trehalose-freisetzendes Enzym, seine Herstellung und Verwendung - Google Patents

Thermostabile Trehalose-freisetzendes Enzym, seine Herstellung und Verwendung

Info

Publication number
DE69504584T2
DE69504584T2 DE69504584T DE69504584T DE69504584T2 DE 69504584 T2 DE69504584 T2 DE 69504584T2 DE 69504584 T DE69504584 T DE 69504584T DE 69504584 T DE69504584 T DE 69504584T DE 69504584 T2 DE69504584 T2 DE 69504584T2
Authority
DE
Germany
Prior art keywords
trehalose
atcc
production
releasing enzyme
enzyme
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69504584T
Other languages
English (en)
Other versions
DE69504584D1 (de
Inventor
Shouji Ikegami
Michio Kubota
Toshiyuki Sugimoto
Toshio Miyake
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hayashibara Seibutsu Kagaku Kenkyujo KK
Original Assignee
Hayashibara Seibutsu Kagaku Kenkyujo KK
Hayashibara Biochemical Laboratories Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hayashibara Seibutsu Kagaku Kenkyujo KK, Hayashibara Biochemical Laboratories Co Ltd filed Critical Hayashibara Seibutsu Kagaku Kenkyujo KK
Publication of DE69504584D1 publication Critical patent/DE69504584D1/de
Application granted granted Critical
Publication of DE69504584T2 publication Critical patent/DE69504584T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01141—4-Alpha-D-{(1->4)-alpha-D-glucano} trehalose trehalohydrolase (3.2.1.141)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/60—Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q7/00—Preparations for affecting hair growth
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/12—Disaccharides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/14—Preparation of compounds containing saccharide radicals produced by the action of a carbohydrase (EC 3.2.x), e.g. by alpha-amylase, e.g. by cellulase, hemicellulase
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
DE69504584T 1994-06-25 1995-06-23 Thermostabile Trehalose-freisetzendes Enzym, seine Herstellung und Verwendung Expired - Lifetime DE69504584T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP16612694 1994-06-25
JP10913095A JP3557277B2 (ja) 1994-06-25 1995-04-11 耐熱性トレハロース遊離酵素とその製造方法並びに用途

Publications (2)

Publication Number Publication Date
DE69504584D1 DE69504584D1 (de) 1998-10-15
DE69504584T2 true DE69504584T2 (de) 1999-05-12

Family

ID=26448918

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69504584T Expired - Lifetime DE69504584T2 (de) 1994-06-25 1995-06-23 Thermostabile Trehalose-freisetzendes Enzym, seine Herstellung und Verwendung

Country Status (10)

Country Link
US (2) US5723327A (de)
EP (1) EP0688866B1 (de)
JP (1) JP3557277B2 (de)
KR (1) KR100391376B1 (de)
AT (1) ATE170920T1 (de)
AU (1) AU694213B2 (de)
CA (1) CA2151438C (de)
DE (1) DE69504584T2 (de)
DK (1) DK0688866T3 (de)
TW (1) TW507008B (de)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3557277B2 (ja) * 1994-06-25 2004-08-25 株式会社林原生物化学研究所 耐熱性トレハロース遊離酵素とその製造方法並びに用途
JP3662972B2 (ja) * 1994-06-27 2005-06-22 株式会社林原生物化学研究所 非還元性糖質とその製造方法並びに用途
JP3793590B2 (ja) * 1994-06-27 2006-07-05 株式会社林原生物化学研究所 非還元性糖質とその製造方法並びに用途
EP0693558B1 (de) * 1994-07-19 2002-12-04 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo Trehalose, ihre Herstellung und ihre Verwendung
JP3557289B2 (ja) * 1994-07-21 2004-08-25 株式会社林原生物化学研究所 非還元性糖質からトレハロースを遊離する組換え型耐熱性酵素
JP3557288B2 (ja) * 1994-07-21 2004-08-25 株式会社林原生物化学研究所 還元性澱粉糖から末端にトレハロース構造を有する非還元性糖質を生成する組換え型耐熱性酵素
NL9500292A (nl) * 1995-02-16 1996-10-01 Stichting Nl Instituut Voor Ko Werkwijze voor omzetting van een zetmeelmateriaal, en daarvoor bruikbaar enzympreparaat.
JPH11116588A (ja) 1997-10-16 1999-04-27 Hayashibara Biochem Lab Inc トレハロース及び糖アルコールの製造方法
JP4203159B2 (ja) 1997-12-09 2008-12-24 株式会社林原生物化学研究所 神経機能調節剤
JP4295840B2 (ja) * 1997-12-09 2009-07-15 株式会社林原生物化学研究所 血行改善剤
JP3958884B2 (ja) 1998-09-11 2007-08-15 株式会社林原生物化学研究所 非還元性糖質生成酵素及びトレハロース遊離酵素ならびに該酵素を用いる糖質の製造方法
JP2000262252A (ja) 1999-01-11 2000-09-26 Aoba Kasei Kk タンパク質変性抑制剤、冷凍変性が抑制された擂潰食肉およびその製造方法ならびに練り製品の製造方法
JP4652540B2 (ja) 2000-03-02 2011-03-16 株式会社林原生物化学研究所 体臭抑制剤とその用途
CA2355814C (en) * 2000-09-14 2010-06-29 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo Pharmaceutical composition for ophthalmic use
JP4982643B2 (ja) * 2000-09-14 2012-07-25 株式会社林原 眼科用医薬組成物
JP4754066B2 (ja) 2000-12-22 2011-08-24 株式会社林原生物化学研究所 抗関節障害剤
WO2004107883A1 (en) * 2003-06-05 2004-12-16 Cargill, Incorporated Beverage additive mixture of trehalose and protein
JP4601934B2 (ja) * 2003-10-06 2010-12-22 ナガセ医薬品株式会社 ユビデカレノン錠
WO2005110432A1 (ja) * 2004-05-17 2005-11-24 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo 水系環境に接する生体の生命活動を強化及び／又は生命活動好適域を拡張する方法
EP1598428A1 (de) 2004-05-18 2005-11-23 Georg Dewald Verfahren und Kits zum Nachweis von erblichen angioedema typ III
WO2006023812A1 (en) * 2004-08-20 2006-03-02 Cargill Incorporated Ingredient systems comprising trehalose, food products containing trehalose, and methods of making same
US8231925B2 (en) * 2004-08-20 2012-07-31 Cargill, Incorporated Ingredient systems comprising trehalose, food products containing trehalose, and methods of making same
JP5184768B2 (ja) * 2006-09-05 2013-04-17 株式会社林原 トレハロース高含有糖液の回収方法並びに結晶トレハロースの製造方法
WO2013042587A1 (ja) 2011-09-21 2013-03-28 株式会社林原 α，α－トレハロース二含水結晶含有粉末の製造方法
WO2019030165A1 (en) * 2017-08-08 2019-02-14 Novozymes A/S POLYPEPTIDES HAVING TREHALASE ACTIVITY AND THEIR USE IN A PRODUCTION PROCESS OF FERMENTATION PRODUCTS
WO2020053808A1 (en) 2018-09-12 2020-03-19 Georg Dewald Method of diagnosing vasoregulatory disorders
CN114032206A (zh) * 2021-11-29 2022-02-11 广东希普生物科技股份有限公司 一种酵母菌种子液的培养方法
CN114703159B (zh) * 2022-03-15 2023-05-26 林影 一种葡糖基转移酶突变体及其应用

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS50154485A (de) * 1974-05-31 1975-12-12
JPS5823799A (ja) * 1981-08-03 1983-02-12 株式会社林原生物化学研究所 高純度マルト−スの製造方法
JPS5872598A (ja) * 1981-10-26 1983-04-30 Hayashibara Biochem Lab Inc 高純度イソマルト−スの製造方法
JPS58216695A (ja) * 1982-06-07 1983-12-16 Otsuka Shokuhin Kogyo Kk トレハロ−スの製造方法
US4762857A (en) * 1986-05-30 1988-08-09 E. I. Du Pont De Nemours And Company Trehalose as stabilizer and tableting excipient
US4839164A (en) * 1987-02-24 1989-06-13 Estee Lauder, Inc. Trehalose containing cosmetic composition and method of using it
GB8715238D0 (en) * 1987-06-29 1987-08-05 Quadrant Bioresources Ltd Food process
JP3134229B2 (ja) 1990-03-08 2001-02-13 株式会社林原生物化学研究所 ラクトスクロース高含有粉末の製造方法とその粉末の用途
JP2613000B2 (ja) 1992-11-30 1997-05-21 大倉工業株式会社 パーテイクルボードの製造方法
JP3168550B2 (ja) * 1992-12-02 2001-05-21 株式会社林原生物化学研究所 脱水剤およびそれを用いる含水物の脱水方法並びにその方法で得られる脱水物品
EP0606753B1 (de) * 1992-12-28 1999-07-21 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo Nichtreduzierendes saccharidbildendes Enzym, und dessen Herstellung und Verwendungen
JP3559585B2 (ja) * 1993-06-03 2004-09-02 株式会社林原生物化学研究所 トレハロース遊離酵素とその製造方法並びに用途
JP3557277B2 (ja) * 1994-06-25 2004-08-25 株式会社林原生物化学研究所 耐熱性トレハロース遊離酵素とその製造方法並びに用途

Also Published As

Publication number Publication date
EP0688866B1 (de) 1998-09-09
JPH0866187A (ja) 1996-03-12
US5723327A (en) 1998-03-03
KR100391376B1 (ko) 2003-10-22
DE69504584D1 (de) 1998-10-15
CA2151438C (en) 2007-02-20
DK0688866T3 (da) 1999-06-07
AU694213B2 (en) 1998-07-16
AU2323995A (en) 1996-01-11
KR960001112A (ko) 1996-01-25
JP3557277B2 (ja) 2004-08-25
EP0688866A1 (de) 1995-12-27
CA2151438A1 (en) 1995-12-26
ATE170920T1 (de) 1998-09-15
US6150153A (en) 2000-11-21
TW507008B (en) 2002-10-21

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