DE69506426D1 - Vorrichtung zur iontophorestischen verabreichung versehen mit verbesserter sicherheit und vermeidung von missbräuchlichem potential - Google Patents

Vorrichtung zur iontophorestischen verabreichung versehen mit verbesserter sicherheit und vermeidung von missbräuchlichem potential

Info

Publication number
DE69506426D1
DE69506426D1 DE69506426T DE69506426T DE69506426D1 DE 69506426 D1 DE69506426 D1 DE 69506426D1 DE 69506426 T DE69506426 T DE 69506426T DE 69506426 T DE69506426 T DE 69506426T DE 69506426 D1 DE69506426 D1 DE 69506426D1
Authority
DE
Germany
Prior art keywords
disabling
permanent
current
electrodes
permanently
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69506426T
Other languages
English (en)
Other versions
DE69506426T2 (de
Inventor
Larry Mcnichols
John Badzinski
William Reining
Gary Lattin
Ronald Haak
Joseph Phipps
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alza Corp
Original Assignee
Alza Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alza Corp filed Critical Alza Corp
Publication of DE69506426D1 publication Critical patent/DE69506426D1/de
Application granted granted Critical
Publication of DE69506426T2 publication Critical patent/DE69506426T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A61N1/0432—Anode and cathode
    • A61N1/0436—Material of the electrode
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/20—Applying electric currents by contact electrodes continuous direct currents
    • A61N1/30—Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/325—Applying electric currents by contact electrodes alternating or intermittent currents for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0412—Specially adapted for transcutaneous electroporation, e.g. including drug reservoirs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A61N1/0448—Drug reservoir
DE69506426T 1994-09-26 1995-09-21 Vorrichtung zur iontophorestischen verabreichung versehen mit verbesserter sicherheit und vermeidung von missbräuchlichem potential Expired - Lifetime DE69506426T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/312,336 US7027859B1 (en) 1994-09-26 1994-09-26 Electrotransport delivery device having improved safety and reduced abuse potential
PCT/US1995/012003 WO1996009850A2 (en) 1994-09-26 1995-09-21 Electrotransport delivery device having improved safety and reduced abuse potential

Publications (2)

Publication Number Publication Date
DE69506426D1 true DE69506426D1 (de) 1999-01-14
DE69506426T2 DE69506426T2 (de) 1999-05-27

Family

ID=23210983

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69506426T Expired - Lifetime DE69506426T2 (de) 1994-09-26 1995-09-21 Vorrichtung zur iontophorestischen verabreichung versehen mit verbesserter sicherheit und vermeidung von missbräuchlichem potential

Country Status (11)

Country Link
US (3) US7027859B1 (de)
EP (1) EP0781152B1 (de)
JP (2) JP4165659B2 (de)
KR (1) KR100372205B1 (de)
AT (1) ATE173942T1 (de)
AU (1) AU3594095A (de)
CA (1) CA2195657C (de)
DE (1) DE69506426T2 (de)
DK (1) DK0781152T3 (de)
ES (1) ES2125660T3 (de)
WO (1) WO1996009850A2 (de)

Families Citing this family (66)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996010440A1 (en) * 1994-09-30 1996-04-11 Becton Dickinson And Company Iontophoretic drug delivery device having improved controller and patch
US6881208B1 (en) * 1995-06-05 2005-04-19 Joseph B. Phipps Method and device for transdermal electrotransport delivery of fentanyl and sufentanil
US6208891B1 (en) * 1997-04-04 2001-03-27 Drug Delivery Technologies, Inc. Disabling circuit for an iontophoretic system
US6029083A (en) * 1997-04-04 2000-02-22 Becton, Dickinson And Company Circuit and method for automatically turning off an iontophoresis system
IL123290A (en) * 1998-02-13 2001-12-23 Hadasit Med Res Service Iontophoretic device
US6385488B1 (en) * 1999-05-20 2002-05-07 Vyteris, Inc. Circuits for increasing the reliability of an iontophoretic system
AU2000275456A1 (en) * 2000-10-05 2002-04-15 Spes Patents Limited Apparatus for applying electronic treatment
DE10141650C1 (de) 2001-08-24 2002-11-28 Lohmann Therapie Syst Lts Transdermales Therapeutisches System mit Fentanyl bzw. verwandten Substanzen
US7142909B2 (en) * 2002-04-11 2006-11-28 Second Sight Medical Products, Inc. Biocompatible bonding method and electronics package suitable for implantation
US7031769B2 (en) * 2003-02-21 2006-04-18 Birch Point Medical, Inc. Dosage control electrode for iontophoresis device
ATE478061T1 (de) * 2004-01-30 2010-09-15 Schering Corp Kristalline polymorphe eines cxc- chemokinrezeptorliganden
EP1960035A4 (de) * 2005-11-30 2010-01-06 Xavant Technology Pty Ltd Medizinische vorrichtung
US20080009782A1 (en) * 2006-06-28 2008-01-10 Alza Corporation Methods and Devices for Transdermal Electrotransport Delivery of Lofentanil and Carfentanil
US9119582B2 (en) 2006-06-30 2015-09-01 Abbott Diabetes Care, Inc. Integrated analyte sensor and infusion device and methods therefor
EP2043733A1 (de) * 2007-06-26 2009-04-08 Alza Corporation Verfahren und vorrichtungen zur transdermalen elektrotransport-verabreichung von lofentanil und carfentanil
US7967795B1 (en) 2010-01-19 2011-06-28 Lamodel Ltd. Cartridge interface assembly with driving plunger
US9345836B2 (en) 2007-10-02 2016-05-24 Medimop Medical Projects Ltd. Disengagement resistant telescoping assembly and unidirectional method of assembly for such
WO2009044401A2 (en) 2007-10-02 2009-04-09 Yossi Gross External drug pump
US9656019B2 (en) 2007-10-02 2017-05-23 Medimop Medical Projects Ltd. Apparatuses for securing components of a drug delivery system during transport and methods of using same
US10420880B2 (en) 2007-10-02 2019-09-24 West Pharma. Services IL, Ltd. Key for securing components of a drug delivery system during assembly and/or transport and methods of using same
US9393369B2 (en) 2008-09-15 2016-07-19 Medimop Medical Projects Ltd. Stabilized pen injector
US10071198B2 (en) 2012-11-02 2018-09-11 West Pharma. Servicees IL, Ltd. Adhesive structure for medical device
US10071196B2 (en) 2012-05-15 2018-09-11 West Pharma. Services IL, Ltd. Method for selectively powering a battery-operated drug-delivery device and device therefor
US8157769B2 (en) 2009-09-15 2012-04-17 Medimop Medical Projects Ltd. Cartridge insertion assembly for drug delivery system
US8348898B2 (en) 2010-01-19 2013-01-08 Medimop Medical Projects Ltd. Automatic needle for drug pump
WO2011141907A1 (en) 2010-05-10 2011-11-17 Medimop Medical Projects Ltd. Low volume accurate injector
US9881521B2 (en) * 2011-01-17 2018-01-30 Prestan Products Llc Manikin sensing pads and liners in an AED training system
DE102011011910A1 (de) * 2011-02-21 2012-08-23 Giesecke & Devrient Gmbh Inbetriebnahme eines portablen Datenträgers
USD702834S1 (en) 2011-03-22 2014-04-15 Medimop Medical Projects Ltd. Cartridge for use in injection device
US8428709B1 (en) * 2012-06-11 2013-04-23 Incline Therapeutics, Inc. Current control for electrotransport drug delivery
US8781571B2 (en) 2011-03-31 2014-07-15 Incline Therapeutics, Inc. Switch validation circuit and method
US8428708B1 (en) 2012-05-21 2013-04-23 Incline Therapeutics, Inc. Self-test for analgesic product
US9731121B2 (en) 2011-03-31 2017-08-15 Incline Therapeutics, Inc. Switch validation circuit and method
US8301238B2 (en) 2011-03-31 2012-10-30 Incline Therapeutics, Inc. Two-part electrotransport device
EP2809375B1 (de) 2012-01-31 2021-08-11 Medimop Medical Projects Ltd. Zeitabhängige wirkstofffreisetzungsvorrichtung
US9463280B2 (en) 2012-03-26 2016-10-11 Medimop Medical Projects Ltd. Motion activated septum puncturing drug delivery device
US10668213B2 (en) 2012-03-26 2020-06-02 West Pharma. Services IL, Ltd. Motion activated mechanisms for a drug delivery device
US9072827B2 (en) 2012-03-26 2015-07-07 Medimop Medical Projects Ltd. Fail safe point protector for needle safety flap
US9421323B2 (en) 2013-01-03 2016-08-23 Medimop Medical Projects Ltd. Door and doorstop for portable one use drug delivery apparatus
US9011164B2 (en) 2013-04-30 2015-04-21 Medimop Medical Projects Ltd. Clip contact for easy installation of printed circuit board PCB
US9889256B2 (en) 2013-05-03 2018-02-13 Medimop Medical Projects Ltd. Sensing a status of an infuser based on sensing motor control and power input
FR3015299B1 (fr) * 2013-12-20 2017-10-06 Oreal Dispositif d'iontophorese a gestion independante de courant
FR3015300B1 (fr) * 2013-12-20 2018-03-02 L'oreal Dispositif d'iontophorese a reservoir
WO2016065190A1 (en) 2014-10-23 2016-04-28 Abbott Diabetes Care Inc. Electrodes having at least one sensing structure and methods for making and using the same
US10251813B2 (en) 2015-03-04 2019-04-09 West Pharma. Services IL, Ltd. Flexibly mounted cartridge alignment collar for drug delivery device
US9795534B2 (en) 2015-03-04 2017-10-24 Medimop Medical Projects Ltd. Compliant coupling assembly for cartridge coupling of a drug delivery device
US10293120B2 (en) 2015-04-10 2019-05-21 West Pharma. Services IL, Ltd. Redundant injection device status indication
US9744297B2 (en) 2015-04-10 2017-08-29 Medimop Medical Projects Ltd. Needle cannula position as an input to operational control of an injection device
AU2016202751B2 (en) * 2015-04-30 2019-11-07 Richard Malter Iontophoresis device and method of treatment
US10149943B2 (en) 2015-05-29 2018-12-11 West Pharma. Services IL, Ltd. Linear rotation stabilizer for a telescoping syringe stopper driverdriving assembly
EP4252798A3 (de) 2015-06-04 2023-10-25 Medimop Medical Projects Ltd. Kartuscheneinführung für arzneimittelabgavevorrichtung
KR101628299B1 (ko) * 2015-09-09 2016-06-08 (주)와이브레인 전극 패드
US10576207B2 (en) 2015-10-09 2020-03-03 West Pharma. Services IL, Ltd. Angled syringe patch injector
US9987432B2 (en) 2015-09-22 2018-06-05 West Pharma. Services IL, Ltd. Rotation resistant friction adapter for plunger driver of drug delivery device
CN113648488B (zh) 2015-10-09 2024-03-29 西医药服务以色列分公司 至预填充的流体储存器的弯曲流体路径附加装置
MX2018008093A (es) * 2016-01-08 2018-08-23 Philip Morris Products Sa Un componente para un sistema generador de aerosol que comprende un medio de inhabilitacion.
WO2017127215A1 (en) 2016-01-21 2017-07-27 Medimop Medical Projects Ltd. Needle insertion and retraction mechanism
EP3405227B1 (de) 2016-01-21 2020-06-17 West Pharma. Services Il, Ltd. Krafteindämmung in einem automatischen injektor
CN113041432B (zh) 2016-01-21 2023-04-07 西医药服务以色列有限公司 包括视觉指示物的药剂输送装置
US11389597B2 (en) 2016-03-16 2022-07-19 West Pharma. Services IL, Ltd. Staged telescopic screw assembly having different visual indicators
US11103652B2 (en) 2016-06-02 2021-08-31 West Pharma. Services IL, Ltd. Three position needle retraction
WO2018026385A1 (en) 2016-08-01 2018-02-08 Medimop Medical Projects Ltd. Partial door closure prevention spring
CN109562229B (zh) 2016-08-01 2021-07-13 西医药服务以色列有限公司 抗旋转药筒销
EP3630226A1 (de) 2017-05-30 2020-04-08 West Pharma. Services Il, Ltd. Modularer antriebsstrang für am körper tragbaren injektor
CN114470420A (zh) 2017-12-22 2022-05-13 西氏医药包装(以色列)有限公司 适用于不同尺寸的药筒的注射器
US11139256B2 (en) * 2019-08-21 2021-10-05 Micron Technology, Inc. Tamper-resistant integrated circuits, and related methods

Family Cites Families (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3493657A (en) 1961-03-14 1970-02-03 Mozes Juda Lewenstein Therapeutic compositions of n-allyl-14-hydroxy - dihydronormorphinane and morphine
US3773955A (en) 1970-08-03 1973-11-20 Bristol Myers Co Analgetic compositions
US4141359A (en) 1976-08-16 1979-02-27 University Of Utah Epidermal iontophoresis device
JPS54109279A (en) * 1978-02-15 1979-08-27 Masao Oku Electric medicine injector
US4457933A (en) 1980-01-24 1984-07-03 Bristol-Myers Company Prevention of analgesic abuse
JPS5810066A (ja) 1981-07-10 1983-01-20 株式会社アドバンス イオントフオレ−ゼ用プラスタ−構造体
JPS58183044A (ja) 1982-04-21 1983-10-26 Q P Corp 高速割卵機における殻付卵の受渡し方法およびその装置
US5167617A (en) 1983-08-18 1992-12-01 Drug Delivery Systems Inc. Disposable electralytic transdermal drug applicator
US4731926A (en) 1985-02-19 1988-03-22 Drug Delivery Systems Inc. Method of manufacturing disposable and/or replenishable transdermal drug applicators
US5135479A (en) 1983-08-18 1992-08-04 Drug Delivery Systems, Inc. Programmable control and mounting system for transdermal drug applicator
US5224928A (en) 1983-08-18 1993-07-06 Drug Delivery Systems Inc. Mounting system for transdermal drug applicator
US4588580B2 (en) 1984-07-23 1999-02-16 Alaz Corp Transdermal administration of fentanyl and device therefor
US5135477A (en) 1984-10-29 1992-08-04 Medtronic, Inc. Iontophoretic drug delivery
EP0461680A3 (en) * 1985-06-10 1992-02-26 Drug Delivery Systems Inc. Programmable control and mounting system for transdermal drug applicator
JPH0657259B2 (ja) 1986-04-21 1994-08-03 松下電工株式会社 低周波美容器
US4822334A (en) * 1986-12-04 1989-04-18 Robert Tapper Electrical dosimetry control system
US4942883A (en) 1987-09-29 1990-07-24 Newman Martin H Drug delivery device
US5169382A (en) 1988-10-03 1992-12-08 Alza Corporation Membrane for electrotransport transdermal drug delivery
US5006108A (en) 1988-11-16 1991-04-09 Noven Pharmaceuticals, Inc. Apparatus for iontophoretic drug delivery
JP2822215B2 (ja) * 1989-07-17 1998-11-11 林原 健 頭皮を通電刺激するための装置
JPH03173317A (ja) 1989-11-30 1991-07-26 Nippondenso Co Ltd 太陽光利用電源装置
IT1244030B (it) 1989-12-21 1994-06-28 Elan Corp Plc Dispostitivo in due parti per la somministrazione controllata di un ingrediente
US5047007A (en) 1989-12-22 1991-09-10 Medtronic, Inc. Method and apparatus for pulsed iontophoretic drug delivery
US5207752A (en) 1990-03-30 1993-05-04 Alza Corporation Iontophoretic drug delivery system with two-stage delivery profile
US5213568A (en) * 1990-03-30 1993-05-25 Medtronic Inc. Activity controlled electrotransport drug delivery device
JP2801083B2 (ja) * 1990-04-30 1998-09-21 アルザ・コーポレーション イオン導入による薬物投与デバイスと方法
US5147297A (en) 1990-05-07 1992-09-15 Alza Corporation Iontophoretic delivery device
US5037381A (en) 1990-07-27 1991-08-06 Bock C Randolph Electrically assisted transdermal transport device and method for renewing the device
US5160316A (en) * 1990-09-10 1992-11-03 Henley Julian L Iontophoretic drug delivery apparatus
US5224927A (en) 1990-11-01 1993-07-06 Robert Tapper Iontophoretic treatment system
US5254081A (en) 1991-02-01 1993-10-19 Empi, Inc. Multiple site drug iontophoresis electronic device and method
US5203768A (en) 1991-07-24 1993-04-20 Alza Corporation Transdermal delivery device
US5246417A (en) * 1991-12-11 1993-09-21 Alza Corporation Indicator for iontophoresis system
US5246418A (en) 1991-12-17 1993-09-21 Becton Dickinson And Company Iontophresis system having features for reducing skin irritation
FR2687321B1 (fr) * 1992-02-14 1999-04-16 Elf Aquitaine Dispositif d'ionophorese pour l'administration transcutanee d'une quantite totale donnee d'un principe actif a un sujet.
JPH0623060A (ja) * 1992-07-07 1994-02-01 Citizen Watch Co Ltd 電子薬物投与器
US5306235A (en) 1992-09-30 1994-04-26 Becton Dickinson And Company Failsafe iontophoresis drug delivery system

Also Published As

Publication number Publication date
EP0781152A2 (de) 1997-07-02
KR100372205B1 (ko) 2003-04-10
US20060116662A1 (en) 2006-06-01
JP4165659B2 (ja) 2008-10-15
CA2195657A1 (en) 1996-04-04
US7027859B1 (en) 2006-04-11
US20100076368A1 (en) 2010-03-25
KR970706037A (ko) 1997-11-03
ATE173942T1 (de) 1998-12-15
AU3594095A (en) 1996-04-19
ES2125660T3 (es) 1999-03-01
US7660627B2 (en) 2010-02-09
EP0781152B1 (de) 1998-12-02
DE69506426T2 (de) 1999-05-27
JPH10506553A (ja) 1998-06-30
CA2195657C (en) 2009-12-22
JP4322304B2 (ja) 2009-08-26
WO1996009850A2 (en) 1996-04-04
WO1996009850A3 (en) 1996-05-30
DK0781152T3 (da) 1999-08-16
JP2008220985A (ja) 2008-09-25

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