DE69508791D1 - Intravaginale vorrichtung zur verabreichung von 17beta-oestradiol vorläufer - Google Patents
Intravaginale vorrichtung zur verabreichung von 17beta-oestradiol vorläuferInfo
- Publication number
- DE69508791D1 DE69508791D1 DE69508791T DE69508791T DE69508791D1 DE 69508791 D1 DE69508791 D1 DE 69508791D1 DE 69508791 T DE69508791 T DE 69508791T DE 69508791 T DE69508791 T DE 69508791T DE 69508791 D1 DE69508791 D1 DE 69508791D1
- Authority
- DE
- Germany
- Prior art keywords
- 17beta
- administrating
- intravaginal device
- oestradiol precursors
- oestradiol
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- VOXZDWNPVJITMN-ZBRFXRBCSA-N 17β-estradiol Chemical compound OC1=CC=C2[C@H]3CC[C@](C)([C@H](CC4)O)[C@@H]4[C@@H]3CCC2=C1 VOXZDWNPVJITMN-ZBRFXRBCSA-N 0.000 title 2
- 229960005309 estradiol Drugs 0.000 title 1
- 239000002243 precursor Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
- A61K9/0036—Devices retained in the vagina or cervix for a prolonged period, e.g. intravaginal rings, medicated tampons, medicated diaphragms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/18—Feminine contraceptives
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IES940976 | 1994-12-19 | ||
IES950247 | 1995-04-05 | ||
PCT/IE1995/000063 WO1996019196A1 (en) | 1994-12-19 | 1995-12-19 | INTRAVAGINAL DRUG DELIVERY DEVICES FOR THE ADMINISTRATION OF 17β-OESTRADIOL PRECURSORS |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69508791D1 true DE69508791D1 (de) | 1999-05-06 |
DE69508791T2 DE69508791T2 (de) | 1999-12-02 |
Family
ID=26319777
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69508791T Expired - Lifetime DE69508791T2 (de) | 1994-12-19 | 1995-12-19 | Intravaginale vorrichtung zur verabreichung von 17beta-oestradiol vorläufer |
Country Status (19)
Country | Link |
---|---|
US (1) | US5855906A (de) |
EP (1) | EP0799025B1 (de) |
JP (1) | JPH10510825A (de) |
CN (1) | CN1138526C (de) |
AR (1) | AR002010A1 (de) |
AT (1) | ATE178204T1 (de) |
AU (1) | AU692659B2 (de) |
CA (1) | CA2207622C (de) |
DE (1) | DE69508791T2 (de) |
DK (1) | DK0799025T3 (de) |
ES (1) | ES2133841T3 (de) |
FI (1) | FI119414B (de) |
GR (1) | GR3030614T3 (de) |
IL (1) | IL116433A (de) |
NO (1) | NO316707B1 (de) |
NZ (1) | NZ298490A (de) |
PE (1) | PE62796A1 (de) |
TR (1) | TR199501599A2 (de) |
WO (1) | WO1996019196A1 (de) |
Families Citing this family (45)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6407082B1 (en) * | 1996-09-13 | 2002-06-18 | New Life Pharmaceuticals Inc. | Prevention of ovarian cancer by administration of a vitamin D compound |
US6028064A (en) | 1996-09-13 | 2000-02-22 | New Life Pharmaceuticals Inc. | Prevention of ovarian cancer by administration of progestin products |
US6511970B1 (en) | 1996-09-13 | 2003-01-28 | New Life Pharmaceuticals Inc. | Prevention of ovarian cancer by administration of products that induce transforming growth factor-beta and/or apoptosis in the ovarian epithelium |
US6765002B2 (en) | 2000-03-21 | 2004-07-20 | Gustavo Rodriguez | Prevention of ovarian cancer by administration of products that induce transforming growth factor-β and/or apoptosis in the ovarian epithelium |
US6034074A (en) | 1996-09-13 | 2000-03-07 | New Life Pharmaceuticals Inc. | Prevention of ovarian cancer by administration of a Vitamin D compound |
ATE227120T1 (de) * | 1997-05-07 | 2002-11-15 | Galen Chemicals Ltd | Vorrichtungen zur intravaginalen verabreichung von testosteron und testosteron- vorläuferverbindungen |
US6039968A (en) * | 1997-06-24 | 2000-03-21 | Hoechst Marion Roussel | Intravaginal drug delivery device |
US20040176336A1 (en) * | 2000-03-21 | 2004-09-09 | Rodriguez Gustavo C. | Prevention of ovarian cancer by administration of products that induce biologic effects in the ovarian epithelium |
US20010044431A1 (en) * | 2000-03-21 | 2001-11-22 | Rodriguez Gustavo C. | Prevention of ovarian cancer by administration of products that induce biologic effects in the ovarian epithelium |
US20050113351A1 (en) * | 2000-03-21 | 2005-05-26 | Rodriguez Gustavo C. | Prevention of ovarian cancer by administration of products that induce biologic effects in the ovarian epithelium |
US6811549B2 (en) * | 2001-02-16 | 2004-11-02 | William H. Fleming | Administration of therapeutic or diagnostic agents using interlabial pad |
US6962908B2 (en) * | 2001-12-21 | 2005-11-08 | Warner Chilcott Company Inc. | Oral pharmaceutical products containing 17 β-estradiol-3-lower alkanoate, method of administering the same and process of preparation |
US9993424B2 (en) * | 2002-03-27 | 2018-06-12 | Allergan Pharmaceuticals International Limited | Intravaginal matrix drug delivery devices |
GB0222522D0 (en) | 2002-09-27 | 2002-11-06 | Controlled Therapeutics Sct | Water-swellable polymers |
US7833545B2 (en) * | 2003-04-29 | 2010-11-16 | The General Hospital Corporation | Methods and devices for the sustained release of multiple drugs |
GB0417401D0 (en) | 2004-08-05 | 2004-09-08 | Controlled Therapeutics Sct | Stabilised prostaglandin composition |
WO2006084082A1 (en) * | 2005-02-03 | 2006-08-10 | Duramed Pharmaceuticals, Inc. | Compositions of unconjugated estrogens and methods for their use |
WO2006084083A2 (en) * | 2005-02-03 | 2006-08-10 | Duramed Pharmaceuticals, Inc. | Devices for delivering agents to a vaginal tract |
US8801694B2 (en) * | 2005-08-11 | 2014-08-12 | Massachusetts Institute Of Technology | Intravesical drug delivery device |
US20070077269A1 (en) * | 2005-10-04 | 2007-04-05 | Woodward John R | Method of birth control and hormone regulation |
CN103251449B (zh) * | 2005-10-13 | 2016-03-02 | 斯恩蒂斯有限公司 | 载药包装物 |
GB0613333D0 (en) * | 2006-07-05 | 2006-08-16 | Controlled Therapeutics Sct | Hydrophilic polyurethane compositions |
GB0613638D0 (en) | 2006-07-08 | 2006-08-16 | Controlled Therapeutics Sct | Polyurethane elastomers |
US20080160065A1 (en) * | 2006-07-12 | 2008-07-03 | Janet Anne Halliday | Drug delivery polymer with hydrochloride salt of clindamycin |
GB0620685D0 (en) * | 2006-10-18 | 2006-11-29 | Controlled Therapeutics Sct | Bioresorbable polymers |
ES2696999T3 (es) | 2007-06-26 | 2019-01-21 | Allergan Pharmaceuticals Int Ltd | Dispositivos de administración intravaginal de medicamentos para la administración de macromoléculas y medicamentos solubles en agua |
JP5560200B2 (ja) | 2007-12-11 | 2014-07-23 | マサチューセッツ インスチテュート オブ テクノロジー | 膀胱および他の身体の小嚢又は管腔を治療するための埋め込み型薬物供給デバイス |
BRPI0917135A2 (pt) * | 2008-08-09 | 2015-11-10 | Massachusetts Inst Technology | dispositivo médico para extensão e retenção em uma vesícula seminal, duto ejaculatório, próstata ou vaso deferente de um paciente, uso de um elastômero reabsorvível, e, dispositivo de bomba osmótica. |
JP5695035B2 (ja) | 2009-06-03 | 2015-04-01 | フォーサイト・ビジョン5・インコーポレイテッドForsight Vision5,Inc. | 前眼部薬物供給 |
EA023156B1 (ru) | 2009-06-26 | 2016-04-29 | ТАРИС Биомедикал ЛЛК | Устройство для доставки лекарств |
US9017312B2 (en) | 2009-09-10 | 2015-04-28 | Taris Biomedical Llc | Implantable device for controlled drug delivery |
US8580294B2 (en) | 2010-10-19 | 2013-11-12 | International Partnership For Microbicides | Platinum-catalyzed intravaginal rings |
EP2663300B1 (de) | 2011-01-10 | 2023-03-08 | TARIS Biomedical LLC | Lidocain dosierungsschema zur verwendung bei einer anhaltenden behandlung von blasenschmerzen und schmerzhaftem harnabgang |
WO2012106714A1 (en) | 2011-02-04 | 2012-08-09 | Taris Biomedical, Inc. | Implantable device for controlled release of low solubility drug |
WO2013040426A2 (en) | 2011-09-14 | 2013-03-21 | Forsight Labs, Llc | Ocular insert apparatus and methods |
TWI590843B (zh) | 2011-12-28 | 2017-07-11 | 信迪思有限公司 | 膜及其製造方法 |
WO2014066775A1 (en) | 2012-10-26 | 2014-05-01 | Forsight Vision5, Inc. | Ophthalmic system for sustained release of drug to eye |
CN105163794B (zh) | 2013-03-15 | 2020-03-27 | 塔里斯生物医药公司 | 具有药物可渗透部件的药物递送装置和方法 |
EP3010560B1 (de) | 2013-06-21 | 2020-01-01 | DePuy Synthes Products, Inc. | Folien und verfahren zur herstellung |
EP4234036A3 (de) | 2013-08-19 | 2023-11-01 | TARIS Biomedical LLC | Vorrichtungen zur abgabe mehrteiliger wirkstoffe |
CN104546668B (zh) * | 2013-10-23 | 2019-03-05 | 国家卫生计生委科学技术研究所 | 液体硅橡胶为载体的药物缓控释系统的制备及应用 |
US10137031B2 (en) | 2013-11-14 | 2018-11-27 | International Partnership For Microbicides, Inc. | Combination therapy intravaginal rings |
EP3125964A4 (de) * | 2014-04-01 | 2018-02-28 | Poly-Med Inc. | Verhütungsmittel und zugehörige vorrichtung |
US20160296532A1 (en) | 2015-04-13 | 2016-10-13 | Forsight Vision5, Inc. | Ocular Insert Composition of a Semi-Crystalline or Crystalline Pharmaceutically Active Agent |
EP3285850A1 (de) | 2015-04-23 | 2018-02-28 | TARIS Biomedical LLC | Wirkstoffabgabevorrichtungen mit einer wirkstoffdurchlässigen komponente und verfahren |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3545439A (en) * | 1968-01-04 | 1970-12-08 | Upjohn Co | Medicated devices and methods |
US4291014A (en) * | 1979-01-11 | 1981-09-22 | Key Pharmaceuticals, Inc. | Polymeric diffusion matrix containing estradiol diacetate |
US4438139A (en) * | 1979-08-14 | 1984-03-20 | Key Pharmaceuticals, Inc. | Polymeric diffusion matrix containing estrogens |
SE8602666D0 (sv) * | 1986-06-16 | 1986-06-16 | Leo Ab | Intravaginal devices |
-
1995
- 1995-12-18 IL IL11643395A patent/IL116433A/en not_active IP Right Cessation
- 1995-12-19 US US08/849,329 patent/US5855906A/en not_active Expired - Lifetime
- 1995-12-19 AU AU43991/96A patent/AU692659B2/en not_active Ceased
- 1995-12-19 TR TR95/01599A patent/TR199501599A2/xx unknown
- 1995-12-19 EP EP95942772A patent/EP0799025B1/de not_active Expired - Lifetime
- 1995-12-19 DE DE69508791T patent/DE69508791T2/de not_active Expired - Lifetime
- 1995-12-19 ES ES95942772T patent/ES2133841T3/es not_active Expired - Lifetime
- 1995-12-19 WO PCT/IE1995/000063 patent/WO1996019196A1/en active IP Right Grant
- 1995-12-19 PE PE1995287516A patent/PE62796A1/es not_active Application Discontinuation
- 1995-12-19 CN CNB951968947A patent/CN1138526C/zh not_active Expired - Lifetime
- 1995-12-19 AT AT95942772T patent/ATE178204T1/de not_active IP Right Cessation
- 1995-12-19 JP JP8519650A patent/JPH10510825A/ja not_active Ceased
- 1995-12-19 NZ NZ298490A patent/NZ298490A/xx unknown
- 1995-12-19 AR ARP950100619A patent/AR002010A1/es unknown
- 1995-12-19 CA CA002207622A patent/CA2207622C/en not_active Expired - Lifetime
- 1995-12-19 DK DK95942772T patent/DK0799025T3/da active
-
1997
- 1997-06-17 NO NO19972798A patent/NO316707B1/no unknown
- 1997-06-17 FI FI972579A patent/FI119414B/fi not_active IP Right Cessation
-
1999
- 1999-06-29 GR GR990401699T patent/GR3030614T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
DE69508791T2 (de) | 1999-12-02 |
ES2133841T3 (es) | 1999-09-16 |
AR002010A1 (es) | 1998-01-07 |
NZ298490A (en) | 1999-11-29 |
PE62796A1 (es) | 1996-12-28 |
JPH10510825A (ja) | 1998-10-20 |
FI119414B (fi) | 2008-11-14 |
NO316707B1 (no) | 2004-04-13 |
NO972798L (no) | 1997-08-19 |
WO1996019196A1 (en) | 1996-06-27 |
DK0799025T3 (da) | 1999-10-18 |
GR3030614T3 (en) | 1999-10-29 |
FI972579A0 (fi) | 1997-06-17 |
EP0799025B1 (de) | 1999-03-31 |
FI972579A (fi) | 1997-06-17 |
ATE178204T1 (de) | 1999-04-15 |
AU692659B2 (en) | 1998-06-11 |
CA2207622C (en) | 2006-10-17 |
US5855906A (en) | 1999-01-05 |
CN1138526C (zh) | 2004-02-18 |
EP0799025A1 (de) | 1997-10-08 |
IL116433A (en) | 2002-02-10 |
IL116433A0 (en) | 1996-03-31 |
CA2207622A1 (en) | 1996-06-27 |
AU4399196A (en) | 1996-07-10 |
TR199501599A2 (tr) | 1996-07-21 |
NO972798D0 (no) | 1997-06-17 |
CN1170353A (zh) | 1998-01-14 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8328 | Change in the person/name/address of the agent |
Representative=s name: HANSMANN & VOGESER, 81369 MUENCHEN |
|
R082 | Change of representative |
Ref document number: 799025 Country of ref document: EP Representative=s name: PATENT- UND RECHTSANWAELTE HANSMANN & VOGESER, 823 |