DE69508791D1 - Intravaginale vorrichtung zur verabreichung von 17beta-oestradiol vorläufer - Google Patents

Intravaginale vorrichtung zur verabreichung von 17beta-oestradiol vorläufer

Info

Publication number
DE69508791D1
DE69508791D1 DE69508791T DE69508791T DE69508791D1 DE 69508791 D1 DE69508791 D1 DE 69508791D1 DE 69508791 T DE69508791 T DE 69508791T DE 69508791 T DE69508791 T DE 69508791T DE 69508791 D1 DE69508791 D1 DE 69508791D1
Authority
DE
Germany
Prior art keywords
17beta
administrating
intravaginal device
oestradiol precursors
oestradiol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69508791T
Other languages
English (en)
Other versions
DE69508791T2 (de
Inventor
Allen Mcclay
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Warner Chilcott Ireland Ltd
Original Assignee
Galen Chemicals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Galen Chemicals Ltd filed Critical Galen Chemicals Ltd
Application granted granted Critical
Publication of DE69508791D1 publication Critical patent/DE69508791D1/de
Publication of DE69508791T2 publication Critical patent/DE69508791T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0034Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A61K9/0036Devices retained in the vagina or cervix for a prolonged period, e.g. intravaginal rings, medicated tampons, medicated diaphragms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18Feminine contraceptives
DE69508791T 1994-12-19 1995-12-19 Intravaginale vorrichtung zur verabreichung von 17beta-oestradiol vorläufer Expired - Lifetime DE69508791T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IES940976 1994-12-19
IES950247 1995-04-05
PCT/IE1995/000063 WO1996019196A1 (en) 1994-12-19 1995-12-19 INTRAVAGINAL DRUG DELIVERY DEVICES FOR THE ADMINISTRATION OF 17β-OESTRADIOL PRECURSORS

Publications (2)

Publication Number Publication Date
DE69508791D1 true DE69508791D1 (de) 1999-05-06
DE69508791T2 DE69508791T2 (de) 1999-12-02

Family

ID=26319777

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69508791T Expired - Lifetime DE69508791T2 (de) 1994-12-19 1995-12-19 Intravaginale vorrichtung zur verabreichung von 17beta-oestradiol vorläufer

Country Status (19)

Country Link
US (1) US5855906A (de)
EP (1) EP0799025B1 (de)
JP (1) JPH10510825A (de)
CN (1) CN1138526C (de)
AR (1) AR002010A1 (de)
AT (1) ATE178204T1 (de)
AU (1) AU692659B2 (de)
CA (1) CA2207622C (de)
DE (1) DE69508791T2 (de)
DK (1) DK0799025T3 (de)
ES (1) ES2133841T3 (de)
FI (1) FI119414B (de)
GR (1) GR3030614T3 (de)
IL (1) IL116433A (de)
NO (1) NO316707B1 (de)
NZ (1) NZ298490A (de)
PE (1) PE62796A1 (de)
TR (1) TR199501599A2 (de)
WO (1) WO1996019196A1 (de)

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US6407082B1 (en) * 1996-09-13 2002-06-18 New Life Pharmaceuticals Inc. Prevention of ovarian cancer by administration of a vitamin D compound
US6028064A (en) 1996-09-13 2000-02-22 New Life Pharmaceuticals Inc. Prevention of ovarian cancer by administration of progestin products
US6511970B1 (en) 1996-09-13 2003-01-28 New Life Pharmaceuticals Inc. Prevention of ovarian cancer by administration of products that induce transforming growth factor-beta and/or apoptosis in the ovarian epithelium
US6765002B2 (en) 2000-03-21 2004-07-20 Gustavo Rodriguez Prevention of ovarian cancer by administration of products that induce transforming growth factor-β and/or apoptosis in the ovarian epithelium
US6034074A (en) 1996-09-13 2000-03-07 New Life Pharmaceuticals Inc. Prevention of ovarian cancer by administration of a Vitamin D compound
ATE227120T1 (de) * 1997-05-07 2002-11-15 Galen Chemicals Ltd Vorrichtungen zur intravaginalen verabreichung von testosteron und testosteron- vorläuferverbindungen
US6039968A (en) * 1997-06-24 2000-03-21 Hoechst Marion Roussel Intravaginal drug delivery device
US20040176336A1 (en) * 2000-03-21 2004-09-09 Rodriguez Gustavo C. Prevention of ovarian cancer by administration of products that induce biologic effects in the ovarian epithelium
US20010044431A1 (en) * 2000-03-21 2001-11-22 Rodriguez Gustavo C. Prevention of ovarian cancer by administration of products that induce biologic effects in the ovarian epithelium
US20050113351A1 (en) * 2000-03-21 2005-05-26 Rodriguez Gustavo C. Prevention of ovarian cancer by administration of products that induce biologic effects in the ovarian epithelium
US6811549B2 (en) * 2001-02-16 2004-11-02 William H. Fleming Administration of therapeutic or diagnostic agents using interlabial pad
US6962908B2 (en) * 2001-12-21 2005-11-08 Warner Chilcott Company Inc. Oral pharmaceutical products containing 17 β-estradiol-3-lower alkanoate, method of administering the same and process of preparation
US9993424B2 (en) * 2002-03-27 2018-06-12 Allergan Pharmaceuticals International Limited Intravaginal matrix drug delivery devices
GB0222522D0 (en) 2002-09-27 2002-11-06 Controlled Therapeutics Sct Water-swellable polymers
US7833545B2 (en) * 2003-04-29 2010-11-16 The General Hospital Corporation Methods and devices for the sustained release of multiple drugs
GB0417401D0 (en) 2004-08-05 2004-09-08 Controlled Therapeutics Sct Stabilised prostaglandin composition
WO2006084082A1 (en) * 2005-02-03 2006-08-10 Duramed Pharmaceuticals, Inc. Compositions of unconjugated estrogens and methods for their use
WO2006084083A2 (en) * 2005-02-03 2006-08-10 Duramed Pharmaceuticals, Inc. Devices for delivering agents to a vaginal tract
US8801694B2 (en) * 2005-08-11 2014-08-12 Massachusetts Institute Of Technology Intravesical drug delivery device
US20070077269A1 (en) * 2005-10-04 2007-04-05 Woodward John R Method of birth control and hormone regulation
CN103251449B (zh) * 2005-10-13 2016-03-02 斯恩蒂斯有限公司 载药包装物
GB0613333D0 (en) * 2006-07-05 2006-08-16 Controlled Therapeutics Sct Hydrophilic polyurethane compositions
GB0613638D0 (en) 2006-07-08 2006-08-16 Controlled Therapeutics Sct Polyurethane elastomers
US20080160065A1 (en) * 2006-07-12 2008-07-03 Janet Anne Halliday Drug delivery polymer with hydrochloride salt of clindamycin
GB0620685D0 (en) * 2006-10-18 2006-11-29 Controlled Therapeutics Sct Bioresorbable polymers
ES2696999T3 (es) 2007-06-26 2019-01-21 Allergan Pharmaceuticals Int Ltd Dispositivos de administración intravaginal de medicamentos para la administración de macromoléculas y medicamentos solubles en agua
JP5560200B2 (ja) 2007-12-11 2014-07-23 マサチューセッツ インスチテュート オブ テクノロジー 膀胱および他の身体の小嚢又は管腔を治療するための埋め込み型薬物供給デバイス
BRPI0917135A2 (pt) * 2008-08-09 2015-11-10 Massachusetts Inst Technology dispositivo médico para extensão e retenção em uma vesícula seminal, duto ejaculatório, próstata ou vaso deferente de um paciente, uso de um elastômero reabsorvível, e, dispositivo de bomba osmótica.
JP5695035B2 (ja) 2009-06-03 2015-04-01 フォーサイト・ビジョン5・インコーポレイテッドForsight Vision5,Inc. 前眼部薬物供給
EA023156B1 (ru) 2009-06-26 2016-04-29 ТАРИС Биомедикал ЛЛК Устройство для доставки лекарств
US9017312B2 (en) 2009-09-10 2015-04-28 Taris Biomedical Llc Implantable device for controlled drug delivery
US8580294B2 (en) 2010-10-19 2013-11-12 International Partnership For Microbicides Platinum-catalyzed intravaginal rings
EP2663300B1 (de) 2011-01-10 2023-03-08 TARIS Biomedical LLC Lidocain dosierungsschema zur verwendung bei einer anhaltenden behandlung von blasenschmerzen und schmerzhaftem harnabgang
WO2012106714A1 (en) 2011-02-04 2012-08-09 Taris Biomedical, Inc. Implantable device for controlled release of low solubility drug
WO2013040426A2 (en) 2011-09-14 2013-03-21 Forsight Labs, Llc Ocular insert apparatus and methods
TWI590843B (zh) 2011-12-28 2017-07-11 信迪思有限公司 膜及其製造方法
WO2014066775A1 (en) 2012-10-26 2014-05-01 Forsight Vision5, Inc. Ophthalmic system for sustained release of drug to eye
CN105163794B (zh) 2013-03-15 2020-03-27 塔里斯生物医药公司 具有药物可渗透部件的药物递送装置和方法
EP3010560B1 (de) 2013-06-21 2020-01-01 DePuy Synthes Products, Inc. Folien und verfahren zur herstellung
EP4234036A3 (de) 2013-08-19 2023-11-01 TARIS Biomedical LLC Vorrichtungen zur abgabe mehrteiliger wirkstoffe
CN104546668B (zh) * 2013-10-23 2019-03-05 国家卫生计生委科学技术研究所 液体硅橡胶为载体的药物缓控释系统的制备及应用
US10137031B2 (en) 2013-11-14 2018-11-27 International Partnership For Microbicides, Inc. Combination therapy intravaginal rings
EP3125964A4 (de) * 2014-04-01 2018-02-28 Poly-Med Inc. Verhütungsmittel und zugehörige vorrichtung
US20160296532A1 (en) 2015-04-13 2016-10-13 Forsight Vision5, Inc. Ocular Insert Composition of a Semi-Crystalline or Crystalline Pharmaceutically Active Agent
EP3285850A1 (de) 2015-04-23 2018-02-28 TARIS Biomedical LLC Wirkstoffabgabevorrichtungen mit einer wirkstoffdurchlässigen komponente und verfahren

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US3545439A (en) * 1968-01-04 1970-12-08 Upjohn Co Medicated devices and methods
US4291014A (en) * 1979-01-11 1981-09-22 Key Pharmaceuticals, Inc. Polymeric diffusion matrix containing estradiol diacetate
US4438139A (en) * 1979-08-14 1984-03-20 Key Pharmaceuticals, Inc. Polymeric diffusion matrix containing estrogens
SE8602666D0 (sv) * 1986-06-16 1986-06-16 Leo Ab Intravaginal devices

Also Published As

Publication number Publication date
DE69508791T2 (de) 1999-12-02
ES2133841T3 (es) 1999-09-16
AR002010A1 (es) 1998-01-07
NZ298490A (en) 1999-11-29
PE62796A1 (es) 1996-12-28
JPH10510825A (ja) 1998-10-20
FI119414B (fi) 2008-11-14
NO316707B1 (no) 2004-04-13
NO972798L (no) 1997-08-19
WO1996019196A1 (en) 1996-06-27
DK0799025T3 (da) 1999-10-18
GR3030614T3 (en) 1999-10-29
FI972579A0 (fi) 1997-06-17
EP0799025B1 (de) 1999-03-31
FI972579A (fi) 1997-06-17
ATE178204T1 (de) 1999-04-15
AU692659B2 (en) 1998-06-11
CA2207622C (en) 2006-10-17
US5855906A (en) 1999-01-05
CN1138526C (zh) 2004-02-18
EP0799025A1 (de) 1997-10-08
IL116433A (en) 2002-02-10
IL116433A0 (en) 1996-03-31
CA2207622A1 (en) 1996-06-27
AU4399196A (en) 1996-07-10
TR199501599A2 (tr) 1996-07-21
NO972798D0 (no) 1997-06-17
CN1170353A (zh) 1998-01-14

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