DE69519378D1 - Mehrfache verkapselung von öllösliche verbindungen - Google Patents
Mehrfache verkapselung von öllösliche verbindungenInfo
- Publication number
- DE69519378D1 DE69519378D1 DE69519378T DE69519378T DE69519378D1 DE 69519378 D1 DE69519378 D1 DE 69519378D1 DE 69519378 T DE69519378 T DE 69519378T DE 69519378 T DE69519378 T DE 69519378T DE 69519378 D1 DE69519378 D1 DE 69519378D1
- Authority
- DE
- Germany
- Prior art keywords
- polymer
- oleophilic
- oil
- cross
- oleophilic substance
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5089—Processes
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US26972094A | 1994-07-01 | 1994-07-01 | |
US08/439,787 US5938990A (en) | 1994-07-01 | 1995-05-24 | Encapsulation of oleophilic substances and compositions produced thereby |
PCT/EP1995/002468 WO1996001103A1 (en) | 1994-07-01 | 1995-06-24 | Multiple encapsulation of oleophilic substances |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69519378D1 true DE69519378D1 (de) | 2000-12-14 |
DE69519378T2 DE69519378T2 (de) | 2001-07-19 |
Family
ID=26953853
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69519378T Expired - Fee Related DE69519378T2 (de) | 1994-07-01 | 1995-06-24 | Mehrfache verkapselung von öllösliche verbindungen |
Country Status (10)
Country | Link |
---|---|
US (5) | US5938990A (de) |
EP (1) | EP0768870B1 (de) |
JP (1) | JPH10502621A (de) |
KR (1) | KR100392215B1 (de) |
CN (1) | CN1141935C (de) |
AT (1) | ATE197397T1 (de) |
DE (1) | DE69519378T2 (de) |
DK (1) | DK0768870T3 (de) |
ES (1) | ES2152409T3 (de) |
WO (1) | WO1996001103A1 (de) |
Families Citing this family (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9325445D0 (en) | 1993-12-13 | 1994-02-16 | Cortecs Ltd | Pharmaceutical formulations |
US5938990A (en) * | 1994-07-01 | 1999-08-17 | Roche Vitamins Inc. | Encapsulation of oleophilic substances and compositions produced thereby |
TW367247B (en) * | 1998-02-03 | 1999-08-21 | Otsuka Pharma Co Ltd | Storage container for Vitamin D solution and transfusion container |
US6303167B1 (en) * | 1998-11-09 | 2001-10-16 | Archer-Daniels-Midland Company | Method of producing vitamin powders |
US6770572B1 (en) | 1999-01-26 | 2004-08-03 | Alliedsignal Inc. | Use of multifunctional si-based oligomer/polymer for the surface modification of nanoporous silica films |
US6914073B2 (en) * | 1999-03-18 | 2005-07-05 | Bristol Myers Squibb Company | Vitamin formulation for cardiovascular health |
DK1106174T4 (en) * | 1999-12-09 | 2017-01-23 | Dsm Ip Assets Bv | Compositions containing fat-soluble vitamins |
DE60019239T3 (de) | 1999-12-09 | 2017-03-02 | Dsm Ip Assets B.V. | Fettlösliche Vitamine enthaltende Zusammensetzungen |
JP2001219487A (ja) * | 2000-02-10 | 2001-08-14 | Mitsubishi Heavy Ind Ltd | 紙製品の製造方法及び製造装置並びに紙接合用糊及び紙接合用糊のマイクロカプセル製造方法 |
US8178150B2 (en) | 2000-02-22 | 2012-05-15 | Suzanne Jaffe Stillman | Water containing soluble fiber |
US7892586B2 (en) | 2001-02-22 | 2011-02-22 | Suzanne Jaffe Stillman | Water containing soluble fiber |
WO2002026372A2 (en) | 2000-09-27 | 2002-04-04 | Verion Inc. | Instant water dissolvable encapsulate and process |
KR100439068B1 (ko) * | 2001-09-07 | 2004-07-05 | 주식회사 코리아나화장품 | 레티놀을 3중으로 안정화한 화장료 |
US7442227B2 (en) * | 2001-10-09 | 2008-10-28 | Washington Unniversity | Tightly agglomerated non-oxide particles and method for producing the same |
EP1455594B2 (de) † | 2001-12-20 | 2015-07-22 | Société des Produits Nestlé S.A. | Gelkapseln oder tabletten enthaltendes nahrungsmittel |
US6974592B2 (en) † | 2002-04-11 | 2005-12-13 | Ocean Nutrition Canada Limited | Encapsulated agglomeration of microcapsules and method for the preparation thereof |
WO2003092406A1 (en) * | 2002-05-02 | 2003-11-13 | Volker Kuellmer | Coated, agglomerated phytochemicals |
AU2003254055A1 (en) | 2002-07-23 | 2004-02-09 | Wm. Wrigley Jr. Company | Encapsulated flavors and chewing gum using same |
US20040115226A1 (en) * | 2002-12-12 | 2004-06-17 | Wenji Li | Free-flowing solid formulations with improved bio-availability of poorly water soluble drugs and process for making the same |
US20050214367A1 (en) * | 2004-03-22 | 2005-09-29 | Volker Kuellmer | Processes for making coated phytochemicals and tocopherols and products formed therefrom |
WO2005105040A2 (en) * | 2004-04-26 | 2005-11-10 | Micelle Products, Inc. | Water-soluble formulations of fat soluble vitamins and pharmaceutical agents and their applications |
US8075910B2 (en) * | 2004-05-20 | 2011-12-13 | Pbm Pharmaceuticals, Inc. | Oral compositions comprising edible oils and vitamins and/or minerals and methods for making oral compositions |
DE102004036437A1 (de) * | 2004-07-27 | 2006-03-23 | Röhm GmbH & Co. KG | Multipartikuläre Arzneiform für wenig lösliche Wirkstoffe, sowie ein Verfahren zur Herstellung der Arzneiform |
AU2006318357B2 (en) * | 2005-11-28 | 2009-09-24 | U.S. Nutraceuticals Llc Dba Valensa International | Algal and algal extract dietary supplement composition |
US7282225B1 (en) | 2006-09-27 | 2007-10-16 | Occular Technologies, Inc. | Composition and methods for improving retinal health |
GB201102557D0 (en) * | 2011-02-14 | 2011-03-30 | Univ Nottingham | Oil bodies |
EP3386320A1 (de) * | 2015-12-10 | 2018-10-17 | DSM IP Assets B.V. | Vitaminformulierung |
CN112641121B (zh) * | 2020-10-10 | 2022-04-19 | 广州玖洲胶囊生物科技有限公司 | 一种羟丙甲基纤维素和卡拉胶的填充空心胶囊制备方法 |
CN112753778A (zh) * | 2020-12-31 | 2021-05-07 | 大连臻鼎科技有限责任公司 | 一种高稳定性油脂微粒制品及其制备方法 |
Family Cites Families (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS507030B1 (de) * | 1970-04-02 | 1975-03-20 | ||
US4084012A (en) * | 1975-11-03 | 1978-04-11 | The Dow Chemical Company | Edible oil emulsions |
US4182778A (en) * | 1978-05-17 | 1980-01-08 | General Foods Corporation | Encapsulation of vitamin and mineral nutrients |
JPS574916A (en) * | 1980-05-28 | 1982-01-11 | Furointo Sangyo Kk | Activation of medical preparation |
US4389419A (en) * | 1980-11-10 | 1983-06-21 | Damon Corporation | Vitamin encapsulation |
US4415703A (en) * | 1981-01-13 | 1983-11-15 | Daicel Chemical Industries, Ltd. | Aqueous dispersion of a cellulose derivative |
DE3135329A1 (de) * | 1981-09-05 | 1983-03-24 | Basf Ag, 6700 Ludwigshafen | Verfahren zur herstellung von trockenpulvern oxidationsempfindlicher substanzen |
US5008254A (en) * | 1982-09-03 | 1991-04-16 | Weibel Michael K | Sugar beet pectins and their use in comestibles |
US4537783A (en) * | 1983-04-20 | 1985-08-27 | The Procter & Gamble Company | Control of particle size distribution during continuous heat-setting of meat analog |
US4670247A (en) * | 1983-07-05 | 1987-06-02 | Hoffman-Laroche Inc. | Process for preparing fat-soluble vitamin active beadlets |
IE59287B1 (en) * | 1984-02-10 | 1994-02-09 | Benzon Pharma As | Diffusion coated multiple-units dosage form |
US4826689A (en) * | 1984-05-21 | 1989-05-02 | University Of Rochester | Method for making uniformly sized particles from water-insoluble organic compounds |
IE58110B1 (en) * | 1984-10-30 | 1993-07-14 | Elan Corp Plc | Controlled release powder and process for its preparation |
US4734285A (en) * | 1985-10-28 | 1988-03-29 | The Dow Chemical Company | Sustained release compositions |
IE63321B1 (en) * | 1986-02-03 | 1995-04-05 | Elan Corp Plc | Drug delivery system |
GB2186485B (en) * | 1986-02-13 | 1988-09-07 | Ethical Pharma Ltd | Slow release formulation |
GB8613688D0 (en) * | 1986-06-05 | 1986-07-09 | Euro Celtique Sa | Pharmaceutical composition |
JPS6365945A (ja) * | 1986-09-05 | 1988-03-24 | Eisai Co Ltd | マイクロカプセルの製造方法 |
US4861627A (en) * | 1987-05-01 | 1989-08-29 | Massachusetts Institute Of Technology | Preparation of multiwall polymeric microcapsules |
US5051261A (en) * | 1987-11-24 | 1991-09-24 | Fmc Corporation | Method for preparing a solid sustained release form of a functionally active composition |
US4898734A (en) * | 1988-02-29 | 1990-02-06 | Massachusetts Institute Of Technology | Polymer composite for controlled release or membrane formation |
US5024842A (en) * | 1988-04-28 | 1991-06-18 | Alza Corporation | Annealed coats |
FR2663222A1 (fr) * | 1990-06-13 | 1991-12-20 | Medgenix Group Sa | Microcapsule de liquide huileux. |
ATE117202T1 (de) * | 1991-01-28 | 1995-02-15 | Hoffmann La Roche | Vitamin enthaltende formulierungen und deren herstellung. |
US5223268A (en) * | 1991-05-16 | 1993-06-29 | Sterling Drug, Inc. | Low solubility drug-coated bead compositions |
EP0595030A3 (de) * | 1992-10-01 | 1995-06-07 | Tanabe Seiyaku Co | Mehrkern-Mikrosphären mit verzögerter Wirkstoffabgabe und Verfahren zu deren Herstellung. |
ES2068762B1 (es) * | 1993-07-21 | 1995-12-01 | Lipotec Sa | Un nuevo preparado farmaceutico para mejorar la biodisponibilidad de drogas de dificil absorcion y procedimiento para su obtencion. |
US5938990A (en) * | 1994-07-01 | 1999-08-17 | Roche Vitamins Inc. | Encapsulation of oleophilic substances and compositions produced thereby |
-
1995
- 1995-05-24 US US08/439,787 patent/US5938990A/en not_active Expired - Fee Related
- 1995-06-24 AT AT95924932T patent/ATE197397T1/de not_active IP Right Cessation
- 1995-06-24 ES ES95924932T patent/ES2152409T3/es not_active Expired - Lifetime
- 1995-06-24 WO PCT/EP1995/002468 patent/WO1996001103A1/en active IP Right Grant
- 1995-06-24 EP EP95924932A patent/EP0768870B1/de not_active Expired - Lifetime
- 1995-06-24 DK DK95924932T patent/DK0768870T3/da active
- 1995-06-24 DE DE69519378T patent/DE69519378T2/de not_active Expired - Fee Related
- 1995-06-24 CN CNB95193886XA patent/CN1141935C/zh not_active Expired - Fee Related
- 1995-06-24 KR KR1019960707605A patent/KR100392215B1/ko not_active IP Right Cessation
- 1995-06-24 JP JP8503655A patent/JPH10502621A/ja not_active Ceased
-
1997
- 1997-06-02 US US08/867,372 patent/US5925381A/en not_active Expired - Fee Related
-
1998
- 1998-01-16 US US09/008,251 patent/US6001554A/en not_active Expired - Fee Related
-
1999
- 1999-11-12 US US09/438,640 patent/US6150086A/en not_active Expired - Fee Related
- 1999-11-12 US US09/434,556 patent/US6146825A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
EP0768870B1 (de) | 2000-11-08 |
WO1996001103A1 (en) | 1996-01-18 |
US6146825A (en) | 2000-11-14 |
ATE197397T1 (de) | 2000-11-11 |
US6150086A (en) | 2000-11-21 |
CN1141935C (zh) | 2004-03-17 |
US6001554A (en) | 1999-12-14 |
KR970703755A (ko) | 1997-08-09 |
US5925381A (en) | 1999-07-20 |
DE69519378T2 (de) | 2001-07-19 |
KR100392215B1 (ko) | 2003-11-20 |
JPH10502621A (ja) | 1998-03-10 |
DK0768870T3 (da) | 2001-02-05 |
ES2152409T3 (es) | 2001-02-01 |
US5938990A (en) | 1999-08-17 |
CN1151694A (zh) | 1997-06-11 |
EP0768870A1 (de) | 1997-04-23 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8327 | Change in the person/name/address of the patent owner |
Owner name: DSM IP ASSETS B.V., TE HEERLEN, NL |
|
8339 | Ceased/non-payment of the annual fee |